• About us 


Aim: Focusing on the feature of genetic data, such as privacy, evolution, multi-measure, heterogeneity, systematicness, and so on, combing molecular biology experiments and clinical scientific issues contribute to the reestablishment of dynamic evolving molecular networks of disease, the scientific basis and informatics platform for the precise diagnosis, treatment and intelligent health management of diseases. Thus, our specific work follow the three aspects:

  1. Establishing the model and platform for disease biomedical data sharing and security, such as the disease-specific ontology; the ontology-based data sharing model and the data security protection,  database and knowledge base for a series of disease, etc;
  2. Establishing different omits, such as genomics, proteomics, metabonomics, microbiome, single-cell omics, physiological phenotypes, and clinical phenotypes, cheminformatics, etc,  unique ecological network models and data analysis platforms of various omits;
  3. Establishing knowledge-guided biomedical and health intelligence engineering, and promoting the transformation and application of informatics in chronic disease management, hierarchical diagnosis and treatment, and personalized health management.

• Publication 


Zong H, Wu R, Cha J, Feng W, Wu E, Li J, Shao A, Tao L, Li Z, Tang B, Shen B. Advancing Chinese biomedical text mining with community challenges. J Biomed Inform. 2024 Aug 27;157:104716. doi: 10.1016/j.jbi.2024.104716. Epub ahead of print. PMID: 39197732.

Liu K, Xu X, Sun L, Li H, Jin Y, Ma X, Shen B, Martin C. Proteomics profiling reveals lipid metabolism abnormalities during oogenesis in unexplained recurrent pregnancy loss. Front Immunol. 2024 Aug 8;15:1397633. doi: 10.3389/fimmu.2024.1397633. PMID: 39176081; PMCID: PMC11339622.

Xie W, Sharma A, Kaushik H, Sharma L, Nistha, Anwer MK, Sachdeva M, Elossaily GM, Zhang Y, Pillappan R, Kaur M, Behl T, Shen B, Singla RK. Shaping the future of gastrointestinal cancers through metabolic interactions with host gut microbiota. Heliyon. 2024 Jul 27;10(15):e35336. doi: 10.1016/j.heliyon.2024.e35336. PMID: 39170494; PMCID: PMC11336605.

Li JK, Tang T, Zong H, Wu EM, Zhao J, Wu RR, Zheng XN, Zhang H, Li YF, Zhou XH, Zhang CC, Zhang ZL, Zhang YH, Feng WZ, Zhou Y, Wang J, Zhu QY, Deng Q, Zheng JM, Yang L, Wei Q, Shen BR. Intelligent medicine in focus: the 5 stages of evolution in robot-assisted surgery for prostate cancer in the past 20 years and future implications. Mil Med Res. 2024 Aug 21;11(1):58. doi: 10.1186/s40779-024-00566-z. PMID: 39164787; PMCID: PMC11337898.

Batool Z, Kamal MA, Shen B. Advancements in triple-negative breast cancer sub-typing, diagnosis and treatment with assistance of artificial intelligence : a focused review. J Cancer Res Clin Oncol. 2024 Aug 6;150(8):383. doi: 10.1007/s00432-024-05903-2. PMID: 39103624; PMCID: PMC11300496.