RF_ID |
Disease Name |
Species |
RF_Name |
Association |
Condition |
PMID |
308 |
Amyotrophic lateral sclerosis |
human |
20% continuous increase of any agricultural land or specific crop type |
RF |
Total agricultural land |
28851431 |
308 |
Amyotrophic lateral sclerosis |
human |
20% continuous increase of any agricultural land or specific crop type |
RF |
Orchards |
28851431 |
308 |
Amyotrophic lateral sclerosis |
human |
20% continuous increase of any agricultural land or specific crop type |
RF |
Olive groves |
28851431 |
309 |
Alzheimer's disease |
human |
25(OH)D deficiency |
PF |
|
28522216 |
310 |
Alzheimer's Disease |
human |
a decrease in LRP10 function |
RF |
|
22734645 |
311 |
Amyotrophic Lateral Sclerosis |
human |
A high intake of carbohydrate |
RF |
|
17852010 |
312 |
Alzheimer’s Disease |
human |
A priori occupations |
RF |
Printers, mechanics, garage workers, oilers, painters, auto body workers, wood finishers, shoemakers, and dry cleaners (as one of two longest held occupations). |
7771442 |
313 |
Alzheimer’s Disease |
human |
Activities of daily living assistance |
RF |
after Hemodialysis Initiation |
30093374 |
314 |
Tourette Syndrome |
human |
ADHD family history positive |
RF |
|
20654033 |
315 |
Parkinson's Disease |
human |
Obesity |
RF |
|
31019987 |
316 |
Tuberous sclerosis complex |
human |
administration of multiple antiepileptic drugs |
RF |
|
20113608 |
317 |
Parkinson's Disease |
human |
Adult nutrient intake |
RF |
|
10661654 |
318 |
Alzheimer's disease |
human |
African ancestry |
RF |
|
28369008 |
319 |
Alzheimer's Disease |
human |
Age |
RF |
in females |
26343475 |
319 |
Alzheimer's Disease |
human |
Age |
RF |
|
22976076 |
319 |
Alzheimer’s Disease |
human |
Age |
RF |
|
30103328 |
319 |
Alzheimer’s Disease |
human |
Age |
RF |
after Hemodialysis Initiation |
30093374 |
319 |
Alzheimer’s Disease |
human |
Age |
RF |
after Hemodialysis Initiation |
30093374 |
319 |
Alzheimer’s Disease |
human |
Age |
RF |
after Hemodialysis Initiation |
30093374 |
319 |
Alzheimer’s Disease |
human |
Age |
RF |
after Hemodialysis Initiation |
30093374 |
319 |
Alzheimer's Disease |
human |
Age |
RF |
|
25624416 |
319 |
Alzheimer's Disease |
human |
Age |
RF |
|
25401488 |
319 |
Alzheimer's Disease |
human |
Age |
RF |
|
20016220 |
319 |
Alzheimer's disease |
human |
Age |
RF |
|
31058682 |
319 |
Alzheimer's disease |
human |
Age |
RF |
|
24489845 |
319 |
Alzheimer's disease |
human |
Age |
RF |
|
22526079 |
319 |
Amyotrophic lateral sclerosis |
rat |
Age |
RF |
|
30873018 |
319 |
Parkinson's Disease |
human |
Age |
PF |
GCH1 genotype T allele carries |
27871051 |
319 |
Parkinson's Disease |
rhesus monkey |
Age |
RF |
|
21587290 |
319 |
Parkinson's Disease |
human |
Age |
RF |
|
17884509 |
319 |
Alzheimer's Disease |
human |
Age |
RF |
|
28806610 |
319 |
Alzheimer's disease |
human |
Age |
RF |
people with mild cognitive impairment (MCI) |
21518614 |
319 |
Alzheimer's disease |
human |
Age |
RF |
in patients after spine surgery |
20375503 |
320 |
Amyotrophic Lateral Sclerosis |
human |
Age at cessation of smoking |
RF |
|
16963407 |
321 |
Amyotrophic lateral sclerosis |
human |
Age at first trauma leading to functional disability |
RF |
<35 years |
29063790 |
321 |
Amyotrophic lateral sclerosis |
human |
Age at first trauma leading to functional disability |
RF |
35–54 years |
29063790 |
321 |
Amyotrophic lateral sclerosis |
human |
Age at first trauma leading to functional disability |
RF |
35–54 years |
29063790 |
322 |
Motor Neuron Disease |
human |
Age at menarche |
RF |
Age at menarche: >=16 |
1745327 |
323 |
Motor Neuron Disease |
human |
Age at natural menopause |
RF |
Age at natural menopause: 45-49 |
1745327 |
323 |
Motor Neuron Disease |
human |
Age at natural menopause |
RF |
Age at natural menopause: <=44 |
1745327 |
324 |
Alzheimer’s Disease |
human |
age in first degree relatives |
RF |
age of 90 in first degree relatives |
8411049 |
325 |
Tuberous sclerosis complex |
human |
age of onset |
RF |
|
20113608 |
326 |
Amyotrophic lateral sclerosis |
human |
Age of sport activity onset |
PF |
|
24706338 |
326 |
Amyotrophic lateral sclerosis |
human |
Age of sport activity onset |
PF |
Significant adjusted OR |
24706338 |
326 |
Amyotrophic lateral sclerosis |
human |
Age of sport activity onset |
PF |
|
24706338 |
327 |
Alzheimer's disease |
human |
age-associated decline in health status |
RF |
the nontraditional risk factors index [FI-NTRF] was constructed for predict Alzheimer disease and dementia |
21753161 |
328 |
Amyotrophic Lateral Sclerosis |
human |
Agricultural chemicals |
RF |
|
20012543 |
329 |
Amyotrophic lateral sclerosis |
human |
Agricultural chemicals (pesticides) |
RF |
|
29681882 |
330 |
Amyotrophic Lateral Sclerosis |
human |
agricultural work |
RF |
|
15995797 |
331 |
Amyotrophic lateral sclerosis |
human |
Air Force |
RF |
Adjusted for matching factors and socioeconomic status (SES) |
26583610 |
332 |
Alzheimer's disease |
human |
Air pollution |
RF |
|
30741678 |
332 |
Amyotrophic lateral sclerosis |
human |
Air pollution |
RF |
the nitrogen oxides NO2 and NOx |
29483062 |
332 |
Amyotrophic Lateral Sclerosis |
human |
Air pollution |
RF |
Air Pollution Exposure( NOx concentrations) |
29989551 |
332 |
Amyotrophic Lateral Sclerosis |
human |
Air pollution |
RF |
Air Pollution Exposure(NO2) |
29989551 |
332 |
Amyotrophic Lateral Sclerosis |
human |
Air pollution |
RF |
Air Pollution Exposure(PM2.5) |
29989551 |
333 |
Frontotemporal Dementia |
human |
alcohol consumption |
PF |
|
28946566 |
333 |
Frontotemporal Dementia |
human |
alcohol consumption |
PF |
in current alcohol consumers |
28946566 |
334 |
Alzheimer’s Disease |
human |
Alcohol dependence |
PF |
after Hemodialysis Initiation |
30093374 |
335 |
Amyotrophic lateral sclerosis |
human |
Amateur sport activity |
PF |
|
24706338 |
336 |
Alzheimer’s Disease |
human |
amnestic mild cognitive impairment (aMCI) |
RF |
|
30199883 |
337 |
Alzheimer's Disease |
human |
an increase in K(+) intake |
PF |
|
26391254 |
338 |
Amyotrophic lateral sclerosis |
human |
an IQR increase of CO |
RF |
|
30622072 |
339 |
Amyotrophic lateral sclerosis |
human |
an IQR increase of PM10 |
RF |
|
30622072 |
340 |
Amyotrophic lateral sclerosis |
human |
an IQR increase of PM2.5 |
RF |
|
30622072 |
341 |
Amyotrophic lateral sclerosis |
human |
an IQR increase of SO2 |
RF |
|
30622072 |
342 |
Alzheimer's disease |
human |
anemia |
RF |
|
24419041 |
343 |
Alzheimer’s Disease |
human |
Anxiety |
RF |
Calculated by fixed effect model |
30339108 |
343 |
Alzheimer’s Disease |
human |
Anxiety |
RF |
Calculated by random effect model |
30339108 |
343 |
Alzheimer's Disease |
human |
Anxiety |
RF |
Model 1: Main effect unadjusted |
29077487 |
343 |
Alzheimer's Disease |
human |
Anxiety |
RF |
Model 2: Main effects adjusted for sex, education, age, and race. |
29077487 |
343 |
Alzheimer's Disease |
human |
Anxiety |
RF |
Model 3: Main effects adjusted for adjusted for sex, age, education, race, e4 carrier status |
29077487 |
343 |
Alzheimer's Disease |
human |
Anxiety |
RF |
Model 4: Main effects adjusted for adjusted for sex, age, education, race, e4 carrier status, the presence of hypertension and hypercholesterolemia |
29077487 |
343 |
Alzheimer's disease |
human |
anxiety |
RF |
people with mild cognitive impairment (MCI) |
21518614 |
343 |
Parkinson's Disease |
human |
Anxiety |
RF |
|
12784267 |
343 |
Alzheimer's disease |
human |
Anxiety |
RF |
Clinically significant anxiety,not subclinical anxiety |
30825716 |
344 |
Amyotrophic lateral sclerosis |
human |
Military work |
RF |
Adjusted for matching factors and socioeconomic status (SES) |
26583610 |
345 |
Lewy body dementia |
human |
Arterial hypertension (AH) |
RF |
|
20965516 |
346 |
Alzheimer’s Disease |
human |
Arthritis |
PF |
|
2146525 |
346 |
Amyotrophic lateral sclerosis |
human |
Arthritis |
PF |
|
27065942 |
347 |
Alzheimer’s Disease |
human |
Atherosclerotic heart disease |
PF |
after Hemodialysis Initiation |
30093374 |
348 |
Alzheimer's Disease |
human |
atrial fibrillation (AF) |
RF |
|
24825565 |
349 |
Tuberous sclerosis complex |
human |
autistic features |
RF |
|
28721058 |
350 |
Amyotrophic lateral sclerosis |
human |
Average daily adulthood PA(Physical Activity) |
RF |
|
26998882 |
351 |
Amyotrophic lateral sclerosis |
human |
Average daily PA(Physical Activity) in last 5–15 years |
RF |
|
26998882 |
352 |
Amyotrophic lateral sclerosis |
human |
AVM(arteriovenous malformation) |
RF |
all |
26260352 |
352 |
Amyotrophic lateral sclerosis |
human |
AVM(arteriovenous malformation) |
RF |
cerebral vessels |
26260352 |
353 |
Amyotrophic lateral sclerosis |
human |
Bank tellers |
RF |
worked or were unemployed at 1991 Italian census, and were still resident in Turin at the beginning of 1996 |
28201634 |
354 |
Alzheimer's Disease |
human |
beliefs about stress |
RF |
|
28605999 |
355 |
Alzheimer’s Disease |
human |
Benzene, toluene exposure |
RF |
|
7771442 |
356 |
progressive supranuclear palsy |
human |
beta-blocker use |
RF |
|
31420308 |
357 |
Alzheimer's disease |
human |
Better sleep consolidation attenuate |
PF |
in APOE e4 carriers |
24145819 |
358 |
Alzheimer's disease |
human |
Bilingualism |
PF |
|
30475769 |
359 |
Amyotrophic lateral sclerosis |
human |
blood levels of Copper (μg/dL) |
RF |
Adjusted for age, gender and race/ethnicity. |
27085208 |
360 |
Amyotrophic lateral sclerosis |
human |
blood levels of Manganese (μg/dL) |
RF |
Adjusted for age, gender and race/ethnicity. |
27085208 |
361 |
Amyotrophic lateral sclerosis |
human |
blood levels of Selenium (μg/dL) |
PF |
Adjusted for age, gender and race/ethnicity. |
27085208 |
361 |
Amyotrophic lateral sclerosis |
human |
blood levels of Selenium (μg/dL) |
PF |
Adjusted for age, gender and race/ethnicity. |
27085208 |
361 |
Amyotrophic lateral sclerosis |
human |
blood levels of Selenium (μg/dL) |
PF |
Adjusted for age, gender and race/ethnicity. |
27085208 |
361 |
Amyotrophic lateral sclerosis |
human |
blood levels of Selenium (μg/dL) |
PF |
Adjusted for age, gender and race/ethnicity. |
27085208 |
362 |
Amyotrophic lateral sclerosis |
human |
blood levels of Zinc (μg/dL) |
PF |
Adjusted for age, gender and race/ethnicity. |
27085208 |
362 |
Amyotrophic lateral sclerosis |
human |
blood levels of Zinc (μg/dL) |
PF |
Adjusted for age, gender and race/ethnicity. |
27085208 |
363 |
Alzheimer's Disease |
human |
blood pressure variability (BPV) |
RF |
|
28784823 |
364 |
Amyotrophic lateral sclerosis |
human |
BMI history |
RF |
OR controlled for age, sex, duration of school education, and smoking status |
28975435 |
364 |
Amyotrophic lateral sclerosis |
human |
BMI history |
RF |
OR controlled for age, sex, duration of school education, and smoking status |
28975435 |
364 |
Amyotrophic lateral sclerosis |
human |
BMI history |
RF |
OR controlled for age, sex, duration of school education, and smoking status |
28975435 |
364 |
Amyotrophic lateral sclerosis |
human |
BMI history |
PF |
OR controlled for age, sex, duration of school education, and smoking status |
28975435 |
365 |
Amyotrophic lateral sclerosis |
human |
BMI(Body Mass Index) |
RF |
Low BMI(Body Mass Index) |
31155341 |
366 |
Amyotrophic lateral sclerosis |
human |
Boat, sail, or kayak |
RF |
residents of New England or the bordering New York region at the time of enrollment |
28122372 |
367 |
Alzheimer’s Disease |
human |
Body mass index |
RF |
after Hemodialysis Initiation; <18.5 |
30093374 |
367 |
Alzheimer’s Disease |
human |
Body mass index |
RF |
after Hemodialysis Initiation; 18.5–25.0 |
30093374 |
367 |
Alzheimer’s Disease |
human |
Body mass index |
RF |
after Hemodialysis Initiation; 25.0–30.0 |
30093374 |
367 |
Alzheimer’s Disease |
human |
Body mass index |
RF |
extrinsic epigenetic age acceleration |
30167451 |
367 |
Alzheimer’s Disease |
human |
Body mass index |
RF |
intrinsic epigenetic age acceleration |
30167451 |
368 |
Alzheimer's disease |
human |
bone mineral density (BMD) |
RF |
low bone mineral density (BMD) |
21187587 |
369 |
Alzheimer's disease |
rabbit |
Caffeine |
PF |
even very low doses of caffeine might protect against sporadic AD |
20638472 |
369 |
Alzheimer's disease |
human |
Caffeine |
PF |
coffee drinking of 3-5 cups per day at midlife was associated with a decreased risk of dementia/AD by about 65% at late-life |
20182054 |
370 |
Parkinson's Disease |
human |
caffeine intake |
RF |
GRIN2A rs4998386 T allele;taking creatine who also have high levels of caffeine intake |
28320167 |
371 |
Tuberous sclerosis complex |
human |
calcification in the cerebral parenchyma |
RF |
|
29929111 |
372 |
Alzheimer’s Disease |
