RF_ID |
Disease Name |
Species |
RF_Name |
Association |
Phase |
Condition |
Year |
PMID |
3826 |
Parkinson disease |
Human |
TMEM |
RF |
Diagnosis |
|
2021 |
33279243 |
3825 |
Parkinson disease |
Human |
TMEM |
RF |
Diagnosis |
|
2021 |
33279243 |
2168 |
Parkinson disease |
Human |
Rural living |
RF |
|
|
2001 |
11437458 |
2312 |
Parkinson disease |
Human |
Rural living |
RF |
|
|
1998 |
9778597 |
2167 |
Parkinson disease |
Human |
Rural living |
RF |
|
|
2001 |
11437458 |
2927 |
Parkinson disease |
Human |
Rural living |
RF |
|
|
2010 |
21059511 |
1300 |
Parkinson disease |
Human |
Residence |
PF |
Diagnosis |
|
1989 |
2710356 |
4290 |
Parkinson disease |
Human |
Occupational types |
RF |
Diagnosis |
|
1989 |
2710356 |
1301 |
Parkinson disease |
Human |
Occupational types |
PF |
Diagnosis |
|
1989 |
2710356 |
4291 |
Parkinson disease |
Human |
Occupational types |
RF |
Diagnosis |
|
1989 |
2710356 |
3840 |
Parkinson disease |
Human |
Leukocytosis |
RF |
|
|
2021 |
34058741 |
2014 |
Parkinson disease |
Human |
chronic obstructive pulmonary disease |
RF |
Prognosis |
|
2021 |
33219665 |
3974 |
Parkinson disease |
Human |
toxicant N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine quinone (6PPD-Q) |
RF |
Diagnosis |
|
2023 |
38147746 |
3973 |
Parkinson disease |
Human |
ganglion cell-inner plexiform layer complex (GCIPL) thickness |
RF |
Diagnosis |
|
2023 |
38104911 |
3972 |
Parkinson disease |
Human |
high mobility group box-1 (HMGB1) levels |
RF |
Diagnosis |
|
2023 |
38104911 |
1601 |
Parkinson disease |
Human |
adhesive capsulitis of the shoulder (ACS) |
RF |
Diagnosis |
|
2023 |
37428415 |
1664 |
Parkinson disease |
Human |
presence of cirrhosis |
RF |
Diagnosis |
infection with hepatitis C virus (HCV) |
2023 |
36872452 |
3971 |
Parkinson disease |
Human |
serum levels of selenoprotein P (SelP) |
RF |
Diagnosis |
|
2023 |
37995510 |
3970 |
Parkinson disease |
Human |
serum levels of Selenium (Se) |
RF |
Diagnosis |
|
2023 |
37995510 |
3969 |
Parkinson disease |
Human |
urine protein levels |
RF |
Diagnosis |
|
2023 |
38174461 |
3968 |
Parkinson disease |
Human |
creatinine levels |
RF |
Diagnosis |
|
2023 |
38174461 |
3967 |
Parkinson disease |
Human |
blood urea nitrogen levels |
RF |
Diagnosis |
|
2023 |
38174461 |
3070 |
Parkinson disease |
Human |
perivascular space (PVS) |
RF |
Diagnosis |
|
2023 |
36097211 |
2436 |
Parkinson disease |
Human |
paraventricular white matter hyperintensity (PVH) |
RF |
Diagnosis |
|
2023 |
36097211 |
2156 |
Parkinson disease |
Human |
cerebral small vessel disease (cSVD) |
RF |
Diagnosis |
|
2023 |
36097211 |
3966 |
Parkinson disease |
Human |
neutrophil/lymphocyte ratio |
RF |
Diagnosis |
|
2023 |
37159450 |
3965 |
Parkinson disease |
Human |
insulin-like growth factor 1 (IGF-1) |
RF |
Diagnosis |
|
2023 |
37159450 |
3962 |
Parkinson disease |
Human |
dysthyroidism |
RF |
Diagnosis |
|
2023 |
37294324 |
1506 |
Parkinson disease |
Human |
retinal age gap |
RF |
Diagnosis |
deep learning (DL) model trained on 19,200 fundus images of 11,052 chronic disease-free participants was used to predict retinal age |
2022 |
35352798 |
2528 |
Parkinson disease |
Human |
anticholinergic drugs |
RF |
Diagnosis |
|
2023 |
37357543 |
1668 |
Parkinson disease |
Human |
affective disorders |
RF |
Diagnosis |
incident PD over 16 years |
2022 |
35752216 |
1649 |
Parkinson disease |
Human |
affective disorders |
RF |
Diagnosis |
incident PD over 18 years |
2022 |
35752216 |
1652 |
Parkinson disease |
Human |
affective disorders |
RF |
Diagnosis |
incident PD over 17 years |
2022 |
35752216 |
1661 |
Parkinson disease |
Human |
affective disorders |
RF |
Diagnosis |
incident PD over 15 years |
2022 |
35752216 |
1667 |
Parkinson disease |
Human |
sleep disorders |
RF |
Diagnosis |
incident PD over 14 years |
2022 |
35752216 |
2517 |
Parkinson disease |
Human |
sleep disorders |
RF |
Diagnosis |
|
2022 |
36037514 |
406 |
Parkinson disease |
Human |
diet quality + physical activity |
PF |
Diagnosis |
|
2022 |
35984656 |
1829 |
Parkinson disease |
Human |
MIDN |
RF |
Diagnosis |
|
2023 |
36858566 |
925 |
Parkinson disease |
Human |
apolipoprotein A1 (Apo A1) |
PF |
Diagnosis |
|
2022 |
35723114 |
1709 |
Parkinson disease |
Human |
obsessive-compulsive disorder (OCD) |
RF |
Diagnosis |
|
2022 |
35980783 |
1691 |
Parkinson disease |
Human |
obsessive-compulsive disorder (OCD) |
RF |
Diagnosis |
|
2022 |
35980783 |
3952 |
Parkinson disease |
Human |
CD4 |
RF |
Diagnosis |
|
2022 |
36224715 |
3953 |
Parkinson disease |
Human |
CD4 |
RF |
Diagnosis |
|
2022 |
36224715 |
1710 |
Parkinson disease |
Human |
LRP1B |
RF |
Prognosis |
|
2023 |
36348503 |
764 |
Parkinson disease |
Human |
gout |
PF |
Diagnosis |
|
2022 |
35504516 |
2021 |
Parkinson disease |
Human |
DRD4 |
RF |
Diagnosis |
|
2022 |
35532648 |
2090 |
Parkinson disease |
Human |
DRD4 |
RF |
Diagnosis |
|
2022 |
35532648 |
1468 |
Parkinson disease |
Human |
antidepressants |
RF |
Diagnosis |
|
2022 |
35748105 |
3125 |
Parkinson disease |
Human |
Religiosity |
RF |
Diagnosis |
|
2023 |
35763200 |
2970 |
Parkinson disease |
Human |
tremor |
RF |
Diagnosis |
even 5 to 10 years before diagnosis |
2023 |
36342675 |
1948 |
Parkinson disease |
Human |
potential inflammatory component |
RF |
Diagnosis |
|
2023 |
36342675 |
2002 |
Parkinson disease |
Human |
gastrointestinal disorders |
RF |
Diagnosis |
|
2023 |
36342675 |
1994 |
Parkinson disease |
Human |
gastrointestinal disorders |
RF |
Diagnosis |
|
2023 |
36342675 |
2012 |
Parkinson disease |
Human |
skin disorders |
RF |
Diagnosis |
|
2023 |
36342675 |
1902 |
Parkinson disease |
Human |
skin disorders |
RF |
Diagnosis |
|
2023 |
36342675 |
2018 |
Parkinson disease |
Human |
changes of skin sensation |
RF |
Diagnosis |
|
2023 |
36342675 |
1950 |
Parkinson disease |
Human |
migraine |
RF |
Diagnosis |
|
2023 |
36342675 |
2968 |
Parkinson disease |
Human |
schizophrenia |
RF |
Diagnosis |
|
2023 |
36342675 |
2923 |
Parkinson disease |
Human |
schizophrenia |
RF |
Diagnosis |
even 5 to 10 years before diagnosis |
2023 |
36342675 |
2089 |
Parkinson disease |
Human |
sleep apnea |
RF |
Diagnosis |
|
2023 |
36342675 |
2150 |
Parkinson disease |
Human |
sleep apnea |
RF |
Diagnosis |
|
2023 |
37185062 |
1792 |
Parkinson disease |
Human |
sleep apnea |
RF |
Diagnosis |
|
2023 |
37269705 |
2525 |
Parkinson disease |
Human |
anosmia |
RF |
Diagnosis |
|
2023 |
36342675 |
921 |
Parkinson disease |
Human |
gut metabolites |
PF |
Diagnosis |
|
2022 |
35275534 |
919 |
Parkinson disease |
Human |
LRRK2 inhibition |
PF |
Treatment |
|
2022 |
35675433 |
1559 |
Parkinson disease |
Human |
grip strength |
RF |
Diagnosis |
|
2023 |
36912851 |
1578 |
Parkinson disease |
Human |
gait speed |
RF |
Diagnosis |
|
2023 |
36912851 |
1642 |
Parkinson disease |
Human |
Exhaustion |
RF |
Diagnosis |
|
2023 |
36912851 |
1263 |
Parkinson disease |
Human |
Physical activity (PA) |
PF |
Diagnosis |
|
2005 |
15728289 |
778 |
Parkinson disease |
Human |
Physical activity (PA) |
PF |
|
|
2020 |
32943485 |
419 |
Parkinson disease |
Human |
Physical activity (PA) |
PF |
|
|
2021 |
33435977 |
1275 |
Parkinson disease |
Human |
Physical activity (PA) |
PF |
Diagnosis |
Medium level of physical activity |
2015 |
25410713 |
788 |
Parkinson disease |
Human |
Physical activity (PA) |
PF |
Diagnosis |
|
2022 |
34649886 |
412 |
Parkinson disease |
Human |
Physical activity (PA) |
PF |
Diagnosis |
|
2022 |
35984656 |
1546 |
Parkinson disease |
Human |
Physical activity (PA) |
RF |
Diagnosis |
|
2023 |
36912851 |
777 |
Parkinson disease |
Human |
Physical activity (PA) |
PF |
Diagnosis |
|
2022 |
34649886 |
1375 |
Parkinson disease |
Human |
Radon exposure |
RF |
Diagnosis |
|
2023 |
36495187 |
1550 |
Parkinson disease |
Human |
Long sleep |
RF |
Diagnosis |
|
2022 |
35013056 |
1459 |
Parkinson disease |
Human |
anxiolytics |
RF |
Diagnosis |
|
2022 |
35748105 |
417 |
Parkinson disease |
Human |
Dietary patterns |
PF |
Diagnosis |
|
2022 |
35984656 |
767 |
Parkinson disease |
Human |
ABCA7 |
PF |
Diagnosis |
|
2022 |
35709878 |
3955 |
Parkinson disease |
Human |
ABCA7 |
RF |
Diagnosis |
|
2022 |
35709878 |
3110 |
Parkinson disease |
Human |
ABCB1 |
RF |
|
|
2014 |
24572589 |
2022 |
Parkinson disease |
Human |
ACE |
RF |
|
|
2002 |
12084438 |
3835 |
Parkinson disease |
Human |
ACE |
RF |
Prognosis |
|
2021 |
34945793 |
2023 |
Parkinson disease |
Human |
ACE |
RF |
|
|
2002 |
12084438 |
2889 |
Parkinson disease |
Human |
ADAM10 |
RF |
|
|
2021 |
33527480 |
2513 |
Parkinson disease |
Human |
ADH1B |
RF |
|
|
2019 |
30483881 |
3856 |
Parkinson disease |
Human |
ANKK1 |
RF |
|
|
2021 |
34151861 |
1679 |
Parkinson disease |
Human |
APOE |
RF |
Prognosis |
|
2023 |
36348503 |
2439 |
Parkinson disease |
Human |
APOE?4 |
RF |
|
|
2021 |
33057949 |
1952 |
Parkinson disease |
Human |
apolipoprotein E ( APOE) ε3 allele |
RF |
|
|
2019 |
30526202 |
809 |
Parkinson disease |
Human |
apolipoprotein E ( APOE) ε3 allele |
PF |
|
|
2019 |
30526202 |
3556 |
Parkinson disease |
Human |
Apolipoprotein E4 |
RF |
|
|
2005 |
15924299 |
3668 |
Parkinson disease |
Human |
ATP10B |
RF |
|
recessive loss of function mutations |
2020 |
32172343 |
3833 |
Parkinson disease |
Human |
BDNF |
RF |
Prognosis |
|
2021 |
34945793 |
2875 |
Parkinson disease |
Human |
C9orf72 |
RF |
|
|
2021 |
34440384 |
3051 |
Parkinson disease |
Human |
C9orf72 |
RF |
|
|
2013 |
23845100 |
2274 |
Parkinson disease |
Human |
C9orf72 |
RF |
|
|
2021 |
34440384 |
2281 |
Parkinson disease |
Human |
CARD15 |
RF |
|
|
2007 |
17174426 |
3210 |
Parkinson disease |
Human |
CCDC62/HIP1R |
RF |
|
|
2015 |
25818163 |
1854 |
Parkinson disease |
Human |
CCL2 |
RF |
|
|
2019 |
30761072 |
1863 |
Parkinson disease |
Human |
CCL2 |
RF |
|
|
2019 |
30761072 |
1985 |
Parkinson disease |
Human |
CD14 |
RF |
|
|
2006 |
16337421 |
3211 |
Parkinson disease |
rat |
CD157/BST1 |
RF |
|
|
2014 |
24795584 |
3954 |
Parkinson disease |
Human |
CD33 |
RF |
Diagnosis |
|
2023 |
37479176 |
901 |
Parkinson disease |
Human |
CD33 |
PF |
Diagnosis |
|
2021 |
33582190 |
926 |
Parkinson disease |
Human |
CD33 |
PF |
Diagnosis |
|
2023 |
37479176 |
3216 |
Parkinson disease |
Human |
CHCHD2 |
RF |
|
|
2016 |
27626775 |
2072 |
Parkinson disease |
Human |
Clusterin (CLU) |
RF |
Diagnosis |
|
2021 |
33295114 |
2228 |
Parkinson disease |
Human |
COMT |
RF |
|
|
1997 |
9503277 |
3790 |
Amyotrophic lateral sclerosis,Parkinson disease |
Human |
DAB1 |
RF |
Diagnosis |
|
2021 |
34707478 |
3832 |
Parkinson disease |
Human |
DBH |
RF |
Prognosis |
|
2021 |
34945793 |
1841 |
Parkinson disease |
Human |
DGCR8 |
RF |
|
|
2013 |
24018986 |
1842 |
Parkinson disease |
Human |
DGCR8 |
RF |
|
|
2013 |
24018986 |
2128 |
Parkinson disease |
Human |
DMRT2/SMARCA2 |
RF |
Diagnosis |
|
2021 |
33510632 |
3236 |
Parkinson disease |
Human |
DMT1 |
RF |
|
|
2015 |
25817364 |
2279 |
Parkinson disease |
Human |
DMT1 |
RF |
|
|
2011 |
21777657 |
2074 |
Parkinson disease |
Human |
DNA methylation (DNAm) CD56 |
RF |
Diagnosis |
|
2021 |
34768133 |
786 |
