Progressive Supranuclear Palsy

Progressive supranuclear palsy (PSP), also known as Steele–Richardson–Olszewski syndrome, is a degenerative disease involving the gradual deterioration and death of specific volumes of the brain.[1]

The condition leads to symptoms including loss of balance, slowing of movement, difficulty moving the eyes, and dementia.[1] PSP may be mistaken for other neurodegenerative diseases such as Parkinson's and Alzheimer's. The cause of the condition is uncertain, but involves accumulation of tau protein within the brain. Medications such as levodopa and amantadine may be useful in some cases.[1]


[1]Golbe LI (April 2014). "Progressive supranuclear palsy". Seminars in Neurology. 34 (2): 151–9. doi:10.1055/s-0034-1381736. PMID 24963674.

The search result for the NDD Category "Progressive Supranuclear Palsy"
A total of 59 results found based on your keywords
RF_ID Disease Name Species RF_Name Association Phase Condition Year PMID
355 Progressive Supranuclear Palsy Human Occupational types Not Related Diagnosis 2009 19864660
3192 Progressive Supranuclear Palsy Human APOE RF 2003 12552038
779 Progressive Supranuclear Palsy Human DUSP10 PF Meta-analysis 2018 29986742
765 Progressive Supranuclear Palsy Human EIF2AK3 PF Meta-analysis 2018 29986742
2038 Progressive Supranuclear Palsy Human EIF2AK3 RF Diagnosis 2021 33897612
618 Progressive Supranuclear Palsy Human MAPT PF Meta-analysis 2018 29986742
498 Progressive Supranuclear Palsy Human MAPT PF Diagnosis 2021 33897612
2582 Progressive Supranuclear Palsy Human MAPT RF Diagnosis 2021 33897612
3037 Progressive Supranuclear Palsy Human MAPT RF Meta-analysis 2018 29986742
715 Progressive Supranuclear Palsy Human MOBP PF Meta-analysis 2018 29986742
709 Progressive Supranuclear Palsy Human SLCO1A2 PF Meta-analysis 2018 29986742
775 Progressive Supranuclear Palsy Human STX6 PF Meta-analysis 2018 29986742
3349 Progressive Supranuclear Palsy Human tau A0/A0 genotype RF 1998 9708963
3348 Progressive Supranuclear Palsy Human tau A0/A0 genotype RF 1998 9708963
3069 Progressive Supranuclear Palsy Human VEGF haplotypes(AGG) RF 2010 20413880
1834 Progressive Supranuclear Palsy Human gene-environment interactions RF Diagnosis 2021 33897612
1835 Progressive Supranuclear Palsy Human gene-environment interactions RF Diagnosis 2021 33897612
3880 Progressive Supranuclear Palsy Human cerebrovascular disease RF Diagnosis 2021 33967937
3879 Progressive Supranuclear Palsy Human Diabetes RF Diagnosis 2021 33967937
2039 Progressive Supranuclear Palsy Human exposure to organic solvents RF self-reporting exposure to organic solvents 2016 26854325
2085 Progressive Supranuclear Palsy Human Exposure to Pesticide RF self-reporting exposure to pesticides 2016 26854325
2092 Progressive Supranuclear Palsy Human have worked in transportation RF 2016 26854325
1984 Progressive Supranuclear Palsy Human living on a farm or ranch RF more years living on a farm or ranch 2016 26854325
1959 Progressive Supranuclear Palsy Human more years living within one mile of an agricultural area RF more years living within one mile of an agricultural area 2016 26854325
2011 Progressive Supranuclear Palsy Human Occupational Exposure RF occupational metal exposure 2016 26854325
356 Progressive Supranuclear Palsy Human Occupational exposure Not Related Diagnosis 2009 19864660
358 Progressive Supranuclear Palsy Human Occupational exposure Not Related Diagnosis 2009 19864660
357 Progressive Supranuclear Palsy Human Occupational exposure Not Related Diagnosis 2009 19864660
2542 Progressive Supranuclear Palsy Human Use of firearm in service RF 2018 29973911
2474 Progressive Supranuclear Palsy Human beta-blocker use RF 2019 31420308
860 Progressive Supranuclear Palsy Human high levels of uric acid PF 2016 26686202
2111 Progressive Supranuclear Palsy Human Hypertension RF in the multi-variate analysis 2019 31420308
2169 Progressive Supranuclear Palsy Human Hypertension RF 2019 31420308
362 Progressive Supranuclear Palsy Human Corticoids Not Related Diagnosis 2009 19864660
361 Progressive Supranuclear Palsy Human Non-steroidal anti-inflammatory drug (except aspirin) Not Related Diagnosis 2009 19864660
360 Progressive Supranuclear Palsy Human Aspirin Not Related Diagnosis 2009 19864660
359 Progressive Supranuclear Palsy Human Anti-inflammatory agent Not Related Diagnosis 2009 19864660
354 Progressive Supranuclear Palsy Human Living in village or isolated farm Not Related Diagnosis 2009 19864660
1328 Progressive Supranuclear Palsy Human Firearm usage PF Diagnosis 2018 29973911
2000 Progressive Supranuclear Palsy Human higher number of years of drinking well water RF 2016 26854325
2837 Progressive Supranuclear Palsy Human high exposure to highly stressful events RF 2017 28409749
4376 Progressive Supranuclear Palsy Human High stress events RF Diagnosis 2017 28409749
353 Progressive Supranuclear Palsy Human Depression Not Related Diagnosis 2009 19864660
352 Progressive Supranuclear Palsy Human Depression Not Related Diagnosis 2009 19864660
351 Progressive Supranuclear Palsy Human Smoking types Not Related Diagnosis 2009 19864660
350 Progressive Supranuclear Palsy Human Smoking types Not Related Diagnosis 2009 19864660
743 Progressive Supranuclear Palsy Human Education PF in the multi-variate analysis 2019 31420308
845 Progressive Supranuclear Palsy Human Education PF 2018 29973911
1326 Progressive Supranuclear Palsy Human Education PF Diagnosis 2018 29973911
745 Progressive Supranuclear Palsy Human Education PF 2019 31420308
4375 Progressive Supranuclear Palsy Human Education RF Diagnosis 2009 19864660
1327 Progressive Supranuclear Palsy Human Education PF Diagnosis 1996 8710069
4374 Progressive Supranuclear Palsy Human Well water RF Diagnosis 2016 26854325
348 Progressive Supranuclear Palsy Human Coffee Not Related Diagnosis 2009 19864660
349 Progressive Supranuclear Palsy Human Tea Not Related Diagnosis 2009 19864660
346 Progressive Supranuclear Palsy Human Alcohol types Not Related Diagnosis 2009 19864660
345 Progressive Supranuclear Palsy Human Alcohol types Not Related Diagnosis 2009 19864660
347 Progressive Supranuclear Palsy Human Alcohol types Not Related Diagnosis 2009 19864660
344 Progressive Supranuclear Palsy Human Alcohol status Not Related Diagnosis 2009 19864660
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