Amyotrophic Lateral SclerosisAmyotrophic Lateral Sclerosis(ALS) is a specific disease that causes the death of neurons controlling voluntary muscles.[4][9] ALS is characterized by stiff muscles, muscle twitching, and gradually worsening weakness due to muscles decreasing in size.[2] It may begin with weakness in the arms or legs, or with difficulty speaking or swallowing.[10] About half of the people affected develop at least mild difficulties with thinking and behavior and most people experience pain.[11][12] Most eventually lose the ability to walk, use their hands, speak, swallow, and breathe.[5]
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The search result for the NDD Category "Amyotrophic Lateral Sclerosis"
A total of 475 results found based on your keywordsRF_ID | Disease Name | Species | RF_Name | Association | Condition | PMID |
---|---|---|---|---|---|---|
4 | Amyotrophic Lateral Sclerosis | human | A90V TDP-43 variant | RF | 18505686 | |
22 | Amyotrophic Lateral Sclerosis | human | APOE-2 | PF | 15657798 | |
26 | Amyotrophic Lateral Sclerosis | human | ATAXIN2 | RF | ≥ 31 CAG-repeat length | 22425256 |
31 | Amyotrophic lateral sclerosis | human | ATRN | RF | 27455347 | |
32 | Amyotrophic lateral sclerosis | human | ATXN1 | RF | 25023141 | |
33 | Amyotrophic lateral sclerosis | human | ATXN2 | RF | 30847648 | |
33 | Amyotrophic lateral sclerosis | human | ATXN2 | RF | 26208502 | |
33 | Amyotrophic lateral sclerosis | human | ATXN2 | RF | 23197749 | |
33 | Amyotrophic Lateral Sclerosis | human | ATXN2 | RF | ATXN2 polyQ repeat expansions greater than 27 | 21741123 |
33 | Amyotrophic Lateral Sclerosis | human | ATXN2 | RF | ATXN2 high-length alleles (≥29 CAG repeats) | 21670397 |
33 | Amyotrophic Lateral Sclerosis | human | ATXN2 | RF | ATXN2 high-length alleles (≥29 CAG repeats) | 21670397 |
38 | Amyotrophic lateral sclerosis | human | BIRC6 | RF | 27455347 | |
40 | Amyotrophic lateral sclerosis | human | C1QTNF7 | RF | 27455347 | |
43 | Amyotrophic lateral sclerosis | human | C7orf57 | RF | 25023141 | |
44 | Amyotrophic lateral sclerosis | human | C9orf72 | RF | 25023141 | |
44 | Amyotrophic lateral sclerosis | human | C9orf72 | RF | 29528390 | |
44 | Amyotrophic Lateral Sclerosis | human | C9orf72 | RF | 20801718 | |
58 | Amyotrophic Lateral Sclerosis | human | CHGB | RF | 20007371 | |
58 | Amyotrophic Lateral Sclerosis | human | CHGB | RF | 20007371 | |
61 | Amyotrophic lateral sclerosis | human | CHRNA4 | RF | 22873564 | |
75 | Amyotrophic lateral sclerosis | human | CREB3L2 | RF | 27455347 | |
79 | Amyotrophic lateral sclerosis | human | CX3CR1 | RF | 24806473 | |
79 | Amyotrophic lateral sclerosis | human | CX3CR1 | RF | 24806473 | |
79 | Amyotrophic lateral sclerosis | human | CX3CR1 | RF | 24806473 | |
86 | Amyotrophic lateral sclerosis | human | DCC | RF | 27455347 | |
89 | Amyotrophic lateral sclerosis | human | DISC1 | RF | 25023141 | |
91 | Amyotrophic lateral sclerosis | human | DPP6 | RF | 25023141 | |
92 | Amyotrophic lateral sclerosis | human | DPYSL3(CRMP4) | RF | 23568759 | |
101 | Amyotrophic lateral sclerosis | human | ERp57/PDIA3 | RF | 25913742 | |
110 | Amyotrophic lateral sclerosis | human | FUS | RF | 28054830 | |
114 | Amyotrophic lateral sclerosis | human | GARS | RF | 30661401 | |
128 | Amyotrophic Lateral Sclerosis | human | HFE | RF | Genotype:GC | 20642794 |
128 | Amyotrophic Lateral Sclerosis | human | HFE | RF | Genotype:GC/GG | 20642794 |
128 | Amyotrophic Lateral Sclerosis | human | HFE | RF | Genotype:G allele frequency | 20642794 |
133 | Amyotrophic Lateral Sclerosis | human | HLA-DRA/HLA-DRB5 | RF | the AA genotype at rs9268856 | 28131168 |
149 | Amyotrophic Lateral Sclerosis | human | Intergenic | RF | The estimations using the proposed method (unadjusted estimates) | 19740415 |
149 | Amyotrophic Lateral Sclerosis | human | Intergenic | RF | The estimations using the proposed method (adjusted estimates) | 19740415 |
150 | Amyotrophic Lateral Sclerosis | human | Intergenic and SHROOM3 | RF | The estimations using the proposed method (unadjusted estimates) | 19740415 |
151 | Amyotrophic Lateral Sclerosis | human | Intergenic and SHROOM4 | RF | The estimations using the proposed method (adjusted estimates) | 19740415 |
154 | Amyotrophic lateral sclerosis | human | ITPR2 | RF | 25023141 | |
157 | Amyotrophic lateral sclerosis | human | KIF5A | RF | 27455347 | |
163 | Amyotrophic Lateral Sclerosis | human | LOC107987057 | RF | 20801718 | |
163 | Amyotrophic Lateral Sclerosis | human | LOC107987057 | RF | 20801717 | |
163 | Amyotrophic Lateral Sclerosis | human | LOC107987057 | RF | In the joint analysis | 20801717 |
164 | Amyotrophic Lateral Sclerosis | human | LOC107987057,LOC112268043 | RF | 20801717 | |
164 | Amyotrophic Lateral Sclerosis | human | LOC107987057,LOC112268043 | RF | In the joint analysis | 20801717 |
165 | Amyotrophic Lateral Sclerosis | human | LOC112268043,LOC107987057 | RF | 20801718 | |
169 | Amyotrophic Lateral Sclerosis | human | M1(C/C) | RF | 17503480 | |
170 | Amyotrophic Lateral Sclerosis | human | M5(A/A) | PF | 17503480 | |
171 | Amyotrophic Lateral Sclerosis | human | M6(T/T) | RF | 17503480 | |
183 | Amyotrophic lateral sclerosis | human | MOB3B | RF | 25023141 | |
183 | Amyotrophic Lateral Sclerosis | human | MOB3B | RF | 20801718 | |
190 | Amyotrophic Lateral Sclerosis | human | MTHFR(T677T) | RF | 22385294 | |
191 | Amyotrophic Lateral Sclerosis | human | MTHFR(T677T/A1298A) | RF | 22385294 | |
194 | Amyotrophic lateral sclerosis | human | NEK1 | RF | 27455347 | |
194 | Amyotrophic lateral sclerosis | human | NEK1 | RF | 27455347 | |
194 | Amyotrophic lateral sclerosis | human | NEK1 | RF | 27455347 | |
194 | Amyotrophic lateral sclerosis | human | NEK1 | RF | 27455347 | |
198 | Amyotrophic Lateral Sclerosis | human | NIPA1 | RF | 22378146 | |
210 | Amyotrophic lateral sclerosis | human | P4HB/PDIA1 | RF | 25913742 | |
217 | Amyotrophic lateral sclerosis | human | PEAK1 | RF | 27455347 | |
219 | Amyotrophic lateral sclerosis | human | PFN1 | RF | 24309268 | |
227 | Amyotrophic Lateral Sclerosis | human | PON1 Q192R(major allele is Q) | RF | Recessive (RR vs other) | 16822965 |
227 | Amyotrophic Lateral Sclerosis | human | PON1 Q192R(major allele is Q) | RF | Additive | 16822965 |
227 | Amyotrophic Lateral Sclerosis | human | PON1 Q192R(major allele is Q) | RF | Dominant (RR and QR vs QQ) | 16822965 |
228 | Amyotrophic Lateral Sclerosis | human | PON2 C311S (major allele is S) | RF | Additive | 16822965 |
228 | Amyotrophic Lateral Sclerosis | human | PON2 C311S (major allele is S) | RF | Dominant (CC and CS vs SS) | 16822965 |
253 | Amyotrophic Lateral Sclerosis | human | SMN1 | RF | one copy | 16931506 |
253 | Amyotrophic Lateral Sclerosis | human | SMN1 | RF | three copies | 16931506 |