Parkinson disease |
Human |
DNA methylation (DNAm) EFEMP-1 |
PF |
Diagnosis |
|
2021 |
34768133 |
3109 |
Parkinson disease |
Human |
DNA Methylation cg10917602 site |
RF |
|
|
2016 |
27466229 |
892 |
Parkinson disease |
Human |
DOPA decarboxylase gene (DDC) |
PF |
Treatment |
|
2021 |
33051953 |
3834 |
Parkinson disease |
Human |
DRD2 |
RF |
Prognosis |
|
2021 |
34945793 |
2278 |
Parkinson disease |
Human |
DYRK1A |
RF |
|
especially for males |
2016 |
27546826 |
3239 |
Parkinson disease |
Human |
EMTP variation |
RF |
|
|
2019 |
30675927 |
2769 |
Parkinson disease |
Human |
Famliy history of familial Parkinson's disease |
RF |
|
|
2010 |
21059511 |
2444 |
Parkinson disease |
Human |
Famliy history of familial Parkinson's disease |
RF |
|
|
1996 |
8771062 |
3243 |
Parkinson disease |
Human |
FGF20 |
RF |
|
|
2004 |
15122513 |
1911 |
Parkinson disease |
Human |
FGF20 |
RF |
|
|
2014 |
24942208 |
3242 |
Parkinson disease |
Human |
FGF20 |
RF |
|
|
2012 |
22342445 |
3244 |
Parkinson disease |
Human |
FGF20 |
RF |
|
|
2004 |
15122513 |
3140 |
Parkinson disease |
Human |
FGF20 |
RF |
|
|
2015 |
26070653 |
3241 |
Parkinson disease |
Human |
FGF20 |
RF |
|
|
2015 |
26070653 |
3257 |
Parkinson disease |
Human |
GBA |
RF |
|
|
2019 |
30765263 |
1658 |
Parkinson disease |
Human |
GBA |
RF |
Prognosis |
|
2023 |
36348503 |
3099 |
Parkinson disease |
Human |
GBA |
RF |
|
|
2010 |
20131388 |
3254 |
Parkinson disease |
Human |
GBA |
RF |
|
Patients with early-onset were more likely to carry GBA mutations than those with late-onset |
2016 |
26868973 |
3836 |
Parkinson disease |
Human |
GBA |
RF |
Diagnosis |
|
2021 |
34951095 |
3256 |
Parkinson disease |
Human |
GBA |
RF |
|
|
2016 |
26000814 |
3096 |
Parkinson disease |
Human |
GBA |
RF |
|
|
2007 |
17702778 |
2767 |
Parkinson disease |
Human |
GBA |
RF |
|
|
2012 |
22387070 |
3258 |
Parkinson disease |
Human |
GBA |
RF |
|
|
2019 |
30765263 |
3063 |
Parkinson disease |
Human |
GBA |
RF |
|
|
2019 |
30765263 |
2944 |
Parkinson disease |
Human |
GBA |
RF |
|
|
2013 |
22812582 |
3255 |
Parkinson disease |
Human |
GBA |
RF |
|
strong risk factors in FPD, especially for autosomal dominant PD |
2014 |
24126159 |
2179 |
Parkinson disease |
Human |
GBA1 |
RF |
Diagnosis |
|
2022 |
37633302 |
2773 |
Parkinson disease |
Human |
GBA1 |
RF |
|
non-N370S mutations associated with Gaucher disease |
2013 |
22968580 |
1838 |
Parkinson disease |
Human |
GBA1 |
RF |
Diagnosis |
|
2022 |
37633302 |
898 |
Parkinson disease |
Human |
GCase gene therapy |
PF |
|
|
2021 |
34062940 |
3260 |
Parkinson disease |
Human |
GCH1 |
RF |
|
|
2017 |
27871051 |
1989 |
Parkinson disease |
Human |
GLIS1 |
RF |
|
|
2012 |
22759478 |
2737 |
Parkinson disease |
Human |
GP1BA |
RF |
|
|
2020 |
33021140 |
2213 |
Parkinson disease |
Human |
GP6 |
RF |
|
|
2020 |
33021140 |
3261 |
Parkinson disease |
Human |
GRIN2A |
RF |
|
taking creatine who also have high levels of caffeine intake |
2017 |
28320167 |
3262 |
Parkinson disease |
Human |
GRIN2A T allele |
RF |
|
taking creatine who also have high levels of caffeine intake |
2017 |
28320167 |
2905 |
Parkinson disease |
Human |
GSTM1 |
RF |
Diagnosis |
|
2021 |
32359946 |
2772 |
Parkinson disease |
Human |
GSTM1/T1 null genotypes |
RF |
Diagnosis |
|
2021 |
32359946 |
3032 |
Parkinson disease |
Human |
GSTT1 |
RF |
Diagnosis |
|
2021 |
32359946 |
3266 |
Parkinson disease |
Human |
HFE |
RF |
|
|
2006 |
16824219 |
684 |
Parkinson disease |
Human |
HFE |
PF |
|
Australian PD patients |
2002 |
12098643 |
3267 |
Parkinson disease |
Human |
HFE |
RF |
|
|
2006 |
16824219 |
683 |
Parkinson disease |
Human |
HFE |
PF |
|
Australian PD patients |
2002 |
12098643 |
3269 |
Parkinson disease |
Human |
HLA-DRA |
RF |
|
|
2014 |
25319953 |
3272 |
Parkinson disease |
Human |
IL-10 |
RF |
|
|
2012 |
22387064 |
3271 |
Parkinson disease |
Human |
IL-10 |
RF |
|
|
2012 |
21241672 |
3273 |
Parkinson disease |
Human |
IL-18 |
RF |
|
|
2012 |
21241672 |
1970 |
Parkinson disease |
Human |
ITGB5 |
RF |
|
|
2020 |
33021140 |
1719 |
Parkinson disease |
Human |
LRRK2 |
RF |
Diagnosis |
|
2023 |
35733392 |
3112 |
Parkinson disease |
Human |
LRRK2 |
RF |
|
reater frequency of the G2019S mutation in Jewish than in non-Jewish cases with Parkinson disease |
2006 |
17050822 |
2511 |
Parkinson disease |
Human |
LRRK2 |
RF |
|
especially in early-onset patients |
2015 |
26234753 |
2335 |
Parkinson disease |
Human |
LRRK2 |
RF |
|
|
2010 |
19854095 |
1941 |
Parkinson disease |
Human |
LRRK2 |
RF |
|
|
2012 |
23115130 |
2514 |
Parkinson disease |
Human |
LRRK2 |
RF |
|
|
2008 |
18716801 |
2548 |
Parkinson disease |
Human |
LRRK2 |
RF |
|
|
2006 |
16633828 |
3141 |
Parkinson disease |
Human |
LRRK2 |
RF |
|
|
2009 |
19699188 |
2888 |
Parkinson disease |
Human |
LRRK2 |
RF |
|
|
2009 |
19672984 |
805 |
Parkinson disease |
Human |
LRRK2 |
PF |
|
|
2012 |
23115130 |
3282 |
Parkinson disease |
Human |
LRRK2 |
RF |
|
|
2007 |
17960808 |
2504 |
Parkinson disease |
Human |
LRRK2 |
RF |
|
|
2007 |
17019612 |
2327 |
Parkinson disease |
Human |
LRRK2 |
RF |
|
|
2011 |
20629711 |
3872 |
Parkinson disease |
Human |
LRRK2 |
RF |
Diagnosis |
|
2021 |
33742109 |
2904 |
Parkinson disease |
Human |
LRRK2 |
RF |
|
|
2008 |
18201193 |
3281 |
Parkinson disease |
Human |
LRRK2 |
RF |
|
|
2011 |
21167764 |
2487 |
Parkinson disease |
Human |
LRRK2 |
RF |
|
|
2010 |
20673920 |
2981 |
Parkinson disease |
Human |
LRRK2 |
RF |
|
|
2013 |
23624603 |
3874 |
Parkinson disease |
Human |
LRRK2 |
RF |
Diagnosis |
|
2021 |
33574311 |
3855 |
Parkinson disease |
Human |
LRRK2 |
RF |
|
|
2021 |
34060004 |
2682 |
Parkinson disease |
Human |
LRRK2 |
RF |
|
|
2007 |
17314670 |
3284 |
Parkinson disease |
Human |
MAO |
RF |
|
|
1994 |
7913737 |
3283 |
Parkinson disease |
Human |
MAO |
RF |
|
|
1994 |
7913737 |
2079 |
Parkinson disease |
Human |
MAPT |
RF |
|
|
2005 |
15627775 |
3135 |
Parkinson disease |
Human |
MAPT |
RF |
|
|
2010 |
19912324 |
3286 |
Parkinson disease |
Human |
MC1R |
RF |
|
|
2009 |
19194882 |
3287 |
Parkinson disease |
Human |
MC1R |
RF |
|
|
2009 |
19194882 |
2840 |
Parkinson disease |
Human |
Monoamine oxidase-B (MAO-B) |
RF |
|
levodopa-induced dyskinesia(LID) |
2020 |
32346620 |
3844 |
Parkinson disease |
Human |
MTPAP |
RF |
|
|
2021 |
34394198 |
2639 |
Parkinson disease |
Human |
MUL1 |
RF |
Diagnosis |
|
2021 |
34946922 |
3298 |
Parkinson disease |
Human |
NOD2 |
RF |
|
associated with late-onset PD |
2013 |
23651603 |
3085 |
Parkinson disease |
Human |
Omi/HTRA2 |
RF |
|
|
2011 |
21338583 |
2953 |
Parkinson disease |
Human |
P2RY12 |
RF |
|
|
2020 |
33021140 |
3302 |
Parkinson disease |
Human |
P2X7 |
RF |
|
|
2013 |
23648388 |
3851 |
Parkinson disease |
Human |
PARK16 |
RF |
|
|
2021 |
34373950 |
3304 |
Parkinson disease |
Human |
PARK16 |
RF |
|
|
2016 |
27174169 |
2396 |
Parkinson disease |
Human |
PARK16 |
RF |
|
|
2011 |
21419001 |
728 |
Parkinson disease |
Human |
PARK16 |
PF |
|
|
2016 |
27174169 |
3305 |
Parkinson disease |
Human |
PARK2 |
RF |
|
|
2002 |
12056932 |
3307 |
Parkinson disease |
Human |
PARK2 |
RF |
|
|
2014 |
24729340 |
3306 |
Parkinson disease |
Human |
PARK2 |
RF |
|
|
2014 |
24729340 |
3308 |
Parkinson disease |
Human |
PARKIN |
RF |
|
|
2009 |
19636047 |
2387 |
Parkinson disease |
Human |
PARKIN |
RF |
|
|
1999 |
10511432 |
2386 |
Parkinson disease |
Human |
PARKIN |
RF |
|
|
1999 |
10511432 |
3309 |
Parkinson disease |
Human |
PD in first-degree relatives |
RF |
|
|
2000 |
11060508 |
3824 |
Parkinson disease |
Human |
PICALM mRNA expression |
RF |
Diagnosis |
|
2021 |
33386803 |
1869 |
Parkinson disease |
Human |
PINK1 |
RF |
|
|
2017 |
27807026 |
3310 |
Parkinson disease |
Human |
PINK1 |
RF |
|
|
2006 |
16969854 |
3312 |
Parkinson disease |
Human |
PLA2G6 |
RF |
|
|
2012 |
22213678 |
752 |
Parkinson disease |
Human |
PLEKHN1 |
PF |
Diagnosis |
|
2021 |
33510632 |
2836 |
Parkinson disease |
Human |
positive family history of PD |
RF |
|
|
1998 |
9778597 |
3871 |
Parkinson disease |
Human |
PRKN |
RF |
Diagnosis |
|
2021 |
33742109 |
3846 |
Parkinson disease |
Human |
PRKN |
RF |
|
|
2021 |
34434164 |
1784 |
Parkinson disease |
Human |
PRKN |
RF |
Diagnosis |
|
2021 |
33448283 |
3791 |
Amyotrophic lateral sclerosis,Parkinson disease |
Human |
PTPRT |
RF |
Diagnosis |
|
2021 |
34707478 |
3845 |
Parkinson disease |
Human |
RP11-305E6 |
RF |
|
|
2021 |
34394198 |
833 |
Parkinson disease |
Human |
Saitohin |
PF |
|
|
2015 |
25168738 |
3329 |
Parkinson disease |
Human |
Saitohin |
RF |
|
|
2015 |
25168738 |
2308 |
Parkinson disease |
Human |
SEMA5A |
RF |
|
|
2008 |
18950607 |
553 |
Parkinson disease |
Human |
SEMA5A |
PF |
|
|
2008 |
18950607 |
798 |
Parkinson disease |
Human |
SEMA5A |
PF |
|
|
2014 |
24706317 |
2307 |
Parkinson disease |
Human |
SEMA5A |
RF |
|
|
2008 |
18950607 |
552 |
Parkinson disease |
Human |
SEMA5A |
PF |
|
|
2008 |
18950607 |
1982 |
Parkinson disease |
Human |
SLC6A3 |
RF |
|
|
2014 |
24211691 |
1981 |
Parkinson disease |
Human |
SLC6A3 |
RF |
|
|
2014 |
24211691 |
2051 |
Parkinson disease |
Human |
SLC6A3 |
RF |
|
|
2014 |
24211691 |
770 |
Parkinson disease |
Human |
SLC6A3 |
PF |
|
|
2014 |
24211691 |
2050 |
Parkinson disease |
Human |
SLC6A3 |
RF |
|
|
2014 |
24211691 |
3334 |
Parkinson disease |
Human |
SMPD1 |
RF |
|
|
2015 |
26169695 |
1972 |
Parkinson disease |
Human |
SNCA |
RF |
|
|
2008 |
18404644 |
3129 |
Parkinson disease |
Human |
SNCA |
RF |
Diagnosis |
|
2021 |
33705925 |
2357 |
Parkinson disease |
Human |
SNCA |
RF |
|
|
2012 |
22349157 |
3838 |
Parkinson disease |
Human |
SNCA |
RF |
Diagnosis |
|
2021 |
33994928 |
3843 |
Parkinson disease |
Human |
SNCA |
RF |
|
|
2021 |
34394198 |
1971 |
Parkinson disease |
Human |
SNCA |
RF |
|
|
2008 |
18404644 |
708 |
Parkinson disease |
Human |
SNCA |
PF |
Diagnosis |
|
2021 |
34946922 |
3142 |
Parkinson disease |
Human |
SNCA |
RF |
|
|
2016 |
27699750 |
2218 |
Parkinson disease |
Human |
STK39 |
RF |
|
|
2015 |
26469904 |
3869 |
Parkinson disease |
Human |
SV2C |
RF |
Diagnosis |
|
2021 |
33760272 |
3828 |
Parkinson disease |
Human |
TENM4 |
RF |
Diagnosis |
|
2021 |
33185019 |
2310 |
Parkinson disease |
Human |
TFAM |
RF |
|
|
2010 |
19925850 |
3143 |
Parkinson disease |
Human |
TH |
RF |
|
|
2010 |
20809526 |
3839 |
Parkinson disease |
Human |
TOMM40 |
RF |
|
carriage of shorter '523' alleles |
2021 |
34234128 |
894 |
Parkinson disease |
Human |
TOMM40 |
PF |
|
carriage of longer '523' alleles |
2021 |
34234128 |
2693 |
Parkinson disease |
Human |
TREM2 |
RF |
|
|
2013 |
23800361 |
2173 |
Parkinson disease |
Human |
UCHL1 |
RF |
|
|
2012 |
22839974 |
2112 |
Parkinson disease |
Human |
VEGF |
RF |
|
|
2016 |
27481110 |
3852 |
Parkinson disease |
Human |
vitamin D Receptor(VDR) |
RF |
|
|
2021 |
34365149 |
3854 |
Parkinson disease |
Human |
vitamin D Receptor(VDR) |
RF |
|
|
2021 |
34365149 |
3853 |
Parkinson disease |
Human |
vitamin D Receptor(VDR) |
RF |
|
|
2021 |
34365149 |
3371 |
Parkinson disease |
Human |
VMAT2 |
RF |
|
|
2016 |
27137201 |
3870 |
Parkinson disease |
Human |
WBSCR17 |
RF |