human |
Cancer |
PF |
after Hemodialysis Initiation |
30093374 |
372 |
Alzheimer's disease |
human |
Cancer |
PF |
|
30906403 |
372 |
Alzheimer's disease |
human |
Cancer |
PF |
Cancer History(Cancer survivors) |
28035936 |
373 |
Alzheimer's disease |
human |
Cardiorespiratory fitness (CRF) |
PF |
|
28293467 |
374 |
Alzheimer’s Disease |
human |
cardiovascular disease (CaVD) |
RF |
|
30149459 |
375 |
Alzheimer's Disease |
human |
carotid atherosclerosis |
RF |
|
28810593 |
376 |
Alzheimer’s Disease |
human |
Cataract |
PF |
|
2146525 |
377 |
Alzheimer’s Disease |
human |
cerebrovascular disease |
RF |
Cerebrovascular Alterations |
30355253 |
377 |
Alzheimer's Disease |
human |
cerebrovascular disease |
RF |
|
28806610 |
378 |
Alzheimer's disease |
human |
characteristics of anxiety |
RF |
people with mild cognitive impairment (MCI) |
21518614 |
379 |
Alzheimer’s Disease |
human |
childhood stress |
RF |
|
30020441 |
379 |
Alzheimer’s Disease |
human |
childhood stress |
RF |
adjusted for age, education, income and other covariates |
30020441 |
380 |
Parkinson's Disease |
human |
chronic exposure to metals |
RF |
|
9065542 |
381 |
Alzheimer's disease |
mice |
Chronic low-dose-rate ionising radiation |
RF |
chronic low-dose-rate radiation exposure (1 mGy/day or 20 mGy/day) |
27708245 |
382 |
Tourette Syndrome |
human |
chronic maternal anxiety |
RF |
mothers' chronic maternal anxiety affecting the offspring |
26174227 |
383 |
Alzheimer's Disease |
human |
chronic periodontitis (CP) |
RF |
10-year CP exposure |
28784164 |
384 |
Parkinson's Disease |
human |
chronic renal dysfunction |
RF |
Older adults |
31021467 |
385 |
Alzheimer's disease |
mice |
Chronic Sleep Deprivation(SD) |
RF |
|
26757041 |
386 |
Parkinson's Disease |
rat |
cinnarizine(a calcium antagonist that produces human parkinsonism) |
RF |
(a calcium antagonist that produces human parkinsonism) |
15993444 |
387 |
Amyotrophic lateral sclerosis |
mouse |
Circadian rhythm dysfunction (CRD) |
RF |
Transgenic mice overexpressing human SOD1 were obtained from the Nanjing Biomedical Research Institute of Nanjing University |
29740382 |
387 |
Parkinson's Disease |
rat |
Circadian rhythm dysfunction (CRD) |
RF |
|
27046648 |
388 |
Alzheimer's Disease |
human |
coffee consumption |
RF |
per one cup a day |
29212772 |
389 |
Alzheimer's Disease |
human |
cognitive impairment |
RF |
|
23254639 |
390 |
Alzheimer’s Disease |
human |
Congestive heart failure |
PF |
after Hemodialysis Initiation |
30093374 |
391 |
Alzheimer’s Disease |
human |
constipation |
RF |
colorectal cancer and AD have similar epidemiologic feature |
30323761 |
391 |
Parkinson's Disease |
human |
Constipation |
RF |
the relative risk was higher for men than for women |
27234704 |
391 |
Parkinson's Disease |
human |
Constipation |
RF |
|
27444575 |
392 |
Amyotrophic lateral sclerosis |
human |
construction work |
RF |
|
27124833 |
392 |
Amyotrophic Lateral Sclerosis |
human |
construction work |
RF |
|
19750102 |
393 |
Amyotrophic lateral sclerosis |
human |
COPD(chronic obstructive pulmonary disease) |
PF |
|
27065942 |
394 |
Lewy body dementia |
human |
Cortical thinning |
RF |
patients with idiopathic REM sleep behavior disorder (iRBD) |
31069252 |
395 |
Alzheimer's disease |
human |
covariant associated with social status |
RF |
|
26893902 |
396 |
Tourette Syndrome |
human |
culture level of parents |
RF |
lower culture level of parents |
20654033 |
397 |
Amyotrophic lateral sclerosis |
human |
current proximity to any agricultural land or specific crop type within 100m from residence |
RF |
Total agricultural land |
28851431 |
398 |
Amyotrophic lateral sclerosis |
human |
Defense NEC(Not Elsewhere Classified) |
RF |
Adjusted for matching factors and socioeconomic status (SES) |
26583610 |
399 |
Creutzfeldt-Jakob disease |
human |
Dementia in family |
RF |
|
3066847 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
clinically significant depressive symptoms at baseline |
26343475 |
400 |
Alzheimer’s Disease |
human |
Depression |
RF |
|
29606955 |
400 |
Alzheimer’s Disease |
human |
Depression |
RF |
fundamental shift in depression-related monoaminergic systems (including serotonin and noradrenaline) |
29685068 |
400 |
Alzheimer's Disease |
human |
depression |
RF |
|
28731429 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
|
25401488 |
400 |
Alzheimer's Disease |
human |
depression |
RF |
|
18603262 |
400 |
Lewy body dementia |
human |
depression |
RF |
|
30503177 |
400 |
Parkinson's Disease |
human |
Depression |
RF |
|
25995056 |
400 |
Parkinson's Disease |
human |
Depression |
RF |
|
24089392 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
clinician verified;Model 1: Main effect unadjusted |
29077487 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
clinician verified;Model 2: Main effects adjusted for sex, education, age, and race. |
29077487 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
clinician verified;Model 3: Main effects adjusted for adjusted for sex, age, education, race, e4 carrier status |
29077487 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
clinician verified;Model 4: Main effects adjusted for adjusted for sex, age, education, race, e4 carrier status, the presence of hypertension and hypercholesterolemia |
29077487 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
Model 1: Main effect unadjusted |
29077487 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
Model 2: Main effects adjusted for sex, education, age, and race. |
29077487 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
Model 3: Main effects adjusted for adjusted for sex, age, education, race, e4 carrier status |
29077487 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
Model 4: Main effects adjusted for adjusted for sex, age, education, race, e4 carrier status, the presence of hypertension and hypercholesterolemia |
29077487 |
400 |
Alzheimer’s Disease |
human |
Depression |
RF |
Depressive disorder in last 10 years |
2146525 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
|
28605999 |
400 |
Alzheimer's disease |
human |
Depression |
RF |
HAM:Hamilton Depression Rating Scale |
18327871 |
400 |
Alzheimer's disease |
mice |
Depression |
RF |
|
27837334 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
Late-onset MD(major episode) with DEDS;after adjustment by age, gender, marital status, education, cognitive impairment, executive function and stroke history |
22588687 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
Late-onset MDDIS(minor depressive disorders) with DEDS;after adjustment by age, gender, marital status, education, cognitive impairment, executive function and stroke history |
22588687 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
late-onset MD with DEDS |
22588687 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
late-onset MDDIS with DEDS |
22588687 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
unadjusted |
28560728 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
adjusteda without ε4 carrier status Hazard ratio |
28560728 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
adjusted with ε4 carrier status Hazard ratio |
28560728 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
personal history of depression |
24596166 |
400 |
Parkinson's Disease |
human |
Depression |
RF |
Previous history of depression |
21059511 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
recent depression last 2 years;unadjusted |
28560728 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
recent depression last 2 years;adjusteda without ε4 carrier status Hazard ratio |
28560728 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
recent depression last 2 years;adjusted with ε4 carrier status Hazard ratio |
28560728 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
recent depression last 2 years;adjusted with ε4 carrier status and AD Medication use Hazard ratio |
28560728 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
Model 1: Main effect unadjusted |
29077487 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
Model 2: Main effects adjusted for sex, education, age, and race. |
29077487 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
Model 3: Main effects adjusted for adjusted for sex, age, education, race, e4 carrier status |
29077487 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
Model 4: Main effects adjusted for adjusted for sex, age, education, race, e4 carrier status, the presence of hypertension and hypercholesterolemia |
29077487 |
400 |
Alzheimer's Disease |
human |
Depression |
RF |
Severe depression |
23791538 |
401 |
Alzheimer’s Disease |
human |
Diabetes |
RF |
|
29971140 |
401 |
Alzheimer’s Disease |
human |
Diabetes |
RF |
|
30103328 |
401 |
Alzheimer’s Disease |
human |
Diabetes |
RF |
after Hemodialysis Initiation |
30093374 |
401 |
Alzheimer's Disease |
human |
diabetes |
RF |
|
28806610 |
401 |
Alzheimer's disease |
human |
Diabetes |
RF |
|
28503814 |
401 |
Alzheimer's disease |
human |
diabetes |
RF |
people with mild cognitive impairment (MCI) |
21518614 |
401 |
Alzheimer's disease |
human |
Diabetes |
PF |
with APOE4 genotype in AD population |
18189240 |
401 |
Amyotrophic lateral sclerosis |
human |
Diabetes |
PF |
Unadjusted |
26030836 |
401 |
Amyotrophic lateral sclerosis |
human |
Diabetes |
PF |
Adjusted for socioeconomic status, prior chronic obstructive pulmonary disease, marital status, and residence at amyotrophic lateral sclerosis diagnosis. |
26030836 |
401 |
Amyotrophic lateral sclerosis |
human |
Diabetes |
PF |
Adjusted for socioeconomic status, prior chronic obstructive pulmonary disease, marital status, and residence at amyotrophic lateral sclerosis diagnosis, with diabetes and obesity simultaneously included in the model. |
26030836 |
401 |
Parkinson's Disease |
human |
Diabetes |
RF |
|
19467671 |
401 |
Parkinson's Disease |
human |
Diabetes |
RF |
|
19467671 |
401 |
Parkinson's Disease |
human |
Diabetes |
RF |
|
24955210 |
401 |
Alzheimer’s Disease |
human |
Diabetes |
RF |
|
30149459 |
401 |
Alzheimer’s Disease |
human |
Diabetes |
RF |
|
29606955 |
401 |
Alzheimer’s Disease |
human |
Diabetes |
RF |
|
7473847 |
401 |
Alzheimer’s Disease |
human |
Diabetes |
RF |
|
15148141 |
401 |
Alzheimer's Disease |
human |
Diabetes |
RF |
|
26495049 |
401 |
Frontotemporal Dementia |
human |
Diabetes |
RF |
|
24995127 |
401 |
Lewy body dementia |
human |
Diabetes |
RF |
|
29971140 |
401 |
Alzheimer's disease |
human |
Diabetes |
RF |
|
24489845 |
401 |
Alzheimer's disease |
human |
Diabetes |
RF |
people with mild memory impairment/no dementia (MMI/ND) |
21205364 |
402 |
Alzheimer's Disease |
human |
dieldrin |
RF |
|
22904031 |
403 |
Alzheimer's Disease |
human |
Dietary AGEs(dietary advanced glycation end products) |
RF |
|
25633677 |
404 |
Amyotrophic Lateral Sclerosis |
human |
Dietary habits:Cold cuts |
RF |
all cases |
19922125 |
404 |
Amyotrophic Lateral Sclerosis |
human |
Dietary habits:Cold cuts |
RF |
Bulbar cases |
19922125 |
405 |
Creutzfeldt-Jakob disease |
human |
Dietary Risk |
RF |
Hot Dogs |
24977122 |
405 |
Creutzfeldt-Jakob disease |
human |
Dietary Risk |
RF |
Sausage |
24977122 |
405 |
Creutzfeldt-Jakob disease |
human |
Dietary Risk |
RF |
Pepperoni |
24977122 |
405 |
Creutzfeldt-Jakob disease |
human |
Dietary Risk |
RF |
Kielbasa |
24977122 |
405 |
Creutzfeldt-Jakob disease |
human |
Dietary Risk |
RF |
“Other” Canned Meat |
24977122 |
405 |
Creutzfeldt-Jakob disease |
human |
Dietary Risk |
RF |
kidneys,ever |
19144172 |
405 |
Creutzfeldt-Jakob disease |
human |
Dietary Risk |
RF |
consumption of raw meat |
9660576 |
405 |
Creutzfeldt-Jakob disease |
human |
Dietary Risk |
RF |
consumption of brain |
9660576 |
405 |
Alzheimer’s Disease |
human |
Dietary Risk |
PF |
Dietary sources that contain high amounts of DHA in phospholipid form |
30289748 |
406 |
Alzheimer's disease |
mice |
dietary sugar or sucrose |
RF |
controlling the consumption of sugar-sweetened beverages may be an effective way to curtail the risk of developing AD |
17942401 |
407 |
Parkinson's Disease |
human |
Dietary Vitamin E |
PF |
|
30863359 |
408 |
Parkinson's Disease |
human |
dipstick-positive proteinuria |
RF |
Older adults |
31021467 |
409 |
Alzheimer’s Disease |
human |
Disorders in a 1st-degree relative |
RF |
Dementia |
2146525 |
409 |
Alzheimer’s Disease |
human |
Disorders in a 1st-degree relative |
RF |
Probable AD |
2146525 |
409 |
Alzheimer’s Disease |
human |
Disorders in a 1st-degree relative |
RF |
Down’s syndrome |
2146525 |
409 |
Alzheimer’s Disease |
human |
Disorders in a 1st-degree relative |
PF |
Thyroid disorders |
