Aim: Focusing on the feature of genetic data, such as privacy, evolution, multi-measure, heterogeneity, systematicness, and so on, combing molecular biology experiments and clinical scientific issues contribute to the reestablishment of dynamic evolving molecular networks of disease, the scientific basis and informatics platform for the precise diagnosis, treatment and intelligent health management of diseases. Thus, our specific work follow the three aspects:
Zhan C, Liu K, Zhang Y, Zhang Y, He M, Wu R, Bi C, Shen B. Myocardial infarction unveiled: Key miRNA players screened by a novel lncRNA-miRNA-mRNA network model. Comput Biol Med. 2023 Apr 28;160:106987. doi: 10.1016/j.compbiomed.2023.106987. Epub ahead of print. PMID: 37141653.
Shen K, Din AU, Sinha B, Zhou Y, Qian F, Shen B. Translational informatics for human microbiota: data resources, models and applications. Brief Bioinform. 2023 May 4:bbad168. doi: 10.1093/bib/bbad168. Epub ahead of print. PMID: 37141135.
Ullah A, Wang MJ, Wang YX, Shen B. CXC chemokines influence immune surveillance in immunological disorders: Polycystic ovary syndrome and endometriosis. Biochim Biophys Acta Mol Basis Dis. 2023 Mar 30;1869(5):166704. doi: 10.1016/j.bbadis.2023.166704. Epub ahead of print. PMID: 37001703.
Kapoor B, Gulati M, Gupta R, Singla RK. Microbiota dysbiosis and myasthenia gravis: Do all roads lead to Rome? Autoimmun Rev. 2023 May;22(5):103313. doi: 10.1016/j.autrev.2023.103313. Epub 2023 Mar 12. PMID: 36918089.
Singla RK, Joon S, Sinha B, Kamal MA, Simal-Gandara J, Xiao J, Shen B. Current trends in natural products for the treatment and management of dementia: Computational to clinical studies. Neurosci Biobehav Rev. 2023 Apr;147:105106. doi: 10.1016/j.neubiorev.2023.105106. Epub 2023 Feb 23. PMID: 36828163.