253 | Amyotrophic Lateral Sclerosis | human | SMN1 | RF | one or three copies of SMN1 gene were pooled | 16931506 |
253 | Amyotrophic Lateral Sclerosis | human | SMN1 | RF | abnormal SMN1 copy numbers | 19922137 |
254 | Amyotrophic Lateral Sclerosis | human | SMN2 | RF | 22187232 | |
257 | Amyotrophic Lateral Sclerosis | human | SOD1 | RF | Expression of N19S-SOD1, an SOD1 Mutant | 16035108 |
257 | Amyotrophic lateral sclerosis | human | SOD1 | RF | 24591609 | |
261 | Amyotrophic Lateral Sclerosis | human | SPG4 | RF | 16009903 | |
262 | Amyotrophic lateral sclerosis | human | SQSTM1 | RF | 22972638 | |
268 | Amyotrophic lateral sclerosis | human | STX12 | RF | 27455347 | |
272 | Amyotrophic lateral sclerosis | human | SUN3, HUS1 | RF | 25023141 | |
274 | Amyotrophic lateral sclerosis | human | TARDBP | RF | 25023141 | |
284 | Amyotrophic lateral sclerosis | human | TIAM1 | RF | 25023141 | |
284 | Amyotrophic Lateral Sclerosis | human | TIAM1 | RF | 20801718 | |
293 | Amyotrophic lateral sclerosis | human | TREM2 | RF | 24535663 | |
300 | Amyotrophic Lateral Sclerosis | human | UNC12A | RF | 22118904 | |
301 | Amyotrophic lateral sclerosis | human | UNC13A | RF | especially in Caucasian and European subjects | 31201598 |
301 | Amyotrophic Lateral Sclerosis | human | UNC13A | RF | 22118904 | |
302 | Amyotrophic lateral sclerosis | mouse | VAPB | RF | 23446633 | |
302 | Amyotrophic lateral sclerosis | zebrafish | VAPB | RF | 23446633 | |
306 | Amyotrophic lateral sclerosis | human | WDR49 | RF | 27455347 | |
307 | Amyotrophic lateral sclerosis | human | ZSCAN5B | RF | 27455347 | |
308 | Amyotrophic lateral sclerosis | human | 20% continuous increase of any agricultural land or specific crop type | RF | Total agricultural land | 28851431 |
308 | Amyotrophic lateral sclerosis | human | 20% continuous increase of any agricultural land or specific crop type | RF | Orchards | 28851431 |
308 | Amyotrophic lateral sclerosis | human | 20% continuous increase of any agricultural land or specific crop type | RF | Olive groves | 28851431 |
311 | Amyotrophic Lateral Sclerosis | human | A high intake of carbohydrate | RF | 17852010 | |
319 | Amyotrophic lateral sclerosis | rat | Age | RF | 30873018 | |
320 | Amyotrophic Lateral Sclerosis | human | Age at cessation of smoking | RF | 16963407 | |
321 | Amyotrophic lateral sclerosis | human | Age at first trauma leading to functional disability | RF | <35 years | 29063790 |
321 | Amyotrophic lateral sclerosis | human | Age at first trauma leading to functional disability | RF | 35–54 years | 29063790 |
321 | Amyotrophic lateral sclerosis | human | Age at first trauma leading to functional disability | RF | 35–54 years | 29063790 |
326 | Amyotrophic lateral sclerosis | human | Age of sport activity onset | PF | 24706338 | |
326 | Amyotrophic lateral sclerosis | human | Age of sport activity onset | PF | Significant adjusted OR | 24706338 |
326 | Amyotrophic lateral sclerosis | human | Age of sport activity onset | PF | 24706338 | |
328 | Amyotrophic Lateral Sclerosis | human | Agricultural chemicals | RF | 20012543 | |
329 | Amyotrophic lateral sclerosis | human | Agricultural chemicals (pesticides) | RF | 29681882 | |
330 | Amyotrophic Lateral Sclerosis | human | agricultural work | RF | 15995797 | |
331 | Amyotrophic lateral sclerosis | human | Air Force | RF | Adjusted for matching factors and socioeconomic status (SES) | 26583610 |
332 | Amyotrophic lateral sclerosis | human | Air pollution | RF | the nitrogen oxides NO2 and NOx | 29483062 |
332 | Amyotrophic Lateral Sclerosis | human | Air pollution | RF | Air Pollution Exposure( NOx concentrations) | 29989551 |
332 | Amyotrophic Lateral Sclerosis | human | Air pollution | RF | Air Pollution Exposure(NO2) | 29989551 |
332 | Amyotrophic Lateral Sclerosis | human | Air pollution | RF | Air Pollution Exposure(PM2.5) | 29989551 |
335 | Amyotrophic lateral sclerosis | human | Amateur sport activity | PF | 24706338 | |
338 | Amyotrophic lateral sclerosis | human | an IQR increase of CO | RF | 30622072 | |
339 | Amyotrophic lateral sclerosis | human | an IQR increase of PM10 | RF | 30622072 | |
340 | Amyotrophic lateral sclerosis | human | an IQR increase of PM2.5 | RF | 30622072 | |
341 | Amyotrophic lateral sclerosis | human | an IQR increase of SO2 | RF | 30622072 | |
344 | Amyotrophic lateral sclerosis | human | Military work | RF | Adjusted for matching factors and socioeconomic status (SES) | 26583610 |
346 | Amyotrophic lateral sclerosis | human | Arthritis | PF | 27065942 | |
350 | Amyotrophic lateral sclerosis | human | Average daily adulthood PA(Physical Activity) | RF | 26998882 | |
351 | Amyotrophic lateral sclerosis | human | Average daily PA(Physical Activity) in last 5–15 years | RF | 26998882 | |
352 | Amyotrophic lateral sclerosis | human | AVM(arteriovenous malformation) | RF | all | 26260352 |
352 | Amyotrophic lateral sclerosis | human | AVM(arteriovenous malformation) | RF | cerebral vessels | 26260352 |
353 | Amyotrophic lateral sclerosis | human | Bank tellers | RF | worked or were unemployed at 1991 Italian census, and were still resident in Turin at the beginning of 1996 | 28201634 |
359 | Amyotrophic lateral sclerosis | human | blood levels of Copper (μg/dL) | RF | Adjusted for age, gender and race/ethnicity. | 27085208 |
360 | Amyotrophic lateral sclerosis | human | blood levels of Manganese (μg/dL) | RF | Adjusted for age, gender and race/ethnicity. | 27085208 |
361 | Amyotrophic lateral sclerosis | human | blood levels of Selenium (μg/dL) | PF | Adjusted for age, gender and race/ethnicity. | 27085208 |
361 | Amyotrophic lateral sclerosis | human | blood levels of Selenium (μg/dL) | PF | Adjusted for age, gender and race/ethnicity. | 27085208 |
361 | Amyotrophic lateral sclerosis | human | blood levels of Selenium (μg/dL) | PF | Adjusted for age, gender and race/ethnicity. | 27085208 |
361 | Amyotrophic lateral sclerosis | human | blood levels of Selenium (μg/dL) | PF | Adjusted for age, gender and race/ethnicity. | 27085208 |
362 | Amyotrophic lateral sclerosis | human | blood levels of Zinc (μg/dL) | PF | Adjusted for age, gender and race/ethnicity. | 27085208 |
362 | Amyotrophic lateral sclerosis | human | blood levels of Zinc (μg/dL) | PF | Adjusted for age, gender and race/ethnicity. | 27085208 |
364 | Amyotrophic lateral sclerosis | human | BMI history | RF | OR controlled for age, sex, duration of school education, and smoking status | 28975435 |
364 | Amyotrophic lateral sclerosis | human | BMI history | RF | OR controlled for age, sex, duration of school education, and smoking status | 28975435 |
364 | Amyotrophic lateral sclerosis | human | BMI history | RF | OR controlled for age, sex, duration of school education, and smoking status | 28975435 |