2146525 |
410 |
Alzheimer’s Disease |
human |
Dispersion and Disengaged Lifestyle |
RF |
|
31162439 |
411 |
Alzheimer's disease |
human |
disseminated mycoses |
RF |
|
24452965 |
412 |
Amyotrophic lateral sclerosis |
human |
Distance agricultural areas |
RF |
100m300m |
29852480 |
413 |
Alzheimer's disease |
human |
dread fullness |
RF |
people with mild cognitive impairment (MCI) |
21518614 |
414 |
Alzheimer's disease |
human |
Drinking |
RF |
Daily drinking |
21187587 |
414 |
Alzheimer’s Disease |
human |
Drinking |
PF |
|
12707449 |
414 |
Amyotrophic lateral sclerosis |
human |
Drinking |
RF |
|
31155341 |
414 |
Amyotrophic lateral sclerosis |
human |
Drinking |
PF |
|
22791740 |
414 |
Creutzfeldt-Jakob disease |
human |
Drinking |
PF |
Current alcohol |
3066847 |
414 |
Frontotemporal Lobar Degeneration |
human |
Drinking |
PF |
|
28946566 |
414 |
Frontotemporal Lobar Degeneration |
human |
Drinking |
PF |
Current alcohol consumers |
28946566 |
415 |
Parkinson's Disease |
human |
Drug-induced parkinsonism |
RF |
|
9703296 |
415 |
Parkinson's Disease |
human |
Drug-induced parkinsonism |
RF |
|
9703296 |
416 |
Creutzfeldt-Jakob disease |
human |
Duration (years) lived or worked on farm or market garden |
RF |
10-19 years |
10073510 |
416 |
Creutzfeldt-Jakob disease |
human |
Duration (years) lived or worked on farm or market garden |
RF |
>=20 years |
10073510 |
417 |
Frontotemporal Lobar Degeneration |
human |
duration of exposure |
PF |
for every 5 years of exposure increase |
28946566 |
418 |
Parkinson's Disease |
human |
duration of exposure to levodopa |
RF |
|
23836370 |
418 |
Parkinson's Disease |
human |
duration of exposure to levodopa |
RF |
|
23836370 |
419 |
Amyotrophic lateral sclerosis |
human |
Duration of OCP(oral contraceptive) use (per year) |
PF |
female |
28835399 |
420 |
Amyotrophic lateral sclerosis |
human |
Duration of physical activity |
PF |
|
24706338 |
420 |
Amyotrophic lateral sclerosis |
human |
Duration of physical activity |
PF |
Significant adjusted OR |
24706338 |
420 |
Amyotrophic lateral sclerosis |
human |
Duration of physical activity |
PF |
|
24706338 |
420 |
Amyotrophic lateral sclerosis |
human |
Duration of physical activity |
PF |
|
24706338 |
420 |
Amyotrophic lateral sclerosis |
human |
Duration of physical activity |
PF |
|
24706338 |
421 |
Amyotrophic lateral sclerosis |
human |
Duration of sport activity |
PF |
|
24706338 |
421 |
Amyotrophic lateral sclerosis |
human |
Duration of sport activity |
PF |
Significant adjusted OR |
24706338 |
421 |
Amyotrophic lateral sclerosis |
human |
Duration of sport activity |
PF |
|
24706338 |
421 |
Amyotrophic lateral sclerosis |
human |
Duration of sport activity |
PF |
|
24706338 |
422 |
Alzheimer's disease |
human |
dyslipidemia |
RF |
|
30894904 |
423 |
Creutzfeldt-Jakob disease |
human |
Ear piercing |
RF |
females only |
12196646 |
424 |
Tuberous sclerosis complex |
human |
Early-onset and severe epilepsy |
RF |
in the first 2 years of life |
31538337 |
425 |
Alzheimer's Disease |
human |
education |
PF |
a higher number of school years |
25624416 |
425 |
Alzheimer's Disease |
human |
education |
PF |
|
20016220 |
425 |
Alzheimer's disease |
human |
education |
RF |
|
31058682 |
425 |
Multiple System Atrophy |
human |
education |
RF |
≤ 12 years |
18307243 |
425 |
Multiple System Atrophy |
human |
education |
RF |
≤ 12 years;In Paris |
18307243 |
425 |
Multiple System Atrophy |
human |
education |
RF |
≤ 12 years;In another French region |
18307243 |
425 |
progressive supranuclear palsy |
human |
education |
PF |
|
29973911 |
425 |
Amyotrophic lateral sclerosis |
human |
education |
PF |
Exposure in the last 30 years |
24979055 |
425 |
Amyotrophic lateral sclerosis |
human |
education |
PF |
Exposure in the last 10 years |
24979055 |
425 |
Amyotrophic lateral sclerosis |
human |
education |
PF |
Exposure in the period from 30 years ago to 10 years ago |
24979055 |
425 |
Amyotrophic lateral sclerosis |
human |
education |
PF |
Continuous Exposure in the last 30 years |
24979055 |
425 |
progressive supranuclear palsy |
human |
education |
PF |
|
31420308 |
425 |
progressive supranuclear palsy |
human |
education |
PF |
in the multi-variate analysis |
31420308 |
425 |
Alzheimer's disease |
human |
education |
PF |
in PSEN1 E280A mutation carriers |
26902171 |
425 |
Amyotrophic Lateral Sclerosis |
human |
education |
RF |
Elementary school(Crude OR) |
17923612 |
425 |
Amyotrophic lateral sclerosis |
human |
education |
PF |
Exposure Ever Happened in Entire Occupational History |
27159543 |
425 |
Amyotrophic lateral sclerosis |
human |
education |
PF |
Exposure Ever Happened in Last 10 years |
27159543 |
425 |
Amyotrophic lateral sclerosis |
human |
education |
PF |
Exposure Ever Happened 10-30 years Ago |
27159543 |
425 |
Amyotrophic lateral sclerosis |
human |
education |
PF |
Exposure Ever Happened >30 years Ago |
27159543 |
425 |
Alzheimer's disease |
human |
education |
PF |
people with mild cognitive impairment (MCI) |
21518614 |
425 |
Amyotrophic Lateral Sclerosis |
human |
education |
RF |
|
31011473 |
425 |
Alzheimer's Disease |
human |
education |
PF |
per year of education completed |
29212772 |
425 |
Alzheimer's Disease |
human |
education |
PF |
per unit higher log odds of having completed college/university |
29212772 |
425 |
Amyotrophic lateral sclerosis |
human |
education |
PF |
Longer duration of education |
31155341 |
425 |
Tourette Syndrome |
human |
education |
RF |
low family education |
20654033 |
425 |
Tourette Syndrome |
human |
education |
RF |
low level of parental education |
22738448 |
425 |
Alzheimer's disease |
human |
education |
RF |
lower education |
18446027 |
425 |
Alzheimer's disease |
human |
education |
RF |
Lower levels of education |
30425786 |
425 |
Lewy body dementia |
human |
education |
RF |
fewer than 5 years of formal education |
27264344 |
425 |
Alzheimer's Disease |
human |
education |
RF |
Lack of formal education |
25401488 |
425 |
Alzheimer's Disease |
human |
education |
RF |
Low Education |
26495049 |
425 |
Alzheimer’s Disease |
human |
education |
RF |
Low educational attainent |
29606955 |
426 |
Amyotrophic lateral sclerosis |
human |
Electric current injuries |
RF |
|
27124833 |
426 |
Amyotrophic lateral sclerosis |
human |
Electric current injuries |
RF |
|
29681882 |
427 |
Alzheimer’s Disease |
human |
Employment status |
PF |
after Hemodialysis Initiation; Employed |
30093374 |
427 |
Alzheimer’s Disease |
human |
Employment status |
RF |
after Hemodialysis Initiation; Other |
30093374 |
428 |
Alzheimer's Disease |
human |
endothelial dysfunction |
RF |
specifically loss of endothelial NO |
23745722 |
429 |
Alzheimer's disease |
human |
environmental exposure to cadmium |
RF |
high cadmium levels (>0.6 μg/L) |
27301955 |
430 |
Amyotrophic lateral sclerosis |
human |
Environmental toxins |
RF |
organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs) and brominated flame retardants (BFRs) |
27231185 |
431 |
Tuberous sclerosis complex |
human |
epilepsy |
RF |
|
26631248 |
432 |
Amyotrophic lateral sclerosis |
human |
Ever worked in US Armed Forces |
RF |
Exposure Ever Happened 10-30 years Ago |
27159543 |
433 |
Alzheimer's disease |
mice |
excess zinc exposure |
RF |
|
21179415 |
434 |
Parkinson's Disease |
human |
exercise |
PF |
|
12140099 |
434 |
Parkinson's Disease |
human |
exercise |
PF |
|
12140099 |
435 |
Alzheimer's Disease |
human |
experienced appreciable weight loss |
RF |
|
18835864 |
436 |
Chronic Traumatic Encephalopathy |
human |
Exposure to contact sports |
RF |
|
26518018 |
437 |
Parkinson's Disease |
human |
exposure to hydrocarbon solvents |
RF |
|
10980731 |
438 |
Amyotrophic lateral sclerosis |
human |
Exposure to Lead |
RF |
residents of New England or the bordering New York region at the time of enrollment |
28122372 |
438 |
Amyotrophic lateral sclerosis |
human |
Exposure to Lead |
RF |
residents of New England or the bordering New York region at the time of enrollment |
28122372 |
438 |
Alzheimer's Disease |
human |
Exposure to Lead |
RF |
Cigarette smoking |
29089568 |
438 |
Amyotrophic Lateral Sclerosis |
human |
Exposure to Lead |
RF |
|
19750102 |
438 |
Amyotrophic Lateral Sclerosis |
human |
Exposure to Lead |
RF |
Ever had a job with lead exposure |
16909025 |
438 |
Amyotrophic Lateral Sclerosis |
human |
Exposure to Lead |
RF |
Lifetime days of lead exposure:2,000+ |
16909025 |
439 |
Parkinson's Disease |
human |
exposure to metals |
RF |
high reported industrial release of copper or manganese |
20959505 |
439 |
Parkinson's Disease |
human |
exposure to metals |
RF |
high reported industrial release of copper or manganese |
20959505 |
440 |
Alzheimer’s Disease |
human |
Exposure to N2O |
RF |
|
29991368 |
441 |
Parkinson's Disease |
human |
Exposure to neuroleptic drugs |
RF |
|
10047927 |
442 |
progressive supranuclear palsy |
human |
exposure to organic solvents |
RF |
self-reporting exposure to organic solvents |
26854325 |
443 |
Parkinson's Disease |
human |
exposure to Pb |
RF |
|
17185278 |
444 |
Amyotrophic lateral sclerosis |
human |
Exposure to Pesticide |
RF |
residents of New England or the bordering New York region at the time of enrollment |
28122372 |
444 |
Amyotrophic lateral sclerosis |
human |
Exposure to Pesticide |
RF |
residents of New England or the bordering New York region at the time of enrollment |
28122372 |
444 |
Parkinson's Disease |
human |
Exposure to Pesticide |
RF |
|
11437458 |
444 |
Amyotrophic Lateral Sclerosis |
human |
Exposure to Pesticide |
RF |
In a conditional logistic regression model |
20847462 |
444 |
Parkinson's Disease |
human |
Exposure to Pesticide |
RF |
|
21059511 |
444 |
Parkinson's Disease |
rat |
Exposure to Pesticide |
RF |
|
22563483 |
444 |
progressive supranuclear palsy |
human |
Exposure to Pesticide |
RF |
self-reporting exposure to pesticides |
26854325 |
445 |
Alzheimer’s Disease |
human |
Exposure to PM2.5 |
RF |
|
29935448 |
446 |
Amyotrophic lateral sclerosis |
human |
Exposure to Solvents |
RF |
residents of New England or the bordering New York region at the time of enrollment |
28122372 |
447 |
Amyotrophic lateral sclerosis |
human |
Exposure to the highest quartiles of PM10 |
RF |
|
30622072 |
448 |
Amyotrophic lateral sclerosis |
human |
Exposure to the highest quartiles of PM2.5 |
RF |
|
30622072 |
449 |
Parkinson's Disease |
human |
exposure to trichloroethylene (TCE) |
RF |
|
22083847 |
450 |
Amyotrophic lateral sclerosis |
human |
Exposure to welding or soldering materials |
RF |
|
27124833 |
451 |
Parkinson's Disease |
human |
well water ingestion |
RF |
|
1584237 |
452 |
Frontotemporal Lobar Degeneration |
human |
Familial aggregation |
RF |
first-degree relatives (parents and siblings) of frontotemporal dementia (FTD) patients |
9633692 |
453 |
Tourette Syndrome |
human |
family conflict |
RF |
|
22738448 |
453 |
Tourette Syndrome |
human |
family conflict |
RF |
|
20654033 |
454 |
Tourette Syndrome |
human |
family control and fetal anoxia |
RF |
|
22738448 |
455 |
Tourette Syndrome |
human |
family history |
RF |
|
22738448 |
456 |
Alzheimer's Disease |
human |
family history of cardiovascular diseases |
RF |
|
24596166 |
457 |
Lewy body dementia |
human |
Family history of dementia |
RF |
|
16801670 |
458 |
Alzheimer's disease |
human |
Family history of dementia (FH) |
RF |
|
26531229 |
459 |
Alzheimer's disease |
human |
family history of dementia (within third-degree relatives) |
RF |
people with mild memory impairment/no dementia (MMI/ND) |
21205364 |
460 |
Alzheimer's disease |
human |
farming |
PF |
|
31239120 |
460 |
Alzheimer's disease |
human |
farming |
PF |
|
31239120 |
460 |
Parkinson's Disease |
human |
farming |
RF |
|
11437458 |
460 |
Multiple System Atrophy |
human |
farming |
RF |
1-20 years |
27670212 |
460 |
Multiple System Atrophy |
human |
farming |
RF |
1-20 years |
27670212 |
460 |
Multiple System Atrophy |
human |
farming |
RF |
>20 years |
27670212 |
460 |
Multiple System Atrophy |
human |
farming |
RF |
>20 years |
27670212 |
460 |
Multiple System Atrophy |
human |
farming |
RF |
MSA cases vs. hospital controls |
15382209 |
460 |
Multiple System Atrophy |
human |
farming |
RF |
MSA cases vs. hospital controls |
15382209 |
460 |
Multiple System Atrophy |
human |
farming |
RF |
MSA cases vs. population controls |
15382209 |
460 |
Multiple System Atrophy |
human |
farming |
RF |
MSA cases vs. population controls |
15382209 |
460 |
Multiple System Atrophy |
human |
farming |
RF |
MSA cases vs. population controls;>20 years |
15382209 |
460 |
Multiple System Atrophy |
human |
farming |
RF |
MSA cases vs. population controls;>20 years |
