Epidemiological Factors

Epidemiological factors mainly include age, gender, ethnicity, disease, medication, diet, exposure to the environment, smoking, sleep, etc.
The search result for the Risk factor Category "Epidemiological"
A total of 1502 results found based on your keywords
RF_ID Disease Name Species RF_Name Association Phase Condition Year PMID
3543 Alzheimer's Disease Human the assessment of oxidative stress and function parameters in peripheral blood cells,isolated neutrophils and mononuclear cells RF 2018 29375582
311 Creutzfeldt-Jakob disease Human Surgical types Not Related Diagnosis 2009 19193271
316 Creutzfeldt-Jakob disease Human Surgical types Not Related Diagnosis 2009 19193271
4181 Creutzfeldt-Jakob disease Human Surgical types RF Diagnosis 2011 20547628
1119 Creutzfeldt-Jakob disease Human Surgical types PF Diagnosis 2002 12196646
313 Creutzfeldt-Jakob disease Human Surgical types Not Related Diagnosis 2009 19193271
4178 Creutzfeldt-Jakob disease Human Surgical types RF Diagnosis 2011 20547628
4183 Creutzfeldt-Jakob disease Human Surgical types RF Diagnosis 2011 20547628
323 Creutzfeldt-Jakob disease Human Surgical types Not Related Diagnosis Except for brain and vertebral column 1998 9660576
310 Creutzfeldt-Jakob disease Human Surgical types Not Related Diagnosis 2009 19193271
315 Creutzfeldt-Jakob disease Human Surgical types Not Related Diagnosis 2009 19193271
4180 Creutzfeldt-Jakob disease Human Surgical types RF Diagnosis 2011 20547628
1118 Creutzfeldt-Jakob disease Human Surgical types PF Diagnosis 2002 12196646
312 Creutzfeldt-Jakob disease Human Surgical types Not Related Diagnosis 2009 19193271
4177 Creutzfeldt-Jakob disease Human Surgical types RF Diagnosis 2011 20547628
317 Creutzfeldt-Jakob disease Human Surgical types Not Related Diagnosis 2009 19193271
4182 Creutzfeldt-Jakob disease Human Surgical types RF Diagnosis 2011 20547628
322 Creutzfeldt-Jakob disease Human Surgical types Not Related Diagnosis 1998 9660576
309 Creutzfeldt-Jakob disease Human Surgical types Not Related Diagnosis 2009 19193271
314 Creutzfeldt-Jakob disease Human Surgical types Not Related Diagnosis 2009 19193271
4179 Creutzfeldt-Jakob disease Human Surgical types RF Diagnosis 2011 20547628
4184 Creutzfeldt-Jakob disease Human Surgical types RF Diagnosis 2011 20547628
324 Creutzfeldt-Jakob disease Human Surgical types Not Related Diagnosis 1998 9660576
1117 Creutzfeldt-Jakob disease Human Surgical types PF Diagnosis 1998 9660576
2167 Parkinson disease Human Rural living RF 2001 11437458
2927 Parkinson disease Human Rural living RF 2010 21059511
2168 Parkinson disease Human Rural living RF 2001 11437458
2312 Parkinson disease Human Rural living RF 1998 9778597
876 Alzheimer's Disease mice restoring vascular functions(microvascular injury) PF 2021 33892818
282 Amyotrophic Lateral Sclerosis Human Residence Not Related Diagnosis 2017 28851431
1300 Parkinson disease Human Residence PF Diagnosis 1989 2710356
3757 Alzheimer's Disease Human progressive brain energy decline RF 2021 33186671
4171 Creutzfeldt-Jakob disease Human Occupational types RF Diagnosis 1999 10073510
355 Progressive Supranuclear Palsy Human Occupational types Not Related Diagnosis 2009 19864660
4132 Amyotrophic Lateral Sclerosis Human Occupational types RF Diagnosis 1997 9199537
4137 Amyotrophic Lateral Sclerosis Human Occupational types RF Diagnosis 2010 20012543
4118 Amyotrophic Lateral Sclerosis Human Occupational types RF Prognosis 2005 16269579
4291 Parkinson disease Human Occupational types RF Diagnosis 1989 2710356
4168 Creutzfeldt-Jakob disease Human Occupational types RF Diagnosis 2009 19144172
4123 Amyotrophic Lateral Sclerosis Human Occupational types RF Diagnosis 1986 3962963
4173 Creutzfeldt-Jakob disease Human Occupational types RF Diagnosis 1999 10073510
4199 Multiple System Atrophy Human Occupational types RF Diagnosis 2008 18307243
4134 Amyotrophic Lateral Sclerosis Human Occupational types RF Diagnosis 2014 24246552
4115 Amyotrophic Lateral Sclerosis Human Occupational types RF Diagnosis 2007 17923612
4120 Amyotrophic Lateral Sclerosis Human Occupational types RF Prognosis 2005 16269579
1116 Amyotrophic Lateral Sclerosis Human Occupational types PF Diagnosis 2019 31155341
4170 Creutzfeldt-Jakob disease Human Occupational types RF Diagnosis 1999 10073510
4131 Amyotrophic Lateral Sclerosis Human Occupational types RF Diagnosis 2010 20847462
297 Creutzfeldt-Jakob disease Human Occupational types Not Related Diagnosis 1998 9660576
4117 Amyotrophic Lateral Sclerosis Human Occupational types RF Diagnosis 2018 29941657
4290 Parkinson disease Human Occupational types RF Diagnosis 1989 2710356
1113 Amyotrophic Lateral Sclerosis Human Occupational types PF Diagnosis 2018 29941657
4172 Creutzfeldt-Jakob disease Human Occupational types RF Diagnosis 1999 10073510
4064 Alzheimer's Disease Human Occupational types RF Diagnosis 2003 12541276
4138 Amyotrophic Lateral Sclerosis Human Occupational types RF Diagnosis 2019 31155341
4119 Amyotrophic Lateral Sclerosis Human Occupational types RF Prognosis 2005 16269579
4169 Creutzfeldt-Jakob disease Human Occupational types RF Diagnosis 1999 10073510
1301 Parkinson disease Human Occupational types PF Diagnosis 1989 2710356
4130 Amyotrophic Lateral Sclerosis Human Occupational types RF Prognosis a Electric occupations (1990 US Bureau of Census Codes): Electrical and electronic engineers (55); electrical and electronic technicians (213); broadcast equipment operators (228); electronic repairers; communications and industrial equipment (523); data processing equipment repairers (525); househo 2015 24917188
4135 Amyotrophic Lateral Sclerosis Human Occupational types RF Diagnosis 2010 20433412
4116 Amyotrophic Lateral Sclerosis Human Occupational types RF Diagnosis 2018 29941657
1780 Alzheimer's Disease Human non-cancer chronic pain conditions (NCPCs) RF 2021 34351824
3840 Parkinson disease Human Leukocytosis RF 2021 34058741
3788 Amyotrophic Lateral Sclerosis Human Industrial airborne chemical releases RF Diagnosis 2021 34921938
3899 Alzheimer's Disease mice Endogenous melatonin reduction (EMR) RF Diagnosis 2023 35619714
1540 Alzheimer's Disease Human Diabetic retinopathy (DR) RF Diagnosis persons with diabetes 2022 35068460
2014 Parkinson disease Human chronic obstructive pulmonary disease RF Prognosis 2021 33219665
930 Huntington's disease (HD) mice environmental enrichment (EE) PF Diagnosis 2023 37628801
3993 Amyotrophic Lateral Sclerosis Human armed forces RF Diagnosis 2023 36476139
3992 Amyotrophic Lateral Sclerosis Human agriculture/breeding RF Diagnosis 2023 36476139
2854 Motor Neuron Disease Human cleaning products RF Diagnosis 2022 35318275
3121 Motor Neuron Disease Human disinfectants RF Diagnosis 2022 35318275
2629 Motor Neuron Disease Human textile fibres RF Diagnosis 2022 35318275
2547 Motor Neuron Disease Human petrol/diesel fuel RF Diagnosis 2022 35318275
3025 Motor Neuron Disease Human methyl bromide RF Diagnosis 2022 35318275
2911 Motor Neuron Disease Human Fumigants RF Diagnosis 2022 35318275
1805 Amyotrophic Lateral Sclerosis Human organic/chlorinated solvents RF Diagnosis 2023 37993052
472 Amyotrophic Lateral Sclerosis Human Residential air selenium PF Diagnosis 2023 37993052
1890 Amyotrophic Lateral Sclerosis Human HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase (HMGCR) inhibitors RF Diagnosis 2023 37688479
3977 Amyotrophic Lateral Sclerosis mice Sublethal enteroviral infection RF Diagnosis 2022 35022041
1532 Amyotrophic Lateral Sclerosis Human neutrophil-derived metrics RF Diagnosis 2023 37554051
1527 Amyotrophic Lateral Sclerosis Human neutrophil-derived metrics RF Diagnosis 2023 37554051
1526 Amyotrophic Lateral Sclerosis Human neutrophil levels RF Diagnosis 2023 37554051
3974 Parkinson disease Human toxicant N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine quinone (6PPD-Q) RF Diagnosis 2023 38147746
3973 Parkinson disease Human ganglion cell-inner plexiform layer complex (GCIPL) thickness RF Diagnosis 2023 38104911
3972 Parkinson disease Human high mobility group box-1 (HMGB1) levels RF Diagnosis 2023 38104911
1601 Parkinson disease Human adhesive capsulitis of the shoulder (ACS) RF Diagnosis 2023 37428415
1664 Parkinson disease Human presence of cirrhosis RF Diagnosis infection with hepatitis C virus (HCV) 2023 36872452
902 Alzheimer's Disease Human Glucagon-like peptide 1 (GLP-1) agonists PF Prognosis 2023 35128745
442 Alzheimer's Disease Human metformin PF Diagnosis Type 2 diabetes mellitus (T2DM) 2022 36109050
3971 Parkinson disease Human serum levels of selenoprotein P (SelP) RF Diagnosis 2023 37995510
3970 Parkinson disease Human serum levels of Selenium (Se) RF Diagnosis 2023 37995510
3969 Parkinson disease Human urine protein levels RF Diagnosis 2023 38174461
3968 Parkinson disease Human creatinine levels RF Diagnosis 2023 38174461
3967 Parkinson disease Human blood urea nitrogen levels RF Diagnosis 2023 38174461
3070 Parkinson disease Human perivascular space (PVS) RF Diagnosis 2023 36097211
2436 Parkinson disease Human paraventricular white matter hyperintensity (PVH) RF Diagnosis 2023 36097211
2156 Parkinson disease Human cerebral small vessel disease (cSVD) RF Diagnosis 2023 36097211
3966 Parkinson disease Human neutrophil/lymphocyte ratio RF Diagnosis 2023 37159450
3965 Parkinson disease Human insulin-like growth factor 1 (IGF-1) RF Diagnosis 2023 37159450
3962 Parkinson disease Human dysthyroidism RF Diagnosis 2023 37294324
1506 Parkinson disease Human retinal age gap RF Diagnosis deep learning (DL) model trained on 19,200 fundus images of 11,052 chronic disease-free participants was used to predict retinal age 2022 35352798
2528 Parkinson disease Human anticholinergic drugs RF Diagnosis 2023 37357543
1661 Parkinson disease Human affective disorders RF Diagnosis incident PD over 15 years 2022 35752216
1668 Parkinson disease Human affective disorders RF Diagnosis incident PD over 16 years 2022 35752216
1652 Parkinson disease Human affective disorders RF Diagnosis incident PD over 17 years 2022 35752216
1649 Parkinson disease Human affective disorders RF Diagnosis incident PD over 18 years 2022 35752216
2517 Parkinson disease Human sleep disorders RF Diagnosis 2022 36037514
1791 Neurodegenerative diseases Human sleep disorders RF Diagnosis 2023 37269705
1772 Neurodegenerative diseases Human sleep disorders RF Diagnosis comorbid depression 2023 37269705