364 | Amyotrophic lateral sclerosis | human | BMI history | PF | OR controlled for age, sex, duration of school education, and smoking status | 28975435 |
365 | Amyotrophic lateral sclerosis | human | BMI(Body Mass Index) | RF | Low BMI(Body Mass Index) | 31155341 |
366 | Amyotrophic lateral sclerosis | human | Boat, sail, or kayak | RF | residents of New England or the bordering New York region at the time of enrollment | 28122372 |
387 | Amyotrophic lateral sclerosis | mouse | Circadian rhythm dysfunction (CRD) | RF | Transgenic mice overexpressing human SOD1 were obtained from the Nanjing Biomedical Research Institute of Nanjing University | 29740382 |
392 | Amyotrophic lateral sclerosis | human | construction work | RF | 27124833 | |
392 | Amyotrophic Lateral Sclerosis | human | construction work | RF | 19750102 | |
393 | Amyotrophic lateral sclerosis | human | COPD(chronic obstructive pulmonary disease) | PF | 27065942 | |
397 | Amyotrophic lateral sclerosis | human | current proximity to any agricultural land or specific crop type within 100m from residence | RF | Total agricultural land | 28851431 |
398 | Amyotrophic lateral sclerosis | human | Defense NEC(Not Elsewhere Classified) | RF | Adjusted for matching factors and socioeconomic status (SES) | 26583610 |
401 | Amyotrophic lateral sclerosis | human | Diabetes | PF | Unadjusted | 26030836 |
401 | Amyotrophic lateral sclerosis | human | Diabetes | PF | Adjusted for socioeconomic status, prior chronic obstructive pulmonary disease, marital status, and residence at amyotrophic lateral sclerosis diagnosis. | 26030836 |
401 | Amyotrophic lateral sclerosis | human | Diabetes | PF | Adjusted for socioeconomic status, prior chronic obstructive pulmonary disease, marital status, and residence at amyotrophic lateral sclerosis diagnosis, with diabetes and obesity simultaneously included in the model. | 26030836 |
404 | Amyotrophic Lateral Sclerosis | human | Dietary habits:Cold cuts | RF | all cases | 19922125 |
404 | Amyotrophic Lateral Sclerosis | human | Dietary habits:Cold cuts | RF | Bulbar cases | 19922125 |
412 | Amyotrophic lateral sclerosis | human | Distance agricultural areas | RF | 100m |
29852480 |
414 | Amyotrophic lateral sclerosis | human | Drinking | RF | 31155341 | |
414 | Amyotrophic lateral sclerosis | human | Drinking | PF | 22791740 | |
419 | Amyotrophic lateral sclerosis | human | Duration of OCP(oral contraceptive) use (per year) | PF | female | 28835399 |
420 | Amyotrophic lateral sclerosis | human | Duration of physical activity | PF | 24706338 | |
420 | Amyotrophic lateral sclerosis | human | Duration of physical activity | PF | Significant adjusted OR | 24706338 |
420 | Amyotrophic lateral sclerosis | human | Duration of physical activity | PF | 24706338 | |
420 | Amyotrophic lateral sclerosis | human | Duration of physical activity | PF | 24706338 | |
420 | Amyotrophic lateral sclerosis | human | Duration of physical activity | PF | 24706338 | |
421 | Amyotrophic lateral sclerosis | human | Duration of sport activity | PF | 24706338 | |
421 | Amyotrophic lateral sclerosis | human | Duration of sport activity | PF | Significant adjusted OR | 24706338 |
421 | Amyotrophic lateral sclerosis | human | Duration of sport activity | PF | 24706338 | |
421 | Amyotrophic lateral sclerosis | human | Duration of sport activity | PF | 24706338 | |
425 | Amyotrophic lateral sclerosis | human | education | PF | Exposure in the last 30 years | 24979055 |
425 | Amyotrophic lateral sclerosis | human | education | PF | Exposure in the last 10 years | 24979055 |
425 | Amyotrophic lateral sclerosis | human | education | PF | Exposure in the period from 30 years ago to 10 years ago | 24979055 |
425 | Amyotrophic lateral sclerosis | human | education | PF | Continuous Exposure in the last 30 years | 24979055 |
425 | Amyotrophic Lateral Sclerosis | human | education | RF | Elementary school(Crude OR) | 17923612 |
425 | Amyotrophic lateral sclerosis | human | education | PF | Exposure Ever Happened in Entire Occupational History | 27159543 |
425 | Amyotrophic lateral sclerosis | human | education | PF | Exposure Ever Happened in Last 10 years | 27159543 |
425 | Amyotrophic lateral sclerosis | human | education | PF | Exposure Ever Happened 10-30 years Ago | 27159543 |
425 | Amyotrophic lateral sclerosis | human | education | PF | Exposure Ever Happened >30 years Ago | 27159543 |
425 | Amyotrophic Lateral Sclerosis | human | education | RF | 31011473 | |
425 | Amyotrophic lateral sclerosis | human | education | PF | Longer duration of education | 31155341 |
426 | Amyotrophic lateral sclerosis | human | Electric current injuries | RF | 27124833 | |
426 | Amyotrophic lateral sclerosis | human | Electric current injuries | RF | 29681882 | |
430 | Amyotrophic lateral sclerosis | human | Environmental toxins | RF | organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs) and brominated flame retardants (BFRs) | 27231185 |
432 | Amyotrophic lateral sclerosis | human | Ever worked in US Armed Forces | RF | Exposure Ever Happened 10-30 years Ago | 27159543 |
438 | Amyotrophic lateral sclerosis | human | Exposure to Lead | RF | residents of New England or the bordering New York region at the time of enrollment | 28122372 |
438 | Amyotrophic lateral sclerosis | human | Exposure to Lead | RF | residents of New England or the bordering New York region at the time of enrollment | 28122372 |
438 | Amyotrophic Lateral Sclerosis | human | Exposure to Lead | RF | 19750102 | |
438 | Amyotrophic Lateral Sclerosis | human | Exposure to Lead | RF | Ever had a job with lead exposure | 16909025 |
438 | Amyotrophic Lateral Sclerosis | human | Exposure to Lead | RF | Lifetime days of lead exposure:2,000+ | 16909025 |
444 | Amyotrophic lateral sclerosis | human | Exposure to Pesticide | RF | residents of New England or the bordering New York region at the time of enrollment | 28122372 |
444 | Amyotrophic lateral sclerosis | human | Exposure to Pesticide | RF | residents of New England or the bordering New York region at the time of enrollment | 28122372 |
444 | Amyotrophic Lateral Sclerosis | human | Exposure to Pesticide | RF | In a conditional logistic regression model | 20847462 |
446 | Amyotrophic lateral sclerosis | human | Exposure to Solvents | RF | residents of New England or the bordering New York region at the time of enrollment | 28122372 |
447 | Amyotrophic lateral sclerosis | human | Exposure to the highest quartiles of PM10 | RF | 30622072 | |
448 | Amyotrophic lateral sclerosis | human | Exposure to the highest quartiles of PM2.5 | RF | 30622072 | |
450 | Amyotrophic lateral sclerosis | human | Exposure to welding or soldering materials | RF | 27124833 | |