Diagnosis |
|
2021 |
33760272 |
740 |
Parkinson disease |
Human |
ZFP64/TSHZ2 |
PF |
Diagnosis |
|
2021 |
33510632 |
2817 |
Parkinson disease |
Human |
family history of PD |
RF |
|
|
2020 |
32943485 |
4256 |
Parkinson disease |
Human |
Low education + High demands + Low control |
RF |
Diagnosis |
|
2018 |
30145813 |
4255 |
Parkinson disease |
Human |
Low education + High demands + High control |
RF |
Diagnosis |
|
2018 |
30145813 |
4254 |
Parkinson disease |
Human |
Low education + High job control |
RF |
Diagnosis |
|
2018 |
30145813 |
4253 |
Parkinson disease |
Human |
High education + High job demands |
RF |
Diagnosis |
|
2018 |
30145813 |
4252 |
Parkinson disease |
Human |
Tamoxifen + Breast Cancer |
RF |
Diagnosis |
|
2017 |
29285040 |
1260 |
Parkinson disease |
Human |
Caffeine + Never used PMH(Post-menopausal hormone) |
PF |
Diagnosis |
|
2017 |
28984617 |
4251 |
Parkinson disease |
Human |
Pesiticide+Ambient oxidative stressor exposure + APEX1 rs1130409 and OGG1 rs1052133 |
RF |
Diagnosis |
|
2017 |
28460087 |
1259 |
Parkinson disease |
Human |
UV-B and age |
PF |
Diagnosis |
An age-dependent quadratic association between UV-B and PD incidence |
2017 |
28033496 |
1258 |
Parkinson disease |
Human |
Dental Amalgam Fillings + Hyperlipidemia |
PF |
Diagnosis |
History of Dental Amalgam Fillings |
2016 |
27906991 |
1257 |
Parkinson disease |
Human |
Dental Amalgam Fillings + Diabetes |
PF |
Diagnosis |
History of Dental Amalgam Fillings |
2016 |
27906991 |
4250 |
Parkinson disease |
Human |
Lower levels of serum 25(OH)D and sunlight exposure |
RF |
Diagnosis |
|
2016 |
26959053 |
1256 |
Parkinson disease |
Human |
Coffee + Estrogen replacement therapy |
PF |
Diagnosis |
|
2004 |
26522888 |
4249 |
Parkinson disease |
Human |
OP(organophosphorus) + Variant ABCB1 genotypes at two polymorphic sites |
RF |
Diagnosis |
|
2015 |
26457621 |
4248 |
Parkinson disease |
Human |
Frequent OP + CT + TT genotype(NOS1 SNPs) |
RF |
Diagnosis |
Nitric oxide synthase (NOS) |
2016 |
26383258 |
1255 |
Parkinson disease |
Human |
High total cholesterol + statin |
PF |
Diagnosis |
|
2015 |
25639598 |
1254 |
Parkinson disease |
Human |
Caffeine + GRIN2A |
PF |
Diagnosis |
GRIN2A(glutamate receptor genotypes) |
2014 |
24915238 |
1253 |
Parkinson disease |
Human |
N-hexacosanol + fisetin |
PF |
Treatment |
|
2012 |
22846082 |
1252 |
Parkinson disease |
Human |
Physical activity + In the past 10 years |
PF |
Diagnosis |
|
2010 |
20660864 |
1251 |
Parkinson disease |
Human |
Physical activity + At age 35-39 |
PF |
Diagnosis |
|
2010 |
20660864 |
1250 |
Parkinson disease |
Human |
Smoking + NAT2 fast acetylators |
PF |
Diagnosis |
|
2010 |
20461808 |
1249 |
Parkinson disease |
Human |
Smoking + GSTP1*B*C |
PF |
Diagnosis |
|
2010 |
20461808 |
1248 |
Parkinson disease |
Human |
Smoking + GSTM1(Genotype) |
PF |
Diagnosis |
|
2010 |
20461808 |
4247 |
Parkinson disease |
Human |
Well-water contamination with propargite |
RF |
Diagnosis |
Water-soluble pesticides |
2009 |
20049211 |
4246 |
Parkinson disease |
Human |
Well-water contamination with chorpyrifos |
RF |
Diagnosis |
Water-soluble pesticides |
2009 |
20049211 |
4245 |
Parkinson disease |
Human |
Well-water contamination with methomyl |
RF |
Diagnosis |
Water-soluble pesticides |
2009 |
20049211 |
4244 |
Parkinson disease |
Human |
MDR1 variants + Pesticides |
RF |
Diagnosis |
|
2009 |
19184162 |
4243 |
Parkinson disease |
Human |
High nonheme iron and low vitamin C intakes |
RF |
Diagnosis |
|
2008 |
18945687 |
1247 |
Parkinson disease |
Human |
Smoking + Coffee + NSAIDS |
PF |
Diagnosis |
|
2008 |
17987647 |
4242 |
Parkinson disease |
Human |
MnSOD(T/C; C/C)+NQO1(C/T; T/T) + Pesticide exposure |
RF |
Diagnosis |
|
2007 |
17188257 |
4241 |
Parkinson disease |
Human |
NQO1(C/T; T/T) + Pesticide exposure |
RF |
Diagnosis |
|
2007 |
17188257 |
4240 |
Parkinson disease |
Human |
MnSOD(T/C; C/C) + Pesticide exposure |
RF |
Diagnosis |
|
2007 |
17188257 |
2786 |
Parkinson disease |
Human |
combine Traumatic brain injury and paraquat exposure |
RF |
|
|
2012 |
23150532 |
3654 |
Parkinson disease |
Human |
combined residential exposures(residential, non-occupational pesticide and heavy metal exposure) |
RF |
|
|
2010 |
19818671 |
1438 |
Parkinson disease |
Human |
Balance-Gait score AND levodopa equivalent dose (LED) |
RF |
Diagnosis |
|
2021 |
33505652 |
1448 |
Parkinson disease |
Human |
Balance-Gait score AND MDS-UPDRS motor complications score |
RF |
Diagnosis |
|
2021 |
33505652 |
774 |
Parkinson disease |
Human |
alpha-synuclein (NACP-Rep1) |
PF |
|
|
2005 |
15670652 |
1671 |
Parkinson disease |
Human |
calcium channel blocker |
RF |
Diagnosis |
|
2021 |
33647030 |
3569 |
Parkinson disease |
Human |
C-reactive protein (CRP) |
RF |
|
|
2019 |
31057478 |
3568 |
Parkinson disease |
Human |
C-reactive protein (CRP) |
RF |
|
|
2019 |
31057478 |
3570 |
Parkinson disease |
Human |
C-reactive protein (CRP) |
RF |
|
|
2019 |
31057478 |
3576 |
Parkinson disease |
Human |
disturbance of the plasmatic rate of Cu |
RF |
|
|
2013 |
23868039 |
1452 |
Parkinson disease |
Human |
levodopa equivalent dose (LED) |
RF |
Diagnosis |
|
2021 |
33505652 |
3864 |
Parkinson disease |
Human |
Lipoprotein-Associated Phospholipase A2(Lp-PLA2) |
RF |
Diagnosis |
|
2021 |
33958981 |
863 |
Parkinson disease |
Human |
lncRNA AK021630 |
PF |
|
|
2017 |
27151187 |
3601 |
Parkinson disease |
Human |
lncRNA AL049437 |
RF |
|
|
2017 |
27151187 |
3603 |
Parkinson disease |
Human |
Loss of aromatase cytochrome P450 function |
RF |
|
|
2008 |
18063054 |
3827 |
Parkinson disease |
Human |
molecular architecture of dopaminergic networks |
RF |
Diagnosis |
|
2021 |
33198485 |
893 |
Parkinson disease |
rat |
Naringenin (NAR) |
PF |
Treatment |
Paraquat (PQ); PQ-induced neurotoxicity and neurodegeneration |
2021 |
34655599 |
891 |
Parkinson disease |
Human |
Transferrin/Transferrin Receptor 2 (TfR2) |
PF |
Treatment |
significantly more pronounced in females rather than in males |
2021 |
33323945 |
2822 |
Parkinson disease |
Human |
White matter hyperintensities (WMH) |
RF |
Diagnosis |
|
2021 |
33782518 |
3830 |
Parkinson disease |
Human |
White matter hyperintensities (WMH) |
RF |
Prognosis |
higher levels of both WMH and indices of cerebrovascular disease pathologies in aging brains |
2021 |
34724033 |
3092 |
Parkinson disease |
Human |
White matter hyperintensities (WMH) |
RF |
Diagnosis |
|
2023 |
36097211 |
1898 |
Parkinson disease |
Human |
Age |
RF |
Diagnosis |
|
2023 |
37357543 |
3378 |
Parkinson disease |
rhesus monkey |
Age |
RF |
|
|
2011 |
21587290 |
3875 |
Parkinson disease |
Human |
Age |
RF |
Diagnosis |
|
2021 |
33515623 |
838 |
Parkinson disease |
Human |
Age |
PF |
|
GCH1 genotype T allele carries |
2017 |
27871051 |
2119 |
Parkinson disease |
Human |
Age |
RF |
|
|
2007 |
17884509 |
3146 |
Parkinson disease |
Human |
Gender |
RF |
|
|
2010 |
20111594 |
3964 |
Parkinson disease |
Human |
Male sex |
RF |
Diagnosis |
|
2023 |
37159450 |
3956 |
Parkinson disease |
Human |
older age |
RF |
Diagnosis |
|
2022 |
34758470 |
1635 |
Parkinson disease |
Human |
Ankylosing spondylitis (AS) |
RF |
|
NSAIDs used for AS control have some protective effects against PD |
2021 |
34602503 |
1731 |
Parkinson disease |
Human |
Ankylosing spondylitis (AS) |
RF |
|
NSAIDs used for AS control have some protective effects against PD |
2021 |
34602503 |
3863 |
Parkinson disease |
Human |
Appendicitis-like lesions |
RF |
Diagnosis |
|
2021 |
33876851 |
2895 |
Parkinson disease |
Human |
Bipolar disorder (BD) |
RF |
Diagnosis |
|
2023 |
36342675 |
3865 |
Parkinson disease |
Human |
Bipolar disorder (BD) |
RF |
Prognosis |
|
2021 |
33927683 |
2892 |
Parkinson disease |
Human |
Bipolar disorder (BD) |
RF |
Diagnosis |
even 5 to 10 years before diagnosis |
2023 |
36342675 |
2202 |
Parkinson disease |
Human |
Bipolar disorder (BD) |
RF |
Diagnosis |
|
2021 |
33075191 |
2374 |
Parkinson disease |
Human |
Carotid plaques |
RF |
|
|
2021 |
34033182 |
3823 |
Parkinson disease |
Human |
coronavirus disease 2019 (COVID-19) |
RF |
Prognosis |
PD patients with severe COVID-19 |
2021 |
33392827 |
3862 |
Parkinson disease |
Human |
coronavirus disease 2019 (COVID-19) |
RF |
Diagnosis |
|
2021 |
33942924 |
3034 |
Parkinson disease |
Human |
Diabetes |
RF |
|
|
2009 |
19467671 |
1702 |
Parkinson disease |
Human |
Diabetes |
RF |
Diagnosis |
infection with hepatitis C virus (HCV) |
2023 |
36872452 |
2344 |
Parkinson disease |
Human |
Diabetes |
RF |
|
|
2007 |
17251276 |
2277 |
Parkinson disease |
Human |
Diabetes |
RF |
Diagnosis |
|
2021 |
33492248 |
1967 |
Parkinson disease |
Human |
Diabetes |
RF |
Diagnosis |
|
2023 |
36342675 |
2024 |
Parkinson disease |
Human |
Diabetes |
RF |
Diagnosis |
|
2023 |
36342675 |
2094 |
Parkinson disease |
Human |
Diabetes |
RF |
Diagnosis |
|
2021 |
33492248 |
2343 |
Parkinson disease |
Human |
Diabetes |
RF |
|
|
2007 |
17251276 |
3035 |
Parkinson disease |
Human |
Diabetes |
RF |
|
|
2009 |
19467671 |
1503 |
Parkinson disease |
Human |
Diabetes |
RF |
Diagnosis |
|
2023 |
36692249 |
3963 |
Parkinson disease |
Human |
Diabetes |
RF |
Diagnosis |
|
2023 |
37294324 |
1846 |
Parkinson disease |
Human |
Drug-induced parkinsonism |
RF |
|
|
1998 |
9703296 |
1845 |
Parkinson disease |
Human |
Drug-induced parkinsonism |
RF |
|
|
1998 |
9703296 |
3961 |
Parkinson disease |
Human |
heart disease |
RF |
Diagnosis |
|
2022 |
34758470 |
2060 |
Parkinson disease |
Human |
Hepatitis C virus(HCV) |
RF |
|
|
2015 |
25608223 |
1998 |
Parkinson disease |
Human |
Hepatitis C virus(HCV) |
RF |
|
|
2016 |
26701382 |
1922 |
Parkinson disease |
Human |
Hepatitis C virus(HCV) |
RF |
|
|
2019 |
30710864 |
2037 |
Parkinson disease |
Human |
High blood pressure |
RF |
Diagnosis |
|
2021 |
32876524 |
1945 |
Parkinson disease |
Human |
infection |
RF |
|
|
2019 |
30632012 |
1874 |
Parkinson disease |
Human |
infection |
RF |
Diagnosis |
|
2022 |
36107840 |
2075 |
Parkinson disease |
Human |
infection |
RF |
Diagnosis |
|
2022 |
36107840 |
1464 |
Parkinson disease |
Human |
inflammatory bowel disease (IBD) |
RF |
|
|
2021 |
34499125 |
3479 |
Parkinson disease |
Human |
motor neuron disease (MND) |
RF |
|
|
2010 |
20669307 |
1650 |
Parkinson disease |
Human |
Prior stroke |
RF |
|
|
2019 |
31019987 |
3529 |
Parkinson disease |
Human |
type 1 Gaucher disease |
RF |
|
|
2010 |
20177787 |
3877 |
Parkinson disease |
Human |
Air pollution |
RF |
Diagnosis |
|
2021 |
33476876 |
3396 |
Parkinson disease |
Human |
chronic exposure to metals |
RF |
|
|
1997 |
9065542 |
3431 |
Parkinson disease |
Human |
exposure to hydrocarbon solvents |
RF |
|
|
2000 |
10980731 |
3433 |
Parkinson disease |
Human |
exposure to metals |
RF |
|
high reported industrial release of copper or manganese |
2010 |
20959505 |
3434 |
Parkinson disease |
Human |
exposure to metals |
RF |
|
high reported industrial release of copper or manganese |
2010 |
20959505 |
3436 |
Parkinson disease |
Human |
Exposure to neuroleptic drugs |
RF |
|
|
1999 |
10047927 |
2290 |