1667 Parkinson disease Human sleep disorders RF Diagnosis incident PD over 14 years 2022 35752216
925 Parkinson disease Human apolipoprotein A1 (Apo A1) PF Diagnosis 2022 35723114
1709 Parkinson disease Human obsessive-compulsive disorder (OCD) RF Diagnosis 2022 35980783
1691 Parkinson disease Human obsessive-compulsive disorder (OCD) RF Diagnosis 2022 35980783
764 Parkinson disease Human gout PF Diagnosis 2022 35504516
1468 Parkinson disease Human antidepressants RF Diagnosis 2022 35748105
2970 Parkinson disease Human tremor RF Diagnosis even 5 to 10 years before diagnosis 2023 36342675
1948 Parkinson disease Human potential inflammatory component RF Diagnosis 2023 36342675
1994 Parkinson disease Human gastrointestinal disorders RF Diagnosis 2023 36342675
2002 Parkinson disease Human gastrointestinal disorders RF Diagnosis 2023 36342675
1902 Parkinson disease Human skin disorders RF Diagnosis 2023 36342675
2012 Parkinson disease Human skin disorders RF Diagnosis 2023 36342675
2018 Parkinson disease Human changes of skin sensation RF Diagnosis 2023 36342675
1950 Parkinson disease Human migraine RF Diagnosis 2023 36342675
2968 Parkinson disease Human schizophrenia RF Diagnosis 2023 36342675
2923 Parkinson disease Human schizophrenia RF Diagnosis even 5 to 10 years before diagnosis 2023 36342675
2150 Parkinson disease Human sleep apnea RF Diagnosis 2023 37185062
2089 Parkinson disease Human sleep apnea RF Diagnosis 2023 36342675
1792 Parkinson disease Human sleep apnea RF Diagnosis 2023 37269705
2525 Parkinson disease Human anosmia RF Diagnosis 2023 36342675
920 Alzheimer's Disease Human gut metabolites PF Diagnosis 2022 35275534
3950 Amyotrophic Lateral Sclerosis Human gut metabolites RF Diagnosis 2022 35275534
921 Parkinson disease Human gut metabolites PF Diagnosis 2022 35275534
919 Parkinson disease Human LRRK2 inhibition PF Treatment 2022 35675433
1578 Parkinson disease Human gait speed RF Diagnosis 2023 36912851
1642 Parkinson disease Human Exhaustion RF Diagnosis 2023 36912851
3945 Alzheimer's Disease Human multimorbidity RF Diagnosis 2023 37950963
3942 Alzheimer's Disease Human West Nile virus (WNV) RF Diagnosis 2023 37734269
918 Alzheimer's Disease Human absence of impairment with prior daily functioning PF Diagnosis 2023 37454558
917 Alzheimer's Disease Human non-Hispanic White PF Diagnosis 2023 37454558
3940 Alzheimer's Disease Human impaired patient ability in the use of telephone RF Diagnosis 2023 37454558
3939 Alzheimer's Disease Human hearing impairment RF Diagnosis 2023 37454558
807 Alzheimer's Disease Human cardioembolic stroke [CES] PF Diagnosis 2023 37665672
3093 Alzheimer's Disease Human cognitive decline RF Prognosis 2022 35850031
3933 Alzheimer's Disease mice body temperature RF Diagnosis 2022 35851831
1349 Alzheimer's Disease Human Radon exposure RF Diagnosis 2023 36495187
1375 Parkinson disease Human Radon exposure RF Diagnosis 2023 36495187
3932 Alzheimer's Disease Human glucose RF Diagnosis 2023 35319157
3931 Alzheimer's Disease mice Sepsis RF Diagnosis 2023 37452088
1458 Alzheimer's Disease Human insulin RF Diagnosis Type 2 diabetes mellitus (T2DM) 2023 37095270
1465 Alzheimer's Disease Human Pioglitazone RF Diagnosis Type 2 diabetes mellitus (T2DM) 2023 37095270
429 Alzheimer's Disease Human Cataract surgery PF Prognosis 2021 34870676
409 Alzheimer's Disease Human Cataract surgery PF Diagnosis 2023 35940935
1586 Alzheimer's Disease Human Nonsurgical cataract RF Diagnosis 2023 35940935
1420 Alzheimer's Disease Human limitation in physical function RF Diagnosis Main exposure variables were difficulty with activities of daily living, mobility, large muscle strength, gross motor and upper limb activities. 2022 35441254
3911 Alzheimer's Disease mice Knee osteoarthritis (OA) RF Diagnosis 2023 36593507
483 Alzheimer's Disease Human inpatient status PF Prognosis 2022 35196953
1459 Parkinson disease Human anxiolytics RF Diagnosis 2022 35748105
484 Alzheimer's Disease Human anxiolytics PF Prognosis 2022 35196953
1831 Alzheimer's Disease Human hypertension medication RF Diagnosis 2022 35196953
1836 Alzheimer's Disease Human antipsychotics RF Diagnosis 2022 35196953
3909 Alzheimer's Disease Human Gait and/or balance disturbances RF Diagnosis 2023 37386779
1775 Alzheimer's Disease Human Muscle relaxant RF Diagnosis 2022 36641664
1779 Alzheimer's Disease Human Muscle relaxant RF Diagnosis 2022 36641664
1778 Alzheimer's Disease Human Muscle relaxant RF Diagnosis 2022 36641664
1508 Alzheimer's Disease Human residential density RF Diagnosis 2023 36894118
1908 Alzheimer's Disease Human Thyroid dysfunction RF Diagnosis 2022 35321339
1958 Alzheimer's Disease Human Thyroid dysfunction RF Diagnosis 2022 35321339
1900 Alzheimer's Disease Human Thyroid dysfunction RF Diagnosis 2022 35321339
3903 Alzheimer's Disease Human chronic vascular lesions RF Diagnosis Traumatic brain injury (TBI) 2022 34966025
3902 Alzheimer's Disease Human post-traumatic amnesia RF Diagnosis Traumatic brain injury (TBI) 2022 34966025
3901 Alzheimer's Disease Human Transgender Adults RF Diagnosis 2022 35324265
2291 Alzheimer's Disease Human working status RF Diagnosis 2022 36479845
2516 Alzheimer's Disease Human working status RF Diagnosis 2022 36479845
2715 Alzheimer's Disease Human working status RF Diagnosis 2022 36479845
2253 Alzheimer's Disease Human Thyroid diseases RF Diagnosis 2022 35700125
2249 Alzheimer's Disease Human thyroid diseases RF Diagnosis 2022 35700125
3897 Alzheimer's Disease mice Myelin dysfunction RF Diagnosis 2023 37258678
3896 Alzheimer's Disease Human total tau (t-tau) RF Diagnosis 2023 34494715
3895 Alzheimer's Disease Human plasma glial fibrillary acidic protein (GFAP) RF Diagnosis 2023 34494715
3544 Alzheimer's Disease Human a protective response to proteostatic stress, directed by the NRF1-sMAF complex RF people carrying the risk (A) allele of rs667897 2018 29179108
3545 Alzheimer's Disease Human accumulation of p16(INK4a)-positive senescent astrocytes RF 2012 22984612
3547 Amyotrophic Lateral Sclerosis mice age-related decreases in ADAR2(adenosine deaminase acting on RNA 2) activity RF 2012 22916266
3548 Alzheimer's Disease mice age-related increase in chemokine CCL11 RF antagonizing CCR3 may bring therapeutic benefits to?AD 2017 27878757
774 Parkinson disease Human alpha-synuclein (NACP-Rep1) PF 2005 15670652
3741 Alzheimer's Disease Human amyloid beta (Aβ) misfolding RF 2021 33614887
2537 Alzheimer's Disease Human Amyloid-β (Aβ)(42) RF 2012 21955816
3551 Alzheimer's Disease Human annexin A5 RF 2013 23576984
3540 Alzheimer's Disease Human anti-AT1R RF 2015 26401573
3552 Frontotemporal Dementia Human apo(a) low molecular weight (MW RF 2003 14665416
3554 Alzheimer's Disease Human apoE protein activity RF 1995 7672107
3553 Amyotrophic Lateral Sclerosis Human APOE(protein) RF 2002 11940705
3557 Amyotrophic Lateral Sclerosis Human Ataxin-2 intermediate-length polyglutamine expansions RF 2011 21292779
3132 Alzheimer's Disease Human Aβ misfolding(measured in blood plasma) RF 2020 31611055
3558 Alzheimer's Disease Human beta-amyloid (Abeta) accumulation RF 2018 29592889
2296 Alzheimer's Disease Human beta-amyloid precursor protein (APP) processing RF 1997 9041854
858 Alzheimer's Disease Caenorhabditis elegans betaine PF both the presence and absence of 1 mM homocysteine; independent of the remethylation pathway but requires the transsulfuration pathway mediated by cystathionine-β-synthase 2018 30065790
3559 Alzheimer's Disease Human Bleomycin hydrolase (BLH) RF 2010 20308784
3561 Alzheimer's Disease Human Branched-chain amino acids (BCAAs) RF 2018 29802157
1671 Parkinson disease Human calcium channel blocker RF Diagnosis 2021 33647030
3562 Alzheimer's Disease mice CB1 receptor desensitization RF Seven-month-old male 3xTg-AD mice 2018 29865071
3709 Alzheimer's Disease mice CD22 RF 2021 34140954
481 Alzheimer's Disease Human cerebrospinal fluid (CSF) Aβ42 PF patients with negative amyloid PET 2021 33667602
482 Alzheimer's Disease Human cerebrospinal fluid (CSF) Aβ42 PF patients with negative amyloid PET 2021 33667602
3566 Alzheimer's Disease Human Complement Receptor 1 (CR1) Density RF 2018 30044434
3569 Parkinson disease Human C-reactive protein (CRP) RF 2019 31057478
3568 Parkinson disease Human C-reactive protein (CRP) RF 2019 31057478
1868 Alzheimer's Disease Human C-reactive protein (CRP) RF Diagnosis 2023 34538509
3570 Parkinson disease Human C-reactive protein (CRP) RF 2019 31057478
3571 Alzheimer's Disease Human CSF AβPET(amyloid beta brain PET imaging) RF Associated with AD progression 2018 29982466
3572 Alzheimer's Disease Human CSF Tau(cerebrospinal fluid tau) and P-tau(phosphorylated tau) RF Associated with AD progression 2018 29982466
3573 Alzheimer's Disease Human decreased expression of FERMT2 RF 2016 27215977
1752 Alzheimer's Disease Human decreasing Aβ1-42 rates RF 2018 30250861
890 Neurodegenerative diseases mice Deferoxamine PF 2021 33788818
3575 Alzheimer's Disease Human depression-related monoaminergic systems RF including serotonin and noradrenaline 2019 29685068
3576 Parkinson disease Human disturbance of the plasmatic rate of Cu RF 2013 23868039
3578 Amyotrophic Lateral Sclerosis Human dysregulation modulation of proteasome activity RF 2014 24450587
883 Alzheimer's Disease Human Fibroblast Growth Factor 21 (FGF21) PF 2021 33131010
2346 Alzheimer's Disease Human Fibroblast Growth Factor 21 (FGF21) RF 2021 33850218
3541 Alzheimer's Disease Human free copper RF 2013 23760784
859 Alzheimer's Disease mice glucose regulation PF 2019 31034991
1581 Alzheimer's Disease Human glycated hemoglobin (HbA1c) RF Model II: adjusted for age, sex, FPG,HbA1c, insured amount and insured unit (see Table 1), smoking, alcohol consumption, duration of diabetes, type of hypoglycemic drug, hypertension drug treatment, and obesity 2017 28705834
1557 Alzheimer's Disease Human glycated hemoglobin (HbA1c) RF Model IV: adjusted for PFG CV and HbA1c CV along with all other confounders in model III 2017 28705834
1611 Alzheimer's Disease Human glycated hemoglobin (HbA1c) RF Model I: adjusted for age and sex 2017 28705834
1576 Alzheimer's Disease Human glycated hemoglobin (HbA1c) RF Model III: adjusted for CAD, CHF, stroke, cancer, hyperlipidemia, hypertension, atrial fibrillation, chronic hepatitis, COPD, and hypoglycemia along with all other confounders in model II 2017 28705834
