4
Li J, Xu J, Yang T, Chen J, Li F, Shen B, Fan C. Genome-wide methylation analyses of human sperm unravel novel differentially methylated regions in asthenozoospermia. Epigenomics. 2022 Aug 25. doi: 10.2217/epi-2022-0122. Epub ahead of print. PMID: 36004499.
3
Li Y, Jiang Y, Li Z, Yu Y, Chen J, Jia W, Kaow Ng Y, Ye F, Cheng Li S, Shen B. Both simulation and sequencing data reveal coinfections with multiple SARS-CoV-2 variants in the COVID-19 pandemic. Comput Struct Biotechnol J. 2022;20:1389-1401. doi: 10.1016/j.csbj.2022.03.011. Epub 2022 Mar 18. PMID: 35342534; PMCID: PMC8930779.
2
Long M, Shen B. Evolution of genes and genomes: an emerging paradigm in life science. Sci China Life Sci. 2019 Apr;62(4):435-436. doi: 10.1007/s11427-018-9448-x. Epub 2019 Apr 16. PMID: 30929192.
1
Zhang W, Gao Y, Long M, Shen B. Origination and evolution of orphan genes and de novo genes in the genome of Caenorhabditis elegans. Sci China Life Sci. 2019 Apr;62(4):579-593. doi: 10.1007/s11427-019-9482-0. Epub 2019 Mar 21. PMID: 30919281.
13
Sultana A, Alam MS, Liu X, Sharma R, Singla RK, Gundamaraju R, Shen B. Single-cell RNA-seq analysis to identify potential biomarkers for diagnosis, and prognosis of non-small cell lung cancer by using comprehensive bioinformatics approaches. Transl Oncol. 2022 Nov 16;27:101571. doi: 10.1016/j.tranon.2022.101571. Epub ahead of print. PMID: 36401966.
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Lin Y, Qi X, Chen J, Shen B. Multivariate competing endogenous RNA network characterization for cancer microRNA biomarker discovery: a novel bioinformatics model with application to prostate cancer metastasis. Precis Clin Med. 2022 Jan 10;5(1):pbac001. doi: 10.1093/pcmedi/pbac001. PMID: 35821682; PMCID: PMC9267254.
11
Lin Y, Wang L, Ge W, Hui Y, Zhou Z, Hu L, Pan H, Huang Y, Shen B. Multi-omics network characterization reveals novel microRNA biomarkers and mechanisms for diagnosis and subtyping of kidney transplant rejection. J Transl Med. 2021 Aug 13;19(1):346. doi: 10.1186/s12967-021-03025-8. PMID: 34389032; PMCID: PMC8361655.
10
Qian F, Wang J, Wang Y, Gao Q, Yan W, Lin Y, Shen L, Xie Y, Jiang X, Shen B. MiR-378a-3p as a putative biomarker for hepatocellular carcinoma diagnosis and prognosis: Computational screening with experimental validation. Clin Transl Med. 2021 Feb;11(2):e307. doi: 10.1002/ctm2.307. PMID: 33634974; PMCID: PMC7882078.
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Lin Y, Miao Z, Zhang X, Wei X, Hou J, Huang Y, Shen B. Identification of Key MicroRNAs and Mechanisms in Prostate Cancer Evolution Based on Biomarker Prioritization Model and Carcinogenic Survey. Front Genet. 2021 Jan 15;11:596826. doi: 10.3389/fgene.2020.596826. PMID: 33519899; PMCID: PMC7844321.
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Qi X, Lin Y, Liu X, Chen J, Shen B. Biomarker Discovery for the Carcinogenic Heterogeneity Between Colon and Rectal Cancers Based on lncRNA-Associated ceRNA Network Analysis. Front Oncol. 2020 Oct 30;10:535985. doi: 10.3389/fonc.2020.535985. PMID: 33194594; PMCID: PMC7662689.
