Since 2018, he has been Professor & Executive Director General of Institutes for Systems Genetics, West China Hospital of Sichuan University. In 1997, he graduated from Fudan University with a Ph.D. and served as an associate professor in 1999. In 2000, he moved to biomedical informatics area and worked at the University of Tampere, Finland (2004 Assistant Professor/Associate Professor), Tongji University (2005-2008, Professor, Ph.D.) and Soochow University (2008-2018, professor, director of Center for Systems Biology) and so on. Since returning to China in 2008, he has hosted more than 10 major projects and national fund projects, and published more than 100 papers in international journals such as Bioinformatics, Genome Biology, Journal of Translational Medicine, Nucleic Acids Research, Briefs in Bioinformatics. He has published 4 works in English and 1 work in Chinese. He is also a professor at the Institute of Systems Biology in Seattle, the executive director & vice chairman of the China Society of Bioinformatics, the executive director of the Medical Information Branch of the Chinese Medical Association, the vice chairman of the Computing Systems Biology Branch of the China Operations Research Society, the first director of the Information Society, the second-instance expert of the Fund Committee, and the expert of the major project of precision medicine for the Health Planning Commission, etc. He has trained more than 50 doctoral and master students after returning to China. Since 2012, he has been advocating translational biomedical informatics, promoting the fusion of medical and bioinformatics and medical informatics internationally. He is the founding chairman of the International Conference on Transforming Biomedical Informatics (ICTBI).