3583 Alzheimer's Disease Human H4K16ac enrichment RF related to aging 2018 29507413
3585 Alzheimer's Disease Human High CSF(cerebrospinal fluid) MCP-1(monocyte chemoattractant protein 1) RF Associated with AD progression 2018 29982466
3590 Alzheimer's Disease Human IL-17A/IL-23 axis RF 2018 30081688
861 Alzheimer's Disease Human increased expression of NUP160 PF 2016 27215977
3592 Alzheimer's Disease Human increased fibrillar amyloid-{beta} RF individuals with a family history of late-onset Alzheimer's;particularly in persons with an AD mother 2010 20231448
3593 Alzheimer's Disease Human increased gene dosage of MIR138-2 RF 2019 30909216
3675 Alzheimer's Disease Human indices of HbA1c variability RF 2020 32870568
3596 Alzheimer's Disease mice inhibition of angiotensin-converting enzyme (ACE) activity RF 2019 31072831
3598 Alzheimer's Disease Human intracellular iron accumulation RF 2014 24199959
887 Alzheimer's Disease mice Irisin PF Treatment 2021 33768561
3599 Alzheimer's Disease Human ischemia/HIF-1α RF 2014 24478626
1452 Parkinson disease Human levodopa equivalent dose (LED) RF Diagnosis 2021 33505652
1765 Alzheimer's Disease Human lifetime-acquired loss of chromosome Y (LOY) RF in blood cells 2016 27231129
3864 Parkinson disease Human Lipoprotein-Associated Phospholipase A2(Lp-PLA2) RF Diagnosis 2021 33958981
863 Parkinson disease Human lncRNA AK021630 PF 2017 27151187
3601 Parkinson disease Human lncRNA AL049437 RF 2017 27151187
3603 Parkinson disease Human Loss of aromatase cytochrome P450 function RF 2008 18063054
3609 Alzheimer's Disease mice mammalian target of rapamycin (mTOR) RF Tg2576 mice 2018 29729422
2656 Alzheimer's Disease Human Methionine synthase RF 2003 12876480
2718 Alzheimer's Disease Human Methionine synthase RF 2003 12876480
2795 Alzheimer's Disease Human Methionine synthase RF 2003 12876480
2699 Alzheimer's Disease Human Methionine synthase RF 2003 12876480
3827 Parkinson disease Human molecular architecture of dopaminergic networks RF Diagnosis 2021 33198485
2341 Alzheimer's Disease Human mtDNA sub-haplogroup H5 RF in particular for females and independently from the APOE genotype 2010 20700462
3616 Amyotrophic Lateral Sclerosis Human mutations in neurofilaments RF 2006 16084104
3739 Alzheimer's Disease Human MWF; an in vivo marker of myelin content RF 2021 33638111
3617 Alzheimer's Disease Human Myeloperoxidase(MPO) polymorphism RF 1999 9918702
893 Parkinson disease rat Naringenin (NAR) PF Treatment Paraquat (PQ); PQ-induced neurotoxicity and neurodegeneration 2021 34655599
3618 Amyotrophic Lateral Sclerosis Human neuronal apoptosis inhibitory protein RF 2018 29311650
885 Alzheimer's Disease mice Non-saponin fraction with rich polysaccharide (NFP) PF 2021 33422674
864 Alzheimer's Disease mice Pantoea agglomerans-derived lipopolysaccharide (LPSp) PF fed a high-fat diet, oral administration of LPSp at 0.3 or 1 mg/kg body weight.day for 18 weeks 2018 29856882
3620 Alzheimer's Disease Human pathogenic mutations in CSF1R TK domain RF in concert with TREM2, TYROBP, and GRN 2018 29544907
3753 Alzheimer's Disease Human perfluorooctane sulfonate (PFOS) RF in older adults with normal kidney function 2021 33068581
3700 Alzheimer's Disease mice perfluorooctane sulfonate (PFOS) RF 2021 34224775
3782 Amyotrophic Lateral Sclerosis Human perivascular fibroblast RF Diagnosis 2021 33859435
3813 Lewy Body Disease Human periventricular white matter hyperintensities (PWMH) RF Diagnosis 2021 34366356
3802 Lewy Body Disease Human periventricular white matter hyperintensities (PWMH) RF 2021 34366356
3621 Amyotrophic Lateral Sclerosis Human perturbations of the ER proteostasis network RF 2015 25913742
3765 Alzheimer's Disease Human plasma phosphorylated tau181 (p-tau181) RF 2021 33419453
3624 Alzheimer's Disease mice plasmin (PL) RF Tg6799 transgenic mice (referred to as AD mice) are double-transgenic for human APP/Presenilin 1 2018 30254165
882 Alzheimer's Disease rat propylparaben (PPB) PF traumatic brain injury (TBI) 2021 33185606
889 Chronic Traumatic Encephalopathy mice PUFAs (n-3 polyunsaturated fatty acids) PF Prognosis 2021 33913741
3626 Alzheimer's Disease Human self-assembly of the Apolipoprotein E4 RF impacts on ε4/ε4 individuals more severely than those with ε3/ε4 2019 31051176
3631 Frontotemporal Dementia Human SORT1(the neuronal receptor for granulin) RF 2018 29555433
3633 Dementia with Lewy bodies Human the Casp2-generated tau fragment Δtau314 RF 2019 31362787
891 Parkinson disease Human Transferrin/Transferrin Receptor 2 (TfR2) PF Treatment significantly more pronounced in females rather than in males 2021 33323945
772 Alzheimer's Disease Human Trunk fat‐free mass PF 2021 33718584
3092 Parkinson disease Human White matter hyperintensities (WMH) RF Diagnosis 2023 36097211
3830 Parkinson disease Human White matter hyperintensities (WMH) RF Prognosis higher levels of both WMH and indices of cerebrovascular disease pathologies in aging brains 2021 34724033
3692 Alzheimer's Disease Human White matter hyperintensities (WMH) RF All patients were Aβ-positive (Aβpos-AD) 2021 34322985
2822 Parkinson disease Human White matter hyperintensities (WMH) RF Diagnosis 2021 33782518
3639 Alzheimer's Disease Human White matter hyperintensities(WMH) load RF 2019 30678723
694 Alzheimer's Disease Human α-synuclein rs356182 variants PF 2018 30598082
2159 Alzheimer's Disease Human African ancestry RF 2017 28369008
3768 Alzheimer's Disease Human Age RF 2021 34499125
1530 Alzheimer's Disease Human Age RF 2020 32485802
1507 Alzheimer's Disease Human Age RF in females 2015 26343475
1921 Alzheimer's Disease Human Age RF in patients after spine surgery 2010 20375503
1832 Alzheimer's Disease Human Age RF Diagnosis 2022 35196953
3376 Alzheimer's Disease Human Age RF 2011 22526079
1943 Alzheimer's Disease Human Age RF 2015 25624416
1879 Alzheimer's Disease Human Age RF 2013 22976076
3748 Alzheimer's Disease Human Age RF 2021 33009037
1584 Alzheimer's Disease Human Age RF after Hemodialysis Initiation 2018 30093374
3875 Parkinson disease Human Age RF Diagnosis 2021 33515623
3378 Parkinson disease rhesus monkey Age RF 2011 21587290
1898 Parkinson disease Human Age RF Diagnosis 2023 37357543
1663 Alzheimer's Disease Human Age RF after Hemodialysis Initiation 2018 30093374
3745 Alzheimer's Disease Human Age RF 2021 32852053
1512 Alzheimer's Disease Human Age RF 2014 24489845
1440 Alzheimer's Disease Human Age RF people with mild cognitive impairment (MCI) 2011 21518614
3375 Alzheimer's Disease Human Age RF 2019 31058682
1660 Alzheimer's Disease Human Age RF after Hemodialysis Initiation 2018 30093374
1878 Alzheimer's Disease Human Age RF 2021 33850218
1929 Alzheimer's Disease Human Age RF 2010 20016220
3377 Amyotrophic Lateral Sclerosis rat Age RF 2019 30873018
3730 Alzheimer's Disease Human Age RF 2021 33686543
1639 Alzheimer's Disease Human Age RF after Hemodialysis Initiation 2018 30093374
838 Parkinson disease Human Age PF GCH1 genotype T allele carries 2017 27871051
2119 Parkinson disease Human Age RF 2007 17884509
3374 Alzheimer's Disease Human Age RF 2015 25401488
1704 Alzheimer's Disease Human Age RF 2017 28806610
2721 Alzheimer's Disease Human age in first degree relatives RF age of 90 in first degree relatives 1993 8411049
795 Alzheimer's Disease Human Asian ethnic PF 2021 33554910
2033 Alzheimer's Disease Human Black ethnic RF 2021 33554910
3448 Alzheimer's Disease Human Gender RF 2016 27105335
1634 Alzheimer's Disease Human Gender RF 2017 28806610
1539 Alzheimer's Disease Human Gender RF 2014 24489845
3146 Parkinson disease Human Gender RF 2010 20111594
2789 Alzheimer's Disease Human Gender RF 2010 20016220
3449 Alzheimer's Disease Human Gender RF 2011 22526079
698 Amyotrophic Lateral Sclerosis Human Gender PF 2016 27065942
2901 Alzheimer's Disease Human Gender RF 2015 25624416
1517 Alzheimer's Disease Human Gender RF after Hemodialysis Initiation 2018 30093374
3769 Alzheimer's Disease Human female sex RF 2021 34499125
3795 Frontotemporal Dementia Human female sex RF Prognosis 2021 34921446
3457 Alzheimer's Disease Human higher age among senior citizens in urban communities RF 2019 31286894
1345 Alzheimer's Disease Human Male sex RF 2021 33681711
1342 Alzheimer's Disease Human Male sex RF 2021 33681711
1344 Alzheimer's Disease Human Male sex RF 2021 33681711
1565 Amyotrophic Lateral Sclerosis Human Male sex RF Diagnosis UK 2021 34675682
3964 Parkinson disease Human Male sex RF Diagnosis 2023 37159450
3677 Alzheimer's Disease Human Male sex RF 2020 32043803
3983 Amyotrophic Lateral Sclerosis Human Male sex RF Diagnosis 2023 37466098
1343 Alzheimer's Disease Human Male sex RF 2021 33681711
754 Alzheimer's Disease Human Native American ancestry PF 2017 28369008
1768 Alzheimer's Disease Human Nonmarried RF 2015 25401488
1428 Motor Neuron Disease Human number of children RF number of children:3 1991 1745327
1946 Alzheimer's Disease Human older age RF Diagnosis 2023 37182880
1647 Amyotrophic Lateral Sclerosis Human older age RF Diagnosis UK 2021 34675682
3984 Amyotrophic Lateral Sclerosis Human older age RF Diagnosis 2023 37466098
2883 Alzheimer's Disease Human older age RF Prognosis 2022 35850031
1913 Alzheimer's Disease Human older age RF 2020 33126696
3956 Parkinson disease Human older age RF Diagnosis 2022 34758470
730 Amyotrophic Lateral Sclerosis Human Race PF other 2016 27065942
3746 Alzheimer's Disease Human Race RF 2021 31948505
2148 Amyotrophic Lateral Sclerosis Human Race RF AA 2016 27065942
1626 Alzheimer's Disease Human Race RF after Hemodialysis Initiation 2018 30093374
1628 Alzheimer's Disease Human Race RF after Hemodialysis Initiation 2018 30093374
2980 Tourette Syndrome Human second-degree relatives RF 2015 26083307
2791 Tourette Syndrome Human third-degree relatives RF 2015 26083307
3796 Frontotemporal Dementia Human age of onset RF Prognosis 2021 34921446
1414 Tuberous sclerosis complex Human age of onset RF 2009 20113608
1731 Parkinson disease Human Ankylosing spondylitis (AS) RF NSAIDs used for AS control have some protective effects against PD 2021 34602503
1635 Parkinson disease Human Ankylosing spondylitis (AS) RF NSAIDs used for AS control have some protective effects against PD 2021 34602503
3863 Parkinson disease Human Appendicitis-like lesions RF Diagnosis 2021 33876851
3386 Dementia with Lewy bodies Human Arterial hypertension (AH) RF 2011 20965516
