Welcome to GVDoscc
Oral squamous cell carcinoma is a malignant tumor idiopathic in the oral cavity, which is the most malignant and most harmful tumor of head and neck. At present, more and more researches focus on the subtype analysis and immunotherapy of OSCC. To understand the heterogeneity of OSCC, a database for integrating fragmented data and unifying annotations is desperately needed. This research sorting data and knowledge in PubMed literature through NLP and manual work, and successfully established a genetic variation database for OSCC.
Statistics
GVDoscc contains 1,672 entries of somatic genetic variations, including 329 epimutations/methylations, 600 point mutations (comprising 369 single nucleotide polymorphisms [SNPs]), 90 insertion-deletion mutations (indel mutations), 336 copy number variations (CNVs), 28 instances of loss of heterozygosity (LOH), 108 other variants, and 181 unspecified gene mutations, all manually extracted from 384 original research articles between January 1991 and December 2023, providing a reliable and accurate open-source dataset for OSCC researchers.