15382209 |
315 |
Alzheimer's Disease |
human |
Obesity |
RF |
being obese (BMI ≥30) at age 30, 40, or 45 years and jointly centrally obese (waist circumference ≥80th percentile) at age 30, 35, or 50 years |
18835864 |
315 |
Parkinson's Disease |
human |
Obesity |
RF |
|
24955210 |
461 |
Tourette Syndrome |
human |
Febrile convulsions(FC) |
RF |
|
24907027 |
462 |
Creutzfeldt-Jakob disease |
human |
Ferret contact |
RF |
|
3066847 |
463 |
Amyotrophic Lateral Sclerosis |
human |
Fire fighting occupations |
RF |
|
20698805 |
463 |
Amyotrophic Lateral Sclerosis |
human |
Fire fighting occupations |
RF |
|
20698805 |
464 |
Tourette Syndrome |
human |
first-degree relatives |
RF |
|
26083307 |
464 |
Frontotemporal Dementia |
human |
first-degree relatives |
RF |
First-degree relatives(parents) |
9633692 |
465 |
Alzheimer's Disease |
human |
Formaldehyde (FA) |
RF |
|
24766729 |
466 |
Amyotrophic lateral sclerosis |
human |
Fractures |
RF |
all |
28316249 |
466 |
Amyotrophic lateral sclerosis |
human |
Fractures |
RF |
osteoporotic |
28316249 |
466 |
Amyotrophic lateral sclerosis |
human |
Fractures |
RF |
non-osteoporotic |
28316249 |
466 |
Amyotrophic lateral sclerosis |
human |
Fractures |
RF |
traumatic |
28316249 |
466 |
Amyotrophic lateral sclerosis |
human |
Fractures |
RF |
non-traumatic |
28316249 |
467 |
Creutzfeldt-Jakob disease |
human |
Frequent exposure |
RF |
frequent exposure to leather products |
9660576 |
467 |
Creutzfeldt-Jakob disease |
human |
Frequent exposure |
RF |
exposure to fertiliser consisting of hoofs and horns |
9660576 |
468 |
Amyotrophic lateral sclerosis |
human |
Fungal infection |
RF |
|
25892962 |
469 |
Alzheimer's Disease |
human |
Gender |
RF |
|
28806610 |
469 |
Alzheimer's Disease |
human |
Gender |
RF |
|
25624416 |
469 |
Alzheimer's Disease |
human |
Gender |
RF |
|
20016220 |
469 |
Alzheimer's disease |
human |
Gender |
RF |
|
27105335 |
469 |
Alzheimer's disease |
human |
Gender |
RF |
|
24489845 |
469 |
Alzheimer's disease |
human |
Gender |
RF |
|
22526079 |
469 |
Alzheimer’s Disease |
human |
Gender |
RF |
after Hemodialysis Initiation |
30093374 |
469 |
Amyotrophic lateral sclerosis |
human |
Gender |
PF |
|
27065942 |
469 |
Parkinson's Disease |
human |
gender |
RF |
|
20111594 |
470 |
Amyotrophic lateral sclerosis |
human |
General practitioners |
RF |
worked or were unemployed at 1991 Italian census, and were still resident in Turin at the beginning of 1996 |
28201634 |
471 |
Parkinson's Disease |
human |
glyphosate exposure |
RF |
|
30799335 |
472 |
progressive supranuclear palsy |
human |
have worked in transportation |
RF |
|
26854325 |
473 |
Alzheimer's disease |
human |
Having a first-degree relative or a parent with dementia |
RF |
|
26531229 |
474 |
Amyotrophic Lateral Sclerosis |
human |
having a past history of CS/SSM |
RF |
|
17538776 |
475 |
Amyotrophic Lateral Sclerosis |
human |
having surgical treatment for CS/SSM |
RF |
|
17538776 |
476 |
Lewy body dementia |
human |
Having three metabolic risk factors |
RF |
|
29971140 |
477 |
Alzheimer’s Disease |
human |
head circumference (HC) |
RF |
within the lowest quintile of HC for women |
9222166 |
478 |
Amyotrophic Lateral Sclerosis |
human |
Head injury |
RF |
all cases |
19922125 |
478 |
Amyotrophic Lateral Sclerosis |
human |
Head injury |
RF |
Bulbar cases |
19922125 |
478 |
Amyotrophic Lateral Sclerosis |
human |
head injury |
RF |
Age at last injury (years)≥29 |
20129626 |
478 |
Amyotrophic Lateral Sclerosis |
human |
head injury |
RF |
Years between last injury and reference date <=24 years |
20129626 |
478 |
Amyotrophic Lateral Sclerosis |
human |
head injury |
RF |
Years between last injury and reference date <=15 years |
20129626 |
478 |
Alzheimer’s Disease |
human |
Head injury |
RF |
|
10746604 |
478 |
Alzheimer’s Disease |
human |
Head injury |
RF |
|
12707449 |
478 |
Alzheimer’s Disease |
human |
Head injury |
RF |
|
12707449 |
478 |
Parkinson's Disease |
human |
head injury |
RF |
early in life |
25603768 |
478 |
Parkinson's Disease |
human |
head injury |
RF |
|
12140099 |
478 |
Amyotrophic lateral sclerosis |
human |
head injury |
RF |
|
31155341 |
478 |
Amyotrophic lateral sclerosis |
human |
head injury |
RF |
2+ Trauma |
29063790 |
478 |
Amyotrophic lateral sclerosis |
human |
head injury |
RF |
|
25059395 |
478 |
Frontotemporal Dementia |
human |
head injury |
RF |
|
14617722 |
478 |
Parkinson's Disease |
human |
head injury |
RF |
|
28748275 |
478 |
Amyotrophic lateral sclerosis |
human |
head injury |
RF |
Head trauma leading to functional disability |
29063790 |
479 |
Alzheimer's disease |
human |
Healthy diet |
PF |
in late life |
22163237 |
480 |
Frontotemporal Dementia |
human |
heart disease |
PF |
|
22465176 |
480 |
Frontotemporal Lobar Degeneration |
human |
heart disease |
PF |
|
22465176 |
481 |
Amyotrophic Lateral Sclerosis |
human |
heavy metals |
RF |
|
6538286 |
482 |
Amyotrophic lateral sclerosis |
human |
Heavy metals (lead) |
RF |
|
29681882 |
483 |
Alzheimer's disease |
|
Heavy metals toxicity:Cadmium (Cd) |
RF |
|
24557150 |
484 |
Parkinson's Disease |
human |
Hepatitis C virus(HCV) |
RF |
|
26701382 |
484 |
Parkinson's Disease |
human |
Hepatitis C virus(HCV) |
RF |
|
25608223 |
484 |
Parkinson's Disease |
human |
Hepatitis C virus(HCV) |
RF |
|
30710864 |
485 |
Multiple System Atrophy |
human |
Herbal medications |
RF |
|
20623770 |
485 |
Multiple System Atrophy |
human |
Herbal medications |
RF |
|
20623770 |
486 |
Amyotrophic Lateral Sclerosis |
human |
Herbicides/Pesticides |
RF |
with the total SALS group |
16946624 |
486 |
Amyotrophic Lateral Sclerosis |
human |
Herbicides/Pesticides |
RF |
with male SALS patients |
16946624 |
487 |
Creutzfeldt-Jakob disease |
human |
hGH(human cadaver-sourced growth hormone) treatment |
RF |
|
30045957 |
487 |
Creutzfeldt-Jakob disease |
human |
hGH(human cadaver-sourced growth hormone) treatment |
RF |
Proportion of doses risk category 1 (batches 1, 2, 3, 4, 7, 21, 26) |
30045957 |
487 |
Creutzfeldt-Jakob disease |
human |
hGH(human cadaver-sourced growth hormone) treatment |
RF |
Proportion of doses risk category 2 (batches 10, 12, 13, 18, 24) |
30045957 |
487 |
Creutzfeldt-Jakob disease |
human |
hGH(human cadaver-sourced growth hormone) treatment |
RF |
Proportion of doses risk category 3 (batches 5, 6, 8, 9, 11, 14, 15, 16, 17, 19, 20, 22, 23, 25, 27) |
30045957 |
488 |
Alzheimer’s Disease |
human |
High blood pressure |
RF |
intrinsic epigenetic age acceleration |
30167451 |
489 |
Alzheimer's Disease |
human |
High consumption of aluminum |
RF |
|
19064650 |
490 |
progressive supranuclear palsy |
human |
high exposure to highly stressful events |
RF |
|
28409749 |
491 |
Alzheimer's disease |
human |
High occupational attainment |
RF |
mild cognitive impairment(MCI) patient |
27662289 |
491 |
Alzheimer's disease |
human |
High occupational attainment |
PF |
|
27662289 |
492 |
Tuberous sclerosis complex |
human |
high tuber burden |
RF |
|
28721058 |
493 |
Alzheimer's disease |
human |
higher age among senior citizens in urban communities |
RF |
|
31286894 |
494 |
Alzheimer's Disease |
human |
higher body mass index |
RF |
|
24596166 |
495 |
Alzheimer's Disease |
human |
higher CDR-SB scores |
RF |
in male |
26343475 |
496 |
Alzheimer's disease |
human |
Higher leptin level |
PF |
|
21187587 |
497 |
Alzheimer's Disease |
human |
higher levels of estrogen exposure |
RF |
|
24968011 |
498 |
Alzheimer's Disease |
human |
higher levels of prenatal testosterone exposure |
RF |
|
24968011 |
499 |
progressive supranuclear palsy |
human |
higher number of years of drinking well water |
RF |
|
26854325 |
500 |
Alzheimer's disease |
human |
history of depressive episodes |
RF |
|
18446027 |
501 |
Tuberous sclerosis complex |
human |
history of infantile spasm (epileptic spasms) |
RF |
|
28721058 |
502 |
Creutzfeldt-Jakob disease |
human |
human growth hormone extract |
RF |
received human growth hormone extract for various period of time (mean +/- SD, 2.9 years) |
8797466 |
503 |
Alzheimer's disease |
human |
Hypercholesterolemia |
RF |
|
27921357 |
503 |
Amyotrophic lateral sclerosis |
human |
Hypercholesterolemia |
PF |
|
25059395 |
504 |
Alzheimer's Disease |
human |
hyperhomocysteinemia |
RF |
|
24656904 |
504 |
Alzheimer's disease |
human |
Hyperhomocysteinemia |
RF |
|
23833960 |
505 |
Alzheimer's disease |
human |
hyperlipidemia |
RF |
people with mild cognitive impairment (MCI) |
21518614 |
505 |
Alzheimer’s Disease |
human |
hyperlipidemia |
RF |
|
29971140 |
505 |
Alzheimer's Disease |
human |
hyperlipidemia |
RF |
|
28806610 |
505 |
Amyotrophic lateral sclerosis |
human |
Hyperlipidemia |
PF |
|
27065942 |
505 |
Amyotrophic lateral sclerosis |
human |
Hyperlipidemia |
RF |
|
30723964 |
505 |
Lewy body dementia |
human |
Hyperlipidemia |
RF |
|
29971140 |
506 |
Alzheimer's Disease |
human |
hypertension |
RF |
|
25624416 |
506 |
Amyotrophic lateral sclerosis |
human |
Hypertension |
PF |
|
31155341 |
506 |
Alzheimer’s Disease |
human |
hypertension |
RF |
|
29971140 |
506 |
Alzheimer’s Disease |
human |
hypertension |
RF |
|
30149459 |
506 |
Alzheimer’s Disease |
human |
Hypertension |
RF |
after Hemodialysis Initiation |
30093374 |
506 |
Alzheimer’s Disease |
human |
hypertension |
RF |
|
7473847 |
506 |
Alzheimer's Disease |
human |
hypertension |
RF |
|
20016220 |
506 |
Alzheimer's disease |
human |
hypertension |
RF |
|
30894904 |
506 |
Alzheimer's disease |
human |
hypertension |
RF |
|
24489845 |
506 |
Alzheimer's disease |
human |
hypertension |
RF |
people with mild cognitive impairment (MCI) |
21518614 |
506 |
Amyotrophic lateral sclerosis |
human |
Hypertension |
PF |
|
27065942 |
506 |
Lewy body dementia |
human |
hypertension |
RF |
|
29971140 |
506 |
progressive supranuclear palsy |
human |
hypertension |
RF |
|
31420308 |
506 |
progressive supranuclear palsy |
human |
hypertension |
RF |
in the multi-variate analysis |
31420308 |
506 |
Parkinson's Disease |
human |
Hypertension |
RF |
|
9778597 |
506 |
Alzheimer’s Disease |
human |
hypertension |
RF |
|
29606955 |
506 |
Alzheimer's Disease |
human |
hypertension |
RF |
|
26495049 |
507 |
Alzheimer’s Disease |
human |
hypertension and diabetes |
RF |
|
29971140 |
508 |
Alzheimer’s Disease |
human |
hypertension and hyperlipidemia |
RF |
|
29971140 |
509 |
Alzheimer’s Disease |
human |
hypertension, diabetes and hyperlipidemia |
RF |
|
29971140 |
510 |
Alzheimer's disease |
human |
hypertensive |
RF |
|
18288934 |
511 |
Parkinson's Disease |
human |
Idiopathic rapid eye movement sleep behaviour disorde |
RF |
|
19843648 |
512 |
Alzheimer’s Disease |
human |
Illiteracy |
RF |
< 1 year at school |
12212789 |
512 |
Alzheimer's Disease |
human |
Illiteracy |
RF |
|
25401488 |
513 |
Amyotrophic lateral sclerosis |
human |
Immunosuppressive drugs |
PF |
|
25059395 |
514 |
Alzheimer's disease |
human |
Improving cardiovascular functions |
PF |
mean velocity of the BA |
28505975 |
514 |
Alzheimer's disease |
human |
Improving cardiovascular functions |
PF |
mean velocity of the LTICA |
28505975 |
514 |
Alzheimer's disease |
human |
Improving cardiovascular functions |
PF |
Ejection fraction |
28505975 |
515 |
Alzheimer’s Disease |
human |
Inability to ambulate |
RF |
after Hemodialysis Initiation |
30093374 |
516 |
Amyotrophic lateral sclerosis |
human |
industrial chemicals |
RF |
residents of New England or the bordering New York region at the time of enrollment |
28122372 |
516 |
Amyotrophic lateral sclerosis |
human |
industrial chemicals |
RF |
residents of New England or the bordering New York region at the time of enrollment |
28122372 |
517 |
Amyotrophic lateral sclerosis |
human |
Industry in accommodation or food services |
PF |
Exposure Ever Happened in Entire Occupational History |
27159543 |
517 |
Amyotrophic lateral sclerosis |
human |
Industry in accommodation or food services |
PF |
Exposure Ever Happened >30 years Ago |
27159543 |
518 |
Amyotrophic lateral sclerosis |
human |
Industry in health care or social assistance |
PF |
Exposure Ever Happened in Entire Occupational History |
27159543 |
519 |
Amyotrophic lateral sclerosis |
human |
Industry in ublic administration |
PF |
Exposure Ever Happened in Entire Occupational History |
27159543 |
519 |
Amyotrophic lateral sclerosis |
human |
Industry in ublic administration |
PF |
Exposure Ever Happened 10-30 years Ago |
27159543 |
520 |
Tuberous sclerosis complex |
human |
infantile spams |
RF |
|
26631248 |
521 |
Parkinson's Disease |
human |
infection |
RF |
|
30632012 |
522 |
Alzheimer's Disease |
human |
infectious burden:C. pneumoniae |
RF |
|
24910016 |
523 |