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Singla RK, Sultana A, Alam MS, Shen B. Regulation of Pain Genes-Capsaicin vs Resiniferatoxin: Reassessment of Transcriptomic Data. Front Pharmacol. 2020 Oct 29;11:551786. doi: 10.3389/fphar.2020.551786. PMID: 33192502; PMCID: PMC7658921.
6
Qi X, Lin Y, Chen J, Shen B. The landscape of emerging ceRNA crosstalks in colorectal cancer: Systems biological perspectives and translational applications. Clin Transl Med. 2020 Aug;10(4):e153. doi: 10.1002/ctm2.153. PMID: 32898321; PMCID: PMC7426901.
5
Hu H, He X, Zhang Y, Wu R, Chen J, Lin Y, Shen B. MicroRNA Alterations for Diagnosis, Prognosis, and Treatment of Osteoporosis: A Comprehensive Review and Computational Functional Survey. Front Genet. 2020 Mar 3;11:181. doi: 10.3389/fgene.2020.00181. PMID: 32194637; PMCID: PMC7063117.
4
Wu R, Lin Y, Liu X, Zhan C, He H, Shi M, Jiang Z, Shen B. Phenotype-genotype network construction and characterization: a case study of cardiovascular diseases and associated non-coding RNAs. Database (Oxford). 2020 Jan 1;2020:baz147. doi: 10.1093/database/baz147. PMID: 31942979; PMCID: PMC6964217.
3
Qi X, Yu C, Wang Y, Lin Y, Shen B. Network vulnerability-based and knowledge-guided identification of microRNA biomarkers indicating platinum resistance in high-grade serous ovarian cancer. Clin Transl Med. 2019 Oct 29;8(1):28. doi: 10.1186/s40169-019-0245-6. PMID: 31664600.
2
Qi X, Lin Y, Chen J, Shen B. Decoding competing endogenous RNA networks for cancer biomarker discovery. Brief Bioinform. 2019 Jan 30;10.1093/bib/bbz006. doi: 10.1093/bib/bbz006. [Epub ahead of print]. PMID: 30715152.
1
Lin Y, Chen F, Shen L, Tang X, Du C, Sun Z, Ding H, Chen J, Shen B. Biomarker microRNAs for prostate cancer metastasis: screened with a network vulnerability analysis model. <i>J Transl Med</i>. 2018 May 21;16(1):134. doi: 10.1186/s12967-018-1506-7. PMID: 29784056; PMCID: PMC5963164.
17
Ullah A, Wang MJ, Wang YX, Shen B. CXC chemokines influence immune surveillance in immunological disorders: Polycystic ovary syndrome and endometriosis. Biochim Biophys Acta Mol Basis Dis. 2023 Mar 30;1869(5):166704. doi: 10.1016/j.bbadis.2023.166704. Epub ahead of print. PMID: 37001703.
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Kapoor B, Gulati M, Gupta R, Singla RK. Microbiota dysbiosis and myasthenia gravis: Do all roads lead to Rome? Autoimmun Rev. 2023 May;22(5):103313. doi: 10.1016/j.autrev.2023.103313. Epub 2023 Mar 12. PMID: 36918089.
15
Singla RK, Behzad S, Khan J, Tsagkaris C, Gautam RK, Goyal R, Chopra H, Shen B. Natural Kinase Inhibitors for the Treatment and Management of Endometrial/Uterine Cancer: Preclinical to Clinical Studies. Front Pharmacol. 2022 Feb 21;13:801733. doi: 10.3389/fphar.2022.801733. PMID: 35264951; PMCID: PMC8899191.
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Singla RK, He X, Chopra H, Tsagkaris C, Shen L, Kamal MA, Shen B. Natural Products for the Prevention and Control of the COVID-19 Pandemic: Sustainable Bioresources. Front Pharmacol. 2021 Dec 1;12:758159. doi: 10.3389/fphar.2021.758159. PMID: 34925017; PMCID: PMC8671886.