Parkinson disease |
Human |
exposure to Pb |
RF |
|
|
2006 |
17185278 |
3437 |
Parkinson disease |
rat |
Exposure to Pesticide |
RF |
|
|
2012 |
22563483 |
2569 |
Parkinson disease |
Human |
Exposure to Pesticide |
RF |
|
|
2020 |
32943485 |
2345 |
Parkinson disease |
Human |
Exposure to Pesticide |
RF |
|
|
2001 |
11437458 |
2454 |
Parkinson disease |
Human |
Exposure to Pesticide |
RF |
|
|
2010 |
21059511 |
3050 |
Parkinson disease |
Human |
exposure to trichloroethylene (TCE) |
RF |
|
|
2012 |
22083847 |
2078 |
Parkinson disease |
Human |
farming |
RF |
|
|
2001 |
11437458 |
2010 |
Parkinson disease |
Human |
farming |
RF |
|
|
2021 |
33435977 |
1453 |
Parkinson disease |
Human |
glyphosate exposure |
RF |
|
|
2019 |
30799335 |
3957 |
Parkinson disease |
Human |
heavy metals |
RF |
Diagnosis |
|
2022 |
34758470 |
3959 |
Parkinson disease |
Human |
living in an urban area |
RF |
Diagnosis |
|
2022 |
34758470 |
4289 |
Parkinson disease |
Human |
Occupational exposure |
RF |
Diagnosis |
|
1989 |
2710356 |
4288 |
Parkinson disease |
Human |
Occupational exposure |
RF |
Diagnosis |
|
1992 |
1620342 |
3485 |
Parkinson disease |
Human |
organophosphate (OP) or carbamate (CM) poisoning |
RF |
|
|
2017 |
27781262 |
2044 |
Parkinson disease |
Human |
paraquat exposure |
RF |
|
|
2012 |
23150532 |
3494 |
Parkinson disease |
Human |
Polychlorinated biphenyls (PCBs)exposure |
RF |
|
greater susceptibility of females. |
2012 |
22906799 |
3493 |
Parkinson disease |
Human |
Polychlorinated biphenyls (PCBs)exposure |
RF |
|
greater susceptibility of females. |
2012 |
22906799 |
3084 |
Parkinson disease |
Human |
Toxins other than pesticide |
RF |
|
|
2010 |
21059511 |
3528 |
Parkinson disease |
Human |
Trichloroethylene |
RF |
|
|
2008 |
18157908 |
3536 |
Parkinson disease |
Human |
welding |
RF |
|
|
2001 |
11148228 |
551 |
Parkinson disease |
Human |
anti-histamines |
PF |
|
|
2021 |
34494887 |
3399 |
Parkinson disease |
rat |
cinnarizine(a calcium antagonist that produces human parkinsonism) |
RF |
|
(a calcium antagonist that produces human parkinsonism) |
2005 |
15993444 |
435 |
Parkinson disease |
Human |
deep brain stimulation (DBS) treatment |
PF |
Prognosis |
|
2021 |
33278869 |
401 |
Parkinson disease |
Human |
Dipeptidyl peptidase-4 (DPP4) inhibitors |
PF |
Treatment |
|
2021 |
33895825 |
397 |
Parkinson disease |
Human |
Dipeptidyl peptidase-4 (DPP4) inhibitors |
PF |
Diagnosis |
in diabetic patients |
2023 |
38110464 |
1884 |
Parkinson disease |
Human |
duration of exposure to levodopa |
RF |
|
|
2013 |
23836370 |
1885 |
Parkinson disease |
Human |
duration of exposure to levodopa |
RF |
|
|
2013 |
23836370 |
3053 |
Parkinson disease |
Human |
general anesthesia |
RF |
|
|
2020 |
32943485 |
1882 |
Parkinson disease |
Human |
metoprolol |
RF |
|
|
2021 |
34598055 |
373 |
Parkinson disease |
Human |
Non-aspirin NSAIDS |
PF |
|
|
2021 |
33435977 |
400 |
Parkinson disease |
Human |
non-hydroxychloroquine immunosuppressant therapy |
PF |
|
Sj?gren syndrome (SS) |
2019 |
30946325 |
1777 |
Parkinson disease |
Human |
Proton pump inhibitors (PPIs) |
RF |
Diagnosis |
1-year lag period was applied between PPI exposure and PD development |
2023 |
38096177 |
2478 |
Parkinson disease |
Human |
statin use |
RF |
|
|
2021 |
34347020 |
897 |
Parkinson disease |
Human |
statin use |
PF |
|
|
2021 |
34275907 |
803 |
Parkinson disease |
Human |
β-agonists |
PF |
|
|
2021 |
34598055 |
1940 |
Parkinson disease |
Human |
β-antagonists |
RF |
|
|
2021 |
34598055 |
3948 |
Parkinson disease |
Human |
gut microbiota |
RF |
Diagnosis |
|
2022 |
35275534 |
3837 |
Parkinson disease |
Human |
gut microbiota |
RF |
Prognosis |
|
2021 |
34954497 |
1445 |
Parkinson disease |
Human |
MDS-UPDRS motor complications score |
RF |
Diagnosis |
|
2021 |
33505652 |
1662 |
Parkinson disease |
Human |
Suicide |
RF |
Prognosis |
|
2021 |
33326004 |
511 |
Parkinson disease |
Human |
Bone mineral density in femoral neck |
PF |
|
|
2021 |
33435977 |
644 |
Parkinson disease |
Human |
Bone mineral density in hip |
PF |
|
|
2021 |
33435977 |
526 |
Parkinson disease |
Human |
Bone mineral density in lumbar spine |
PF |
|
|
2021 |
33435977 |
1528 |
Parkinson disease |
Human |
dyslipidemia |
RF |
Diagnosis |
|
2023 |
36692249 |
525 |
Parkinson disease |
Human |
dyslipidemia |
PF |
Prognosis |
|
2021 |
33219665 |
3867 |
Parkinson disease |
Human |
elevated plasma Aβ40 levels |
RF |
Diagnosis |
|
2021 |
33782518 |
1567 |
Parkinson disease |
Human |
fasting plasma glucose (FPG) variability |
RF |
Diagnosis |
in the midlife population without diabetes |
2021 |
33039669 |
1939 |
Parkinson disease |
Human |
high fasting blood glucose |
RF |
Diagnosis |
|
2021 |
32876524 |
3589 |
Parkinson disease |
Human |
high serum lipid peroxidation rates |
RF |
|
|
1992 |
1641180 |
707 |
Parkinson disease |
Human |
High triglycerides |
PF |
Diagnosis |
|
2021 |
32876524 |
924 |
Parkinson disease |
Human |
high-density lipoprotein cholesterol (HDL-C) |
PF |
Diagnosis |
|
2022 |
35723114 |
1582 |
Parkinson disease |
Human |
Intelligence |
RF |
Diagnosis |
|
2021 |
33675447 |
900 |
Parkinson disease |
Human |
levels of total cholesterol, triglyceride, and uric acid |
PF |
Diagnosis |
|
2021 |
33905014 |
2017 |
Parkinson disease |
Human |
low high-density lipoprotein cholesterol |
RF |
Diagnosis |
|
2021 |
32876524 |
927 |
Parkinson disease |
Human |
low-density lipoprotein cholesterol (LDL-C) |
PF |
Diagnosis |
|
2023 |
38174461 |
3623 |
Parkinson disease |
Human |
Plasma Se or Fe elevation |
RF |
|
|
2013 |
24340079 |
865 |
Parkinson disease |
Human |
plasma Zn elevation |
PF |
|
|
2013 |
24340079 |
3130 |
Parkinson disease |
Human |
posterior division of the middle frontal gyrus (PMFG) |
RF |
|
|
2021 |
34276350 |
3625 |
Parkinson disease |
Human |
Reduced serum progranulin(GRN) level |
RF |
|
|
2013 |
23398167 |
1585 |
Parkinson disease |
Human |
resting heart rate (RHR) |
RF |
Diagnosis |
|
2021 |
33675447 |
372 |
Parkinson disease |
Human |
serum uric acid (UA) |
PF |
|
|
2021 |
33435977 |
3841 |
Parkinson disease |
Human |
serum uric acid (UA) |
RF |
|
Low concentrations of UA |
2021 |
33716713 |
561 |
Parkinson disease |
Human |
serum uric acid (UA) |
PF |
|
|
2021 |
33435977 |
610 |
Parkinson disease |
Human |
Serum vitamin B12 |
PF |
|
|
2021 |
33435977 |
499 |
Parkinson disease |
Human |
Serum vitamin D |
PF |
|
|
2021 |
33435977 |
3513 |
Parkinson disease |
Human |
SN hyperechogenicity (SN+) |
RF |
|
|
2013 |
23115051 |
922 |
Parkinson disease |
Human |
total cholesterol [TC] |
PF |
Diagnosis |
|
2022 |
35723114 |
923 |
Parkinson disease |
Human |
triglycerides [TG] |
PF |
Diagnosis |
|
2022 |
35723114 |
1450 |
Parkinson disease |
Human |
Balance-Gait score |
RF |
Diagnosis |
|
2021 |
33505652 |
1523 |
Parkinson disease |
Human |
chronic renal dysfunction |
RF |
|
Older adults |
2019 |
31021467 |
3401 |
Parkinson disease |
rat |
Circadian rhythm dysfunction (CRD) |
RF |
|
|
2017 |
27046648 |
3876 |
Parkinson disease |
Human |
constipation |
RF |
Prognosis |
PD patients with constipation have a higher incidence of depression |
2021 |
33564494 |
3404 |
Parkinson disease |
Human |
constipation |
RF |
|
the relative risk was higher for men than for women |
2016 |
27234704 |
1519 |
Parkinson disease |
Human |
dipstick-positive proteinuria |
RF |
|
Older adults |
2019 |
31021467 |
2322 |
Parkinson disease |
Human |
dyspepsia |
RF |
|
|
2020 |
32943485 |
3842 |
Parkinson disease |
Human |
Early morning off (EMO) |
RF |
Treatment |
people diagnosed with Parkinson's disease (PwPD) |
2021 |
34421569 |
2555 |
Parkinson disease |
Human |
epilepsy |
RF |
Diagnosis |
|
2023 |
36342675 |
3946 |
Parkinson disease |
Human |
Frailty |
RF |
Diagnosis |
|
2023 |
36912851 |
1542 |
Parkinson disease |
Human |
Frailty |
RF |
Diagnosis |
|
2023 |
36912851 |
3868 |
Parkinson disease |
Human |
Freezing of gait (FOG) |
RF |
Prognosis |
|
2021 |
33763009 |
1574 |
Parkinson disease |
Human |
Freezing of gait (FOG) |
RF |
Diagnosis |
|
2023 |
36166069 |
1909 |
Parkinson disease |
Human |
Hearing loss (HL) |
RF |
Diagnosis |
|
2023 |
36342675 |
1511 |
Parkinson disease |
Human |
Hypertension |
RF |
Diagnosis |
|
2023 |
36692249 |
1482 |
Parkinson disease |
Human |
Hypertension |
RF |
Diagnosis |
|
2021 |
32865628 |
1736 |
Parkinson disease |
Human |
Hypertension |
RF |
|
|
2021 |
32865628 |
2003 |
Parkinson disease |
Human |
Hypertension |
RF |
Diagnosis |
|
2023 |
36342675 |
382 |
Parkinson disease |
Human |
Hypertension |
PF |
|
|
2021 |
33435977 |
3468 |
Parkinson disease |
Human |
Hypertension |
RF |
|
|
1998 |
9778597 |
3960 |
Parkinson disease |
Human |
Idiopathic rapid eye movement sleep behaviour disorde |
RF |
Diagnosis |
|
2022 |
34758470 |
3469 |
Parkinson disease |
Human |
Idiopathic rapid eye movement sleep behaviour disorde |
RF |
|
|
2009 |
19843648 |
1466 |
Parkinson disease |
Human |
irritable bowel syndrome (IBS) |
RF |
Diagnosis |
hazard of PD was significantly higher in IBS patients only during the first two years of follow-up (aHR 2.96, 95% CI 1.78-4.92). |
2021 |
33646176 |
2731 |
Parkinson disease |
Human |
lobar Cerebral microbleeds (MBs) |
RF |
Diagnosis |
|
2021 |
33782518 |
3861 |
Parkinson disease |
Human |
long-standing cervical dystonia |
RF |
Diagnosis |
|
2021 |
34015516 |
1439 |
Parkinson disease |
Human |
MCI or dementia |
RF |
Diagnosis |
|
2021 |
33505652 |
1520 |
Parkinson disease |
Human |
metabolic syndrome (MetS) |
RF |
|
|
2021 |
34120914 |
1963 |
Parkinson disease |
Human |
metabolic syndrome (MetS) |
RF |
Diagnosis |
|
2021 |
32876524 |
1924 |
Parkinson disease |
Human |
non‐apnea sleep disorders (NSD) |
RF |
|
|
2017 |
28470725 |
1742 |
Parkinson disease |
Human |
olfactory dysfunction |
RF |
Prognosis |
|
2021 |
34014391 |
1555 |
Parkinson disease |
Human |
Osteoporosis |
RF |
Diagnosis |
|
2021 |
33236101 |
3489 |
Parkinson disease |
rat |
Peripheral inflammation |
RF |
|
|
2010 |
20584104 |
3498 |
Parkinson disease |
Human |
pretreatment motor dysfunction |
RF |
|
especially among older patients |
1997 |
9447497 |
3866 |
Parkinson disease |
Human |
probable rapid eye movement sleep behavior disorder(pRBD) |
RF |
Prognosis |
|
2021 |
33897604 |
3088 |
Parkinson disease |
Human |
probable rapid eye movement sleep behavior disorder(pRBD) |
RF |
Prognosis |
|
2021 |
34021898 |
3500 |
Parkinson disease |
Human |
psychiatric disorder |
RF |
|
particularly in people under age 50 |
2008 |
18080857 |
2937 |
Parkinson disease |
Human |
restless leg syndrome (RLS) |
RF |
Diagnosis |
|
2023 |
36342675 |
2887 |
Parkinson disease |
Human |
restless leg syndrome (RLS) |
RF |
Diagnosis |
even 5 to 10 years before diagnosis |
2023 |
36342675 |
3075 |
Parkinson disease |
Human |
restless leg syndrome (RLS) |
RF |
Prognosis |
|
2021 |
34955092 |
3505 |
Parkinson disease |
Human |
Sjogren syndrome (SS) |
RF |
|
|
2019 |
30946325 |
3520 |
Parkinson disease |
Human |
Stroke |
RF |
|
|
1998 |
9778597 |
1844 |
Parkinson disease |
Human |
Stroke |
RF |
|
|
2015 |
26576320 |
2562 |