647 Alzheimer's Disease Human Arthritis PF 1990 2146525
600 Amyotrophic Lateral Sclerosis Human Arthritis PF 2016 27065942
454 Alzheimer's Disease Human Atherosclerotic heart disease PF after Hemodialysis Initiation 2018 30093374
3387 Tuberous sclerosis complex Human autistic features RF 2017 28721058
3883 Tourette Syndrome Human autoimmune disease RF Diagnosis 2021 33479207
2913 Tuberous sclerosis complex Human bilateral angiomyolipoma (AML) RF Diagnosis 2021 33517888
2895 Parkinson disease Human Bipolar disorder (BD) RF Diagnosis 2023 36342675
2892 Parkinson disease Human Bipolar disorder (BD) RF Diagnosis even 5 to 10 years before diagnosis 2023 36342675
3865 Parkinson disease Human Bipolar disorder (BD) RF Prognosis 2021 33927683
2202 Parkinson disease Human Bipolar disorder (BD) RF Diagnosis 2021 33075191
444 Alzheimer's Disease Human Cancer PF after Hemodialysis Initiation 2018 30093374
723 Alzheimer's Disease Human Cancer PF Cancer History(Cancer survivors) 2017 28035936
425 Alzheimer's Disease Human Cancer PF 2018 30906403
3393 Alzheimer's Disease Human cardiovascular disease (CVD) RF 2018 30149459
1988 Amyotrophic Lateral Sclerosis Human cardiovascular disease (CVD) RF 2021 33130429
1986 Amyotrophic Lateral Sclerosis Human cardiovascular disease (CVD) RF Diagnosis 2021 33130429
3906 Frontotemporal Dementia Human cardiovascular disease (CVD) RF Diagnosis 2022 35767471
2374 Parkinson disease Human Carotid plaques RF 2021 34033182
635 Alzheimer's Disease Human Cataract PF 1990 2146525
1692 Alzheimer's Disease Human cerebrovascular disease RF 2017 28806610
3395 Alzheimer's Disease Human cerebrovascular disease RF Cerebrovascular Alterations 2018 30355253
3880 Progressive Supranuclear Palsy Human cerebrovascular disease RF Diagnosis 2021 33967937
1480 Alzheimer's Disease Human cerebrovascular disease RF 2021 33726788
616 Amyotrophic Lateral Sclerosis Human COPD(chronic obstructive pulmonary disease) PF 2016 27065942
1351 Alzheimer's Disease Human coronary heart disease (CHD) RF 2021 33742562
3862 Parkinson disease Human coronavirus disease 2019 (COVID-19) RF Diagnosis 2021 33942924
3823 Parkinson disease Human coronavirus disease 2019 (COVID-19) RF Prognosis PD patients with severe COVID-19 2021 33392827
3680 Alzheimer's Disease Human coronavirus disease 2019 (COVID-19) RF 2020 32715280
3752 Alzheimer's Disease Human cytomegalovirus (CMV) RF 2021 33094810
2866 Creutzfeldt-Jakob disease Human Dementia in family RF 1988 3066847
1475 Alzheimer's Disease Human depression or cerebrovascular disease(CVD) RF 2021 33726788
2094 Parkinson disease Human Diabetes RF Diagnosis 2021 33492248
1603 Alzheimer's Disease Human Diabetes RF 2020 32767997
3929 Alzheimer's Disease Human Diabetes RF Prognosis 2023 36453775
2561 Alzheimer's Disease Human Diabetes RF 2018 29971140
3963 Parkinson disease Human Diabetes RF Diagnosis 2023 37294324
1967 Parkinson disease Human Diabetes RF Diagnosis 2023 36342675
670 Amyotrophic Lateral Sclerosis Human Diabetes PF Adjusted for socioeconomic status, prior chronic obstructive pulmonary disease, marital status, and residence at amyotrophic lateral sclerosis diagnosis. 2015 26030836
3636 Alzheimer's Disease Human Diabetes RF 2013 23478310
1616 Alzheimer's Disease Human Diabetes RF 2004 15148141
1377 Alzheimer's Disease Human Diabetes RF 2018 29606955
2343 Parkinson disease Human Diabetes RF 2007 17251276
3415 Alzheimer's Disease Human Diabetes RF people with mild memory impairment/no dementia (MMI/ND) 2011 21205364
3879 Progressive Supranuclear Palsy Human Diabetes RF Diagnosis 2021 33967937
1503 Parkinson disease Human Diabetes RF Diagnosis 2023 36692249
3034 Parkinson disease Human Diabetes RF 2009 19467671
1367 Alzheimer's Disease Human Diabetes RF 2015 26495049
2277 Parkinson disease Human Diabetes RF Diagnosis 2021 33492248
2546 Dementia with Lewy bodies Human Diabetes RF 2018 29971140
1627 Alzheimer's Disease Human Diabetes RF 2014 24489845
3007 Alzheimer's Disease Human Diabetes RF a risk factor for MCI progressing into AD 2016 27729793
2093 Alzheimer's Disease Human Diabetes RF Diagnosis 2022 34806607
1498 Alzheimer's Disease Human Diabetes RF 2021 32996171
2458 Alzheimer's Disease Human Diabetes RF Diagnosis 2022 35587456
669 Amyotrophic Lateral Sclerosis Human Diabetes PF Unadjusted 2015 26030836
3635 Alzheimer's Disease Human Diabetes RF 2018 30112972
686 Amyotrophic Lateral Sclerosis Human Diabetes PF Adjusted for socioeconomic status, prior chronic obstructive pulmonary disease, marital status, and residence at amyotrophic lateral sclerosis diagnosis, with diabetes and obesity simultaneously included in the model. 2015 26030836
1700 Alzheimer's Disease Human Diabetes RF Diagnosis 2023 37563765
3414 Alzheimer's Disease Human Diabetes RF 1995 7473847
1447 Alzheimer's Disease Human Diabetes RF people with mild cognitive impairment (MCI) 2011 21518614
510 Alzheimer's Disease Human Diabetes PF with APOE4 genotype in AD population 2008 18189240
2245 Alzheimer's Disease Human Diabetes RF 2017 28503814
1702 Parkinson disease Human Diabetes RF Diagnosis infection with hepatitis C virus (HCV) 2023 36872452
2344 Parkinson disease Human Diabetes RF 2007 17251276
611 Amyotrophic Lateral Sclerosis Human Diabetes PF Diagnosis 2023 35983834
1497 Alzheimer's Disease Human Diabetes RF after Hemodialysis Initiation 2018 30093374
1633 Alzheimer's Disease Human Diabetes RF 2017 28806610
3035 Parkinson disease Human Diabetes RF 2009 19467671
3894 Alzheimer's Disease Human Diabetes RF Diagnosis 2023 35128745
1383 Alzheimer's Disease Human Diabetes RF 2021 33435977
2024 Parkinson disease Human Diabetes RF Diagnosis 2023 36342675
2719 Alzheimer's Disease Human Diabetes RF 2020 33126696
3413 Alzheimer's Disease Human Diabetes RF 2018 30149459
2993 Frontotemporal Dementia Human Diabetes RF 2014 24995127
1406 Alzheimer's Disease Human Diabetes RF Diagnosis 2022 35532912
577 Alzheimer's Disease Human Disorders in a 1st-degree relative PF Thyroid disorders 1990 2146525
2945 Alzheimer's Disease Human Disorders in a 1st-degree relative RF Probable AD 1990 2146525
2431 Alzheimer's Disease Human Disorders in a 1st-degree relative RF Down’s syndrome 1990 2146525
2871 Alzheimer's Disease Human Disorders in a 1st-degree relative RF Dementia 1990 2146525
3419 Alzheimer's Disease Human disseminated mycoses RF 2014 24452965
1846 Parkinson disease Human Drug-induced parkinsonism RF 1998 9703296
1845 Parkinson disease Human Drug-induced parkinsonism RF 1998 9703296
3447 Amyotrophic Lateral Sclerosis Human Fungal infection RF 2015 25892962
1604 Alzheimer's Disease Human heart disease RF 2020 32767997
564 Frontotemporal Lobar Degeneration Human heart disease PF 2012 22465176
3961 Parkinson disease Human heart disease RF Diagnosis 2022 34758470
3744 Alzheimer's Disease Human heart disease RF 2021 33527694
567 Frontotemporal Dementia Human heart disease PF 2012 22465176
1998 Parkinson disease Human Hepatitis C virus(HCV) RF 2016 26701382
2060 Parkinson disease Human Hepatitis C virus(HCV) RF 2015 25608223
1922 Parkinson disease Human Hepatitis C virus(HCV) RF 2019 30710864
3008 Alzheimer's Disease Human High blood pressure RF Diagnosis 2022 35587456
2037 Parkinson disease Human High blood pressure RF Diagnosis 2021 32876524
3454 Alzheimer's Disease Human High blood pressure RF intrinsic epigenetic age acceleration 2018 30167451
2497 Alzheimer's Disease Human history of depressive episodes RF 2008 18446027
423 Alzheimer's Disease Human history of hypercholesterolemia PF 2021 33967045
3461 Tuberous sclerosis complex Human history of infantile spasm (epileptic spasms) RF 2017 28721058
1456 Alzheimer's Disease Human Hospital-treated infectious diseases RF 2021 34166620
1945 Parkinson disease Human infection RF 2019 30632012
2674 Alzheimer's Disease Human infection RF Diagnosis 2022 36107840
1874 Parkinson disease Human infection RF Diagnosis 2022 36107840
1918 Alzheimer's Disease Human infection RF Diagnosis 2022 36107840
2075 Parkinson disease Human infection RF Diagnosis 2022 36107840
2619 Alzheimer's Disease Human infectious burden:C. pneumoniae RF 2015 24910016
2587 Alzheimer's Disease Human infectious burden:cytomegalovirus (CMV) RF 2015 24910016
1877 Alzheimer's Disease Human infectious disease burden RF 2021 33780369
2830 Alzheimer's Disease Human inflammatory bowel disease (IBD) RF Diagnosis 2023 35470286
1455 Alzheimer's Disease Human inflammatory bowel disease (IBD) RF 2021 34499125
1464 Parkinson disease Human inflammatory bowel disease (IBD) RF 2021 34499125
2578 Alzheimer's Disease Human inflammatory bowel disease (IBD) RF Diagnosis 2023 35470286
1889 Alzheimer's Disease Human inflammatory bowel disease (IBD) RF Diagnosis 2023 35470286
2784 Alzheimer's Disease Human Malaria RF 1990 2146525
3477 Alzheimer's Disease mice maternal transmission RF Tg2576 female mice 2018 29691440
3479 Parkinson disease Human motor neuron disease (MND) RF 2010 20669307
3676 Alzheimer's Disease Human Multiple vascular risk factors (VRFs) RF especially in APOE ε4 carriers 2020 31587263
1380 Alzheimer's Disease Human myocardial infraction (MI) RF 2021 33742562
488 Alzheimer's Disease Human Neoplasms PF 2021 33718584
494 Amyotrophic Lateral Sclerosis Human Neurological PF 2016 27065942
3728 Alzheimer's Disease mice Nonalcoholic fatty liver disease (NAFLD) RF 2021 33681678
1678 Alzheimer's Disease Human nonstroke cardiovascular disease (CVD) RF in carriers of the ApoE4 allele 2010 20473139
1597 Alzheimer's Disease Human normal tension glaucoma (NTG) RF Among patients with NTG, none of the glaucoma eye drops used significantly changed the risk of subsequent AD. 2018 30397009
450 Alzheimer's Disease Human Peripheral vascular disease PF after Hemodialysis Initiation 2018 30093374
3491 Alzheimer's Disease Human phosphatidylinositol clathrin assembly lymphoid-myeloid leukemia (PICALM) RF 2013 24067654
1614 Dementia with Lewy bodies Human positive family history of dementia or PD RF 2020 31771063
1650 Parkinson disease Human Prior stroke RF 2019 31019987
3529 Parkinson disease Human type 1 Gaucher disease RF 2010 20177787
3531 Alzheimer's Disease Human vascular risk RF 2010 20164563
3821 Multiple System Atrophy Human vascular risk factors RF Diagnosis 2021 34764851
3532 Alzheimer's Disease Human vascular risk factors(hypertension, diabetes, cerebrovascular diseases, and hypercholesterolemia) RF people with mild cognitive impairment (MCI) 2011 21490316
