Sepsis

Sepsis, a serious organ dysfunction syndrome caused by infection, is one of the leading causes of human mortality and disability worldwide, and accounts for an in-hospital death rate of 10-20%. The situation is worse in children, especially newborn, where death due to neonatal sepsis was almost 16% of total neonatal mortality in 2013.

Sepsis Biomarker

Biomarkers, which are indicators of biological states or conditions, have been widely used to improve the diagnosis, therapy and prognosis of human sepsis. Thus, many researchers including our group have focused on the identification of sepsis biomarkers . Until 2018-11-28, 8936 related papers were reported on the Web of science database.

Update dialogue

  • August 20th, 2023——MetaSepsisBase has been updated to MetaSepsisCDSS comprising 427 sepsis-related biomarkers until July 31st, 2023, totaling 644 records, which serves as a clinical decision support platform for personalized diagnosis and treatment of human sepsis.

  • July 31st, 2022---MetaSepsisBase was updated to include 320 distinct biomarkers for sepsis in adults, children, and neonates, as well as 450 unique records.

  • November, 2018---210 different Adult sepsis biomarkers have been included

  • November, 2018---11 different Children sepsis biomarkers have been included

  • November, 2016---66 different neonatal biomarkers have been included

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