463 | Amyotrophic Lateral Sclerosis | human | Fire fighting occupations | RF | 20698805 | |
463 | Amyotrophic Lateral Sclerosis | human | Fire fighting occupations | RF | 20698805 | |
466 | Amyotrophic lateral sclerosis | human | Fractures | RF | all | 28316249 |
466 | Amyotrophic lateral sclerosis | human | Fractures | RF | osteoporotic | 28316249 |
466 | Amyotrophic lateral sclerosis | human | Fractures | RF | non-osteoporotic | 28316249 |
466 | Amyotrophic lateral sclerosis | human | Fractures | RF | traumatic | 28316249 |
466 | Amyotrophic lateral sclerosis | human | Fractures | RF | non-traumatic | 28316249 |
468 | Amyotrophic lateral sclerosis | human | Fungal infection | RF | 25892962 | |
469 | Amyotrophic lateral sclerosis | human | Gender | PF | 27065942 | |
470 | Amyotrophic lateral sclerosis | human | General practitioners | RF | worked or were unemployed at 1991 Italian census, and were still resident in Turin at the beginning of 1996 | 28201634 |
474 | Amyotrophic Lateral Sclerosis | human | having a past history of CS/SSM | RF | 17538776 | |
475 | Amyotrophic Lateral Sclerosis | human | having surgical treatment for CS/SSM | RF | 17538776 | |
478 | Amyotrophic Lateral Sclerosis | human | Head injury | RF | all cases | 19922125 |
478 | Amyotrophic Lateral Sclerosis | human | Head injury | RF | Bulbar cases | 19922125 |
478 | Amyotrophic Lateral Sclerosis | human | head injury | RF | Age at last injury (years)≥29 | 20129626 |
478 | Amyotrophic Lateral Sclerosis | human | head injury | RF | Years between last injury and reference date <=24 years | 20129626 |
478 | Amyotrophic Lateral Sclerosis | human | head injury | RF | Years between last injury and reference date <=15 years | 20129626 |
478 | Amyotrophic lateral sclerosis | human | head injury | RF | 31155341 | |
478 | Amyotrophic lateral sclerosis | human | head injury | RF | 2+ Trauma | 29063790 |
478 | Amyotrophic lateral sclerosis | human | head injury | RF | 25059395 | |
478 | Amyotrophic lateral sclerosis | human | head injury | RF | Head trauma leading to functional disability | 29063790 |
481 | Amyotrophic Lateral Sclerosis | human | heavy metals | RF | 6538286 | |
482 | Amyotrophic lateral sclerosis | human | Heavy metals (lead) | RF | 29681882 | |
486 | Amyotrophic Lateral Sclerosis | human | Herbicides/Pesticides | RF | with the total SALS group | 16946624 |
486 | Amyotrophic Lateral Sclerosis | human | Herbicides/Pesticides | RF | with male SALS patients | 16946624 |
503 | Amyotrophic lateral sclerosis | human | Hypercholesterolemia | PF | 25059395 | |
505 | Amyotrophic lateral sclerosis | human | Hyperlipidemia | PF | 27065942 | |
505 | Amyotrophic lateral sclerosis | human | Hyperlipidemia | RF | 30723964 | |
506 | Amyotrophic lateral sclerosis | human | Hypertension | PF | 31155341 | |
506 | Amyotrophic lateral sclerosis | human | Hypertension | PF | 27065942 | |
513 | Amyotrophic lateral sclerosis | human | Immunosuppressive drugs | PF | 25059395 | |
516 | Amyotrophic lateral sclerosis | human | industrial chemicals | RF | residents of New England or the bordering New York region at the time of enrollment | 28122372 |
516 | Amyotrophic lateral sclerosis | human | industrial chemicals | RF | residents of New England or the bordering New York region at the time of enrollment | 28122372 |
517 | Amyotrophic lateral sclerosis | human | Industry in accommodation or food services | PF | Exposure Ever Happened in Entire Occupational History | 27159543 |
517 | Amyotrophic lateral sclerosis | human | Industry in accommodation or food services | PF | Exposure Ever Happened >30 years Ago | 27159543 |
518 | Amyotrophic lateral sclerosis | human | Industry in health care or social assistance | PF | Exposure Ever Happened in Entire Occupational History | 27159543 |
519 | Amyotrophic lateral sclerosis | human | Industry in ublic administration | PF | Exposure Ever Happened in Entire Occupational History | 27159543 |
519 | Amyotrophic lateral sclerosis | human | Industry in ublic administration | PF | Exposure Ever Happened 10-30 years Ago | 27159543 |
524 | Amyotrophic Lateral Sclerosis | human | inhalation of BMAA, DAB, and other aerosolized cyanotoxins | RF | 19929742 | |
532 | Amyotrophic lateral sclerosis | human | Jobs as workers or farmers | RF | 31155341 | |
536 | Amyotrophic lateral sclerosis | human | Leisure time activity | RF | 23418211 | |
537 | Amyotrophic Lateral Sclerosis | human | Level of Herbicide/Pesticide Exposure | RF | the total SALS group | 16946624 |
537 | Amyotrophic Lateral Sclerosis | human | Level of Herbicide/Pesticide Exposure | RF | male SALS patients | 16946624 |
538 | Amyotrophic Lateral Sclerosis | human | Lifestyle factors | RF | Vigorous physical activity | 19342254 |
538 | Amyotrophic Lateral Sclerosis | human | Lifestyle factors | RF | self reported stress:high | 19342254 |
538 | Amyotrophic Lateral Sclerosis | human | Lifestyle factors | RF | Behavior pattern:Type A | 19342254 |
538 | Amyotrophic Lateral Sclerosis | human | Lifestyle factors | RF | Intake of green-yellow vegetables:Less | 19342254 |
538 | Amyotrophic Lateral Sclerosis | human | Lifestyle factors | RF | combination Type A behavior and Intake of green-yellow vegetables | 19342254 |
539 | Amyotrophic lateral sclerosis | human | Lifetime endogenous estrogen exposure (per year) | RF | 28835399 | |
541 | Amyotrophic Lateral Sclerosis | human | Living in rural environment | RF | Region of living more than 5 years before disease onset | 31011473 |
548 | Amyotrophic Lateral Sclerosis | human | Market-oriented skilled agricultural workers | RF | 20012543 | |
559 | Amyotrophic lateral sclerosis | human | medical service work | RF | 27124833 | |
560 | Amyotrophic lateral sclerosis | human | metals as Al, Cd, Hg, Mn and Pb | RF | 26671079 | |
344 | Amyotrophic lateral sclerosis | human | Military work | RF | born between 1945 and 1985 | 26468494 |
561 | Amyotrophic lateral sclerosis | human | Moderate trauma | RF | 29063790 | |
567 | Amyotrophic lateral sclerosis | human | Neurological | PF | 27065942 | |
569 | Amyotrophic lateral sclerosis | human | Non Vigorous Physical Activities | RF | 28413696 | |
577 | Amyotrophic lateral sclerosis | human | O2?tension | RF | low O2?tension | 30863976 |
315 | Amyotrophic lateral sclerosis | human | Obesity | PF | Unadjusted | 26030836 |
315 | Amyotrophic lateral sclerosis | human | Obesity | RF | 27065942 | |
578 | Amyotrophic Lateral Sclerosis | human | Occupation | RF | Craft and related trades workers(Crude OR) | 17923612 |
578 | Amyotrophic Lateral Sclerosis | human | Occupation | RF | primary industrial occupations(at disease onset) | 17538776 |
578 | Amyotrophic Lateral Sclerosis | human | Occupation | RF | secondary industrial occupations(at disease onset) | 17538776 |