Alzheimer's Disease |
human |
infectious burden:cytomegalovirus (CMV) |
RF |
|
24910016 |
524 |
Amyotrophic Lateral Sclerosis |
human |
inhalation of BMAA, DAB, and other aerosolized cyanotoxins |
RF |
|
19929742 |
525 |
Alzheimer’s Disease |
human |
institutionalization |
RF |
after Hemodialysis Initiation |
30093374 |
526 |
Alzheimer's Disease |
human |
Insulin resistance (IR) |
RF |
|
20031276 |
526 |
Alzheimer's disease |
human |
insulin resistance (IR) |
RF |
|
27079723 |
527 |
Alzheimer's disease |
human |
intellectual work |
PF |
people with mild cognitive impairment (MCI) |
21518614 |
528 |
Alzheimer's disease |
human |
introvert characteristics |
RF |
people with mild cognitive impairment (MCI) |
21518614 |
529 |
Alzheimer's Disease |
human |
ionizing radiation |
RF |
|
28671130 |
530 |
Alzheimer’s Disease |
human |
Job description only |
RF |
Exposure to printing/printer's ink, coal tar/creosote, oils, glues/resins/waxes, rubber production, or paints. |
7771442 |
531 |
Alzheimer’s Disease |
human |
Jobs as seamstress, dressmaker and tailor |
RF |
|
7677130 |
531 |
Alzheimer’s Disease |
human |
Jobs as seamstress, dressmaker and tailor |
RF |
|
7677130 |
532 |
Amyotrophic lateral sclerosis |
human |
Jobs as workers or farmers |
RF |
|
31155341 |
533 |
Creutzfeldt-Jakob disease |
human |
Keeping cats |
RF |
|
3066847 |
534 |
Alzheimer’s Disease |
human |
Ketones exposure |
RF |
|
7771442 |
535 |
Alzheimer's disease |
human |
lack of sports |
RF |
people with mild cognitive impairment (MCI) |
21518614 |
536 |
Amyotrophic lateral sclerosis |
human |
Leisure time activity |
RF |
|
23418211 |
537 |
Amyotrophic Lateral Sclerosis |
human |
Level of Herbicide/Pesticide Exposure |
RF |
the total SALS group |
16946624 |
537 |
Amyotrophic Lateral Sclerosis |
human |
Level of Herbicide/Pesticide Exposure |
RF |
male SALS patients |
16946624 |
538 |
Amyotrophic Lateral Sclerosis |
human |
Lifestyle factors |
RF |
Vigorous physical activity |
19342254 |
538 |
Amyotrophic Lateral Sclerosis |
human |
Lifestyle factors |
RF |
self reported stress:high |
19342254 |
538 |
Amyotrophic Lateral Sclerosis |
human |
Lifestyle factors |
RF |
Behavior pattern:Type A |
19342254 |
538 |
Amyotrophic Lateral Sclerosis |
human |
Lifestyle factors |
RF |
Intake of green-yellow vegetables:Less |
19342254 |
538 |
Amyotrophic Lateral Sclerosis |
human |
Lifestyle factors |
RF |
combination Type A behavior and Intake of green-yellow vegetables |
19342254 |
539 |
Amyotrophic lateral sclerosis |
human |
Lifetime endogenous estrogen exposure (per year) |
RF |
|
28835399 |
540 |
Alzheimer's Disease |
human |
light-moderate alcohol drinker |
RF |
|
28806610 |
541 |
Amyotrophic Lateral Sclerosis |
human |
Living in rural environment |
RF |
Region of living more than 5 years before disease onset |
31011473 |
542 |
progressive supranuclear palsy |
human |
living on a farm or ranch |
RF |
more years living on a farm or ranch |
26854325 |
543 |
Alzheimer's disease |
human |
loneliness |
RF |
people with mild cognitive impairment (MCI) |
21518614 |
544 |
Tourette Syndrome |
human |
longer delay of treatment |
RF |
|
20654033 |
545 |
Alzheimer’s Disease |
human |
low education/rural residence |
RF |
|
10636132 |
546 |
Alzheimer’s Disease |
human |
Malaria |
RF |
|
2146525 |
547 |
Motor Neuron Disease |
human |
manual occupation |
RF |
|
8229031 |
548 |
Amyotrophic Lateral Sclerosis |
human |
Market-oriented skilled agricultural workers |
RF |
|
20012543 |
549 |
Tourette Syndrome |
human |
Maternal addiction disorders |
RF |
|
28335873 |
550 |
Tourette Syndrome |
human |
Maternal affective disorders |
RF |
|
28335873 |
551 |
Tourette Syndrome |
human |
Maternal anxiety disorders |
RF |
|
28335873 |
552 |
Alzheimer's disease |
human |
Maternal breastfeeding history |
PF |
Women who breastfed had lower AD risk than women who did not breastfeed(p = 0.017) |
23948914 |
553 |
Tourette Syndrome |
human |
Maternal personality disorders |
RF |
|
28335873 |
554 |
Tourette Syndrome |
human |
maternal psychiatric diagnosis |
RF |
|
28335873 |
555 |
Tourette Syndrome |
human |
Maternal psychotic disorders |
RF |
|
28335873 |
556 |
Tourette Syndrome |
human |
Maternal toxic exposures |
RF |
Alcohol use in last 2 months of pregnancy; Mutually adjusted for other variables in the model, maternal age and socioeconomic status level. |
24262815 |
556 |
Tourette Syndrome |
human |
Maternal toxic exposures |
RF |
Cannabis use in last 2 months of pregnancy; Mutually adjusted for other variables in the model, maternal age and socioeconomic status level. |
24262815 |
557 |
Alzheimer’s Disease |
mice |
maternal transmission |
RF |
Tg2576 female mice |
29691440 |
558 |
Motor Neuron Disease |
human |
Mechanical injuries |
RF |
Site: Column |
1745327 |
558 |
Motor Neuron Disease |
human |
Mechanical injuries |
RF |
Site: Upper limbs |
1745327 |
558 |
Motor Neuron Disease |
human |
Mechanical injuries |
RF |
Site: Lower limbs |
1745327 |
558 |
Motor Neuron Disease |
human |
Mechanical injuries |
RF |
Site: Trunk |
1745327 |
558 |
Motor Neuron Disease |
human |
Mechanical injuries |
RF |
All sites |
1745327 |
559 |
Amyotrophic lateral sclerosis |
human |
medical service work |
RF |
|
27124833 |
560 |
Amyotrophic lateral sclerosis |
human |
metals as Al, Cd, Hg, Mn and Pb |
RF |
|
26671079 |
344 |
Amyotrophic lateral sclerosis |
human |
Military work |
RF |
born between 1945 and 1985 |
26468494 |
561 |
Amyotrophic lateral sclerosis |
human |
Moderate trauma |
RF |
|
29063790 |
562 |
Alzheimer’s Disease |
human |
monozygotic(MZ) twins |
RF |
twins born in Finland before 1958 with both co-twins alive in 1967 |
8596319 |
563 |
progressive supranuclear palsy |
human |
more years living within one mile of an agricultural area |
RF |
more years living within one mile of an agricultural area |
26854325 |
564 |
Parkinson's Disease |
human |
motor neuron disease (MND) |
RF |
|
20669307 |
565 |
Tuberous sclerosis complex |
human |
mutations in TSC2 |
RF |
|
26631248 |
566 |
Alzheimer's disease |
human |
Native American ancestry |
PF |
|
28369008 |
567 |
Amyotrophic lateral sclerosis |
human |
Neurological |
PF |
|
27065942 |
568 |
Alzheimer's disease |
human |
no chronic use of nonsteroidal anti-inflammatory drugs |
PF |
|
18446027 |
569 |
Amyotrophic lateral sclerosis |
human |
Non Vigorous Physical Activities |
RF |
|
28413696 |
570 |
Parkinson's Disease |
human |
non‐apnea sleep disorders (NSD) |
RF |
|
28470725 |
571 |
Parkinson's Disease |
human |
non-hydroxychloroquine immunosuppressant therapy |
PF |
Sj?gren syndrome (SS) |
30946325 |
572 |
Alzheimer's Disease |
human |
Nonmarried |
RF |
|
25401488 |
573 |
Alzheimer's disease |
human |
nonstroke cardiovascular disease (CVD) |
RF |
in carriers of the ApoE4 allele |
20473139 |
574 |
Alzheimer's disease |
human |
normal tension glaucoma (NTG) |
RF |
Among patients with NTG, none of the glaucoma eye drops used significantly changed the risk of subsequent AD. |
30397009 |
575 |
Motor Neuron Disease |
human |
number of children |
RF |
number of children:3 |
1745327 |
576 |
Creutzfeldt-Jakob disease |
human |
Number of surgical procedures |
RF |
1 time |
12196646 |
576 |
Creutzfeldt-Jakob disease |
human |
Number of surgical procedures |
RF |
2 times |
12196646 |
576 |
Creutzfeldt-Jakob disease |
human |
Number of surgical procedures |
RF |
>=3 times |
12196646 |
577 |
Amyotrophic lateral sclerosis |
human |
O2?tension |
RF |
low O2?tension |
30863976 |
315 |
Alzheimer’s Disease |
human |
Obesity |
RF |
|
29606955 |
315 |
Alzheimer's Disease |
human |
Obesity |
RF |
|
26495049 |
315 |
Alzheimer's Disease |
human |
Obesity |
RF |
|
26324099 |
315 |
Alzheimer's disease |
|
Obesity |
RF |
|
31191220 |
315 |
Alzheimer's disease |
human |
obesity |
RF |
|
30792733 |
315 |
Amyotrophic lateral sclerosis |
human |
Obesity |
PF |
Unadjusted |
26030836 |
315 |
Amyotrophic lateral sclerosis |
human |
Obesity |
RF |
|
27065942 |
315 |
Frontotemporal Dementia |
human |
obesity |
RF |
|
30792733 |
315 |
Frontotemporal Lobar Degeneration |
human |
Obesity |
RF |
|
30792733 |
315 |
Motor Neuron Disease |
human |
Obesity |
PF |
BMI>=30 |
22559076 |
578 |
Motor Neuron Disease |
human |
Occupation |
RF |
Work as farmers and breeders |
1745327 |
578 |
Amyotrophic Lateral Sclerosis |
human |
Occupation |
RF |
Craft and related trades workers(Crude OR) |
17923612 |
578 |
Amyotrophic Lateral Sclerosis |
human |
Occupation |
RF |
primary industrial occupations(at disease onset) |
17538776 |
578 |
Amyotrophic Lateral Sclerosis |
human |
Occupation |
RF |
secondary industrial occupations(at disease onset) |
17538776 |
578 |
Amyotrophic Lateral Sclerosis |
human |
Occupation |
PF |
tertiary industrial occupations(at disease onset) |
17538776 |
578 |
Amyotrophic lateral sclerosis |
human |
Occupation |
RF |
Occupations in contact with customer;sworked or were unemployed at 1991 Italian census, and were still resident in Turin at the beginning of 1996 |
28201634 |
578 |
Amyotrophic lateral sclerosis |
human |
Occupation |
RF |
Primary occupation involves industrial chemicals;residents of New England or the bordering New York region at the time of enrollment |
28122372 |
578 |
Amyotrophic lateral sclerosis |
human |
Occupation |
RF |
Primary occupation involves industrial chemicals;residents of New England or the bordering New York region at the time of enrollment |
28122372 |
579 |
Creutzfeldt-Jakob disease |
human |
Occupational Exposure |
RF |
occupational exposure to animal laboratory |
19144172 |
579 |
Motor Neuron Disease |
human |
Occupational Exposure |
RF |
occupational exposure to lead |
8229031 |
579 |
Motor Neuron Disease |
human |
Occupational Exposure |
RF |
occupational exposure to solvents/chemicals |
8229031 |
579 |
Amyotrophic lateral sclerosis |
human |
Occupational Exposure |
PF |
Occupational exposure to lead;Exposure Ever Happened in Entire Occupational History |
27159543 |
579 |
Amyotrophic lateral sclerosis |
human |
Occupational Exposure |
RF |
Occupational exposure to pesticide;Exposure in the last 30 years |
24979055 |
579 |
Amyotrophic lateral sclerosis |
human |
Occupational Exposure |
RF |
Occupational exposure to pesticide;Exposure Ever Happened in Entire Occupational History |
27159543 |
579 |
Amyotrophic lateral sclerosis |
human |
Occupational Exposure |
RF |
Occupational exposure to pesticide;Exposure Ever Happened in Last 10 years |
27159543 |
579 |
Amyotrophic lateral sclerosis |
human |
Occupational Exposure |
RF |
Occupational exposure to pesticide;Exposure Ever Happened 10-30 years Ago |
27159543 |
579 |
progressive supranuclear palsy |
human |
Occupational Exposure |
RF |
occupational metal exposure |
26854325 |
580 |
Amyotrophic Lateral Sclerosis |
human |
Occupational history |
RF |
Occupational history:Building and construction sector of economic activity;Spinal cases |
19922125 |
580 |
Amyotrophic Lateral Sclerosis |
human |
Occupational history |
RF |
Occupational history:Exposure to building and construction materials;Spinal cases |
19922125 |
580 |
Amyotrophic Lateral Sclerosis |
human |
Occupational history |
RF |
Occupational history:Exposure to metals and metal fumes;Spinal cases |
19922125 |
581 |
Amyotrophic lateral sclerosis |
human |
OCP(oral contraceptive) |
PF |
female |
28835399 |
582 |
Amyotrophic lateral sclerosis |
human |
office work |
RF |
|
27124833 |
583 |
Alzheimer's disease |
human |
often taking part in recreational activities |
PF |
people with mild cognitive impairment (MCI) |
21518614 |
584 |
Alzheimer's Disease |
human |
okra |
RF |
particularly in people carrying a H63D polymorphism |
26170247 |
585 |
Amyotrophic lateral sclerosis |
human |
Organic solvents |
RF |
|
29681882 |
586 |
Amyotrophic lateral sclerosis |
human |
Organized sport activity |
PF |
|
24706338 |
586 |
Amyotrophic lateral sclerosis |
human |
Organized sport activity |
PF |
Significant adjusted OR |
24706338 |
587 |
Parkinson's Disease |
human |
organophosphate (OP) or carbamate (CM) poisoning |
RF |
|
27781262 |
588 |
Alzheimer’s Disease |
human |
Other solvents exposure |
RF |
|
7771442 |
589 |
Amyotrophic lateral sclerosis |
human |
overall muscle strength |
RF |
Low overall muscle strength |
29285652 |
590 |
Amyotrophic Lateral Sclerosis |
human |
pack-years |
RF |
Bulbar cases |
19922125 |
591 |
Parkinson's Disease |
human |
paraquat exposure |
RF |
|
23150532 |
592 |
Alzheimer's disease |
human |
Parental death during childhood |
RF |
with strength of these associations attenuated by remarriage of the widowed parent. |
21873837 |
593 |
Amyotrophic lateral sclerosis |
human |
particulate matter |
RF |