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Singla RK, Sai CS, Chopra H, Behzad S, Bansal H, Goyal R, Gautam RK, Tsagkaris C, Joon S, Singla S, Shen B. Natural Products for the Management of Castration-Resistant Prostate Cancer: Special Focus on Nanoparticles Based Studies. Front Cell Dev Biol. 2021 Nov 5;9:745177. doi: 10.3389/fcell.2021.745177. PMID: 34805155; PMCID: PMC8602797.
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Singla RK, Ashraf GM, Ganash M, Bhat G V, Shen B. Physicochemical, Interaction & Topological Descriptors vs. hMAO-A Inhibition of Aplysinopsin Analogs: A Boulevard to the Discovery of Semi-Synthetic Anti-Depression Agents. Curr Drug Metab. 2021 Oct 15. doi: 10.2174/1389200222666211015155014. Epub ahead of print. PMID: 34779368.
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Singla RK. Secondary Metabolites as Treatment of Choice for Metabolic Disorders and Infectious Diseases and their Metabolic Profiling - Part 3. Curr Drug Metab. 2021;22(6):412-414. doi: 10.2174/138920022206210708103019. PMID: 34455943.
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Joon S, Singla RK, Shen B, Kamal MA. QSCR Analysis of Cytotoxicity of 6-Fluoro-3-(4H-1,2,4-triazol-3-yl)quinolin-4(1H)-ones on Chinese Hamster Ovary Cell Line: Design of REPUBLIC1986. Curr Med Chem. 2021 Jun 23. doi: 10.2174/0929867328666210623150552. Epub ahead of print. PMID: 34165404.
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Li Y, Shen L, Huang C, Li X, Chen J, Li SC, Shen B. Altered nitric oxide induced by gut microbiota reveals the connection between central precocious puberty and obesity. Clin Transl Med. 2021 Feb;11(2):e299. doi: 10.1002/ctm2.299. PMID: 33634977; PMCID: PMC7842634.
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Singla RK, Guimarães AG, Zengin G. Editorial: Application of Plant Secondary Metabolites to Pain Neuromodulation. Front Pharmacol. 2021 Jan 14;11:623399. doi: 10.3389/fphar.2020.623399. PMID: 33519489; PMCID: PMC7841409.
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Shen B, Singla RK. Secondary Metabolites as Treatment of Choice for Metabolic Disorders and Infectious Diseases & their Metabolic Profiling-Part 2. Curr Drug Metab. 2020;21(14):1070-1071. doi: 10.2174/138920022114201230142204. PMID: 33413055.
6
Sultana A, Singla RK, He X, Sun Y, Alam MS, Shen B. Topical Capsaicin for the Treatment of Neuropathic Pain. Curr Drug Metab. 2020 Nov 16. doi: 10.2174/1389200221999201116143701. Epub ahead of print. PMID: 33198614.
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Singla RK. Secondary Metabolites as Treatment of Choice for Metabolic Disorders and Infectious Diseases and their Metabolic Profiling: Part 1. Curr Drug Metab. 2020;21(7):480-481. doi: 10.2174/138920022107200925101631. PMID: 33172364.
4
Shen B, Singla RK, Agarwal T, Xuefei H. Herbal Resources to Combat a Progressive & Degenerative Nervous System Disorder - Parkinson's Disease. Curr Drug Targets. 2020 Oct 13. doi: 10.2174/1389450121999201013155202. Epub ahead of print. PMID: 33050857.
3
Shen L, Shen K, Bai J, Wang J, Singla RK, Shen B. Data-driven microbiota biomarker discovery for personalized drug therapy of cardiovascular disease. Pharmacol Res. 2020 Sep 29;161:105225. doi: 10.1016/j.phrs.2020.105225. Epub ahead of print. PMID: 33007417.