2664 Creutzfeldt-Jakob disease Human Zoster RF Zoster in adult life 1988 3066847
3013 Amyotrophic Lateral Sclerosis Human 20% continuous increase of any agricultural land or specific crop type RF Olive groves 2017 28851431
2041 Amyotrophic Lateral Sclerosis Human 20% continuous increase of any agricultural land or specific crop type RF Total agricultural land 2017 28851431
2141 Amyotrophic Lateral Sclerosis Human 20% continuous increase of any agricultural land or specific crop type RF Orchards 2017 28851431
3057 Alzheimer's Disease Human A priori occupations RF Printers, mechanics, garage workers, oilers, painters, auto body workers, wood finishers, shoemakers, and dry cleaners (as one of two longest held occupations). 1995 7771442
3546 Amyotrophic Lateral Sclerosis Human Aerosolization of cyanobacteria RF 2013 23246360
2175 Amyotrophic Lateral Sclerosis Human Agricultural chemicals (pesticides) RF 2018 29681882
1803 Amyotrophic Lateral Sclerosis Human Agricultural chemicals (pesticides) RF Diagnosis 2021 34137650
3380 Amyotrophic Lateral Sclerosis Human Agricultural chemicals (pesticides) RF 2010 20012543
3381 Amyotrophic Lateral Sclerosis Human agricultural work RF 2005 15995797
2120 Amyotrophic Lateral Sclerosis Human Air Force RF Adjusted for matching factors and socioeconomic status (SES) 2016 26583610
2292 Amyotrophic Lateral Sclerosis Human Air pollution RF Air Pollution Exposure(NO2) 2017 29989551
3701 Alzheimer's Disease Human Air pollution RF in Latin America and the Caribbean (LAC) 2021 34367051
1545 Alzheimer's Disease Human Air pollution RF Diagnosis 2023 36373950
1864 Alzheimer's Disease Human Air pollution RF Diagnosis 2023 36521347
3382 Alzheimer's Disease Human Air pollution RF 2019 30741678
3770 Alzheimer's Disease Human Air pollution RF Diagnosis cognitively unimpaired adults with increased risk of AD 2021 34537521
2048 Alzheimer's Disease Human Air pollution RF Diagnosis 2023 36521347
3703 Alzheimer's Disease Human Air pollution RF 2021 34258378
3723 Alzheimer's Disease Human Air pollution RF higher levels of CO, NO2, PM10, and SO2 exposure were associated with increased risk of AD cognitive deterioration;high SO2 exposure has the greatest impact while O3 has a neutral effect on AD cognitive deterioration 2021 33882496
1570 Alzheimer's Disease Human Air pollution RF 2021 33749652
3877 Parkinson disease Human Air pollution RF Diagnosis 2021 33476876
3691 AD,PD Human Air pollution RF 2021 34057650
3383 Amyotrophic Lateral Sclerosis Human Air pollution RF the nitrogen oxides NO2 and NOx 2018 29483062
2240 Amyotrophic Lateral Sclerosis Human Air pollution RF Air Pollution Exposure(PM2.5) 2017 29989551
2056 Amyotrophic Lateral Sclerosis Human Air pollution RF Air Pollution Exposure( NOx concentrations) 2017 29989551
3704 Alzheimer's Disease Human Air pollution RF 2021 34258378
1926 Alzheimer's Disease Human Air pollution RF Diagnosis 2023 36521347
1928 Amyotrophic Lateral Sclerosis Human an IQR increase of CO RF 2019 30622072
1901 Amyotrophic Lateral Sclerosis Human an IQR increase of PM10 RF 2019 30622072
1949 Amyotrophic Lateral Sclerosis Human an IQR increase of PM2.5 RF 2019 30622072
1927 Amyotrophic Lateral Sclerosis Human an IQR increase of SO2 RF 2019 30622072
1340 Amyotrophic Lateral Sclerosis Human Bank tellers RF worked or were unemployed at 1991 Italian census, and were still resident in Turin at the beginning of 1996 2017 28201634
2903 Alzheimer's Disease Human Benzene, toluene exposure RF 1995 7771442
3396 Parkinson disease Human chronic exposure to metals RF 1997 9065542
3397 Alzheimer's Disease mice Chronic low-dose-rate ionising radiation RF chronic low-dose-rate radiation exposure (1 mGy/day or 20 mGy/day) 2016 27708245
3766 Alzheimer's Disease mice chronic noise RF 2021 33407614
2741 Amyotrophic Lateral Sclerosis Human construction work RF 2016 27124833
2633 Amyotrophic Lateral Sclerosis Human construction work RF 2009 19750102
2364 Amyotrophic Lateral Sclerosis Human current proximity to any agricultural land or specific crop type within 100m from residence RF Total agricultural land 2017 28851431
2009 Amyotrophic Lateral Sclerosis Human Defense NEC(Not Elsewhere Classified) RF Adjusted for matching factors and socioeconomic status (SES) 2016 26583610
3036 Amyotrophic Lateral Sclerosis Human Distance agricultural areas RF 100m300m 2018 29852480
2714 Creutzfeldt-Jakob disease Human Duration (years) lived or worked on farm or market garden RF >=20 years 1999 10073510
2706 Creutzfeldt-Jakob disease Human Duration (years) lived or worked on farm or market garden RF 10-19 years 1999 10073510
801 Frontotemporal Lobar Degeneration Human duration of exposure PF for every 5 years of exposure increase 2017 28946566
1500 Alzheimer's Disease Human Employment status RF after Hemodialysis Initiation; Other 2018 30093374
422 Alzheimer's Disease Human Employment status PF after Hemodialysis Initiation; Employed 2018 30093374
1730 Alzheimer's Disease Human environmental exposure to cadmium RF high cadmium levels (>0.6 μg/L) 2016 27301955
2523 Amyotrophic Lateral Sclerosis Human environmental exposure to cadmium RF 2021 33068316
2483 Amyotrophic Lateral Sclerosis Human environmental exposure to cadmium RF 2021 33068316
2612 Amyotrophic Lateral Sclerosis Human environmental exposure to electromagnetic fields RF 2020 32331298
3427 Amyotrophic Lateral Sclerosis Human Environmental toxins RF organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs) and brominated flame retardants (BFRs) 2016 27231185
3429 Alzheimer's Disease mice excess zinc exposure RF 2010 21179415
2931 Frontotemporal Dementia Human exposure to Aluminum RF 2020 33138082
1347 Amyotrophic Lateral Sclerosis Human Exposure to extremely low frequency magnetic fields (ELF-MF) RF 2021 32946420
3431 Parkinson disease Human exposure to hydrocarbon solvents RF 2000 10980731
2361 Amyotrophic Lateral Sclerosis Human Exposure to Lead RF 2021 33068316
3432 Alzheimer's Disease Human Exposure to Lead RF Cigarette smoking 2017 29089568
2533 Amyotrophic Lateral Sclerosis Human Exposure to Lead RF 2021 33130429
2370 Amyotrophic Lateral Sclerosis Human Exposure to Lead RF 2009 19750102
2650 Amyotrophic Lateral Sclerosis Human Exposure to Lead RF residents of New England or the bordering New York region at the time of enrollment 2017 28122372
2709 Amyotrophic Lateral Sclerosis Human Exposure to Lead RF residents of New England or the bordering New York region at the time of enrollment 2017 28122372
2873 Amyotrophic Lateral Sclerosis Human Exposure to Lead RF 2020 32331298
2369 Amyotrophic Lateral Sclerosis Human Exposure to Lead RF Ever had a job with lead exposure 2005 16909025
2566 Amyotrophic Lateral Sclerosis Human Exposure to Lead RF Lifetime days of lead exposure:2,000+ 2005 16909025
2333 Amyotrophic Lateral Sclerosis Human Exposure to Lead RF 2021 33068316
3434 Parkinson disease Human exposure to metals RF high reported industrial release of copper or manganese 2010 20959505
3433 Parkinson disease Human exposure to metals RF high reported industrial release of copper or manganese 2010 20959505
2941 Amyotrophic Lateral Sclerosis Human exposure to metals RF particularly mercur yand selenium 2020 32331298
3435 Alzheimer's Disease Human Exposure to N2O RF 2019 29991368
3436 Parkinson disease Human Exposure to neuroleptic drugs RF 1999 10047927
2039 Progressive Supranuclear Palsy Human exposure to organic solvents RF self-reporting exposure to organic solvents 2016 26854325
2290 Parkinson disease Human exposure to Pb RF 2006 17185278
3437 Parkinson disease rat Exposure to Pesticide RF 2012 22563483
2821 Amyotrophic Lateral Sclerosis Human Exposure to Pesticide RF residents of New England or the bordering New York region at the time of enrollment 2017 28122372
2843 Amyotrophic Lateral Sclerosis Human Exposure to Pesticide RF residents of New England or the bordering New York region at the time of enrollment 2017 28122372
2863 Amyotrophic Lateral Sclerosis Human Exposure to Pesticide RF In a conditional logistic regression model 2010 20847462
2345 Parkinson disease Human Exposure to Pesticide RF 2001 11437458
2569 Parkinson disease Human Exposure to Pesticide RF 2020 32943485
2454 Parkinson disease Human Exposure to Pesticide RF 2010 21059511
1962 Amyotrophic Lateral Sclerosis Human Exposure to Pesticide RF Occupational but not environmental exposure,particularly fungicides 2020 32331298
2085 Progressive Supranuclear Palsy Human Exposure to Pesticide RF self-reporting exposure to pesticides 2016 26854325
3438 Alzheimer's Disease Human Exposure to PM2.5 RF 2018 29935448
2029 Amyotrophic Lateral Sclerosis Human Exposure to the highest quartiles of PM10 RF 2019 30622072
2070 Amyotrophic Lateral Sclerosis Human Exposure to the highest quartiles of PM2.5 RF 2019 30622072
3050 Parkinson disease Human exposure to trichloroethylene (TCE) RF 2012 22083847
3026 Amyotrophic Lateral Sclerosis Human Exposure to welding or soldering materials RF 2016 27124833
1348 Amyotrophic Lateral Sclerosis Human extremely low frequency magnetic fields (ELF-MF) RF Diagnosis 2021 32946420
3030 Multiple System Atrophy Human farming RF >20 years 2016 27670212
404 Alzheimer's Disease Human farming PF 2019 31239120
416 Alzheimer's Disease Human farming PF 2019 31239120
2078 Parkinson disease Human farming RF 2001 11437458
1796 Multiple System Atrophy Human farming RF >20 years 2016 27670212
2966 Multiple System Atrophy Human farming RF MSA cases vs. population controls;>20 years 2005 15382209
1825 Multiple System Atrophy Human farming RF MSA cases vs. population controls;>20 years 2005 15382209
2077 Amyotrophic Lateral Sclerosis Human farming RF 2021 33435977
2579 Multiple System Atrophy Human farming RF MSA cases vs. hospital controls 2005 15382209
2010 Parkinson disease Human farming RF 2021 33435977
2859 Multiple System Atrophy Human farming RF 1-20 years 2016 27670212
1804 Multiple System Atrophy Human farming RF MSA cases vs. hospital controls 2005 15382209
1821 Multiple System Atrophy Human farming RF MSA cases vs. population controls 2005 15382209
2852 Multiple System Atrophy Human farming RF MSA cases vs. population controls 2005 15382209
1826 Multiple System Atrophy Human farming RF 1-20 years 2016 27670212
3714 Alzheimer's Disease Human fine particulate matter (PM 2.5) RF 2021 34044832
2395 Amyotrophic Lateral Sclerosis Human Fire fighting occupations RF 2010 20698805