Parkinson disease |
Human |
Stroke |
RF |
Prognosis |
|
2021 |
33219665 |
2581 |
Parkinson disease |
Human |
Stroke |
RF |
Prognosis |
|
2021 |
33219665 |
3690 |
Parkinson disease |
Human |
Vascular Inflammation:blood-brain barrier(BBB) |
RF |
|
|
2020 |
32733633 |
3829 |
Parkinson disease |
Human |
Vestibular dysfunction |
RF |
Diagnosis |
|
2021 |
32942935 |
1474 |
Parkinson disease |
Human |
visual impairment (VI) |
RF |
Diagnosis |
|
2021 |
34805812 |
1701 |
Parkinson disease |
Human |
Falls |
RF |
Diagnosis |
|
2021 |
33843696 |
1335 |
Parkinson disease |
Human |
falls and fractures |
RF |
Prognosis |
|
2021 |
33503061 |
2154 |
Parkinson disease |
Human |
Head injury |
RF |
|
|
2021 |
33435977 |
3450 |
Parkinson disease |
Human |
Head injury |
RF |
|
early in life |
2015 |
25603768 |
2124 |
Parkinson disease |
Human |
Head injury |
RF |
|
|
2017 |
28748275 |
3451 |
Parkinson disease |
Human |
Head injury |
RF |
|
|
2002 |
12140099 |
2209 |
Parkinson disease |
Human |
traumatic brain injury (TBI) |
RF |
Diagnosis |
|
2023 |
36342675 |
2473 |
Parkinson disease |
Human |
traumatic brain injury (TBI) |
RF |
|
|
2012 |
23150532 |
539 |
Parkinson disease |
Human |
Aspirin |
PF |
|
|
2021 |
34494887 |
1324 |
Parkinson disease |
Human |
β2-agonists |
PF |
Diagnosis |
|
2018 |
30311974 |
1323 |
Parkinson disease |
Human |
β2-agonists |
PF |
Diagnosis |
|
2018 |
30311974 |
1325 |
Parkinson disease |
Human |
β2-agonists |
PF |
Diagnosis |
|
2018 |
30311974 |
2237 |
Parkinson disease |
Human |
Propranolol |
RF |
|
|
2021 |
34598055 |
4373 |
Parkinson disease |
Human |
Propranolol |
RF |
Diagnosis |
|
2018 |
30311974 |
4372 |
Parkinson disease |
Human |
Propranolol |
RF |
Diagnosis |
|
2018 |
30311974 |
1322 |
Parkinson disease |
Human |
Dental Scaling |
PF |
Diagnosis |
Individuals aged 40-69 years, individuals without periodontal inflammatory disease (PID) showed a protective effect of dental scaling against PD development |
2018 |
30049978 |
1321 |
Parkinson disease |
Human |
Glitazone(GTZ) |
PF |
Diagnosis |
People with diabetes |
2017 |
28861893 |
4371 |
Parkinson disease |
Human |
Dental Amalgam Fillings |
RF |
Diagnosis |
History of Dental Amalgam Fillings |
2016 |
27906991 |
4370 |
Parkinson disease |
Human |
Methamphetamine/amphetamine abuse |
RF |
Diagnosis |
(ICD-9-CM 304.4, 305.7, 969.7, E854.2) |
2015 |
25479916 |
4369 |
Parkinson disease |
Human |
Zolpidem |
RF |
Diagnosis |
Zolpidem use in patients with sleep disturbance |
2014 |
25124550 |
4368 |
Parkinson disease |
Human |
Zolpidem |
RF |
Diagnosis |
Zolpidem use in patients with sleep disturbance |
2014 |
25124550 |
1320 |
Parkinson disease |
Human |
ARBs(angiotensin receptor blockers) |
PF |
Diagnosis |
Antihypertensive agents |
2014 |
24910980 |
1319 |
Parkinson disease |
Human |
ACEIs(angiotensin converting enzyme inhibitors) |
PF |
Diagnosis |
Antihypertensive agents |
2014 |
24910980 |
1318 |
Parkinson disease |
Human |
CCB(calcium channel blockers) |
PF |
Diagnosis |
Antihypertensive agents ;Centrally-acting dihydropyridine CCB use |
2014 |
24910980 |
4367 |
Parkinson disease |
Human |
Benzamides |
RF |
Diagnosis |
Neuroleptics |
2012 |
23019267 |
4366 |
Parkinson disease |
Human |
Phenothiazines |
RF |
Diagnosis |
Neuroleptics |
2012 |
23019267 |
4365 |
Parkinson disease |
Human |
Neuroleptics |
RF |
Diagnosis |
All Neuroleptics |
2012 |
23019267 |
4364 |
Parkinson disease |
Human |
Polypharmacy |
RF |
Diagnosis |
|
2011 |
21951955 |
4361 |
Parkinson disease |
Human |
Polypharmacy |
RF |
Diagnosis |
|
2011 |
21951955 |
4363 |
Parkinson disease |
Human |
Polypharmacy |
RF |
Diagnosis |
|
2011 |
21951955 |
4362 |
Parkinson disease |
Human |
Polypharmacy |
RF |
Diagnosis |
|
2011 |
21951955 |
1315 |
Parkinson disease |
Human |
Ibuprofen |
PF |
Diagnosis |
There was a dose-response relationship between tablets of ibuprofen taken per week and PD risk (p trend = 0.01). |
2011 |
21368281 |
1313 |
Parkinson disease |
Human |
L-type calcium channel blockers |
PF |
Diagnosis |
|
2010 |
20437557 |
1312 |
Parkinson disease |
Human |
Antihypertensives(Calcium channel blockers) |
PF |
Diagnosis |
|
2008 |
18256367 |
343 |
Parkinson disease |
Human |
NSAIDs |
Not Related |
Diagnosis |
|
2007 |
17851257 |
1314 |
Parkinson disease |
Human |
Statin |
PF |
Diagnosis |
Short-term (
2010 |
20629142 |
|
1788 |
Parkinson disease |
Human |
Statin |
RF |
Diagnosis |
hyperlipidemia |
2022 |
35276584 |
1316 |
Parkinson disease |
Human |
Statin |
PF |
Diagnosis |
|
2012 |
22410446 |
1774 |
Parkinson disease |
Human |
Statin |
RF |
Diagnosis |
hyperlipidemia |
2022 |
35276584 |
384 |
Parkinson disease |
Human |
Statin |
PF |
|
|
2021 |
33435977 |
1317 |
Parkinson disease |
Human |
Statin |
PF |
Diagnosis |
Statin treatment |
2013 |
24304212 |
4358 |
Parkinson disease |
Human |
Sunflowers |
RF |
Diagnosis |
Crop exposure |
2018 |
29136149 |
4357 |
Parkinson disease |
Human |
Wheat/Barley |
RF |
Diagnosis |
Crop exposure |
2018 |
29136149 |
4356 |
Parkinson disease |
Human |
Cattle |
RF |
Diagnosis |
Animal exposure |
2018 |
29136149 |
4355 |
Parkinson disease |
Human |
Vegetables |
RF |
Diagnosis |
Crop exposure |
2018 |
29136149 |
4354 |
Parkinson disease |
Human |
Fruit-growing |
RF |
Diagnosis |
Crop exposure |
2018 |
29136149 |
4352 |
Parkinson disease |
Human |
Rape |
RF |
Diagnosis |
Crop exposure |
2018 |
29136149 |
4351 |
Parkinson disease |
Human |
Beet |
RF |
Diagnosis |
Crop exposure |
2018 |
29136149 |
4350 |
Parkinson disease |
Human |
Peas |
RF |
Diagnosis |
Crop exposure |
2018 |
29136149 |
4349 |
Parkinson disease |
Human |
Corn |
RF |
Diagnosis |
Crop exposure |
2018 |
29136149 |
4348 |
Parkinson disease |
Human |
Poultry |
RF |
Diagnosis |
Animal exposure |
2018 |
29136149 |
4347 |
Parkinson disease |
Human |
Horse |
RF |
Diagnosis |
Animal exposure |
2018 |
29136149 |
4346 |
Parkinson disease |
Human |
Swine |
RF |
Diagnosis |
Animal exposure |
2018 |
29136149 |
4345 |
Parkinson disease |
Human |
Bulb cultivation |
RF |
Diagnosis |
|
2017 |
28704700 |
4343 |
Parkinson disease |
Human |
SO2 |
RF |
Prognosis |
A unit increase in 8-day moving average of concentrations was significantly associated with PD aggravation. |
2017 |
28300224 |
4342 |
Parkinson disease |
Human |
NO2 |
RF |
Prognosis |
A unit increase in 8-day moving average of concentrations was significantly associated with PD aggravation. |
2017 |
28300224 |
4340 |
Parkinson disease |
Human |
Organophosphate(OP) or Carbamate poisoning(CM) |
RF |
Diagnosis |
|
2017 |
27781262 |
4339 |
Parkinson disease |
Human |
CO |
RF |
Diagnosis |
|
2016 |
27614945 |
4344 |
Parkinson disease |
Human |
CO |
RF |
Prognosis |
A unit increase in 8-day moving average of concentrations was significantly associated with PD aggravation. |
2017 |
28300224 |
4338 |
Parkinson disease |
Human |
NOx |
RF |
Diagnosis |
|
2016 |
27614945 |
4337 |
Parkinson disease |
Human |
PM10 |
RF |
Diagnosis |
Among female non-smokers |
2016 |
27285422 |
4336 |
Parkinson disease |
Human |
PM2.5 |
RF |
Diagnosis |
Among female non-smokers |
2016 |
27285422 |
4341 |
Parkinson disease |
Human |
PM2.5 |
RF |
Prognosis |
A unit increase in 8-day moving average of concentrations was significantly associated with PD aggravation. |
2017 |
28300224 |
3951 |
Parkinson disease |
Human |
PM2.5 |
RF |
Diagnosis |
|
2023 |
37903644 |
4360 |
Parkinson disease |
Human |
PM2.5 |
RF |
Diagnosis |
|
2018 |
30124852 |
1310 |
Parkinson disease |
Human |
Sunlight exposure |
PF |
Diagnosis |
|
2016 |
26959053 |
4335 |
Parkinson disease |
Human |
Occupational complexity |
RF |
Diagnosis |
|
2015 |
26444091 |
3958 |
Parkinson disease |
Human |
Pesticide exposure |
RF |
Diagnosis |
|
2022 |
34758470 |
4334 |
Parkinson disease |
Human |
Pesticide exposure |
RF |
Diagnosis |
|
2015 |
26345784 |
4333 |
Parkinson disease |
Human |
Capital city |
RF |
Diagnosis |
|
2016 |
26151951 |
1309 |
Parkinson disease |
Human |
Artistic occupations |
PF |
Diagnosis |
|
2015 |
26138540 |
1311 |
Parkinson disease |
Human |
Artistic occupations |
PF |
Diagnosis |
Pooled odds ratios for PD across the Rotterdam and
Radboud studies |
2018 |
30007105 |
342 |
Parkinson disease |
Human |
Working night shifts |
Not Related |
Diagnosis |
|
2015 |
25950750 |
4331 |
Parkinson disease |
Human |
High complexity of work with people |
RF |
Diagnosis |
|
2014 |
25198429 |
4330 |
Parkinson disease |
Human |
High complexity of work with data |
RF |
Diagnosis |
|
2014 |
25198429 |
4329 |
Parkinson disease |
Human |
Chemical exposure |
RF |
Diagnosis |
|
2014 |
25097376 |
4328 |
Parkinson disease |
Human |
Exposure to anesthetic gases |
RF |
Diagnosis |
|
2013 |
24321326 |
4327 |
Parkinson disease |
Human |
Evening work |
RF |
Diagnosis |
|
2013 |
24125560 |
4326 |
Parkinson disease |
Human |
OP pesticides |
RF |
Diagnosis |
OP(organophosphorus ) |
2013 |
24057998 |
341 |
Parkinson disease |
Human |
Outdoor work |
Not Related |
Diagnosis |
|
2013 |
24044947 |
1308 |
Parkinson disease |
Human |
WBV(whole-body vibration ) |
PF |
Diagnosis |
|
2012 |
22798480 |
4325 |
Parkinson disease |
Human |
Trichloroethylene(TCE) |
RF |
Diagnosis |
Solvent exposures |
2012 |
22083847 |
1307 |
Parkinson disease |
Human |
Professional or technical occupation |
PF |
Diagnosis |
|
2011 |
21733194 |
4324 |
Parkinson disease |
Human |
Combined exposure to ziram, maneb, and paraquat |
RF |
Diagnosis |
|
2011 |
21505849 |
340 |
Parkinson disease |
Human |
Working outdoors |
Not Related |
Diagnosis |
Moderate outdoor work(Nursery or kindergarten teachers, station personnel, filling-station attendants, estate agents, firemen, policemen, miners and electricians) |
2011 |
20884793 |
1306 |
Parkinson disease |
Human |
Working outdoors |
PF |
Diagnosis |
Maximal outdoor work(Farmers, chimneysweeps, frogmen, smallholders, farmhands, farm workers, gardeners, foresters, well diggers and pavers) |
2011 |
20884793 |
1305 |
Parkinson disease |
Human |
Working outdoors |
PF |
Diagnosis |
Frequent outdoor work(Postmen, window cleaners, millers, shipbuilders, building painters, joiners, seamen and bricklayers) |
2011 |
20884793 |
1304 |
Parkinson disease |
Human |
Service-sector worker |
PF |
Diagnosis |
|
2010 |
20402575 |
4323 |
Parkinson disease |
Human |
Naphtha and its
derivates |
RF |
Diagnosis |
|
2010 |
20402575 |
4322 |
Parkinson disease |
Human |
Dyes |
RF |
Diagnosis |
|
2010 |
20402575 |
4320 |
Parkinson disease |
Human |
Gardening |
RF |
Diagnosis |
|
2010 |
20402575 |
4319 |
Parkinson disease |
Human |
Exposure to pesticides, herbicides and insecticides |
RF |
Diagnosis |
|
2010 |
20353703 |
4318 |
Parkinson disease |
Human |
Blue collar occupations |
RF |
Diagnosis |
|
2010 |
20353703 |
4313 |
Parkinson disease |
Human |
Occupational exposure to Pb |
RF |
Diagnosis |
μg/g(micrograms Pb storage per gram of bone) |
2006 |
17185278 |
4311 |
Parkinson disease |
Human |
History of heavy metal and toxin exposure |
RF |
Diagnosis |
|
2003 |
14607318 |
4308 |
Parkinson disease |
Human |
Plantation |
RF |
Diagnosis |
|