PM2.5, PM10, and PMcoarse |
29483062 |
594 |
Amyotrophic lateral sclerosis |
human |
particulate matter absorption |
RF |
PM2.5absorption |
29483062 |
595 |
Tourette Syndrome |
human |
Paternal anxiety disorders |
RF |
|
28335873 |
596 |
Tourette Syndrome |
human |
Paternal OCD |
RF |
|
28335873 |
597 |
Tourette Syndrome |
human |
paternal psychiatric diagnosis |
RF |
|
28335873 |
598 |
Parkinson's Disease |
rat |
Peripheral inflammation |
RF |
|
20584104 |
599 |
Alzheimer’s Disease |
human |
Peripheral vascular disease |
PF |
after Hemodialysis Initiation |
30093374 |
600 |
Alzheimer's Disease |
human |
personal experience with AD |
RF |
|
28605999 |
601 |
Creutzfeldt-Jakob disease |
human |
Pets |
RF |
other than cats/dogs |
3066847 |
602 |
Alzheimer’s Disease |
human |
Phenols, alcohols exposure |
RF |
|
7771442 |
603 |
Alzheimer's disease |
human |
phosphatidylinositol clathrin assembly lymphoid-myeloid leukemia (PICALM) |
RF |
|
24067654 |
604 |
Amyotrophic lateral sclerosis |
human |
Physical activity |
PF |
|
24706338 |
604 |
Amyotrophic lateral sclerosis |
human |
Physical activity |
PF |
Significant adjusted OR |
24706338 |
605 |
Alzheimer’s Disease |
human |
Physical inactivity |
RF |
|
29606955 |
605 |
Alzheimer's Disease |
human |
Physical Inactivity |
RF |
|
26495049 |
606 |
Alzheimer’s Disease |
human |
Physically underactive |
RF |
|
2146525 |
606 |
Alzheimer’s Disease |
human |
Physically underactive |
RF |
|
2146525 |
607 |
Multiple System Atrophy |
human |
plant and machine operators and assemblers |
RF |
|
18307243 |
607 |
Multiple System Atrophy |
human |
plant and machine operators and assemblers |
RF |
≤ 11 years |
18307243 |
607 |
Multiple System Atrophy |
human |
plant and machine operators and assemblers |
RF |
≥ 11years |
18307243 |
608 |
Parkinson's Disease |
human |
Plant Extract |
PF |
|
24955210 |
609 |
Amyotrophic Lateral Sclerosis |
human |
playing professional football |
RF |
>5 years |
15634730 |
610 |
Parkinson's Disease |
human |
Polychlorinated biphenyls (PCBs)exposure |
RF |
greater susceptibility of females. |
22906799 |
610 |
Parkinson's Disease |
human |
Polychlorinated biphenyls (PCBs)exposure |
RF |
greater susceptibility of females. |
22906799 |
611 |
Tuberous sclerosis complex |
human |
poor control of subsequent seizures after IS |
RF |
|
16043792 |
612 |
Amyotrophic Lateral Sclerosis |
human |
precision metal workers |
RF |
|
19750102 |
613 |
Alzheimer’s Disease |
human |
pregnancy |
RF |
pregnant 5xFAD transgenic mice |
29855361 |
614 |
Tourette Syndrome |
human |
Pregnancy complications |
RF |
Less than adequate weight gain; Mutually adjusted for other variables in the model, maternal age and socioeconomic status level. |
24262815 |
615 |
Alzheimer's Disease |
human |
prenatal estrogen exposure |
RF |
lower levels of prenatal estrogen exposure |
24968011 |
616 |
Tourette Syndrome |
human |
pre-natal maternal depression |
RF |
mothers' pre-natal maternal depression affecting the offspring |
26174227 |
617 |
Tourette Syndrome |
human |
Prenatal maternal smoking |
RF |
Prenatal maternal smoking affecting the offspring |
25796373 |
618 |
Alzheimer's Disease |
human |
prenatal testosterone exposure |
RF |
lower levels of prenatal testosterone exposure |
24968011 |
619 |
Parkinson's Disease |
human |
pretreatment motor dysfunction |
RF |
especially among older patients |
9447497 |
620 |
Parkinson's Disease |
human |
Prior stroke |
RF |
|
31019987 |
621 |
Alzheimer’s Disease |
human |
Probable solvent exposure |
RF |
Any above-named solvent or "job description." |
7771442 |
621 |
Alzheimer’s Disease |
human |
Probable solvent exposure |
RF |
Any above-named solvent or "job description." |
7771442 |
622 |
Amyotrophic lateral sclerosis |
human |
Professional sports |
RF |
|
29681882 |
623 |
Tuberous sclerosis complex |
human |
prolonged duration of IS |
RF |
per 1-month interval |
16043792 |
624 |
Tuberous sclerosis complex |
human |
prolonged time from treatment initiation until the cessation of IS |
RF |
|
16043792 |
625 |
Alzheimer's disease |
human |
Proton pump inhibitors (PPIs) |
RF |
Chronic consumption of PPIs |
20456731 |
626 |
Parkinson's Disease |
human |
psychiatric disorder |
RF |
particularly in people under age 50 |
18080857 |
627 |
Creutzfeldt-Jakob disease |
human |
Psychiatric visit |
RF |
|
12196646 |
628 |
Alzheimer’s Disease |
human |
Race |
RF |
after Hemodialysis Initiation |
30093374 |
628 |
Alzheimer’s Disease |
human |
Race |
RF |
after Hemodialysis Initiation |
30093374 |
628 |
Amyotrophic lateral sclerosis |
human |
Race |
RF |
AA |
27065942 |
628 |
Amyotrophic lateral sclerosis |
human |
Race |
PF |
other |
27065942 |
629 |
Amyotrophic lateral sclerosis |
human |
Reading |
PF |
|
31155341 |
629 |
Alzheimer's Disease |
human |
Reading |
RF |
reading occasionally |
28806610 |
629 |
Alzheimer's disease |
human |
Reading |
PF |
people with mild cognitive impairment (MCI) |
21518614 |
630 |
Alzheimer's disease |
human |
regular "mind-body" religious meditative activities(or kowtow) |
PF |
|
26757186 |
631 |
Creutzfeldt-Jakob disease |
human |
regular GP visits |
RF |
|
19144172 |
632 |
Creutzfeldt-Jakob disease |
human |
regular medication |
RF |
|
19144172 |
633 |
Chronic Traumatic Encephalopathy |
mice |
Repeated mild traumatic brain injury (r-mTBI) |
RF |
APOE3 and APOE4 specific effects following injury in a mouse model of r-mTBI |
30711612 |
634 |
Creutzfeldt-Jakob disease |
human |
Residence or employment |
RF |
Live or employed in farms |
10073510 |
635 |
Amyotrophic lateral sclerosis |
human |
Retirement or unemployment |
PF |
|
31155341 |
636 |
Parkinson's Disease |
human |
Rosacea constitutes |
RF |
|
26999031 |
637 |
Parkinson's Disease |
human |
Rural living |
RF |
|
21059511 |
637 |
Parkinson's Disease |
human |
Rural living |
RF |
|
11437458 |
637 |
Parkinson's Disease |
human |
Rural living |
RF |
|
11437458 |
637 |
Parkinson's Disease |
human |
Rural living |
RF |
|
9778597 |
638 |
Alzheimer's Disease |
human |
Rural residency |
RF |
|
25401488 |
639 |
Amyotrophic lateral sclerosis |
human |
SAH(subarachnoid haemorrhage) |
RF |
Transient ischaemic attack |
26260352 |
640 |
Amyotrophic lateral sclerosis |
human |
Sales representatives |
RF |
worked or were unemployed at 1991 Italian census, and were still resident in Turin at the beginning of 1996 |
28201634 |
641 |
Tourette Syndrome |
human |
second-degree relatives |
RF |
|
26083307 |
642 |
Tuberous sclerosis complex |
human |
Seizure type (ie, infantile spasms) |
RF |
|
9520012 |
643 |
Amyotrophic Lateral Sclerosis |
human |
selenium overexposure |
RF |
|
21215776 |
644 |
Alzheimer's Disease |
human |
serum cholesterol |
RF |
|
22904031 |
645 |
Tuberous sclerosis complex |
human |
severe mental retardation |
RF |
|
28721058 |
646 |
Alzheimer's Disease |
human |
severe OSA(obstructive sleep apnea) |
RF |
≥30 vs. <5 apnea-hypopnea events/hour;using adjudicated outcomes |
28738188 |
647 |
Amyotrophic lateral sclerosis |
human |
Severe physical activities |
PF |
|
31155341 |
648 |
Alzheimer's Disease |
human |
severe PWMH |
RF |
in male |
26343475 |
649 |
Parkinson's Disease |
human |
Sj?gren syndrome (SS) |
RF |
|
30946325 |
650 |
Alzheimer's Disease |
human |
Sleep disturbance |
RF |
Model 1: Main effect unadjusted |
29077487 |
650 |
Alzheimer's Disease |
human |
Sleep disturbance |
RF |
Model 2: Main effects adjusted for sex, education, age, and race. |
29077487 |
650 |
Alzheimer's Disease |
human |
Sleep disturbance |
RF |
Model 3: Main effects adjusted for adjusted for sex, age, education, race, e4 carrier status |
29077487 |
650 |
Alzheimer's Disease |
human |
Sleep disturbance |
RF |
Model 4: Main effects adjusted for adjusted for sex, age, education, race, e4 carrier status, the presence of hypertension and hypercholesterolemia |
29077487 |
651 |
Alzheimer's disease |
|
Sleep-wake regulation |
RF |
|
30649520 |
652 |
Alzheimer's disease |
human |
Smoking |
RF |
Current smokers |
21187587 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
current smokers |
22791740 |
652 |
Alzheimer's Disease |
human |
Smoking |
RF |
current smoking |
28806610 |
652 |
Alzheimer's Disease |
human |
Smoking |
RF |
in Mongolian males aged over 55 years |
25657695 |
652 |
Multiple System Atrophy |
human |
Smoking |
RF |
≥40 pack-years |
20623770 |
652 |
Multiple System Atrophy |
human |
Smoking |
RF |
≥40 pack-years |
20623770 |
652 |
Tourette Syndrome |
human |
Smoking |
RF |
maternal smoking |
22738448 |
652 |
Tourette Syndrome |
human |
Smoking |
RF |
maternal smoking |
20654033 |
652 |
Alzheimer's Disease |
human |
Smoking |
RF |
|
23422663 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Ever smoker(Adjustment for education) |
10645818 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Current smoker(Adjustment for education) |
10645818 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Ever smoker(Adjustment for education and alcohol consumption) |
10645818 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Current smoker(Adjustment for education and alcohol consumption) |
10645818 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Duration of smoking ≥20 years(Adjustment for education) |
10645818 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Duration of smoking ≥20 years(Adjustment for education and alcohol consumption) |
10645818 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Cumulative pack-years<20 pack-years(Adjustment for education) |
10645818 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Cumulative pack-years≥20 pack-years(Adjustment for education) |
10645818 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Cumulative pack-years<20 pack-years(Adjustment for education and alcohol consumption) |
10645818 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Cumulative pack-years≥20 pack-years(Adjustment for education and alcohol consumption) |
10645818 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Combination recency and dose:Current, <20 pack years(Adjustment for education) |
10645818 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Combination recency and
dose:Current, ≥20 pack-years(Adjustment for education and alcohol consumption) |
10645818 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Combination recency and
dose:Current, <20 pack years(Adjustment for education) |
10645818 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Combination recency and
dose:Current, ≥20 pack-years(Adjustment for education and alcohol consumption) |
10645818 |
652 |
Alzheimer’s Disease |
human |
Smoking |
PF |
|
30103328 |
652 |
Alzheimer’s Disease |
human |
Smoking |
RF |
|
29606955 |
652 |
Alzheimer’s Disease |
human |
Smoking |
RF |
|
2754163 |
652 |
Alzheimer’s Disease |
human |
Smoking |
PF |
Light smoker |
9346343 |
652 |
Alzheimer’s Disease |
human |
Smoking |
RF |
Daily smoker |
9346343 |
652 |
Alzheimer's Disease |
human |
Smoking |
RF |
|
26495049 |
652 |
Alzheimer's Disease |
human |
Smoking |
RF |
|
24596166 |
652 |
Alzheimer's disease |
human |
Smoking |
PF |
|
30792733 |
652 |
Alzheimer's disease |
human |
Smoking |
RF |
smoking more than 2 packs a day |
20975015 |
652 |
Alzheimer's disease |
human |
Smoking |
RF |
in APOE e4 carriers |
20847559 |
652 |
Amyotrophic lateral sclerosis |
human |
Smoking |
RF |
|
31155341 |
652 |
Amyotrophic lateral sclerosis |
human |
Smoking |
RF |
|
30786056 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Former smokers (Adjusted for Age) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Current smokers (Adjusted for Age) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Ever smokers (Adjusted for Age) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Pack-years smoked ≤20 (Adjusted for Age) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Pack-years smoked 21-35 (Adjusted for Age) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Pack-years smoked > 35 (Adjusted for Age) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Former smokers (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Ever smokers (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Pack-years smoked ≤20 (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Pack-years smoked 21-35 (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Pack-years smoked > 35 (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Former smokers (Adjusted for Age) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Ever smokers (Adjusted for Age) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Pack-years smoked 21-35 (Adjusted for Age) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Former smokers (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Ever smokers (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Pack-years smoked 21-35 (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Former smokers (Adjusted for Age) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Ever smokers (Adjusted for Age) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Pack-years smoked ≤20 (Adjusted for Age) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Pack-years smoked >35(Adjusted for Age) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Former smokers (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Ever smokers (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Pack-years smoked ≤20 (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Pack-years smoked >35(Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Current(Crude OR) |