2401 Amyotrophic Lateral Sclerosis Human Fire fighting occupations RF 2010 20698805
794 Amyotrophic Lateral Sclerosis Human Formaldehyde (FA) PF Diagnosis 2021 33130429
3446 Alzheimer's Disease Human Formaldehyde (FA) RF 2014 24766729
1423 Creutzfeldt-Jakob disease Human Frequent exposure RF frequent exposure to leather products 1998 9660576
1431 Creutzfeldt-Jakob disease Human Frequent exposure RF exposure to fertiliser consisting of hoofs and horns 1998 9660576
1339 Amyotrophic Lateral Sclerosis Human General practitioners RF worked or were unemployed at 1991 Italian census, and were still resident in Turin at the beginning of 1996 2017 28201634
1453 Parkinson disease Human glyphosate exposure RF 2019 30799335
2092 Progressive Supranuclear Palsy Human have worked in transportation RF 2016 26854325
3957 Parkinson disease Human heavy metals RF Diagnosis 2022 34758470
3452 Amyotrophic Lateral Sclerosis Human heavy metals RF 1984 6538286
2276 Amyotrophic Lateral Sclerosis Human Heavy metals (lead) RF 2018 29681882
3453 Alzheimer's Disease Human Heavy metals toxicity:Cadmium (Cd) RF 2014 24557150
3542 Amyotrophic Lateral Sclerosis Human high amounts of PC(phycocyanin concentration) exposure RF 2018 28470570
849 Alzheimer's Disease Human High occupational attainment PF 2017 27662289
1636 Alzheimer's Disease Human High occupational attainment RF mild cognitive impairment(MCI) patient 2017 27662289
3459 Alzheimer's Disease Human higher levels of estrogen exposure RF 2014 24968011
3460 Alzheimer's Disease Human higher levels of prenatal testosterone exposure RF 2014 24968011
2500 Amyotrophic Lateral Sclerosis Human history of occupation in the agricultural sector RF 2020 32331298
2707 Amyotrophic Lateral Sclerosis Human history of occupation in the agricultural sector RF 2020 32331298
363 Alzheimer's Disease Human intellectual work PF people with mild cognitive impairment (MCI) 2011 21518614
3474 Alzheimer's Disease Human ionizing radiation RF 2017 28671130
2466 Alzheimer's Disease Human Job description only RF Exposure to printing/printer's ink, coal tar/creosote, oils, glues/resins/waxes, rubber production, or paints. 1995 7771442
2365 Alzheimer's Disease Human Job involves mainly walking or standing RF 2021 33718584
2891 Alzheimer's Disease Human Jobs as seamstress, dressmaker and tailor RF 1995 7677130
2781 Alzheimer's Disease Human Jobs as seamstress, dressmaker and tailor RF 1995 7677130
2643 Amyotrophic Lateral Sclerosis Human Jobs as workers or farmers RF 2019 31155341
3090 Alzheimer's Disease Human Ketones exposure RF 1995 7771442
3959 Parkinson disease Human living in an urban area RF Diagnosis 2022 34758470
886 Alzheimer's Disease Human living in an urban area PF 2021 34499125
3475 Amyotrophic Lateral Sclerosis Human Living in rural environment RF Region of living more than 5 years before disease onset 2019 31011473
3719 Alzheimer's Disease Human living in the most highly disadvantaged neighborhoods RF 2021 33853894
1984 Progressive Supranuclear Palsy Human living on a farm or ranch RF more years living on a farm or ranch 2016 26854325
2042 Alzheimer's Disease Human long-term exposures to ambient particulate matter 2.5 (PM2.5) RF in North Carolina (NC) 2021 34242242
1410 Alzheimer's Disease Human Low-frequency electromagnetic fields RF 2021 33435977
1995 Amyotrophic Lateral Sclerosis Human Low-frequency electromagnetic fields RF 2021 33435977
2655 Motor Neuron Disease Human manual occupation RF 1993 8229031
2984 Tourette Syndrome Human Maternal toxic exposures RF Cannabis use in last 2 months of pregnancy; Mutually adjusted for other variables in the model, maternal age and socioeconomic status level. 2014 24262815
2170 Tourette Syndrome Human Maternal toxic exposures RF Alcohol use in last 2 months of pregnancy; Mutually adjusted for other variables in the model, maternal age and socioeconomic status level. 2014 24262815
2266 Amyotrophic Lateral Sclerosis Human medical service work RF 2016 27124833
3478 Amyotrophic Lateral Sclerosis Human metals as Al, Cd, Hg, Mn and Pb RF 2015 26671079
3702 Alzheimer's Disease rat Methamphetamine (METH) RF 2021 34224806
1460 Amyotrophic Lateral Sclerosis Human Military work RF born between 1945 and 1985 2015 26468494
2008 Amyotrophic Lateral Sclerosis Human Military work RF Adjusted for matching factors and socioeconomic status (SES) 2016 26583610
1959 Progressive Supranuclear Palsy Human more years living within one mile of an agricultural area RF more years living within one mile of an agricultural area 2016 26854325
3787 Amyotrophic Lateral Sclerosis Human National Football League (NFL) Athletes RF Diagnosis, prognosis 2021 34910152
2909 Amyotrophic Lateral Sclerosis Human Occupation RF Primary occupation involves industrial chemicals;residents of New England or the bordering New York region at the time of enrollment 2017 28122372
634 Amyotrophic Lateral Sclerosis Human Occupation PF tertiary industrial occupations(at disease onset) 2007 17538776
2698 Amyotrophic Lateral Sclerosis Human Occupation RF primary industrial occupations(at disease onset) 2007 17538776
3098 Amyotrophic Lateral Sclerosis Human Occupation RF Craft and related trades workers(Crude OR) 2007 17923612
1337 Amyotrophic Lateral Sclerosis Human Occupation RF Occupations in contact with customer;sworked or were unemployed at 1991 Italian census, and were still resident in Turin at the beginning of 1996 2017 28201634
2725 Amyotrophic Lateral Sclerosis Human Occupation RF secondary industrial occupations(at disease onset) 2007 17538776
3104 Amyotrophic Lateral Sclerosis Human Occupation RF Primary occupation involves industrial chemicals;residents of New England or the bordering New York region at the time of enrollment 2017 28122372
2197 Motor Neuron Disease Human Occupation RF Work as farmers and breeders 1991 1745327
4126 Amyotrophic Lateral Sclerosis Human Occupational exposure RF Diagnosis 2019 30705111
4127 Amyotrophic Lateral Sclerosis Human Occupational exposure RF Diagnosis 2019 30649156
51 Alzheimer's Disease Human Occupational exposure Not Related Diagnosis 1996 8837919
287 Amyotrophic Lateral Sclerosis Human Occupational exposure Not Related Diagnosis 2015 26414853
2825 Motor Neuron Disease Human Occupational Exposure RF occupational exposure to solvents/chemicals 1993 8229031
1957 Amyotrophic Lateral Sclerosis Human Occupational Exposure RF Diagnosis 2022 35593931
3117 Creutzfeldt-Jakob disease Human Occupational Exposure RF occupational exposure to animal laboratory 2009 19144172
1074 Alzheimer's Disease Human Occupational exposure PF Diagnosis 2001 11416089
56 Alzheimer's Disease Human Occupational exposure Not Related Diagnosis 1997 9071441
3041 Motor Neuron Disease Human Occupational Exposure RF occupational exposure to lead 1993 8229031
4068 Alzheimer's Disease Human Occupational exposure RF Diagnosis 2013 22899726
61 Alzheimer's Disease Human Occupational exposure Not Related Diagnosis 1997 9071441
331 Multiple System Atrophy Human Occupational exposure Not Related Diagnosis 2008 18307243
1114 Amyotrophic Lateral Sclerosis Human Occupational exposure PF Prognosis 2015 24917188
284 Amyotrophic Lateral Sclerosis Human Occupational exposure Not Related Diagnosis 1991 1798425
4129 Amyotrophic Lateral Sclerosis Human Occupational exposure RF Prognosis 2015 25229273
53 Alzheimer's Disease Human Occupational exposure Not Related Diagnosis 1997 9071441
357 Progressive Supranuclear Palsy Human Occupational exposure Not Related Diagnosis 2009 19864660
289 Amyotrophic Lateral Sclerosis Human Occupational exposure Not Related Prognosis 2015 24917188
4065 Alzheimer's Disease Human Occupational exposure RF Diagnosis 1995 7771442
2011 Progressive Supranuclear Palsy Human Occupational Exposure RF occupational metal exposure 2016 26854325
58 Alzheimer's Disease Human Occupational exposure Not Related Diagnosis 1997 9071441
4288 Parkinson disease Human Occupational exposure RF Diagnosis 1992 1620342
63 Alzheimer's Disease Human Occupational exposure Not Related Diagnosis 1997 9071441
333 Multiple System Atrophy Human Occupational exposure Not Related Diagnosis 2008 18307243
4125 Amyotrophic Lateral Sclerosis Human Occupational exposure RF Diagnosis 2019 30705111
286 Amyotrophic Lateral Sclerosis Human Occupational exposure Not Related Diagnosis 2015 26414853
4175 Creutzfeldt-Jakob disease Human Occupational exposure RF Diagnosis 1998 9660576
55 Alzheimer's Disease Human Occupational exposure Not Related Diagnosis 1997 9071441
4067 Alzheimer's Disease Human Occupational exposure RF Diagnosis 2013 22899726
4136 Amyotrophic Lateral Sclerosis Human Occupational exposure RF Diagnosis 2018 29685899
60 Alzheimer's Disease Human Occupational exposure Not Related Diagnosis 1997 9071441
65 Alzheimer's Disease Human Occupational exposure Not Related Diagnosis 1997 9071441
2088 Amyotrophic Lateral Sclerosis Human Occupational Exposure RF Diagnosis 2022 35593931
4122 Amyotrophic Lateral Sclerosis Human Occupational exposure RF Diagnosis 2005 16909025
283 Amyotrophic Lateral Sclerosis Human Occupational exposure Not Related Diagnosis 1991 1798425
4128 Amyotrophic Lateral Sclerosis Human Occupational exposure RF Diagnosis 2019 30649156
52 Alzheimer's Disease Human Occupational exposure Not Related Diagnosis 1997 9071441
356 Progressive Supranuclear Palsy Human Occupational exposure Not Related Diagnosis 2009 19864660
288 Amyotrophic Lateral Sclerosis Human Occupational exposure Not Related Prognosis 2015 24917188
4133 Amyotrophic Lateral Sclerosis Human Occupational exposure RF Diagnosis 2014 24246552
57 Alzheimer's Disease Human Occupational exposure Not Related Diagnosis 1997 9071441
4069 Alzheimer's Disease Human Occupational exposure RF Diagnosis 2013 22899726
62 Alzheimer's Disease Human Occupational exposure Not Related Diagnosis 1997 9071441
332 Multiple System Atrophy Human Occupational exposure Not Related Diagnosis 2008 18307243
1115 Amyotrophic Lateral Sclerosis Human Occupational exposure PF Prognosis 2015 24917188
1944 Amyotrophic Lateral Sclerosis Human Occupational Exposure RF Diagnosis 2022 35593931
4124 Amyotrophic Lateral Sclerosis Human Occupational exposure RF Diagnosis 1986 3962963
285 Amyotrophic Lateral Sclerosis Human Occupational exposure Not Related Diagnosis 1991 1798425
2102 Amyotrophic Lateral Sclerosis Human Occupational Exposure RF Diagnosis 2022 35593931
