Chronic Traumatic Encephalopathy

Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease caused by repeated head injuries.[1]

Symptoms may include behavioral problems, mood problems, and problems with thinking.[1] Symptoms typically do not begin until years after the injuries.[2] CTE often gets worse over time and can result in dementia.[2] It is unclear if the risk of suicide is altered.[1]


[1]Asken, BM; Sullan, MJ; DeKosky, ST; Jaffee, MS; Bauer, RM (1 October 2017). "Research Gaps and Controversies in Chronic Traumatic Encephalopathy: A Review". JAMA Neurology. 74 (10): 1255–1262. doi:10.1001/jamaneurol.2017.2396. PMID 28975240.
[2]Stein, TD; Alvarez, VE; McKee, AC (2014). "Chronic traumatic encephalopathy: a spectrum of neuropathological changes following repetitive brain trauma in athletes and military personnel". Alzheimer's Research & Therapy. 6 (1): 4. doi:10.1186/alzrt234. PMC 3979082. PMID 24423082.

The search result for the NDD Category "Chronic Traumatic Encephalopathy"
A total of 6 results found based on your keywords
RF_ID Disease Name Species RF_Name Association Phase Condition Year PMID
2591 Chronic Traumatic Encephalopathy Human APOE?4 RF Diagnosis 2022 35759276
889 Chronic Traumatic Encephalopathy mice PUFAs (n-3 polyunsaturated fatty acids) PF Prognosis 2021 33913741
3792 Chronic Traumatic Encephalopathy Human Head injury RF Diagnosis 2021 33538222
3501 Chronic Traumatic Encephalopathy mice Repeated mild traumatic brain injury (r-mTBI) RF APOE3 and APOE4 specific effects following injury in a mouse model of r-mTBI 2019 30711612
3526 Chronic Traumatic Encephalopathy mice traumatic brain injury (TBI) RF through the induction of tau hyperphosphorylation and aggregation 2019 31317824
3430 Chronic Traumatic Encephalopathy Human Exposure to contact sports RF 2015 26518018
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