578 | Amyotrophic Lateral Sclerosis | human | Occupation | PF | tertiary industrial occupations(at disease onset) | 17538776 |
578 | Amyotrophic lateral sclerosis | human | Occupation | RF | Occupations in contact with customer;sworked or were unemployed at 1991 Italian census, and were still resident in Turin at the beginning of 1996 | 28201634 |
578 | Amyotrophic lateral sclerosis | human | Occupation | RF | Primary occupation involves industrial chemicals;residents of New England or the bordering New York region at the time of enrollment | 28122372 |
578 | Amyotrophic lateral sclerosis | human | Occupation | RF | Primary occupation involves industrial chemicals;residents of New England or the bordering New York region at the time of enrollment | 28122372 |
579 | Amyotrophic lateral sclerosis | human | Occupational Exposure | PF | Occupational exposure to lead;Exposure Ever Happened in Entire Occupational History | 27159543 |
579 | Amyotrophic lateral sclerosis | human | Occupational Exposure | RF | Occupational exposure to pesticide;Exposure in the last 30 years | 24979055 |
579 | Amyotrophic lateral sclerosis | human | Occupational Exposure | RF | Occupational exposure to pesticide;Exposure Ever Happened in Entire Occupational History | 27159543 |
579 | Amyotrophic lateral sclerosis | human | Occupational Exposure | RF | Occupational exposure to pesticide;Exposure Ever Happened in Last 10 years | 27159543 |
579 | Amyotrophic lateral sclerosis | human | Occupational Exposure | RF | Occupational exposure to pesticide;Exposure Ever Happened 10-30 years Ago | 27159543 |
580 | Amyotrophic Lateral Sclerosis | human | Occupational history | RF | Occupational history:Building and construction sector of economic activity;Spinal cases | 19922125 |
580 | Amyotrophic Lateral Sclerosis | human | Occupational history | RF | Occupational history:Exposure to building and construction materials;Spinal cases | 19922125 |
580 | Amyotrophic Lateral Sclerosis | human | Occupational history | RF | Occupational history:Exposure to metals and metal fumes;Spinal cases | 19922125 |
581 | Amyotrophic lateral sclerosis | human | OCP(oral contraceptive) | PF | female | 28835399 |
582 | Amyotrophic lateral sclerosis | human | office work | RF | 27124833 | |
585 | Amyotrophic lateral sclerosis | human | Organic solvents | RF | 29681882 | |
586 | Amyotrophic lateral sclerosis | human | Organized sport activity | PF | 24706338 | |
586 | Amyotrophic lateral sclerosis | human | Organized sport activity | PF | Significant adjusted OR | 24706338 |
589 | Amyotrophic lateral sclerosis | human | overall muscle strength | RF | Low overall muscle strength | 29285652 |
590 | Amyotrophic Lateral Sclerosis | human | pack-years | RF | Bulbar cases | 19922125 |
593 | Amyotrophic lateral sclerosis | human | particulate matter | RF | PM2.5, PM10, and PMcoarse | 29483062 |
594 | Amyotrophic lateral sclerosis | human | particulate matter absorption | RF | PM2.5absorption | 29483062 |
604 | Amyotrophic lateral sclerosis | human | Physical activity | PF | 24706338 | |
604 | Amyotrophic lateral sclerosis | human | Physical activity | PF | Significant adjusted OR | 24706338 |
609 | Amyotrophic Lateral Sclerosis | human | playing professional football | RF | >5 years | 15634730 |
612 | Amyotrophic Lateral Sclerosis | human | precision metal workers | RF | 19750102 | |
622 | Amyotrophic lateral sclerosis | human | Professional sports | RF | 29681882 | |
628 | Amyotrophic lateral sclerosis | human | Race | RF | AA | 27065942 |
628 | Amyotrophic lateral sclerosis | human | Race | PF | other | 27065942 |
629 | Amyotrophic lateral sclerosis | human | Reading | PF | 31155341 | |
635 | Amyotrophic lateral sclerosis | human | Retirement or unemployment | PF | 31155341 | |
639 | Amyotrophic lateral sclerosis | human | SAH(subarachnoid haemorrhage) | RF | Transient ischaemic attack | 26260352 |
640 | Amyotrophic lateral sclerosis | human | Sales representatives | RF | worked or were unemployed at 1991 Italian census, and were still resident in Turin at the beginning of 1996 | 28201634 |
643 | Amyotrophic Lateral Sclerosis | human | selenium overexposure | RF | 21215776 | |
647 | Amyotrophic lateral sclerosis | human | Severe physical activities | PF | 31155341 | |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | current smokers | 22791740 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Ever smoker(Adjustment for education) | 10645818 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Current smoker(Adjustment for education) | 10645818 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Ever smoker(Adjustment for education and alcohol consumption) | 10645818 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Current smoker(Adjustment for education and alcohol consumption) | 10645818 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Duration of smoking ≥20 years(Adjustment for education) | 10645818 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Duration of smoking ≥20 years(Adjustment for education and alcohol consumption) | 10645818 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Cumulative pack-years<20 pack-years(Adjustment for education) | 10645818 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Cumulative pack-years≥20 pack-years(Adjustment for education) | 10645818 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Cumulative pack-years<20 pack-years(Adjustment for education and alcohol consumption) | 10645818 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Cumulative pack-years≥20 pack-years(Adjustment for education and alcohol consumption) | 10645818 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Combination recency and dose:Current, <20 pack years(Adjustment for education) | 10645818 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Combination recency and dose:Current, ≥20 pack-years(Adjustment for education and alcohol consumption) | 10645818 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Combination recency and dose:Current, <20 pack years(Adjustment for education) | 10645818 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Combination recency and dose:Current, ≥20 pack-years(Adjustment for education and alcohol consumption) | 10645818 |
652 | Amyotrophic lateral sclerosis | human | Smoking | RF | 31155341 | |