4174 Creutzfeldt-Jakob disease Human Occupational exposure RF Diagnosis 1998 9660576
54 Alzheimer's Disease Human Occupational exposure Not Related Diagnosis 1997 9071441
358 Progressive Supranuclear Palsy Human Occupational exposure Not Related Diagnosis 2009 19864660
4066 Alzheimer's Disease Human Occupational exposure RF Diagnosis 1995 7771442
59 Alzheimer's Disease Human Occupational exposure Not Related Diagnosis 1997 9071441
4289 Parkinson disease Human Occupational exposure RF Diagnosis 1989 2710356
64 Alzheimer's Disease Human Occupational exposure Not Related Diagnosis 1997 9071441
4121 Amyotrophic Lateral Sclerosis Human Occupational exposure RF Diagnosis 2005 16909025
3074 Amyotrophic Lateral Sclerosis Human Occupational Exposure RF Occupational exposure to pesticide;Exposure in the last 30 years 2014 24979055
2258 Amyotrophic Lateral Sclerosis Human occupational exposure to electromagnetic fields RF 2020 32331298
2476 Amyotrophic Lateral Sclerosis Human occupational exposure to Solvents(paint removers) RF 2020 32331298
2560 Amyotrophic Lateral Sclerosis Human occupational exposure to Solvents(thinners) RF 2020 32331298
2785 Amyotrophic Lateral Sclerosis Human Occupational history RF Occupational history:Building and construction sector of economic activity;Spinal cases 2009 19922125
3024 Amyotrophic Lateral Sclerosis Human Occupational history RF Occupational history:Exposure to building and construction materials;Spinal cases 2009 19922125
2757 Amyotrophic Lateral Sclerosis Human Occupational history RF Occupational history:Exposure to metals and metal fumes;Spinal cases 2009 19922125
1799 Amyotrophic Lateral Sclerosis Human Occupational history RF Diagnosis 2022 35084274
3975 Amyotrophic Lateral Sclerosis Human Occupational history RF Diagnosis 2023 37166887
1790 Amyotrophic Lateral Sclerosis Human Occupational history RF Diagnosis 2022 35084274
2406 Amyotrophic Lateral Sclerosis Human occupational work intensity RF Diagnosis German 2021 34670816
2316 Amyotrophic Lateral Sclerosis Human office work RF 2016 27124833
3485 Parkinson disease Human organophosphate (OP) or carbamate (CM) poisoning RF 2017 27781262
2947 Alzheimer's Disease Human Other solvents exposure RF 1995 7771442
2708 Frontotemporal Dementia Human Overall solvents and dyes RF 2020 33138082
2044 Parkinson disease Human paraquat exposure RF 2012 23150532
3487 Amyotrophic Lateral Sclerosis Human particulate matter RF PM2.5, PM10, and PMcoarse 2018 29483062
3488 Amyotrophic Lateral Sclerosis Human particulate matter absorption RF PM2.5absorption 2018 29483062
2999 Alzheimer's Disease Human Phenols, alcohols exposure RF 1995 7771442
3687 Creutzfeldt-Jakob disease Human Physicians RF 2020 32687038
3493 Parkinson disease Human Polychlorinated biphenyls (PCBs)exposure RF greater susceptibility of females. 2012 22906799
3982 Amyotrophic Lateral Sclerosis Human Polychlorinated biphenyls (PCBs)exposure RF Diagnosis 2022 35041949
3494 Parkinson disease Human Polychlorinated biphenyls (PCBs)exposure RF greater susceptibility of females. 2012 22906799
2543 Amyotrophic Lateral Sclerosis Human precision metal workers RF 2009 19750102
3496 Alzheimer's Disease Human prenatal estrogen exposure RF lower levels of prenatal estrogen exposure 2014 24968011
3497 Alzheimer's Disease Human prenatal testosterone exposure RF lower levels of prenatal testosterone exposure 2014 24968011
2660 Alzheimer's Disease Human Probable solvent exposure RF Any above-named solvent or job description. 1995 7771442
2468 Alzheimer's Disease Human Probable solvent exposure RF Any above-named solvent or job description. 1995 7771442
2653 Creutzfeldt-Jakob disease Human Residence or employment RF Live or employed in farms 1999 10073510
872 Alzheimer's Disease Human Residential exposure to green spaces PF 2021 34258378
1654 Alzheimer's Disease Human Rural residency RF 2015 25401488
1338 Amyotrophic Lateral Sclerosis Human Sales representatives RF worked or were unemployed at 1991 Italian census, and were still resident in Turin at the beginning of 1996 2017 28201634
2780 Tuberous sclerosis complex Human Seizure type (ie, infantile spasms) RF 1998 9520012
3503 Amyotrophic Lateral Sclerosis Human selenium overexposure RF 2011 21215776
1867 Amyotrophic Lateral Sclerosis Human Solvent exposure RF 2021 33130429
2110 Amyotrophic Lateral Sclerosis Human Solvent exposure RF Diagnosis 2021 33130429
2482 Amyotrophic Lateral Sclerosis Human Solvent exposure RF residents of New England or the bordering New York region at the time of enrollment 2017 28122372
3072 Alzheimer's Disease Human Solvent exposure RF Any positive response to a named solvent group. 1995 7771442
1866 Amyotrophic Lateral Sclerosis Human Solvent exposure RF Diagnosis 2021 33130429
2109 Amyotrophic Lateral Sclerosis Human Solvent exposure RF 2021 33130429
2701 Alzheimer's Disease Human Solvent exposure RF Any positive response to a named solvent group 1995 7771442
2382 Motor Neuron Disease Human Solvent exposure RF Diagnosis 2022 35318275
3516 Amyotrophic Lateral Sclerosis Human spatial locations RF 2008 18573277
3523 Amyotrophic Lateral Sclerosis Human The widespread distribution of dioxins, PCBs and PAHs RF 2017 28476168
2726 Amyotrophic Lateral Sclerosis Human Toxin exposure RF 2006 16963407
3084 Parkinson disease Human Toxins other than pesticide RF 2010 21059511
3747 Alzheimer's Disease mice traffic noise RF 2021 33096582
3528 Parkinson disease Human Trichloroethylene RF 2008 18157908
1558 Alzheimer's Disease Human urbanization status RF 2014 24489845
2637 Amyotrophic Lateral Sclerosis Human Use of chemicals in job or hobby RF residents of New England or the bordering New York region at the time of enrollment 2017 28122372
2354 Amyotrophic Lateral Sclerosis Human Use of chemicals in job or hobby RF residents of New England or the bordering New York region at the time of enrollment 2017 28122372
2542 Progressive Supranuclear Palsy Human Use of firearm in service RF 2018 29973911
2393 Amyotrophic Lateral Sclerosis Human use of herbicides during gardening RF 2020 32019087
2762 Amyotrophic Lateral Sclerosis Human Using fertilizer to treat gardens RF Exposure in the period from 30 years ago to 10 years ago 2014 24979055
3536 Parkinson disease Human welding RF 2001 11148228
2432 Alzheimer's Disease Human β- hexachlorocyclohexane RF 2012 22904031
1446 Tuberous sclerosis complex Human administration of multiple antiepileptic drugs RF 2009 20113608
761 Amyotrophic Lateral Sclerosis Human antidiabetics PF 2020 32097525
551 Parkinson disease Human anti-histamines PF 2021 34494887
1776 Alzheimer's Disease Human benzodiazepine and related drug (BZDR) RF 2018 29851063
2474 Progressive Supranuclear Palsy Human beta-blocker use RF 2019 31420308
3399 Parkinson disease rat cinnarizine(a calcium antagonist that produces human parkinsonism) RF (a calcium antagonist that produces human parkinsonism) 2005 15993444
435 Parkinson disease Human deep brain stimulation (DBS) treatment PF Prognosis 2021 33278869
870 Alzheimer's Disease mice dexibuprofen (DXI) PF 2021 34294142
397 Parkinson disease Human Dipeptidyl peptidase-4 (DPP4) inhibitors PF Diagnosis in diabetic patients 2023 38110464
401 Parkinson disease Human Dipeptidyl peptidase-4 (DPP4) inhibitors PF Treatment 2021 33895825
1884 Parkinson disease Human duration of exposure to levodopa RF 2013 23836370
1885 Parkinson disease Human duration of exposure to levodopa RF 2013 23836370
819 Amyotrophic Lateral Sclerosis Human Duration of OCP(oral contraceptive) use (per year) PF female 2017 28835399
519 Alzheimer's Disease Human Estrogen-replacement therapy PF postmenopausal women 1998 9566385
3102 Frontotemporal Dementia Human Excluding specific neuroprotective supplements RF after onset of disease 2020 33138082
3053 Parkinson disease Human general anesthesia RF 2020 32943485
2886 Amyotrophic Lateral Sclerosis Human having a past history of CS/SSM RF 2007 17538776
2952 Amyotrophic Lateral Sclerosis Human having surgical treatment for CS/SSM RF 2007 17538776
432 Alzheimer's Disease Human Hearing aid PF hearing-impaired adults 2021 33614893
1802 Multiple System Atrophy Human Herbal medications RF 2010 20623770
2611 Multiple System Atrophy Human Herbal medications RF 2010 20623770
1637 Creutzfeldt-Jakob disease Human hGH(human cadaver-sourced growth hormone) treatment RF 2018 30045957
1766 Creutzfeldt-Jakob disease Human hGH(human cadaver-sourced growth hormone) treatment RF Proportion of doses risk category 1 (batches 1, 2, 3, 4, 7, 21, 26) 2018 30045957
1758 Creutzfeldt-Jakob disease Human hGH(human cadaver-sourced growth hormone) treatment RF Proportion of doses risk category 3 (batches 5, 6, 8, 9, 11, 14, 15, 16, 17, 19, 20, 22, 23, 25, 27) 2018 30045957
1728 Creutzfeldt-Jakob disease Human hGH(human cadaver-sourced growth hormone) treatment RF Proportion of doses risk category 2 (batches 10, 12, 13, 18, 24) 2018 30045957
3462 Creutzfeldt-Jakob disease Human human growth hormone extract RF received human growth hormone extract for various period of time (mean +/- SD, 2.9 years) 1996 8797466
514 Amyotrophic Lateral Sclerosis Human Immunosuppressive drugs PF 2014 25059395
2733 Alzheimer's Disease Human inappropriate use anti-dementia drugs RF 2020 32251456
3471 Amyotrophic Lateral Sclerosis Human inhalation of BMAA, DAB, and other aerosolized cyanotoxins RF 2009 19929742
2155 Alzheimer's Disease Human irregular medication use anti-dementia drugs RF 2020 32251456
2423 Tourette Syndrome Human longer delay of treatment RF 2010 20654033
1882 Parkinson disease Human metoprolol RF 2021 34598055
3889 Tuberous sclerosis complex Human multiple antiepileptic drugs RF Diagnosis 2021 33225634
566 Alzheimer's Disease Human no chronic use of nonsteroidal anti-inflammatory drugs PF 2008 18446027
373 Parkinson disease Human Non-aspirin NSAIDS PF 2021 33435977
392 Alzheimer's Disease Human Non-aspirin NSAIDS PF 2021 33435977
400 Parkinson disease Human non-hydroxychloroquine immunosuppressant therapy PF Sj?gren syndrome (SS) 2019 30946325
2464 Creutzfeldt-Jakob disease Human Number of surgical procedures RF 2 times 2002 12196646
2185 Creutzfeldt-Jakob disease Human Number of surgical procedures RF >=3 times 2002 12196646
2314 Creutzfeldt-Jakob disease Human Number of surgical procedures RF 1 time 2002 12196646