17923612 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Current(Adj. OR) |
17923612 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Current smokers |
19399866 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Time spent smoking≥30years |
19399866 |
652 |
Motor Neuron Disease |
human |
Smoking |
RF |
Ever smokers |
22559076 |
652 |
Parkinson's Disease |
human |
Smoking |
PF |
|
21059511 |
652 |
Parkinson's Disease |
human |
Smoking |
PF |
|
19540050 |
652 |
Parkinson's Disease |
human |
Smoking |
PF |
|
11060508 |
652 |
Parkinson's Disease |
human |
Smoking |
PF |
|
19188574 |
652 |
Parkinson's Disease |
human |
Smoking |
PF |
|
30772279 |
652 |
Alzheimer’s Disease |
human |
Smoking |
RF |
intrinsic epigenetic age acceleration; current smoker (N=939); former smoker, stopped within past 12 months (N=158); former smoker, stopped more than 12 months ago (N=1309); never smoker (N=2533), and not coded (N=62). |
30167451 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Bulbar cases |
19922125 |
652 |
Amyotrophic Lateral Sclerosis |
human |
Smoking |
RF |
Bulbar cases |
19922125 |
653 |
Parkinson's Disease |
human |
SN hyperechogenicity (SN+) |
RF |
|
23115051 |
654 |
Tourette Syndrome |
human |
socio-economic status (SES) |
RF |
Low socio-economic status (SES) |
24138188 |
655 |
Alzheimer’s Disease |
human |
Socioeconomic status (SIMD, SD) |
RF |
intrinsic epigenetic age acceleration |
30167451 |
656 |
Alzheimer’s Disease |
human |
Solvent exposure |
RF |
Any positive response to a named solvent group |
7771442 |
656 |
Alzheimer’s Disease |
human |
Solvent exposure |
RF |
Any positive response to a named solvent group. |
7771442 |
657 |
Amyotrophic Lateral Sclerosis |
human |
Solvents/Chemicals |
RF |
with the total SALS group |
16946624 |
657 |
Amyotrophic Lateral Sclerosis |
human |
Solvents/Chemicals |
RF |
with male patients |
16946624 |
657 |
Amyotrophic Lateral Sclerosis |
human |
Solvents/Chemicals |
RF |
with female patients |
16946624 |
658 |
Alzheimer's disease |
human |
soy food products |
RF |
|
24440006 |
659 |
Amyotrophic Lateral Sclerosis |
human |
spatial locations |
RF |
|
18573277 |
660 |
Amyotrophic lateral sclerosis |
human |
Sport activity |
PF |
|
24706338 |
661 |
Alzheimer's disease |
human |
statin use |
PF |
|
20533968 |
662 |
Alzheimer's Disease |
human |
stress |
RF |
chronic stress |
20044001 |
663 |
Alzheimer's disease |
human |
stroke |
RF |
previous stroke history |
24489845 |
663 |
Alzheimer's disease |
human |
stroke |
RF |
mediated the association between selected CV risk factors and LOAD |
27533593 |
663 |
Alzheimer's disease |
human |
stroke |
RF |
mediated the association between selected CV risk factors and LOAD |
27533593 |
663 |
Amyotrophic lateral sclerosis |
human |
Stroke |
RF |
all |
26260352 |
663 |
Amyotrophic lateral sclerosis |
human |
Stroke |
RF |
Haemorrhagic |
26260352 |
663 |
Amyotrophic lateral sclerosis |
human |
Stroke |
RF |
Ischaemic |
26260352 |
663 |
Amyotrophic lateral sclerosis |
human |
Stroke |
RF |
Unspecified |
26260352 |
663 |
Parkinson's Disease |
human |
stroke |
RF |
|
26576320 |
663 |
Parkinson's Disease |
human |
stroke |
RF |
|
9778597 |
664 |
Alzheimer’s Disease |
human |
Stroke/transient ischemic attack |
RF |
after Hemodialysis Initiation |
30093374 |
665 |
Creutzfeldt-Jakob disease |
human |
Surgery |
RF |
undergo surgery |
18257690 |
665 |
Creutzfeldt-Jakob disease |
human |
Surgery |
PF |
undergo surgery |
18257690 |
665 |
Creutzfeldt-Jakob disease |
human |
Surgery |
PF |
undergo surgery;used proxy informants to acquire information about case subjects and control subjects (consistent ascertainment) |
18257690 |
665 |
Creutzfeldt-Jakob disease |
human |
Surgery |
RF |
undergo surgery;proxy informants acted only on behalf of case subjects (inconsistent data ascertainment) |
18257690 |
665 |
Creutzfeldt-Jakob disease |
human |
Surgery |
RF |
|
10073510 |
665 |
Creutzfeldt-Jakob disease |
human |
Surgery |
PF |
Surgery at any time |
3066847 |
665 |
Creutzfeldt-Jakob disease |
human |
Surgery |
RF |
Any surgery |
12196646 |
665 |
Creutzfeldt-Jakob disease |
human |
Surgery |
PF |
Tonsillectomy |
12196646 |
665 |
Creutzfeldt-Jakob disease |
human |
Surgery |
PF |
Appendectomy |
12196646 |
665 |
Creutzfeldt-Jakob disease |
human |
Surgery |
RF |
Gynecologic |
12196646 |
665 |
Creutzfeldt-Jakob disease |
human |
Surgery |
RF |
|
18843192 |
665 |
Creutzfeldt-Jakob disease |
human |
Surgery |
RF |
predating clinical onset by 1 or more years |
18843192 |
665 |
Creutzfeldt-Jakob disease |
human |
Surgery |
RF |
at a 1- to 9-year time lag |
18843192 |
665 |
Creutzfeldt-Jakob disease |
human |
Surgery |
RF |
ophthalmological surgery (> 1980) |
19144172 |
665 |
Creutzfeldt-Jakob disease |
human |
Surgery |
RF |
orthopaedic surgery |
19144172 |
665 |
Creutzfeldt-Jakob disease |
human |
Surgery |
RF |
orthopaedic surgery (> 1980) |
19144172 |
666 |
Parkinson's Disease |
human |
tea drinking |
RF |
|
11060508 |
667 |
Tuberous sclerosis complex |
human |
The presence of seizures |
RF |
|
21449900 |
668 |
Amyotrophic lateral sclerosis |
human |
The widespread distribution of dioxins, PCBs and PAHs |
RF |
|
28476168 |
669 |
Tourette Syndrome |
human |
third-degree relatives |
RF |
|
26083307 |
670 |
Amyotrophic lateral sclerosis |
human |
Thyroid |
PF |
|
27065942 |
671 |
Amyotrophic lateral sclerosis |
human |
toenail mercury levels |
RF |
|
29314106 |
672 |
Parkinson's Disease |
human |
Total daily physical activity |
PF |
Older adults |
31046115 |
673 |
Alzheimer’s Disease |
human |
Total:HDL cholesterol (ratio) |
RF |
extrinsic epigenetic age acceleration |
30167451 |
674 |
Amyotrophic Lateral Sclerosis |
human |
Toxin exposure |
RF |
|
16963407 |
675 |
Parkinson's Disease |
human |
Toxins other than pesticide |
RF |
|
21059511 |
676 |
Amyotrophic lateral sclerosis |
human |
Trauma |
RF |
Previous trauma |
29681882 |
676 |
Amyotrophic lateral sclerosis |
human |
Trauma |
RF |
|
25059395 |
676 |
Amyotrophic Lateral Sclerosis |
human |
Trauma |
RF |
At least one traumatic event(All traumatic event) |
22537412 |
676 |
Amyotrophic Lateral Sclerosis |
human |
Trauma |
RF |
Number of events reported:1(All traumatic event) |
22537412 |
676 |
Amyotrophic Lateral Sclerosis |
human |
Trauma |
RF |
Number of events reported:3+(All traumatic event) |
22537412 |
676 |
Amyotrophic Lateral Sclerosis |
human |
Trauma |
RF |
Worst traumatic event reported:Moderate(All traumatic event) |
22537412 |
676 |
Amyotrophic Lateral Sclerosis |
human |
Trauma |
RF |
Worst traumatic event reported:Severe(All traumatic event) |
22537412 |
676 |
Amyotrophic Lateral Sclerosis |
human |
Trauma |
RF |
Number of events requiring hospitalization:1(All traumatic event) |
22537412 |
676 |
Amyotrophic Lateral Sclerosis |
human |
Trauma |
RF |
Number of events leading to disability:1(All traumatic event) |
22537412 |
676 |
Amyotrophic Lateral Sclerosis |
human |
Trauma |
RF |
At least one traumatic event(Old traumatic events) |
22537412 |
676 |
Amyotrophic Lateral Sclerosis |
human |
Trauma |
RF |
Number of events reported:2(Old traumatic events) |
22537412 |
676 |
Amyotrophic Lateral Sclerosis |
human |
Trauma |
RF |
Number of events reported::3+(Old traumatic events) |
22537412 |
676 |
Amyotrophic Lateral Sclerosis |
human |
Trauma |
RF |
Worst traumatic event reported:Moderate(Old traumatic events) |
22537412 |
676 |
Amyotrophic Lateral Sclerosis |
human |
Trauma |
RF |
Worst traumatic event reported:Severe(Old traumatic events) |
22537412 |
676 |
Amyotrophic Lateral Sclerosis |
human |
Trauma |
RF |
Number of events requiring hospitalization:2+(Old traumatic events) |
22537412 |
676 |
Amyotrophic Lateral Sclerosis |
human |
Trauma |
RF |
Number of events leading to disability:2+(Old traumatic events) |
22537412 |
677 |
Amyotrophic lateral sclerosis |
human |
Trauma leading to disability |
RF |
|
29063790 |
677 |
Amyotrophic lateral sclerosis |
human |
Trauma leading to disability |
RF |
|
29063790 |
677 |
Amyotrophic lateral sclerosis |
human |
Trauma leading to disability |
RF |
1 Trauma |
29063790 |
677 |
Amyotrophic lateral sclerosis |
human |
Trauma leading to disability |
RF |
1 Trauma |
29063790 |
677 |
Amyotrophic lateral sclerosis |
human |
Trauma leading to disability |
RF |
2+ Trauma |
29063790 |
677 |
Amyotrophic lateral sclerosis |
human |
Trauma leading to disability |
RF |
2+ Trauma |
29063790 |
678 |
Frontotemporal Dementia |
human |
traumatic brain injury (TBI) |
RF |
|
28946566 |
678 |
Frontotemporal Dementia |
human |
traumatic brain injury (TBI) |
RF |
|
25982564 |
678 |
Alzheimer's Disease |
human |
Traumatic brain injury (TBI) |
RF |
|
26401777 |
678 |
Frontotemporal Dementia |
human |
traumatic brain injury (TBI) |
RF |
|
22465176 |
678 |
Frontotemporal Lobar Degeneration |
human |
traumatic brain injury (TBI) |
RF |
|
22465176 |
678 |
Frontotemporal Lobar Degeneration |
human |
traumatic brain injury (TBI) |
RF |
Remote TBI with extended loss of consciousness (TBI-ext) |
25531628 |
678 |
Chronic Traumatic Encephalopathy |
mice |
Traumatic brain injury (TBI) |
RF |
through the induction of tau hyperphosphorylation and aggregation |
31317824 |
678 |
Parkinson's Disease |
human |
Traumatic brain injury (TBI) |
RF |
|
23150532 |
679 |
Alzheimer's Disease |
human |
traumatic brain injury (TBI) with reported loss of consciousness (LOC) |
RF |
|
29389151 |
680 |
Alzheimer's Disease |
human |
treadmill exercise |
PF |
|
25960981 |
681 |
Parkinson's Disease |
human |
Trichloroethylene |
RF |
|
18157908 |
682 |
Parkinson's Disease |
human |
type 1 Gaucher disease |
RF |
|
20177787 |
683 |
Parkinson's Disease |
human |
Type 2 diabetes |
RF |
|
17251276 |
683 |
Parkinson's Disease |
human |
Type 2 diabetes |
RF |
|
17251276 |
684 |
Alzheimer's disease |
human |
type 2 diabetes mellitus (T2DM) |
RF |
a risk factor for MCI progressing into AD |
27729793 |
685 |
Amyotrophic Lateral Sclerosis |
human |
Type of Herbicide/Pesticide Exposure |
RF |
Industrial exposure to herbicides/pesticides |
16946624 |
685 |
Amyotrophic Lateral Sclerosis |
human |
Type of Herbicide/Pesticide Exposure |
RF |
Industrial exposure to herbicides/pesticides |
16946624 |
685 |
Amyotrophic Lateral Sclerosis |
human |
Type of Herbicide/Pesticide Exposure |
RF |
industrial exposure being occasional |
16946624 |
685 |
Amyotrophic Lateral Sclerosis |
human |
Type of Herbicide/Pesticide Exposure |
RF |
industrial exposure being occasional |
16946624 |
685 |
Amyotrophic Lateral Sclerosis |
human |
Type of Herbicide/Pesticide Exposure |
RF |
industrial exposure being regular |
16946624 |
685 |
Amyotrophic Lateral Sclerosis |
human |
Type of Herbicide/Pesticide Exposure |
RF |
industrial exposure being regular |
16946624 |
685 |
Amyotrophic Lateral Sclerosis |
human |
Type of Herbicide/Pesticide Exposure |
RF |
Exposure to herbicides/pesticides through regular gardening |
16946624 |
685 |
Amyotrophic Lateral Sclerosis |
human |
Type of Herbicide/Pesticide Exposure |
RF |
Exposure to herbicides/pesticides through regular gardening |
16946624 |
686 |
Tourette Syndrome |
human |
type of home education |
RF |
|
22738448 |
687 |
Alzheimer's Disease |
human |
underweight |
RF |
at age 30, 40, or 45 years |
18835864 |
688 |
Alzheimer's disease |
human |
urbanization status |
RF |
|
24489845 |
689 |
Parkinson's Disease |
human |
Uric Acid |
PF |
|
24955210 |
690 |
Amyotrophic lateral sclerosis |
human |
Use of chemicals in job or hobby |
RF |
residents of New England or the bordering New York region at the time of enrollment |
28122372 |
690 |
Amyotrophic lateral sclerosis |
human |
Use of chemicals in job or hobby |
RF |
residents of New England or the bordering New York region at the time of enrollment |
28122372 |
691 |
progressive supranuclear palsy |
human |