652 | Amyotrophic lateral sclerosis | human | Smoking | RF | 30786056 | |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Former smokers (Adjusted for Age) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Current smokers (Adjusted for Age) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Ever smokers (Adjusted for Age) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Pack-years smoked ≤20 (Adjusted for Age) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Pack-years smoked 21-35 (Adjusted for Age) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Pack-years smoked > 35 (Adjusted for Age) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Former smokers (Adjusted for Age, Body Mass Index, Physical Activity, and Education) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Ever smokers (Adjusted for Age, Body Mass Index, Physical Activity, and Education) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Pack-years smoked ≤20 (Adjusted for Age, Body Mass Index, Physical Activity, and Education) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Pack-years smoked 21-35 (Adjusted for Age, Body Mass Index, Physical Activity, and Education) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Pack-years smoked > 35 (Adjusted for Age, Body Mass Index, Physical Activity, and Education) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Former smokers (Adjusted for Age) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Ever smokers (Adjusted for Age) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Pack-years smoked 21-35 (Adjusted for Age) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Former smokers (Adjusted for Age, Body Mass Index, Physical Activity, and Education) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Ever smokers (Adjusted for Age, Body Mass Index, Physical Activity, and Education) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Pack-years smoked 21-35 (Adjusted for Age, Body Mass Index, Physical Activity, and Education) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Former smokers (Adjusted for Age) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Ever smokers (Adjusted for Age) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Pack-years smoked ≤20 (Adjusted for Age) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Pack-years smoked >35(Adjusted for Age) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Former smokers (Adjusted for Age, Body Mass Index, Physical Activity, and Education) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Ever smokers (Adjusted for Age, Body Mass Index, Physical Activity, and Education) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Pack-years smoked ≤20 (Adjusted for Age, Body Mass Index, Physical Activity, and Education) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Pack-years smoked >35(Adjusted for Age, Body Mass Index, Physical Activity, and Education) | 21320987 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Current(Crude OR) | 17923612 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Current(Adj. OR) | 17923612 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Current smokers | 19399866 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Time spent smoking≥30years | 19399866 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Bulbar cases | 19922125 |
652 | Amyotrophic Lateral Sclerosis | human | Smoking | RF | Bulbar cases | 19922125 |
657 | Amyotrophic Lateral Sclerosis | human | Solvents/Chemicals | RF | with the total SALS group | 16946624 |
657 | Amyotrophic Lateral Sclerosis | human | Solvents/Chemicals | RF | with male patients | 16946624 |
657 | Amyotrophic Lateral Sclerosis | human | Solvents/Chemicals | RF | with female patients | 16946624 |
659 | Amyotrophic Lateral Sclerosis | human | spatial locations | RF | 18573277 | |
660 | Amyotrophic lateral sclerosis | human | Sport activity | PF | 24706338 | |
663 | Amyotrophic lateral sclerosis | human | Stroke | RF | all | 26260352 |
663 | Amyotrophic lateral sclerosis | human | Stroke | RF | Haemorrhagic | 26260352 |
663 | Amyotrophic lateral sclerosis | human | Stroke | RF | Ischaemic | 26260352 |
663 | Amyotrophic lateral sclerosis | human | Stroke | RF | Unspecified | 26260352 |
668 | Amyotrophic lateral sclerosis | human | The widespread distribution of dioxins, PCBs and PAHs | RF | 28476168 | |
670 | Amyotrophic lateral sclerosis | human | Thyroid | PF | 27065942 | |
671 | Amyotrophic lateral sclerosis | human | toenail mercury levels | RF | 29314106 | |
674 | Amyotrophic Lateral Sclerosis | human | Toxin exposure | RF | 16963407 | |
676 | Amyotrophic lateral sclerosis | human | Trauma | RF | Previous trauma | 29681882 |
676 | Amyotrophic lateral sclerosis | human | Trauma | RF | 25059395 | |
676 | Amyotrophic Lateral Sclerosis | human | Trauma | RF | At least one traumatic event(All traumatic event) | 22537412 |
676 | Amyotrophic Lateral Sclerosis | human | Trauma | RF | Number of events reported:1(All traumatic event) | 22537412 |
676 | Amyotrophic Lateral Sclerosis | human | Trauma | RF | Number of events reported:3+(All traumatic event) | 22537412 |
676 | Amyotrophic Lateral Sclerosis | human | Trauma | RF | Worst traumatic event reported:Moderate(All traumatic event) | 22537412 |
676 | Amyotrophic Lateral Sclerosis | human | Trauma | RF | Worst traumatic event reported:Severe(All traumatic event) | 22537412 |
676 | Amyotrophic Lateral Sclerosis | human | Trauma | RF | Number of events requiring hospitalization:1(All traumatic event) | 22537412 |
676 | Amyotrophic Lateral Sclerosis | human | Trauma | RF | Number of events leading to disability:1(All traumatic event) | 22537412 |
676 | Amyotrophic Lateral Sclerosis | human | Trauma | RF | At least one traumatic event(Old traumatic events) | 22537412 |
676 | Amyotrophic Lateral Sclerosis | human | Trauma | RF | Number of events reported:2(Old traumatic events) | 22537412 |
676 | Amyotrophic Lateral Sclerosis | human | Trauma | RF | Number of events reported::3+(Old traumatic events) | 22537412 |
676 | Amyotrophic Lateral Sclerosis | human | Trauma | RF | Worst traumatic event reported:Moderate(Old traumatic events) | 22537412 |
676 | Amyotrophic Lateral Sclerosis | human | Trauma | RF | Worst traumatic event reported:Severe(Old traumatic events) | 22537412 |
676 | Amyotrophic Lateral Sclerosis | human | Trauma | RF | Number of events requiring hospitalization:2+(Old traumatic events) | 22537412 |
676 | Amyotrophic Lateral Sclerosis | human | Trauma | RF | Number of events leading to disability:2+(Old traumatic events) | 22537412 |
677 | Amyotrophic lateral sclerosis | human | Trauma leading to disability | RF | 29063790 | |
677 | Amyotrophic lateral sclerosis | human | Trauma leading to disability | RF | 29063790 | |
677 | Amyotrophic lateral sclerosis | human | Trauma leading to disability | RF | 1 Trauma | 29063790 |
677 | Amyotrophic lateral sclerosis | human | Trauma leading to disability | RF | 1 Trauma | 29063790 |
677 | Amyotrophic lateral sclerosis | human | Trauma leading to disability | RF | 2+ Trauma | 29063790 |
