Bovine Spongiform Encephalopathy

Bovine spongiform encephalopathy (BSE), commonly known as mad cow disease, is an incurable and invariably fatal neurodegenerative disease of cattle.[2] Symptoms include abnormal behavior, trouble walking, and weight loss.[1] Later in the course of the disease, the cow becomes unable to function normally.[1] There is conflicting information about the time between infection and onset of symptoms.

In 2002, the World Health Organization (WHO) suggested it to be approximately four to five years.[2] Time from onset of symptoms to death is generally weeks to months.[2] Spread to humans is believed to result in variant Creutzfeldt–Jakob disease (vCJD).[3] As of 2018, a total of 231 cases of vCJD had been reported globally.[5]


[1]Casalone C, Hope J (2018). "Atypical and classic bovine spongiform encephalopathy". Human Prion Diseases. Handbook of Clinical Neurology. Vol. 153. Elsevier. pp. 121–134. doi:10.1016/B978-0-444-63945-5.00007-6. ISBN 9780444639455. PMID 29887132
[2]"Bovine spongiform encephalopathy". WHO. November 2002. Archived from the original on 18 December 2012. Retrieved 27 October 2018.
[3]"About BSE BSE (Bovine Spongiform Encephalopathy) Prion Diseases". CDC. 2 October 2018. Retrieved 26 October 2018.
[4]"Control Measures BSE (Bovine Spongiform Encephalopathy) Prion Diseases". CDC. 2 October 2018. Retrieved 27 October 2018.
[5]"BSE in North America BSE (Bovine Spongiform Encephalopathy) Prion Diseases". CDC. 2 October 2018. Retrieved 26 October 2018.

The search result for the NDD Category "Bovine Spongiform Encephalopathy"
A total of 10 results found based on your keywords
RF_ID Disease Name Species RF_Name Association Phase Condition Year PMID
4148 Bovine Spongiform Encephalopathy Cattle Keeping livestock other than cattle RF Diagnosis 2006 16930273
4146 Bovine Spongiform Encephalopathy Cattle Herd size RF Diagnosis 2007 17097171
4147 Bovine Spongiform Encephalopathy Cattle Herd size RF Diagnosis 2007 17097171
4145 Bovine Spongiform Encephalopathy Cattle Proprietary milk replacer used RF Diagnosis 2006 16617042
4144 Bovine Spongiform Encephalopathy Cattle Proprietary concentrate feed used RF Diagnosis 2006 16617042
4143 Bovine Spongiform Encephalopathy Cattle Use of milk replacers RF Diagnosis 2006 16930273
4142 Bovine Spongiform Encephalopathy Cattle Purchase of feedstuffs for poultry RF Diagnosis 2007 17425937
4141 Bovine Spongiform Encephalopathy Cattle Consumption of milk replacer RF Diagnosis 2007 17425937
4139 Bovine Spongiform Encephalopathy Cattle Proprietary concentrates consumed RF Diagnosis 2007 17425937
4140 Bovine Spongiform Encephalopathy Cattle Proprietary concentrates consumed RF Diagnosis 2007 17425937