2
Singla RK, Shen B. In Silico ADME-T Evaluation of Natural DPP-IV Inhibitors for Rational Drug Design against Diabetes. Curr Drug Metab. 2020 Sep 1. doi: 10.2174/1389200221999200901202945. Epub ahead of print. PMID: 32875983.
1
Zhou J, Oldfield CJ, Yan W, Shen B, Dunker AK. Identification of Intrinsic Disorder in Complexes from the Protein Data Bank. ACS Omega. 2020 Jul 14;5(29):17883-17891. doi: 10.1021/acsomega.9b03927. PMID: 32743159; PMCID: PMC7391252.
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Goyal R, Gautam RK, Chopra H, Dubey AK, Singla RK, Rayan RA, Kamal MA. Comparative highlights on MERS-CoV, SARS-CoV-1, SARS-CoV-2, and NEO-CoV. EXCLI J. 2022 Sep 29;21:1245-1272. doi: 10.17179/excli2022-5355. PMID: 36483910; PMCID: PMC9727256.
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Sharma R, Jadhav M, Choudhary N, Kumar A, Rauf A, Gundamaraju R, AlAsmari AF, Ali N, Singla RK, Sharma R, Shen B. Deciphering the impact and mechanism of Trikatu, a spices-based formulation on alcoholic liver disease employing network pharmacology analysis and <i>in vivo</i> validation. Front Nutr. 2022 Nov 16;9:1063118. doi: 10.3389/fnut.2022.1063118. PMID: 36466417; PMCID: PMC9709420.
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Singla RK, Sharma P, Kumar D, Gautam RK, Goyal R, Tsagkaris C, Dubey AK, Bansal H, Sharma R, Shen B. The role of nanomaterials in enhancing natural product translational potential and modulating endoplasmic reticulum stress in the treatment of ovarian cancer. Front Pharmacol. 2022 Oct 26;13:987088. doi: 10.3389/fphar.2022.987088. PMID: 36386196; PMCID: PMC9643842.
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Singla RK, Dhonchak K, Sodhi RK, Arockia Babu M, Madan J, Madaan R, Kumar S, Sharma R, Shen B. Bergenin ameliorates cognitive deficits and neuropathological alterations in sodium azide-induced experimental dementia. Front Pharmacol. 2022 Sep 29;13:994018. doi: 10.3389/fphar.2022.994018. PMID: 36249784; PMCID: PMC9556967.
3
Mondal H, Parvanov ED, Singla RK, Rayan RA, Nawaz FA, Ritschl V, Eibensteiner F, Siva Sai C, Cenanovic M, Devkota HP, Hribersek M, De R, Klager E, Kletecka-Pulker M, Völkl-Kernstock S, Khalid GM, Lordan R, Găman MA, Shen B, Stamm T, Willschke H, Atanasov AG. Twitter-based crowdsourcing: What kind of measures can help to end the COVID-19 pandemic faster? Front Med (Lausanne). 2022 Sep 16;9:961360. doi: 10.3389/fmed.2022.961360. PMID: 36186802; PMCID: PMC9523003.
2
Singla RK, Wang X, Gundamaraju R, Joon S, Tsagkaris C, Behzad S, Khan J, Gautam R, Goyal R, Rakmai J, Dubey AK, Simal-Gandara J, Shen B. Natural products derived from medicinal plants and microbes might act as a game-changer in breast cancer: a comprehensive review of preclinical and clinical studies. Crit Rev Food Sci Nutr. 2022 Jul 15:1-45. doi: 10.1080/10408398.2022.2097196. Epub ahead of print. PMID: 35838143.
1
Singla RK, Dhir V, Madaan R, Kumar D, Singh Bola S, Bansal M, Kumar S, Dubey AK, Singla S, Shen B. The Genus Alternanthera: Phytochemical and Ethnopharmacological Perspectives. Front Pharmacol. 2022 Apr 11;13:769111. doi: 10.3389/fphar.2022.769111. PMID: 35479320; PMCID: PMC9036189.