Use of firearm in service |
RF |
|
29973911 |
692 |
Amyotrophic lateral sclerosis |
human |
Use of statins |
PF |
|
25059395 |
693 |
Amyotrophic lateral sclerosis |
human |
Using fertilizer to treat gardens |
RF |
Exposure in the period from 30 years ago to 10 years ago |
24979055 |
694 |
Alzheimer's Disease |
human |
vascular risk |
RF |
|
20164563 |
695 |
Alzheimer's disease |
human |
vascular risk factors(hypertension, diabetes, cerebrovascular diseases, and hypercholesterolemia) |
RF |
people with mild cognitive impairment (MCI) |
21490316 |
696 |
Parkinson's Disease |
human |
Vitamin D and Vitamin E |
PF |
|
24955210 |
697 |
Alzheimer's disease |
human |
vitamin D insufficiency |
RF |
|
22306846 |
698 |
Alzheimer's disease |
mice |
Vulnerability to stress |
RF |
pharmacological treatment with venlafaxine may represent a therapeutic strategy for the treatment of stress-related disorders, including AD |
21797840 |
699 |
Alzheimer’s Disease |
human |
Wandering |
RF |
exhibit wandering in the middle or late stages |
8422268 |
700 |
Amyotrophic lateral sclerosis |
human |
Water-Ski |
RF |
residents of New England or the bordering New York region at the time of enrollment |
28122372 |
701 |
Alzheimer's Disease |
human |
weight gain |
RF |
between 30 and 50 years for any 5-year interval |
18835864 |
702 |
Parkinson's Disease |
human |
welding |
RF |
|
11148228 |
451 |
Parkinson's Disease |
human |
well water ingestion |
RF |
|
18464276 |
451 |
Parkinson's Disease |
human |
well water ingestion |
RF |
|
12140099 |
451 |
Parkinson's Disease |
human |
well water ingestion |
RF |
|
11437458 |
451 |
Parkinson's Disease |
human |
well water ingestion |
RF |
|
9778597 |
703 |
Amyotrophic lateral sclerosis |
human |
Work |
PF |
|
24706338 |
703 |
Amyotrophic lateral sclerosis |
human |
Work |
PF |
Significant adjusted OR |
24706338 |
704 |
Amyotrophic lateral sclerosis |
human |
Work & Sport |
PF |
|
24706338 |
704 |
Amyotrophic lateral sclerosis |
human |
Work & Sport |
PF |
Significant adjusted OR |
24706338 |
705 |
Alzheimer’s Disease |
human |
Years of education |
PF |
|
30103328 |
706 |
Alzheimer’s Disease |
human |
Yemenite origin |
RF |
|
30103328 |
707 |
Creutzfeldt-Jakob disease |
human |
Zoster |
RF |
Zoster in adult life |
3066847 |
708 |
Alzheimer's Disease |
human |
β- hexachlorocyclohexane |
RF |
|
22904031 |
526 |
Alzheimer’s Disease |
human |
Insulin resistance (IR) |
RF |
|
30112972 |
422 |
Alzheimer's disease |
human |
Dyslipidemia |
RF |
|
31771063 |
422 |
Alzheimer's disease |
human |
Dyslipidemia |
RF |
(a higher LDL cholesterol level) |
32903761 |
931 |
Alzheimer's disease |
human |
Multiple vascular risk factors (VRFs) |
RF |
especially in APOE ε4 carriers |
31587263 |
932 |
Alzheimer's disease |
human |
Depressive symptoms |
RF |
for pre-frailty and frailty in patients with AD |
32335425 |
400 |
Alzheimer's disease |
human |
depression |
RF |
|
33126696 |
933 |
Alzheimer's disease |
human |
diabetes mellitus |
RF |
|
33126696 |
934 |
Alzheimer's disease |
human |
older age |
RF |
|
33126696 |
935 |
Alzheimer's disease |
human |
treated dyslipidemia |
PF |
|
33126696 |
936 |
Alzheimer's disease |
human |
Male sex |
RF |
|
32043803 |
400 |
Alzheimer's disease |
human |
Depression |
RF |
|
32043803 |
937 |
Alzheimer's disease |
human |
polypharmacy |
RF |
|
32251456 |
938 |
Alzheimer's disease |
human |
inappropriate use anti-dementia drugs |
RF |
|
32251456 |
939 |
Alzheimer's disease |
human |
irregular medication use anti-dementia drugs |
RF |
|
32251456 |
940 |
Alzheimer's disease |
human |
number of functional tooth units (FTU) |
RF |
|
32116259 |
941 |
Alzheimer's disease |
human |
Statin therapy |
PF |
|
32753051 |
942 |
Alzheimer's disease |
human |
coronavirus disease 2019 (COVID-19) |
RF |
|
32715280 |
943 |
Alzheimer's disease |
human |
age at baseline |
RF |
|
32485802 |
944 |
Alzheimer's disease |
human |
daytime napping |
PF |
|
33150399 |
425 |
Alzheimer's disease |
human |
education |
PF |
higher education;more likely to consume colorful fruits and vegetables |
32970519 |
945 |
Alzheimer's disease |
human |
Severe periodontitis with tooth loss |
RF |
|
33124208 |
946 |
Alzheimer's disease |
human |
increasing years of schooling |
PF |
|
33177243 |
947 |
Alzheimer's disease |
human |
pulse pressure (PP) |
RF |
|
32960784 |
400 |
Alzheimer's disease |
human |
Depression |
RF |
|
32003417 |
948 |
Alzheimer's disease |
human |
severe hypoglycaemia |
RF |
|
32870568 |
401 |
Alzheimer's disease |
human |
Diabetes |
RF |
|
32767997 |
480 |
Alzheimer's disease |
human |
Heart disease |
RF |
|
32767997 |
663 |
Alzheimer's disease |
human |
Stroke |
RF |
|
32767997 |
949 |
Alzheimer's disease |
human |
Delirium |
RF |
|
32767997 |
950 |
Alzheimer's disease |
human |
moderate depression |
RF |
healthy-to-MCI/dementia |
33088897 |
506 |
Alzheimer's disease |
human |
hypertension |
PF |
MCI-to-dementia |
33088897 |
951 |
Amyotrophic lateral sclerosis |
human |
lead exposure |
RF |
environmental/occupational |
31578652 |
333 |
Amyotrophic lateral sclerosis |
human |
alcohol consumption |
RF |
|
32196748 |
952 |
Amyotrophic lateral sclerosis |
human |
head trauma |
RF |
|
32019087 |
953 |
Amyotrophic lateral sclerosis |
human |
electric shock |
RF |
|
32019087 |
954 |
Amyotrophic lateral sclerosis |
human |
use of private wells for drinking water |
RF |
|
32019087 |
955 |
Amyotrophic lateral sclerosis |
human |
use of herbicides during gardening |
RF |
|
32019087 |
956 |
Amyotrophic lateral sclerosis |
human |
overall fish consumption |
PF |
|
32019087 |
957 |
Amyotrophic lateral sclerosis |
human |
history of occupation in the agricultural sector |
RF |
|
32331298 |
957 |
Amyotrophic lateral sclerosis |
human |
history of occupation in the agricultural sector |
RF |
|
32331298 |
958 |
Amyotrophic lateral sclerosis |
human |
occupational exposure to Solvents(thinners) |
RF |
|
32331298 |
959 |
Amyotrophic lateral sclerosis |
human |
occupational exposure to Solvents(paint removers) |
RF |
|
32331298 |
960 |
Amyotrophic lateral sclerosis |
human |
occupational exposure to electromagnetic fields |
RF |
|
32331298 |
961 |
Amyotrophic lateral sclerosis |
human |
environmental exposure to electromagnetic fields |
RF |
|
32331298 |
962 |
Amyotrophic lateral sclerosis |
human |
exposure to pesticides |
RF |
Occupational but not environmental exposure,particularly fungicides |
32331298 |
439 |
Amyotrophic lateral sclerosis |
human |
exposure to metals |
RF |
particularly mercur yand selenium |
32331298 |
438 |
Amyotrophic lateral sclerosis |
human |
Exposure to Lead |
RF |
|
32331298 |
963 |
Amyotrophic lateral sclerosis |
human |
antidiabetics |
PF |
|
32097525 |
692 |
Amyotrophic lateral sclerosis |
human |
Use of statins |
RF |
|
32097525 |
429 |
Amyotrophic lateral sclerosis |
human |
environmental exposure to cadmium |
RF |
|
33068316 |
429 |
Amyotrophic lateral sclerosis |
human |
environmental exposure to cadmium |
RF |
|
33068316 |
438 |
Amyotrophic lateral sclerosis |
human |
Exposure to Lead |
RF |
|
33068316 |
438 |
Amyotrophic lateral sclerosis |
human |
Exposure to Lead |
RF |
|
33068316 |
964 |
Amyotrophic lateral sclerosis |
human |
Zinc |
PF |
|
33068316 |
964 |
Amyotrophic lateral sclerosis |
human |
Zinc |
PF |
|
33068316 |
663 |
Amyotrophic lateral sclerosis |
human |
stroke |
RF |
|
32266542 |
965 |
Amyotrophic lateral sclerosis |
human |
lower BMI |
RF |
|
32266542 |
966 |
Amyotrophic lateral sclerosis |
human |
regular physical activity |
RF |
|
32266542 |
967 |
Amyotrophic lateral sclerosis |
human |
gut microbiota |
RF/PF |
butyrate-producing bacteria are less abundant in the gastrointestinal tracts of people with ALS (PALS) |
33135936 |
676 |
Amyotrophic lateral sclerosis |
human |
trauma |
RF |
|
33130429 |
968 |
Amyotrophic lateral sclerosis |
human |
solvents |
RF |
|
33130429 |
969 |
Amyotrophic lateral sclerosis |
human |
diesel/CVD interaction |
RF |
|
33130429 |
970 |
Amyotrophic lateral sclerosis |
human |
trauma/solvents interaction |
PF |
|
33130429 |
968 |
Amyotrophic lateral sclerosis |
human |
solvents |
RF |
|
33130429 |
676 |
Amyotrophic lateral sclerosis |
human |
trauma |
RF |
|
33130429 |
438 |
Amyotrophic lateral sclerosis |
human |
Exposure to Lead |
RF |
|
33130429 |
971 |
Amyotrophic lateral sclerosis |
human |
CVD |
RF |
|
33130429 |
972 |
Amyotrophic lateral sclerosis |
human |
lead/solvents interaction |
PF |
|
33130429 |
973 |
Amyotrophic lateral sclerosis |
human |
Vitamin A |
RF |
higher serum Vitamin A |
32625160 |
974 |
Amyotrophic lateral sclerosis |
human |
Vitamin B2 |
PF |
higher serum Vitamin B2 |
32625160 |
975 |
Amyotrophic lateral sclerosis |
human |
Vitamin B9 |
PF |
higher serum Vitamin B9 |
32625160 |
277 |
Amyotrophic lateral sclerosis |
human |
Vitamin C |
PF |
higher serum Vitamin C |
32625160 |
976 |
Amyotrophic lateral sclerosis |
human |
Exposure to extremely low frequency magnetic fields (ELF-MF) |
RF |
|
32946420 |
952 |
Amyotrophic lateral sclerosis |
human |
Head trauma |
RF |
with significantly greater effects for injuries occurring 10 or more years prior to symptom onset |
33006184 |
977 |
Amyotrophic lateral sclerosis |
human |
severe electrical burns |
RF |
|
33006184 |
978 |
Amyotrophic lateral sclerosis |
human |
Hobbies involving lead |
RF |
Exposures to lead 20 or more years prior to diagnosis had larger effect sizes compared to those occurring more recently. |
33006184 |
979 |
Amyotrophic lateral sclerosis |
human |
Physicians |
RF |
|
32687038 |
980 |
Frontotemporal dementia |
human |
exposure to Aluminum |
RF |
|
33138082 |
981 |
Frontotemporal dementia |
human |
pesticides |
RF |
Insecticides,Herbicides,Fungicides |
33138082 |
982 |
Frontotemporal dementia |
human |
Overall solvents and dyes |
RF |
|
33138082 |
952 |
Frontotemporal dementia |
human |
Head trauma |
RF |
|
33138082 |
983 |
Frontotemporal dementia |
human |
Playing sports |
PF |
|
33138082 |
984 |
Frontotemporal dementia |
human |
football |
RF |
|
33138082 |
985 |
Frontotemporal dementia |
human |
cycling |
RF |
|
33138082 |
986 |
Frontotemporal dementia |
human |
Use of dietary supplements containing selenium |
RF |
|
33138082 |
987 |
Frontotemporal dementia |
human |
Excluding specific neuroprotective supplements |
RF |
after onset of disease |
33138082 |
652 |
Frontotemporal dementia |
human |
smoking |
RF |
Ever smoking |
33138082 |
652 |
Frontotemporal dementia |
human |
smoking |
RF |
Passive smoking exposure |
33138082 |
988 |
Lewy body dementia |
human |
positive family history of dementia or PD |
RF |
|
31771063 |
989 |
Lewy body dementia |
human |
vascular cognitive impairment (VCI) |
RF |
in tremor group and non-tremor group |
32903761 |
400 |
Lewy body dementia |
human |
Depression |
RF |
|
32043803 |
990 |
Multiple System Atrophy |
human |
use of non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) |
PF |
|
31661696 |
990 |
Multiple System Atrophy |
human |
use of non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) |
PF |
Cumulative doses were used to divide observations into tertiles creating 3 groups of equal size (T1–3) based on the consumption in defined daily dose(DDD) with T1 representing the group with the lowest use and T3 the highest. |
31661696 |
990 |
Multiple System Atrophy |
human |
use of non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) |
PF |
Cumulative doses were used to divide observations into tertiles creating 3 groups of equal size (T1–3) based on the consumption in DDDs with T1 representing the group with the lowest use and T3 the highest. |
31661696 |
991 |
Parkinson's Disease |
human |
well water(containing heavy metals and nitrates) |
RF |
Consumption of well water containing heavy metals and nitrates in early life |
32351250 |
992 |
Parkinson's Disease |
human |
Vascular Inflammation:blood-brain barrier(BBB) |
RF |
|
32733633 |
993 |
Parkinson's Disease |
human |
Education? |
PF |
|
32865628 |
506 |
Parkinson's Disease |
human |
Hypertension |
RF |
|
32865628 |
388 |
Parkinson's Disease |
human |
coffee consumption |
PF |
|
32943485 |
652 |
Parkinson's Disease |
human |
smoking |
PF |
|
32943485 |
604 |
Parkinson's Disease |
human |
physical activity |
PF |
|
32943485 |
994 |
Parkinson's Disease |
human |
family history of PD |
RF |
|
32943485 |
995 |
Parkinson's Disease |
human |
dyspepsia |
RF |
|
32943485 |
962 |
Parkinson's Disease |
human |
exposure to pesticides |
RF |
|
32943485 |
996 |
Parkinson's Disease |
human |
oils |
RF |
|
32943485 |
997 |
Parkinson's Disease |
human |
metals |
RF |
|
32943485 |
998 |
Parkinson's Disease |
human |
general anesthesia |
RF |
|
32943485 |