Chronic Traumatic Encephalopathy

Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease caused by repeated head injuries.[1]

Symptoms may include behavioral problems, mood problems, and problems with thinking.[1] Symptoms typically do not begin until years after the injuries.[2] CTE often gets worse over time and can result in dementia.[2] It is unclear if the risk of suicide is altered.[1]


[1]Asken, BM; Sullan, MJ; DeKosky, ST; Jaffee, MS; Bauer, RM (1 October 2017). "Research Gaps and Controversies in Chronic Traumatic Encephalopathy: A Review". JAMA Neurology. 74 (10): 1255–1262. doi:10.1001/jamaneurol.2017.2396. PMID 28975240.
[2]Stein, TD; Alvarez, VE; McKee, AC (2014). "Chronic traumatic encephalopathy: a spectrum of neuropathological changes following repetitive brain trauma in athletes and military personnel". Alzheimer's Research & Therapy. 6 (1): 4. doi:10.1186/alzrt234. PMC 3979082. PMID 24423082.

The search result for the NDD Category "Chronic Traumatic Encephalopathy"
A total of 3 results found based on your keywords
RF_ID Disease Name Species RF_Name Association Condition PMID
436 Chronic Traumatic Encephalopathy human Exposure to contact sports RF 26518018
633 Chronic Traumatic Encephalopathy mice Repeated mild traumatic brain injury (r-mTBI) RF APOE3 and APOE4 specific effects following injury in a mouse model of r-mTBI 30711612
678 Chronic Traumatic Encephalopathy mice Traumatic brain injury (TBI) RF through the induction of tau hyperphosphorylation and aggregation 31317824
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