2002 |
12433267 |
4307 |
Parkinson disease |
Human |
Farming as an occupation |
RF |
Diagnosis |
|
2002 |
11903115 |
4306 |
Parkinson disease |
Human |
Work in construction |
RF |
Diagnosis |
|
2001 |
11383940 |
4300 |
Parkinson disease |
Human |
Insecticides |
RF |
Diagnosis |
|
1998 |
9595985 |
4321 |
Parkinson disease |
Human |
Insecticides |
RF |
Diagnosis |
|
2010 |
20402575 |
4299 |
Parkinson disease |
Human |
Herbicides |
RF |
Diagnosis |
|
1998 |
9595985 |
3848 |
Parkinson disease |
Human |
Herbicides |
RF |
|
|
2021 |
34421783 |
4298 |
Parkinson disease |
Human |
Farming as an occupation after age 18 |
RF |
Diagnosis |
|
1998 |
9595985 |
4305 |
Parkinson disease |
Human |
Iron-copper |
RF |
Diagnosis |
|
1999 |
10385887 |
4297 |
Parkinson disease |
Human |
Iron-copper |
RF |
Diagnosis |
|
1997 |
9065542 |
4304 |
Parkinson disease |
Human |
Lead-iron |
RF |
Diagnosis |
|
1999 |
10385887 |
4296 |
Parkinson disease |
Human |
Lead-iron |
RF |
Diagnosis |
|
1997 |
9065542 |
4295 |
Parkinson disease |
Human |
Lead-copper |
RF |
Diagnosis |
|
1997 |
9065542 |
4303 |
Parkinson disease |
Human |
Lead-copper |
RF |
Diagnosis |
|
1999 |
10385887 |
4294 |
Parkinson disease |
Human |
Manganese |
RF |
Diagnosis |
|
1997 |
9065542 |
4301 |
Parkinson disease |
Human |
Manganese |
RF |
Diagnosis |
|
1999 |
10385887 |
4302 |
Parkinson disease |
Human |
Copper |
RF |
Diagnosis |
|
1999 |
10385887 |
4293 |
Parkinson disease |
Human |
Copper |
RF |
Diagnosis |
|
1997 |
9065542 |
4310 |
Parkinson disease |
Human |
Pesticide |
RF |
Diagnosis |
|
2003 |
12956856 |
4292 |
Parkinson disease |
Human |
Pesticide |
RF |
Diagnosis |
|
1993 |
8414014 |
4315 |
Parkinson disease |
Human |
Pesticide |
RF |
Diagnosis |
Age≤59.8 years |
2008 |
18322262 |
4317 |
Parkinson disease |
Human |
Pesticide |
RF |
Diagnosis |
|
2009 |
19847896 |
4309 |
Parkinson disease |
Human |
Pesticide |
RF |
Diagnosis |
|
2003 |
12902626 |
4332 |
Parkinson disease |
Human |
Pesticide |
RF |
Diagnosis |
Pesticide exposure in farms that specialized in vineyards |
2015 |
25815770 |
4314 |
Parkinson disease |
Human |
Pesticide |
RF |
Diagnosis |
|
2007 |
17188257 |
4316 |
Parkinson disease |
Human |
Pesticide |
RF |
Diagnosis |
|
2008 |
18373838 |
1302 |
Parkinson disease |
Human |
Wheat growing |
PF |
Diagnosis |
|
1989 |
2710356 |
2722 |
Parkinson disease |
Human |
Metals |
RF |
|
|
2020 |
32943485 |
3847 |
Parkinson disease |
Human |
Pesticides |
RF |
|
|
2021 |
34421783 |
2732 |
Parkinson disease |
Human |
Pesticides |
RF |
|
|
2021 |
34494887 |
4312 |
Parkinson disease |
Human |
Pesticides |
RF |
Diagnosis |
|
2006 |
16802290 |
1303 |
Parkinson disease |
Human |
Pesticides |
PF |
Diagnosis |
|
2006 |
16773614 |
2084 |
Parkinson disease |
Human |
Pesticides |
RF |
|
|
2021 |
33435977 |
1587 |
Parkinson disease |
Human |
Pesticides |
RF |
Prognosis |
|
2021 |
33278869 |
1953 |
Parkinson disease |
Human |
Organic solvents |
RF |
|
|
2021 |
33435977 |
1299 |
Parkinson disease |
Human |
Lifetime exposure to estrogens |
PF |
Diagnosis |
|
2014 |
25179495 |
1298 |
Parkinson disease |
Human |
High estrogen oral contraceptives |
PF |
Diagnosis |
|
2014 |
24750445 |
4287 |
Parkinson disease |
Human |
Menopausal hormone |
RF |
Diagnosis |
|
2014 |
24352877 |
4286 |
Parkinson disease |
Human |
Oral contraceptives |
RF |
Diagnosis |
|
2011 |
21956541 |
1297 |
Parkinson disease |
Human |
Oral contraceptives |
PF |
Diagnosis |
|
2014 |
24352877 |
4283 |
Parkinson disease |
Human |
Postmenopausal use of estrogen alone + Women with a hysterectomy |
RF |
Diagnosis |
|
2005 |
16087902 |
4282 |
Parkinson disease |
Human |
Surgical menopause |
RF |
Diagnosis |
|
2004 |
15184606 |
4281 |
Parkinson disease |
Human |
Pregnancies |
RF |
Diagnosis |
|
2004 |
15184606 |
4280 |
Parkinson disease |
Human |
Age of mother at subject's birth |
RF |
Diagnosis |
The age of the mother at subject's birth was
signifcantly older in cases (27.4 years, SD 5.9)
than in controls (25.1 years, SD 5.8, P < 0.005). |
2002 |
11903115 |
4279 |
Parkinson disease |
Human |
Children |
RF |
Diagnosis |
|
2001 |
11359079 |
4284 |
Parkinson disease |
Human |
Children |
RF |
Diagnosis |
|
2007 |
17265462 |
4285 |
Parkinson disease |
Human |
Children |
RF |
Diagnosis |
|
2007 |
17265462 |
3138 |
Parkinson disease |
Human |
Adult nutrient intake |
RF |
|
|
1999 |
10661654 |
383 |
Parkinson disease |
Human |
Alcohol consumption |
PF |
|
|
2021 |
33435977 |
751 |
Parkinson disease |
Human |
Alcohol consumption |
PF |
Diagnosis |
|
2022 |
34649886 |
734 |
Parkinson disease |
Human |
Alcohol consumption |
PF |
Diagnosis |
|
2022 |
34649886 |
3392 |
Parkinson disease |
Human |
caffeine intake |
RF |
|
GRIN2A rs4998386 T allele;taking creatine who also have high levels of caffeine intake |
2017 |
28320167 |
579 |
Parkinson disease |
Human |
chimarr?o( Ilex paraguariensis , IP) |
PF |
Diagnosis |
|
2021 |
33776884 |
370 |
Parkinson disease |
Human |
Coffee consumption |
PF |
|
|
2021 |
33435977 |
375 |
Parkinson disease |
Human |
Coffee consumption |
PF |
|
|
2021 |
33435977 |
677 |
Parkinson disease |
Human |
Coffee consumption |
PF |
|
|
2020 |
32943485 |
369 |
Parkinson disease |
Human |
Coffee consumption |
PF |
|
|
2021 |
33435977 |
896 |
Parkinson disease |
Human |
Coffee consumption |
PF |
|
|
2021 |
34421783 |
377 |
Parkinson disease |
Human |
Coffee consumption |
PF |
|
|
2021 |
33435977 |
821 |
Parkinson disease |
Human |
Dietary Risk |
PF |
|
|
2019 |
30863359 |
3859 |
Parkinson disease |
Human |
Eating disorders (EDs) |
RF |
Prognosis |
especially for PD women and in patients with specific impulsive personality traits |
2021 |
34035366 |
2967 |
Parkinson disease |
Human |
Meat consumption |
RF |
|
|
2021 |
34494887 |
2521 |
Parkinson disease |
Human |
Meat consumption |
RF |
|
|
2021 |
34494887 |
3040 |
Parkinson disease |
Human |
oils |
RF |
|
|
2020 |
32943485 |
3521 |
Parkinson disease |
Human |
tea drinking |
RF |
|
|
2000 |
11060508 |
390 |
Parkinson disease |
Human |
Vitamin E dietary intake |
PF |
|
|
2021 |
33435977 |
3537 |
Parkinson disease |
Human |
well water ingestion |
RF |
|
|
2008 |
18464276 |
3539 |
Parkinson disease |
Human |
well water ingestion |
RF |
|
|
1998 |
9778597 |
3439 |
Parkinson disease |
Human |
well water ingestion |
RF |
|
|
1992 |
1584237 |
3538 |
Parkinson disease |
Human |
well water ingestion |
RF |
|
|
2002 |
12140099 |
1980 |
Parkinson disease |
Human |
well water ingestion |
RF |
|
|
2001 |
11437458 |
3689 |
Parkinson disease |
Human |
well water(containing heavy metals and nitrates) |
RF |
|
Consumption of well water containing heavy metals and nitrates in early life |
2020 |
32351250 |
1997 |
Parkinson disease |
Human |
Well-Water Consumption |
RF |
Diagnosis |
|
2021 |
34938078 |
2016 |
Parkinson disease |
Human |
Well-Water Consumption |
RF |
Diagnosis |
in hospital-based case-control studies |
2021 |
34938078 |
3849 |
Parkinson disease |
Human |
non-potable water |
RF |
|
|
2021 |
34421783 |
2210 |
Parkinson disease |
Human |
sleep quality |
RF |
Diagnosis |
|
2023 |
36342675 |
3857 |
Parkinson disease |
Human |
sleep quality |
RF |
|
periodic limb movements during sleep (PLMS) was the risk factor that influenced the objective sleep quality in PD patients with RLS |
2021 |
34177757 |
4359 |
Parkinson disease |
Human |
Tobacco |
RF |
Diagnosis |
Crop exposure |
2018 |
29136149 |
895 |
Parkinson disease |
Human |
tobacco |
PF |
|
|
2021 |
34421783 |
899 |
Parkinson disease |
Human |
Health Qigong exercises |
PF |
Prognosis |
|
2021 |
33953563 |
439 |
Parkinson disease |
Human |
Total daily physical activity |
PF |
|
Older adults |
2019 |
31046115 |
3858 |
Parkinson disease |
Human |
Postural stiffening(fatigue) |
RF |
|
|
2021 |
34180424 |
1568 |
Parkinson disease |
Human |
loneliness |
RF |
Diagnosis |
|
2023 |
37782489 |
3817 |
Lewy Body Disease,Parkinson disease |
Human |
Minor hallucinations (MH) |
RF |
Diagnosis |
|
2021 |
34816426 |
4278 |
Parkinson disease |
Human |
TTH(Tension-type headache) |
RF |
Diagnosis |
|
2017 |
29416761 |
4272 |
Parkinson disease |
Human |
Stress |
RF |
Diagnosis |
|
2013 |
22396022 |
4274 |
Parkinson disease |
Human |
Stress |
RF |
Diagnosis |
Major stressful events: death of a spouse, divorce or marital separation, imprisonment, death of a close family member, personal injury or illness, dismissal from work, marital reconciliation, retirement, and changes in health condition of family members |
2013 |
24125560 |
4269 |
Parkinson disease |
Human |
Unemployment |
RF |
Diagnosis |
|
2010 |
20602449 |
4270 |
Parkinson disease |
Human |
Unemployment |
RF |
Diagnosis |
|
2010 |
20602449 |
4268 |
Parkinson disease |
Human |
Never married |
RF |
Diagnosis |
|
2010 |
20602449 |
1296 |
Parkinson disease |
Human |
Major life events |
PF |
Diagnosis |
|
2010 |
20602449 |
4277 |
Parkinson disease |
Human |
Anxiety |
RF |
Diagnosis |
|
2015 |
26031920 |
3831 |
Parkinson disease |
Human |
Anxiety |
RF |
Prognosis |
|
2021 |
34897102 |
4276 |
Parkinson disease |
Human |
Anxiety |
RF |
Diagnosis |
|
2015 |
26031920 |
1365 |
Parkinson disease |
Human |
Anxiety |
RF |
Prognosis |
during COVID-19 pandemic |
2021 |
33481879 |
4275 |
Parkinson disease |
Human |
Anxiety |
RF |
Diagnosis |
|
2015 |
26031920 |
3385 |
Parkinson disease |
Human |
Anxiety |
RF |
|
|
2003 |
12784267 |
4267 |
Parkinson disease |
Human |
Anxiety |
RF |
Diagnosis |
The phobic anxiety scale of the Crown–Crisp experiential
index measures personality traits and symptoms of
phobic anxiety and has been validated in psychiatric
outpatients. |
2003 |
12784267 |
1361 |
Parkinson disease |
Human |
Depression |
RF |
Prognosis |
during COVID-19 pandemic |
2021 |
33481879 |
4264 |
Parkinson disease |
Human |
Depression |
RF |
Diagnosis |
|
1993 |
8414014 |
3873 |
Parkinson disease |
Human |
Depression |
RF |
Prognosis |
early-stage PD |
2021 |
33633560 |
4266 |
Parkinson disease |
Human |
Depression |
RF |
Diagnosis |
|
2001 |
11574106 |
4271 |
Parkinson disease |
Human |
Depression |
RF |
Diagnosis |
|
2011 |
21951955 |
2408 |
Parkinson disease |
Human |
Depression |
RF |
|
Previous history of depression |
2010 |
21059511 |
1843 |
Parkinson disease |
Human |
Depression |
RF |
|
|
2013 |
24089392 |
1564 |
Parkinson disease |
Human |
Depression |
RF |
Diagnosis |
|
2023 |
36692249 |
4273 |
Parkinson disease |
Human |
Depression |
RF |
Diagnosis |
|
2013 |
24089392 |
3087 |
Parkinson disease |
Human |
Depression |
RF |
Prognosis |
|
2021 |
34021898 |
4265 |
Parkinson disease |
Human |
Depression |
RF |
Diagnosis |
A mean latency of 22 (SE=2.66) years passed between the onset of the first reported symptoms of depression and onset of PD. |
1999 |
10581500 |
4262 |
Parkinson disease |
Human |
EDS(Excessive daytime sleepiness) |
RF |
Diagnosis |
men with EDS reported napping longer than men without EDS (69 vs 42 minutes, p 0.001). An excess of insomnia was also observed in men with EDS (39.0% with EDS and 28.7% without EDS, p 0.001). In addition, grogginess was more likely in the presence of EDS (13%) vs its absence (2.5%, p 0.001), and |
