Progressive Supranuclear Palsy

Progressive supranuclear palsy (PSP), also known as Steele–Richardson–Olszewski syndrome, is a degenerative disease involving the gradual deterioration and death of specific volumes of the brain.[1]

The condition leads to symptoms including loss of balance, slowing of movement, difficulty moving the eyes, and dementia.[1] PSP may be mistaken for other neurodegenerative diseases such as Parkinson's and Alzheimer's. The cause of the condition is uncertain, but involves accumulation of tau protein within the brain. Medications such as levodopa and amantadine may be useful in some cases.[1]


[1]Golbe LI (April 2014). "Progressive supranuclear palsy". Seminars in Neurology. 34 (2): 151–9. doi:10.1055/s-0034-1381736. PMID 24963674.

The search result for the NDD Category "Progressive Supranuclear Palsy"
A total of 27 results found based on your keywords
RF_ID Disease Name Species RF_Name Association Condition PMID
15 progressive supranuclear palsy human APOE RF 12552038
95 progressive supranuclear palsy human DUSP10 PF Meta-analysis 29986742
97 progressive supranuclear palsy human EIF2AK3 PF Meta-analysis 29986742
173 progressive supranuclear palsy human MAPT RF Meta-analysis 29986742
173 progressive supranuclear palsy human MAPT PF Meta-analysis 29986742
174 progressive supranuclear palsy human MAPT H1c haplotype RF 28100725
184 progressive supranuclear palsy human MOBP PF Meta-analysis 29986742
252 progressive supranuclear palsy human SLCO1A2 PF Meta-analysis 29986742
269 progressive supranuclear palsy human STX6 PF Meta-analysis 29986742
276 progressive supranuclear palsy human tau A0/A0 genotype RF 9708963
304 progressive supranuclear palsy human VEGF haplotypes(AGG) RF 20413880
356 progressive supranuclear palsy human beta-blocker use RF 31420308
425 progressive supranuclear palsy human education PF 29973911
425 progressive supranuclear palsy human education PF 31420308
425 progressive supranuclear palsy human education PF in the multi-variate analysis 31420308
442 progressive supranuclear palsy human exposure to organic solvents RF self-reporting exposure to organic solvents 26854325
444 progressive supranuclear palsy human Exposure to Pesticide RF self-reporting exposure to pesticides 26854325
472 progressive supranuclear palsy human have worked in transportation RF 26854325
490 progressive supranuclear palsy human high exposure to highly stressful events RF 28409749
499 progressive supranuclear palsy human higher number of years of drinking well water RF 26854325
506 progressive supranuclear palsy human hypertension RF 31420308
506 progressive supranuclear palsy human hypertension RF in the multi-variate analysis 31420308
542 progressive supranuclear palsy human living on a farm or ranch RF more years living on a farm or ranch 26854325
563 progressive supranuclear palsy human more years living within one mile of an agricultural area RF more years living within one mile of an agricultural area 26854325
579 progressive supranuclear palsy human Occupational Exposure RF occupational metal exposure 26854325
691 progressive supranuclear palsy human Use of firearm in service RF 29973911
773 progressive supranuclear palsy human high levels of uric acid PF 26686202
logo
All rights reserved: Institutes for Systems Genetics, West China Hospital