677 | Amyotrophic lateral sclerosis | human | Trauma leading to disability | RF | 2+ Trauma | 29063790 |
685 | Amyotrophic Lateral Sclerosis | human | Type of Herbicide/Pesticide Exposure | RF | Industrial exposure to herbicides/pesticides | 16946624 |
685 | Amyotrophic Lateral Sclerosis | human | Type of Herbicide/Pesticide Exposure | RF | Industrial exposure to herbicides/pesticides | 16946624 |
685 | Amyotrophic Lateral Sclerosis | human | Type of Herbicide/Pesticide Exposure | RF | industrial exposure being occasional | 16946624 |
685 | Amyotrophic Lateral Sclerosis | human | Type of Herbicide/Pesticide Exposure | RF | industrial exposure being occasional | 16946624 |
685 | Amyotrophic Lateral Sclerosis | human | Type of Herbicide/Pesticide Exposure | RF | industrial exposure being regular | 16946624 |
685 | Amyotrophic Lateral Sclerosis | human | Type of Herbicide/Pesticide Exposure | RF | industrial exposure being regular | 16946624 |
685 | Amyotrophic Lateral Sclerosis | human | Type of Herbicide/Pesticide Exposure | RF | Exposure to herbicides/pesticides through regular gardening | 16946624 |
685 | Amyotrophic Lateral Sclerosis | human | Type of Herbicide/Pesticide Exposure | RF | Exposure to herbicides/pesticides through regular gardening | 16946624 |
690 | Amyotrophic lateral sclerosis | human | Use of chemicals in job or hobby | RF | residents of New England or the bordering New York region at the time of enrollment | 28122372 |
690 | Amyotrophic lateral sclerosis | human | Use of chemicals in job or hobby | RF | residents of New England or the bordering New York region at the time of enrollment | 28122372 |
692 | Amyotrophic lateral sclerosis | human | Use of statins | PF | 25059395 | |
693 | Amyotrophic lateral sclerosis | human | Using fertilizer to treat gardens | RF | Exposure in the period from 30 years ago to 10 years ago | 24979055 |
700 | Amyotrophic lateral sclerosis | human | Water-Ski | RF | residents of New England or the bordering New York region at the time of enrollment | 28122372 |
703 | Amyotrophic lateral sclerosis | human | Work | PF | 24706338 | |
703 | Amyotrophic lateral sclerosis | human | Work | PF | Significant adjusted OR | 24706338 |
704 | Amyotrophic lateral sclerosis | human | Work & Sport | PF | 24706338 | |
704 | Amyotrophic lateral sclerosis | human | Work & Sport | PF | Significant adjusted OR | 24706338 |
712 | Amyotrophic lateral sclerosis | human | high amounts of PC(phycocyanin concentration) exposure | RF | 28470570 | |
717 | Amyotrophic lateral sclerosis | human | Aerosolization of cyanobacteria | RF | 23246360 | |
718 | Amyotrophic lateral sclerosis | mice | age-related decreases in ADAR2(adenosine deaminase acting on RNA 2) activity | RF | 22916266 | |
726 | Amyotrophic Lateral Sclerosis | human | APOE(protein) | RF | 11940705 | |
731 | Amyotrophic Lateral Sclerosis | human | Ataxin-2 intermediate-length polyglutamine expansions | RF | 21292779 | |
750 | Amyotrophic lateral sclerosis | human | decreased SOD1 stability and increased protein aggregation | RF | 28558143 | |
756 | Amyotrophic lateral sclerosis | human | dysregulation modulation of proteasome activity | RF | 24450587 | |
761 | Amyotrophic lateral sclerosis | human | ER(endoplasmic reticulum) proteostasis imbalance | RF | 26869642 | |
763 | Amyotrophic Lateral Sclerosis | human | Expanded glutamine repeats of the ataxin-2 (ATXN2) protein | RF | CAG repeat length >26 | 21610160 |
764 | Amyotrophic Lateral Sclerosis | human | Expanded glutamine repeats of the ataxin-2 (ATXN3) protein | RF | CAG repeat length >30 | 21610160 |
771 | Amyotrophic lateral sclerosis | human | high HbA1c(Hemoglobin A1c) levels | RF | 28934974 | |
814 | Amyotrophic Lateral Sclerosis | human | mutations in neurofilaments | RF | 16084104 | |
816 | Amyotrophic lateral sclerosis | human | neuronal apoptosis inhibitory protein | RF | 29311650 | |
821 | Amyotrophic lateral sclerosis | human | perturbations of the ER proteostasis network | RF | 25913742 | |
834 | Amyotrophic Lateral Sclerosis | human | Serum Ferritin | RF | 19452011 | |
836 | Amyotrophic lateral sclerosis | human | Serum Retinol-Binding Protein 4 Concentration | PF | Controlled for age and sex. | 29482216 |
836 | Amyotrophic lateral sclerosis | human | Serum Retinol-Binding Protein 4 Concentration | PF | Controlled for age and sex. | 29482216 |
836 | Amyotrophic lateral sclerosis | human | Serum Retinol-Binding Protein 4 Concentration | PF | Also adjusted for educational attainment, smoking, occupational work intensity, and family history of amyotrophic lateral sclerosis. | 29482216 |
836 | Amyotrophic lateral sclerosis | human | Serum Retinol-Binding Protein 4 Concentration | PF | Also adjusted for educational attainment, smoking, occupational work intensity, and family history of amyotrophic lateral sclerosis. | 29482216 |
836 | Amyotrophic lateral sclerosis | human | Serum Retinol-Binding Protein 4 Concentration | PF | Controlled for age and sex and also adjusted for body mass index and self-reported diabetes. | 29482216 |
836 | Amyotrophic lateral sclerosis | human | Serum Retinol-Binding Protein 4 Concentration | PF | Controlled for age and sex and also adjusted for body mass index and self-reported diabetes. | 29482216 |
836 | Amyotrophic lateral sclerosis | human | Serum Retinol-Binding Protein 4 Concentration | PF | Adjusted for educational attainment, smoking, occupational work intensity, and family history of amyotrophic lateral sclerosis and also adjusted for estimated glomerular filtration rate. | 29482216 |
836 | Amyotrophic lateral sclerosis | human | Serum Retinol-Binding Protein 4 Concentration | PF | Adjusted for educational attainment, smoking, occupational work intensity, and family history of amyotrophic lateral sclerosis and also adjusted for estimated glomerular filtration rate. | 29482216 |
876 | Amyotrophic Lateral Sclerosis | Human | SNP(combination SNP1 and SNP2) | RF | The estimations using the proposed method (unadjusted estimates) | 19740415 |
876 | Amyotrophic Lateral Sclerosis | Human | SNP(combination SNP1 and SNP2) | RF | The estimations using the proposed method (adjusted estimates) | 19740415 |
877 | Amyotrophic Lateral Sclerosis | Human | SNP(combination SNP1 and SNP3) | RF | The estimations using the proposed method (unadjusted estimates) | 19740415 |
877 | Amyotrophic Lateral Sclerosis | Human | SNP(combination SNP1 and SNP3) | RF | The estimations using the proposed method (adjusted estimates) | 19740415 |
191 | Amyotrophic Lateral Sclerosis | Human | MTHFR(T677T/A1298A) | RF | 22385294 | |
878 | Amyotrophic Lateral Sclerosis | Human | SMN1(one or three copies of SMN1 gene were pooled) | RF | 16931506 | |
879 | Amyotrophic Lateral Sclerosis | Human | combination of multiple genetic and environmental factors | RF | 18421219 | |