2005 |
16275833 |
4261 |
Parkinson disease |
Human |
Central obesity |
RF |
Diagnosis |
|
2004 |
15003958 |
4260 |
Parkinson disease |
Human |
Central obesity |
RF |
Diagnosis |
|
2004 |
15003958 |
4259 |
Parkinson disease |
Human |
Increased triceps skinfold thickness measured in midlife |
RF |
Diagnosis |
Among the measures of adiposity,age-adjusted incidence of PD increased threefold from 3.7/10,000 person-years in the bottom quartile of TSF (1 to 5 mm) to 11.1/10,000 person-years in the top quartile (11 to 32 mm, p 0.001). |
2002 |
12370461 |
4258 |
Parkinson disease |
Human |
General anaesthesia |
RF |
Diagnosis |
|
2002 |
11903115 |
1293 |
Parkinson disease |
Human |
BMI |
PF |
Diagnosis |
|
2017 |
28609445 |
4263 |
Parkinson disease |
Human |
BMI |
RF |
Diagnosis |
|
2014 |
24633681 |
1292 |
Parkinson disease |
Human |
BMI |
PF |
Diagnosis |
|
2006 |
16542169 |
410 |
Parkinson disease |
Human |
BMI |
PF |
Diagnosis |
infection with hepatitis C virus (HCV) |
2023 |
36872452 |
1294 |
Parkinson disease |
Human |
Physical fitness |
PF |
Diagnosis |
Physical fitness (high vs. low: hazard ratio: 0.239, 95% CI: 0.079-0.725, p?=?.011);Exercise capacity was
expressed as metabolic equivalents (METs) estimated
from peak treadmill speed and grade. |
2018 |
29667433 |
1531 |
Parkinson disease |
Human |
Obesity |
RF |
|
|
2019 |
31019987 |
1291 |
Parkinson disease |
Human |
AET(Aerobic exercise training) |
PF |
Treatment |
Hoehn & Yahr ≤ 2 |
2018 |
30254577 |
1290 |
Parkinson disease |
Human |
Low-intensity progressive cycling exercise |
PF |
Treatment |
|
2018 |
29629527 |
1289 |
Parkinson disease |
Human |
Aquatic Ai Chi |
PF |
Treatment |
Hoehn & Yahr(1-3) |
2018 |
29458923 |
1287 |
Parkinson disease |
Human |
Set dancing |
PF |
Treatment |
Hoehn & Yahr(1-2.5) |
2017 |
28336345 |
1285 |
Parkinson disease |
Human |
Strength training |
PF |
Treatment |
|
2017 |
27585055 |
1284 |
Parkinson disease |
Human |
Highly Challenging Balance Program |
PF |
Treatment |
Hoehn & Yahr(2-3);The Mini-BESTest assesses dynamic balance and contains 14 items from the original BESTest.The Falls Efficacy Scale-International (FES-I) is a self-report questionnaire developed for use in elderly populations to assess fear of falling. |
2016 |
26655100 |
1282 |
Parkinson disease |
Human |
PWT(Power training ) |
PF |
Treatment |
Hoehn and Yahr Scale I-III(2.2±0.6) |
2015 |
26546987 |
1281 |
Parkinson disease |
Human |
Participation in sports and social activities |
PF |
Diagnosis |
|
2015 |
26345784 |
1280 |
Parkinson disease |
Human |
Baduanjin Qigong |
PF |
Treatment |
For mild to moderate Parkinson's disease(Stage 2 to 3 of the Hoehn and Yahr scales) |
2016 |
26310941 |
1279 |
Parkinson disease |
Human |
Dance |
PF |
Treatment |
|
2015 |
25847558 |
1276 |
Parkinson disease |
Human |
Yoga |
PF |
Treatment |
Thirteen people with stage 1-2 PD were randomized to either a yoga (n = 8) or a control group (n = 5). |
2015 |
25558138 |
1283 |
Parkinson disease |
Human |
Yoga |
PF |
Treatment |
Hoehn and Yahr Scale I-III(2.2±0.7) |
2015 |
26546987 |
1273 |
Parkinson disease |
Human |
Outdoor activity |
PF |
Diagnosis |
|
2014 |
25294382 |
1274 |
Parkinson disease |
Human |
Outdoor activity |
PF |
Diagnosis |
|
2014 |
25294382 |
1272 |
Parkinson disease |
Human |
Qigong |
PF |
Treatment |
|
2015 |
25233147 |
1270 |
Parkinson disease |
Human |
Heavy exercise |
PF |
Diagnosis |
|
2014 |
24633681 |
1268 |
Parkinson disease |
Human |
Tai Chi |
PF |
Treatment |
People with stage 2-3 PD |
2013 |
24285965 |
1269 |
Parkinson disease |
Human |
Tai Chi |
PF |
Treatment |
|
2014 |
24519923 |
1271 |
Parkinson disease |
Human |
Tai Chi |
PF |
Treatment |
Hoehn and Yahr Scale I-III |
2014 |
25140088 |
1266 |
Parkinson disease |
Human |
Nordic walking |
PF |
Treatment |
Hoehn and Yahr stage of 1.6 (range 1–3) |
2008 |
18816697 |
1265 |
Parkinson disease |
Human |
Recreational activity |
PF |
Diagnosis |
MET(Metabolic equivalent task ) |
2008 |
17960818 |
4257 |
Parkinson disease |
Human |
Recreational activity |
RF |
Diagnosis |
|
2015 |
25514902 |
1278 |
Parkinson disease |
Human |
Physical Exercise |
PF |
Diagnosis |
|
2015 |
25834444 |
1277 |
Parkinson disease |
Human |
Physical Exercise |
PF |
Diagnosis |
|
2015 |
25834444 |
1264 |
Parkinson disease |
Human |
Physical Exercise |
PF |
Treatment |
Nineteen patients were in a mild state (range of H&Y from I to II) and three in a moderate state (III of H&Y). |
2005 |
15728289 |
1261 |
Parkinson disease |
Human |
Physical Exercise |
PF |
Diagnosis |
|
1992 |
1558515 |
1286 |
Parkinson disease |
Human |
Aerobic exercise |
PF |
Treatment |
|
2016 |
27655232 |
1288 |
Parkinson disease |
Human |
Exercise |
PF |
Treatment |
H&Y stage(2-3);PD with Pisa syndrome (PS) |
2017 |
28946570 |
847 |
Parkinson disease |
Human |
Exercise |
PF |
|
|
2002 |
12140099 |
1262 |
Parkinson disease |
Human |
Exercise |
PF |
Diagnosis |
|
2002 |
12140099 |
1267 |
Parkinson disease |
Human |
Exercise |
PF |
Treatment |
Stage 2 to 3 of the Hoehn and Yahr scales |
2009 |
19671145 |
848 |
Parkinson disease |
Human |
Exercise |
PF |
|
|
2002 |
12140099 |
1244 |
Parkinson disease |
Human |
Suns |
PF |
Diagnosis |
|
2017 |
28338925 |
1240 |
Parkinson disease |
Human |
Suns(Moist smokeless tobacco ) |
PF |
Diagnosis |
|
2017 |
27940486 |
1242 |
Parkinson disease |
Human |
Suns(Moist smokeless tobacco ) |
PF |
Diagnosis |
|
2017 |
27940486 |
1241 |
Parkinson disease |
Human |
Suns(Moist smokeless tobacco ) |
PF |
Diagnosis |
|
2017 |
27940486 |
1243 |
Parkinson disease |
Human |
Suns(Moist smokeless tobacco ) |
PF |
Diagnosis |
|
2017 |
27940486 |
1232 |
Parkinson disease |
Human |
Time-since-cessation (years) |
PF |
Diagnosis |
|
2014 |
24788751 |
1231 |
Parkinson disease |
Human |
Time-since-cessation (years) |
PF |
Diagnosis |
|
2014 |
24788751 |
1233 |
Parkinson disease |
Human |
Time-since-cessation (years) |
PF |
Diagnosis |
|
2014 |
24788751 |
1230 |
Parkinson disease |
Human |
Time-since-cessation (years) |
PF |
Diagnosis |
|
2014 |
24788751 |
339 |
Parkinson disease |
Human |
Passive smoking |
Not Related |
Diagnosis |
|
2010 |
20175761 |
1218 |
Parkinson disease |
Human |
Passive smoking |
PF |
Diagnosis |
Among persons whose only tobacco smoke exposure was passive smoking at home, risk was inversely associated with years exposed. |
2012 |
22095755 |
338 |
Parkinson disease |
Human |
Passive smoking |
Not Related |
Diagnosis |
|
2010 |
20175761 |
1203 |
Parkinson disease |
Human |
Cigarette equivalents |
PF |
Diagnosis |
|
2005 |
15521056 |
1202 |
Parkinson disease |
Human |
Cigarette equivalents |
PF |
Diagnosis |
|
2005 |
15521056 |
1191 |
Parkinson disease |
Human |
Exposure to pets |
PF |
Diagnosis |
|
2001 |
11574106 |
1514 |
Parkinson disease |
Human |
Sleep disturbance |
RF |
Diagnosis |
|
2022 |
35013056 |
1560 |
Parkinson disease |
Human |
Sleep disturbance |
RF |
Diagnosis |
|
2022 |
35013056 |
1212 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2010 |
20220126 |
1235 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2015 |
25514902 |
1194 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2001 |
11761476 |
1217 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2010 |
20603187 |
1199 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2003 |
14607318 |
1222 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2014 |
24788751 |
414 |
Parkinson disease |
Human |
Smoking |
PF |
|
|
2019 |
30772279 |
1245 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2017 |
29057010 |
1204 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2006 |
16542169 |
1227 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2014 |
24788751 |
1186 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2001 |
11359079 |
1209 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2010 |
20175761 |
853 |
Parkinson disease |
Human |
Smoking |
PF |
|
|
2000 |
11060508 |
1214 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2010 |
20220126 |
1237 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2012 |
26952952 |
1196 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
The inverse correlation between Parkinson's disease risk and smoking as well as the trend of gradient dose response is again observed in our study. |
2003 |
12964791 |
1219 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2013 |
23377703 |
1201 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2005 |
15521056 |
1224 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2014 |
24788751 |
1183 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
1994 |
8209872 |
1206 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2010 |
20175761 |
724 |
Parkinson disease |
Human |
Smoking |
PF |
|
|
2020 |
32943485 |
1229 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2014 |
24788751 |
1188 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2001 |
11359079 |
1211 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2010 |
20220126 |
1234 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2015 |
25514902 |
1193 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2001 |
11761476 |
1216 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2010 |
20603187 |
773 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2022 |
34649886 |
1239 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2012 |
26952952 |
1198 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
The inverse correlation between Parkinson's disease risk and smoking as well as the trend of gradient dose response is again observed in our study. |
2003 |
12964791 |
1221 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2014 |
24788751 |
1828 |
Parkinson disease |
Human |
Smoking |
RF |
|
|
2021 |
34082149 |
1226 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2014 |
24788751 |
1185 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
1999 |
10581500 |
1208 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2010 |
20175761 |
852 |
Parkinson disease |
Human |
Smoking |
PF |
|
|
2009 |
19540050 |
1190 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2001 |
11359079 |
1213 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2010 |
20220126 |
1236 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2015 |
25925389 |
1195 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2003 |
12847151 |
1200 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2005 |
15468111 |
646 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2022 |
34649886 |
1223 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2014 |
24788751 |
1246 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2018 |
29667433 |
1205 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2008 |
19513320 |
1228 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2014 |
24788751 |
371 |
Parkinson disease |
Human |
Smoking |
PF |
|
|
2021 |
33435977 |
1187 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2001 |
11359079 |
1210 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2010 |
20175761 |
750 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2022 |
34633332 |
854 |
Parkinson disease |
Human |
Smoking |
PF |
|
|
2009 |
19188574 |
1192 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2001 |
11574106 |
1215 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2010 |
20220126 |
1238 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2012 |
26952952 |
582 |
Parkinson disease |
Human |
Smoking |
PF |
|
|
2010 |
21059511 |
1197 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
The inverse correlation between Parkinson's disease risk and smoking as well as the trend of gradient dose response is again observed in our study. |
2003 |
12964791 |
1220 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2014 |
24633681 |
1225 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2014 |
24788751 |
1184 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
1999 |
9921857 |
1207 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2010 |
20175761 |
1189 |
Parkinson disease |
Human |
Smoking |
PF |
Diagnosis |
|
2001 |
11359079 |
407 |
Parkinson disease |
Human |
Education |
PF |
|
|
2021 |
32865628 |
1295 |
Parkinson disease |
Human |
Education |
PF |
Diagnosis |
|
1999 |
10581500 |
3850 |
Parkinson disease |
Human |
Education |
RF |
|
|
2021 |
34421783 |
4239 |
Parkinson disease |
Human |
Education |
RF |
Diagnosis |
Higher education,higher risk |
2005 |
16301484 |
1178 |
Parkinson disease |
Human |
Yerba mate tea |
PF |
Diagnosis |
Linear trend between YM-consumption and the risk of PD |
2015 |
26148934 |
1177 |
Parkinson disease |
Human |
Yerba mate tea |
PF |
Diagnosis |
Linear trend between YM-consumption and the risk of PD |
2015 |
26148934 |
1173 |
Parkinson disease |
Primary cell culture model of PD |
Anthocyanin-and proanthocyanidin-rich botanical extracts |
PF |
Treatment |
|
2014 |
24502982 |
1170 |
Parkinson disease |
Human |
N-3 PUFAs(N-3 polyunsaturated fatty acids) |
PF |
Diagnosis |
OR calculated by Highest vs. lowest tertile |
2014 |
24120951 |
4223 |
Parkinson disease |
Human |
High liquor |
RF |
Diagnosis |
|
2013 |
23840473 |
1168 |
Parkinson disease |
Human |
Pepper |
PF |
Diagnosis |
The potentially protective effect of edible Solanaceae largely occurred in men and women who had never used tobacco or who had smoked cigarettes < 10 years. |
2013 |
23661325 |
1167 |
Parkinson disease |
Human |
Vitamin D3 |
PF |
Treatment |
|
2013 |
23485413 |
1165 |
Parkinson disease |
Human |
Dietary flavonoids |
PF |
Diagnosis |
|
2012 |
22491871 |
1164 |
Parkinson disease |
Human |
Healthy pattern(High intake of vegetables,seaweed,pulses,mushrooms,fruits and fish) |
PF |
Diagnosis |
|
2012 |
22136555 |
1162 |
Parkinson disease |
Human |
Zinc |
PF |
Diagnosis |
|
2011 |
21497832 |
1161 |
Parkinson disease |
Human |
Magnesium |
PF |
Diagnosis |
|
2011 |
21497832 |
1158 |
Parkinson disease |
Human |
Japanese and Chinese teas |
PF |
Diagnosis |
|
2011 |
21458354 |
4220 |
Parkinson disease |
Human |
Japanese sake |
RF |
Diagnosis |
|
2010 |
21054827 |
1157 |
Parkinson disease |
Human |
β-Carotene |
PF |
Diagnosis |
|
2011 |
20491891 |
4219 |
Parkinson disease |
Human |
Spring water |
RF |
Diagnosis |
|
2010 |
20402575 |
4215 |
Parkinson disease |
Human |
Blubber consumption |
RF |
Diagnosis |
|
2008 |
18455239 |
4214 |
Parkinson disease |
Human |
Whale meat consumption |
RF |
Diagnosis |
|
2008 |
18455239 |
4212 |
Parkinson disease |
Human |
Cholesterol + Iron |
RF |
Diagnosis |
|
2009 |
18424169 |
1160 |
Parkinson disease |
Human |
Iron |
PF |
Diagnosis |
|
2011 |
21497832 |
4211 |
Parkinson disease |
Human |
Iron |
RF |
Diagnosis |
|
2009 |
18424169 |
1146 |
Parkinson disease |
Human |
Vitamin B6 |
PF |
Diagnosis |
|
2006 |
16864826 |
4217 |
Parkinson disease |
Human |
Vitamin B6 |
RF |
Diagnosis |
|
2010 |
20338075 |
4207 |
Parkinson disease |
Human |
High intake of iron+high manganese intake |
RF |
Diagnosis |
|
2003 |
12796527 |
1135 |
Parkinson disease |
Human |
Caffee |
PF |
Diagnosis |
Do not use postmenopausal hormones |
2003 |
12629235 |
4206 |
Parkinson disease |
Human |
Caffee |
RF |
Diagnosis |
postmenopausal hormone users |
2003 |
12629235 |
4205 |
Parkinson disease |
Human |
Sour cream |
RF |
Diagnosis |
|
2002 |
12447934 |
4204 |
Parkinson disease |
Human |
Cream cheese |
RF |
Diagnosis |
|
2002 |
12447934 |
2268 |
Parkinson disease |
Human |
Total dairy |
RF |
Diagnosis |
|
2022 |
34997937 |
4210 |
Parkinson disease |
Human |
Total dairy |
RF |
Diagnosis |
|
2007 |
17272289 |
1518 |
Parkinson disease |
Human |
Total dairy |
RF |
Diagnosis |
|
2022 |
34997937 |
4238 |
Parkinson disease |
Human |
Total dairy |
RF |
Diagnosis |
|
2017 |
28596209 |
4209 |
Parkinson disease |
Human |
Total dairy |
RF |
Diagnosis |
|
2007 |
17272289 |
4203 |
Parkinson disease |
Human |
Total dairy |
RF |
Diagnosis |
|
2002 |
12447934 |
4226 |
Parkinson disease |
Human |
Well water |
RF |
Diagnosis |
Source of drinking water |
2014 |
25097376 |
4218 |
Parkinson disease |
Human |
Well water |
RF |
Diagnosis |
|
2010 |
20402575 |
4200 |
Parkinson disease |
Human |
Well water |
RF |
Diagnosis |
|
2001 |
11574106 |
4202 |
Parkinson disease |
Human |
Well water |
RF |
Diagnosis |
|
2002 |
12140099 |
1128 |
Parkinson disease |
Human |
Well water |
PF |
Diagnosis |
|
1999 |
10581500 |
4201 |
Parkinson disease |
Human |
Well water |
RF |
Diagnosis |
|
2002 |
11903115 |
4216 |
Parkinson disease |
Human |
Well water |
RF |
Diagnosis |
Rural water drinking |
2008 |
19513320 |
1147 |
Parkinson disease |
Human |
Coffee |
PF |
Diagnosis |
|
2008 |
17522612 |
1171 |
Parkinson disease |
Human |
Coffee |
PF |
Diagnosis |
|
2013 |
24125560 |
1129 |
Parkinson disease |
Human |
Coffee |
PF |
Diagnosis |
10.4 per 10,000 person-years in men who drank no coffee |
2000 |
10819950 |
1139 |
Parkinson disease |
Human |
Coffee |
PF |
Diagnosis |
|
2003 |
12902625 |
1149 |
Parkinson disease |
Human |
Coffee |
PF |
Diagnosis |
|
2007 |
17712848 |
1141 |
Parkinson disease |
Human |
Coffee |
PF |
Diagnosis |
|
2003 |
12902625 |
1138 |
Parkinson disease |
Human |
Coffee |
PF |
Diagnosis |
|
2003 |
12902625 |
1143 |
Parkinson disease |
Human |
Coffee |
PF |
Diagnosis |
|
2003 |
14607318 |
4227 |
Parkinson disease |
Human |
Coffee |
RF |
Diagnosis |
|
2012 |
26952952 |
1130 |
Parkinson disease |
Human |
Coffee |
PF |
Diagnosis |
|
2001 |
11359079 |
1159 |
Parkinson disease |
Human |
Coffee |
PF |
Diagnosis |
|
2011 |
21458354 |
1182 |
Parkinson disease |
Human |
Coffee |
PF |
Diagnosis |
|
2017 |
29057010 |
1140 |
Parkinson disease |
Human |
Coffee |
PF |
Diagnosis |
|
2003 |
12902625 |
1150 |
Parkinson disease |
Human |
Coffee |
PF |
Diagnosis |
|
2007 |
17712848 |
1166 |
Parkinson disease |
Human |
Coffee |
PF |
Diagnosis |
|
2012 |
22927157 |
1153 |
Parkinson disease |
Human |
Tea |
PF |
Diagnosis |
|
2010 |
20353703 |
1144 |
Parkinson disease |
Human |
Tea |
PF |
Diagnosis |
|
2003 |
14607318 |
1148 |
Parkinson disease |
Human |
Tea |
PF |
Diagnosis |
|
2007 |
17712848 |
1172 |
Parkinson disease |
Human |
Tea |
PF |
Diagnosis |
|
2013 |
24125560 |
1132 |
Parkinson disease |
Human |
Tea |
PF |
Diagnosis |
|
2002 |
11943691 |
4353 |
Parkinson disease |
Human |
Potatoes |
RF |
Diagnosis |
Crop exposure |
2018 |
29136149 |
1181 |
Parkinson disease |
Human |
Beta-carotene |
PF |
Diagnosis |
|
2017 |
28881039 |
1180 |
Parkinson disease |
Human |
Beta-carotene |
PF |
Diagnosis |
|
2017 |
28881039 |
1179 |
Parkinson disease |
Human |
Beta-carotene |
PF |
Diagnosis |
|
2017 |
28881039 |
4208 |
Parkinson disease |
Human |
Milk |
RF |
Diagnosis |
|
2005 |
15781824 |
4222 |
Parkinson disease |
Human |
Milk |
RF |
Diagnosis |
|
2013 |
23377703 |
4213 |
Parkinson disease |
Human |
Saturated fat |
RF |
Diagnosis |
|
2009 |
18424169 |
4231 |
Parkinson disease |
Human |
Alcohol types |
RF |
Diagnosis |
|
2012 |
26952952 |
4233 |
Parkinson disease |
Human |
Alcohol types |
RF |
Diagnosis |
|
2012 |
26952952 |
1136 |
Parkinson disease |
Human |
Alcohol types |
PF |
Diagnosis |
|
2003 |
12891669 |
4230 |
Parkinson disease |
Human |
Alcohol types |
RF |
Diagnosis |
|
2012 |
26952952 |
4232 |
Parkinson disease |
Human |
Alcohol types |
RF |
Diagnosis |
|
2012 |
26952952 |
1169 |
Parkinson disease |
Human |
Alcohol types |
PF |
Diagnosis |
|
2013 |
23840473 |
4229 |
Parkinson disease |
Human |
Alcohol types |
RF |
Diagnosis |
|
2012 |
26952952 |
1137 |
Parkinson disease |
Human |
Alcohol types |
PF |
Diagnosis |
|
2003 |
12891669 |
1145 |
Parkinson disease |
Human |
Meat |
PF |
Diagnosis |
|
2006 |
16542169 |
1152 |
Parkinson disease |
Human |
Cholesterol |
PF |
Diagnosis |
|
2009 |
18424169 |
1175 |
Parkinson disease |
Human |
Caffeine |
PF |
Diagnosis |
|
2015 |
25925389 |
374 |
Parkinson disease |
Human |
Caffeine |
PF |
|
|
2021 |
33435977 |
1174 |
Parkinson disease |
Human |
Vitamin D |
PF |
Diagnosis |
|
2014 |
25294382 |
1163 |
Parkinson disease |
Human |
Probiotic |
PF |
Treatment |
Treated with levodopa |
2011 |
21587143 |
2025 |
Parkinson disease |
Human |
Alcohol |
RF |
Diagnosis |
|
2023 |
36342675 |
1176 |
Parkinson disease |
Human |
Alcohol |
PF |
Diagnosis |
|
2015 |
25925389 |
4236 |
Parkinson disease |
Human |
Alcohol |
RF |
Diagnosis |
|
2012 |
26952952 |
4228 |
Parkinson disease |
Human |
Alcohol |
RF |
Diagnosis |
|
2012 |
26952952 |
1131 |
Parkinson disease |
Human |
Alcohol |
PF |
Diagnosis |
|
2001 |
11359079 |
4225 |
Parkinson disease |
Human |
Alcohol |
RF |
Diagnosis |
|
2014 |
24633681 |
334 |
Parkinson disease |
Human |
Alcohol |
Not Related |
Diagnosis |
|
2012 |
22714720 |
4235 |
Parkinson disease |
Human |
Alcohol |
RF |
Diagnosis |
|
2012 |
26952952 |
4237 |
Parkinson disease |
Human |
Alcohol |
RF |
Diagnosis |
|
2012 |
26952952 |
4224 |
Parkinson disease |
Human |
Alcohol |
RF |
Diagnosis |
|
2013 |
24314068 |
4234 |
Parkinson disease |
Human |
Alcohol |
RF |
Diagnosis |
|
2012 |
26952952 |
4221 |
Parkinson disease |
Human |
Alcohol |
RF |
Diagnosis |
|
2011 |
21951955 |
1142 |
Parkinson disease |
Human |
Alcohol |
PF |
Diagnosis |
|
2003 |
12902625 |
459 |
Parkinson disease |
Human |
Mediterranean diet(MeDi) |
PF |
Diagnosis |
|
2023 |
36692092 |
1134 |
Parkinson disease |
Human |
Vitamin E(D) |
PF |
Diagnosis |
|
2002 |
12391343 |
337 |
Parkinson disease |
Human |
Carotenoids |
Not Related |
Diagnosis |
|
2016 |
27787934 |
336 |
Parkinson disease |
Human |
Vitamin C |
Not Related |
Diagnosis |
|
2016 |
27787934 |
335 |
Parkinson disease |
Human |
Vitamin E |
Not Related |
Diagnosis |
|
2016 |
27787934 |
1126 |
Parkinson disease |
Human |
Vitamin E |
PF |
Diagnosis |
|
1988 |
3196195 |
1155 |
Parkinson disease |
Human |
Vitamin E |
PF |
Diagnosis |
|
2011 |
20491891 |
1133 |
Parkinson disease |
Human |
Vitamin E |
PF |
Diagnosis |
|
2002 |
12391343 |
1154 |
Parkinson disease |
Human |
Vitamin E |
PF |
Diagnosis |
|
2011 |
20491891 |
1127 |
Parkinson disease |
Human |
Vitamin E |
PF |
Diagnosis |
|
1997 |
9193212 |
1156 |
Parkinson disease |
Human |
Vitamin E |
PF |
Diagnosis |
|
2011 |
20491891 |