880 | Amyotrophic Lateral Sclerosis | Human | high intakes of carbohydrate and low intakes of fat and some kinds of fatty acids(when combined) | RF | 17852010 | |
881 | Amyotrophic Lateral Sclerosis | Human | Multivariate analysis (with covariates age, smoking, education, and occupation) | RF | 17923612 | |
882 | Amyotrophic Lateral Sclerosis | Human | Lifestyle factors(combination Type A behavior and Intake of green-yellow vegetables) | RF | 19342254 | |
880 | Amyotrophic Lateral Sclerosis | human | high intakes of carbohydrate and low intakes of fat and some kinds of fatty acids(when combined) | RF | 17852010 | |
891 | Amyotrophic lateral sclerosis | human | joint contribution of genetics and environmental exposures | RF | 28355414 | |
881 | Amyotrophic Lateral Sclerosis | human | Multivariate analysis (with covariates age, smoking, education, and occupation) | RF | 17923612 | |
178 | Amyotrophic lateral sclerosis | human | MFSD8 | RF | 32485802 | |
44 | Amyotrophic lateral sclerosis | human | C9orf72 | RF | 33177243 | |
44 | Amyotrophic lateral sclerosis | human | C9orf72 | RF | 33177243 | |
906 | Amyotrophic lateral sclerosis | human | CACNA1H | RF | 33177243 | |
914 | Amyotrophic lateral sclerosis | human | LRP10 | RF | rare, pathogenic variants in LRP10 | 33006184 |
916 | Amyotrophic lateral sclerosis | human | SPG7 mutations | RF | 33138082 | |
919 | Amyotrophic lateral sclerosis | human | intermediate-length alleles when present in both alleles | RF | Carriership of two intermediate-length alleles was associated with ALS, when the longer allele was ≥ 17 repeats | 33021140 |
919 | Amyotrophic lateral sclerosis | human | intermediate-length alleles when present in both alleles | RF | Carriership of two intermediate-length alleles was associated with ALS, when the longer allele was ≥ 21 repeats | 33021140 |
924 | Amyotrophic lateral sclerosis | human | high-density lipoprotein cholesterol [HDL-C] | RF | Higher levels of HDL-C | 32172343 |
951 | Amyotrophic lateral sclerosis | human | lead exposure | RF | environmental/occupational | 31578652 |
333 | Amyotrophic lateral sclerosis | human | alcohol consumption | RF | 32196748 | |
952 | Amyotrophic lateral sclerosis | human | head trauma | RF | 32019087 | |
953 | Amyotrophic lateral sclerosis | human | electric shock | RF | 32019087 | |
954 | Amyotrophic lateral sclerosis | human | use of private wells for drinking water | RF | 32019087 | |
955 | Amyotrophic lateral sclerosis | human | use of herbicides during gardening | RF | 32019087 | |
956 | Amyotrophic lateral sclerosis | human | overall fish consumption | PF | 32019087 | |
957 | Amyotrophic lateral sclerosis | human | history of occupation in the agricultural sector | RF | 32331298 | |
957 | Amyotrophic lateral sclerosis | human | history of occupation in the agricultural sector | RF | 32331298 | |
958 | Amyotrophic lateral sclerosis | human | occupational exposure to Solvents(thinners) | RF | 32331298 | |
959 | Amyotrophic lateral sclerosis | human | occupational exposure to Solvents(paint removers) | RF | 32331298 | |
960 | Amyotrophic lateral sclerosis | human | occupational exposure to electromagnetic fields | RF | 32331298 | |
961 | Amyotrophic lateral sclerosis | human | environmental exposure to electromagnetic fields | RF | 32331298 | |
962 | Amyotrophic lateral sclerosis | human | exposure to pesticides | RF | Occupational but not environmental exposure,particularly fungicides | 32331298 |
439 | Amyotrophic lateral sclerosis | human | exposure to metals | RF | particularly mercur yand selenium | 32331298 |
438 | Amyotrophic lateral sclerosis | human | Exposure to Lead | RF | 32331298 | |
963 | Amyotrophic lateral sclerosis | human | antidiabetics | PF | 32097525 | |
692 | Amyotrophic lateral sclerosis | human | Use of statins | RF | 32097525 | |
429 | Amyotrophic lateral sclerosis | human | environmental exposure to cadmium | RF | 33068316 | |
429 | Amyotrophic lateral sclerosis | human | environmental exposure to cadmium | RF | 33068316 | |
438 | Amyotrophic lateral sclerosis | human | Exposure to Lead | RF | 33068316 | |
438 | Amyotrophic lateral sclerosis | human | Exposure to Lead | RF | 33068316 | |
964 | Amyotrophic lateral sclerosis | human | Zinc | PF | 33068316 | |
964 | Amyotrophic lateral sclerosis | human | Zinc | PF | 33068316 | |
663 | Amyotrophic lateral sclerosis | human | stroke | RF | 32266542 | |
965 | Amyotrophic lateral sclerosis | human | lower BMI | RF | 32266542 | |
966 | Amyotrophic lateral sclerosis | human | regular physical activity | RF | 32266542 | |
967 | Amyotrophic lateral sclerosis | human | gut microbiota | RF/PF | butyrate-producing bacteria are less abundant in the gastrointestinal tracts of people with ALS (PALS) | 33135936 |
676 | Amyotrophic lateral sclerosis | human | trauma | RF | 33130429 | |
968 | Amyotrophic lateral sclerosis | human | solvents | RF | 33130429 | |
969 | Amyotrophic lateral sclerosis | human | diesel/CVD interaction | RF | 33130429 | |
970 | Amyotrophic lateral sclerosis | human | trauma/solvents interaction | PF | 33130429 | |
968 | Amyotrophic lateral sclerosis | human | solvents | RF | 33130429 | |
676 | Amyotrophic lateral sclerosis | human | trauma | RF | 33130429 | |
438 | Amyotrophic lateral sclerosis | human | Exposure to Lead | RF | 33130429 | |
971 | Amyotrophic lateral sclerosis | human | CVD | RF | 33130429 | |
972 | Amyotrophic lateral sclerosis | human | lead/solvents interaction | PF | 33130429 | |
973 | Amyotrophic lateral sclerosis | human | Vitamin A | RF | higher serum Vitamin A | 32625160 |
974 | Amyotrophic lateral sclerosis | human | Vitamin B2 | PF | higher serum Vitamin B2 | 32625160 |
975 | Amyotrophic lateral sclerosis | human | Vitamin B9 | PF | higher serum Vitamin B9 | 32625160 |
277 | Amyotrophic lateral sclerosis | human | Vitamin C | PF | higher serum Vitamin C | 32625160 |
848 | Amyotrophic lateral sclerosis | human | Vitamin E | RF | higher serum Vitamin E | 32625160 |
976 | Amyotrophic lateral sclerosis | human | Exposure to extremely low frequency magnetic fields (ELF-MF) | RF | 32946420 | |
952 | Amyotrophic lateral sclerosis | human | Head trauma | RF | with significantly greater effects for injuries occurring 10 or more years prior to symptom onset | 33006184 |
977 | Amyotrophic lateral sclerosis | human | severe electrical burns | RF | 33006184 | |
978 | Amyotrophic lateral sclerosis | human | Hobbies involving lead | RF | Exposures to lead 20 or more years prior to diagnosis had larger effect sizes compared to those occurring more recently. | 33006184 |
979 | Amyotrophic lateral sclerosis | human | Physicians | RF | 32687038 |
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