2930 Amyotrophic Lateral Sclerosis Human OCP(oral contraceptive) RF Prognosis postmenopausal 2023 37493444
702 Amyotrophic Lateral Sclerosis Human OCP(oral contraceptive) PF female 2017 28835399
2456 Tuberous sclerosis complex Human poor control of subsequent seizures after IS RF 2005 16043792
1777 Parkinson disease Human Proton pump inhibitors (PPIs) RF Diagnosis 1-year lag period was applied between PPI exposure and PD development 2023 38096177
3499 Alzheimer's Disease Human Proton pump inhibitors (PPIs) RF Chronic consumption of PPIs 2010 20456731
2576 Creutzfeldt-Jakob disease Human regular medication RF 2009 19144172
469 Alzheimer's Disease Human Statin therapy PF 2020 32753051
817 Alzheimer's Disease Human statin use PF 2021 33804752
897 Parkinson disease Human statin use PF 2021 34275907
398 Alzheimer's Disease Human statin use PF 2010 20533968
2478 Parkinson disease Human statin use RF 2021 34347020
1580 Alzheimer's Disease Human Underwent Surgery under Neuraxial Anesthesia RF Diagnosis 2021 34945858
645 Multiple System Atrophy Human use of non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) PF Cumulative doses were used to divide observations into tertiles creating 3 groups of equal size (T1–3) based on the consumption in DDDs with T1 representing the group with the lowest use and T3 the highest. 2020 31661696
735 Multiple System Atrophy Human use of non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) PF 2020 31661696
766 Multiple System Atrophy Human use of non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) PF Cumulative doses were used to divide observations into tertiles creating 3 groups of equal size (T1–3) based on the consumption in defined daily dose(DDD) with T1 representing the group with the lowest use and T3 the highest. 2020 31661696
1993 Amyotrophic Lateral Sclerosis Human Use of statins RF 2020 32097525
583 Amyotrophic Lateral Sclerosis Human Use of statins PF 2014 25059395
803 Parkinson disease Human β-agonists PF 2021 34598055
1940 Parkinson disease Human β-antagonists RF 2021 34598055
3898 Alzheimer's Disease Human gut microbiota RF Diagnosis 2023 37002253
3948 Parkinson disease Human gut microbiota RF Diagnosis 2022 35275534
4377 Amyotrophic Lateral Sclerosis Human gut microbiota RF/PF butyrate-producing bacteria are less abundant in the gastrointestinal tracts of people with ALS (PALS) 2021 33135936
3900 Alzheimer's Disease mice gut microbiota RF Diagnosis 2023 35619714
1969 Amyotrophic Lateral Sclerosis Human gut microbiota RF Diagnosis 2022 35275534
3947 Alzheimer's Disease Human gut microbiota RF Diagnosis 2022 35275534
3837 Parkinson disease Human gut microbiota RF Prognosis 2021 34954497
3949 Amyotrophic Lateral Sclerosis Human gut microbiota RF Diagnosis 2022 35275534
505 Amyotrophic Lateral Sclerosis Human gut microbiota PF Diagnosis Butyrate producing-species are lower in people with ALS 2021 33135936
1651 Alzheimer's Disease Human higher CDR-SB scores RF in male 2015 26343475
850 Alzheimer's Disease Human Maternal breastfeeding history PF Women who breastfed had lower AD risk than women who did not breastfeed(p = 0.017) 2013 23948914
1445 Parkinson disease Human MDS-UPDRS motor complications score RF Diagnosis 2021 33505652
3613 Alzheimer's Disease Human menopause transition (MT) RF decreased metabolic activity and increased brain amyloid-beta deposition 2018 30298180
2282 Amyotrophic Lateral Sclerosis Human predominant upper motor neuron (PUMN) phenotype RF Diagnosis 2021 33563800
1662 Parkinson disease Human Suicide RF Prognosis 2021 33326004
464 Alzheimer's Disease Human 25(OH)D deficiency PF 2017 28522216
3373 Alzheimer's Disease Human a decrease in LRP10 function RF 2012 22734645
2407 Alzheimer's Disease Human abnormal serum Hcy elevation RF 2021 33907404
3816 Lewy Body Disease Human abnormalities in ceramide metabolism RF 2021 34514546
1625 Alzheimer's Disease Human Albuminuria RF Model 3:adjusted for Model 2 plus eGFR 2018 29353232
1619 Alzheimer's Disease Human Albuminuria RF Model 1:adjusted for age and sex 2018 29353232
1593 Alzheimer's Disease Human Albuminuria RF Model 1:adjusted for age and sex 2018 29353232
1607 Alzheimer's Disease Human Albuminuria RF Model 3:adjusted for Model 2 plus eGFR 2018 29353232
1624 Alzheimer's Disease Human Albuminuria RF Model 2:adjusted for Model 1 plus educational level, history of stroke, systolic blood pressure, the use of antihypertensive agents, diabetes mellitus, total cholesterol, body mass index, smoking habits, alcohol intake, and regular exercise 2018 29353232
1609 Alzheimer's Disease Human Albuminuria RF Model 2:adjusted for Model 1 plus educational level, history of stroke, systolic blood pressure, the use of antihypertensive agents, diabetes mellitus, total cholesterol, body mass index, smoking habits, alcohol intake, and regular exercise 2018 29353232
776 Alzheimer's Disease Human Basal metabolic rate PF 2021 33718584
3560 Alzheimer's Disease Human Blood levels of alpha-1-antichymotrypsin(ACT) RF 2018 10629358
731 Alzheimer's Disease Human blood levels of Selenium (μg/dL) PF Diagnosis 2022 35742553
2602 Alzheimer's Disease Human blood levels of chromium RF Diagnosis 2022 35742553
3693 Alzheimer's Disease Human blood lipid levels RF 2021 34340865
1481 Alzheimer's Disease Human bone mineral density (BMD) RF low bone mineral density (BMD) 2011 21187587
511 Parkinson disease Human Bone mineral density in femoral neck PF 2021 33435977
644 Parkinson disease Human Bone mineral density in hip PF 2021 33435977
526 Parkinson disease Human Bone mineral density in lumbar spine PF 2021 33435977
2995 Tuberous sclerosis complex Human calcification in the cerebral parenchyma RF 2018 29929111
873 Alzheimer's Disease Human Cardiorespiratory fitness (CRF) PF 2021 34268447
843 Alzheimer's Disease Human Cardiorespiratory fitness (CRF) PF 2017 28293467
456 Alzheimer's Disease Human Cardiorespiratory fitness (CRF) PF Diagnosis 2023 36946469
420 Alzheimer's Disease Human Cardiorespiratory fitness (CRF) PF Diagnosis 2023 36946469
441 Alzheimer's Disease Human Cardiorespiratory fitness (CRF) PF Diagnosis 2023 36946469
433 Alzheimer's Disease Human Cardiorespiratory fitness (CRF) PF Diagnosis 2023 36946469
436 Alzheimer's Disease Human carotid distensibility PF 2021 33870735
1541 Alzheimer's Disease Human carotid intima-media thickness RF 2021 33870735
3755 Alzheimer's Disease Human cholesterol levels RF 2021 32996171
1973 Alzheimer's Disease Human decreased 25-hydroxyvitamin D(25OHD) level RF 2017 27856775
2539 Frontotemporal Lobar Degeneration Human Delayed, prolonged Orthostatic hypotension (OH) RF compared to subjects without OH in subjects with MCI and patients with dementia 2019 31381517
2541 Frontotemporal Lobar Degeneration Human Delayed, prolonged Orthostatic hypotension (OH) RF compared to subjects without OH in subjects with MCI and patients with dementia 2019 31381517
2540 Frontotemporal Lobar Degeneration Human Delayed, prolonged Orthostatic hypotension (OH) RF compared to subjects without OH in subjects with MCI and patients with dementia 2019 31381517
1513 Alzheimer's Disease Human diastolic blood pressure [DBP] RF 2020 32979926
884 Alzheimer's Disease Human diastolic blood pressure [DBP] PF 2021 32996171
818 Amyotrophic Lateral Sclerosis Human diastolic blood pressure [DBP] PF Diagnosis 2022 35172853
525 Parkinson disease Human dyslipidemia PF Prognosis 2021 33219665
1703 Alzheimer's Disease Human dyslipidemia RF 2020 32485802
1528 Parkinson disease Human dyslipidemia RF Diagnosis 2023 36692249
2556 Alzheimer's Disease Human dyslipidemia RF 2019 30894904
1773 Alzheimer's Disease Human dyslipidemia RF (a higher LDL cholesterol level) 2020 32753051
3579 Alzheimer's Disease Human Elevated blood plasma levels of α7(1-208) nAChR-specific antibodies RF 2011 21593571
3580 Alzheimer's Disease Human Elevated Low-density Lipoprotein Cholesterol Levels(LDL-C) RF 2019 31135820
3581 Alzheimer's Disease Human elevated malondialdehyde levels RF The elevated malondialdehyde levels increases the risk of Alzheimer's disease by 9.342. 2016 26835020
2720 Alzheimer's Disease Human elevated midlife total cholesterol level RF 2002 12160362
3867 Parkinson disease Human elevated plasma Aβ40 levels RF Diagnosis 2021 33782518
1563 Alzheimer's Disease Human fasting plasma glucose (FPG) RF Model III: adjusted for CAD, CHF, stroke, cancer, hyperlipidemia, hypertension, atrial fibrillation, chronic hepatitis, COPD, and hypoglycemia along with all other confounders in model II 2017 28705834
1544 Alzheimer's Disease Human fasting plasma glucose (FPG) RF Model IV: adjusted for PFG CV and HbA1c CV along with all other confounders in model III 2017 28705834
1569 Alzheimer's Disease Human fasting plasma glucose (FPG) RF Model II: adjusted for age, sex, FPG,HbA1c, insured amount and insured unit (see Table 1), smoking, alcohol consumption, duration of diabetes, type of hypoglycemic drug, hypertension drug treatment, and obesity 2017 28705834
2004 Alzheimer's Disease Human fasting plasma glucose (FPG) RF 2020 33177243
1613 Alzheimer's Disease Human fasting plasma glucose (FPG) RF Model I: adjusted for age and sex 2017 28705834
1567 Parkinson disease Human fasting plasma glucose (FPG) variability RF Diagnosis in the midlife population without diabetes 2021 33039669
2872 Dementia with Lewy bodies Human Having three metabolic risk factors RF 2018 29971140
2744 Alzheimer's Disease Human head circumference (HC) RF within the lowest quintile of HC for women 1997 9222166
1939 Parkinson disease Human high fasting blood glucose RF Diagnosis 2021 32876524
3586 Amyotrophic Lateral Sclerosis Human high HbA1c(Hemoglobin A1c) levels RF 2017 28934974
3587 Alzheimer's Disease Human high level of Dkk1 RF 2016 26880631
860 Progressive Supranuclear Palsy Human high levels of uric acid PF 2016 26686202
2659 Alzheimer's Disease Human high midlife systolic blood pressure RF 2002 12160362
3588 Alzheimer's Disease Human high plasma clusterin levels RF 2015 26402636
3589 Parkinson disease Human high serum lipid peroxidation rates RF 1992 1641180
816 Alzheimer's Disease Human High thiamine diphosphate level PF 2018 29718773
707 Parkinson disease Human High triglycerides PF Diagnosis 2021 32876524
1413 Amyotrophic Lateral Sclerosis Human high-density lipoprotein cholesterol (HDL-C) RF Diagnosis 2021 32985910
3988 Lewy Body Disease Human high-density lipoprotein cholesterol (HDL-C) RF Diagnosis 2022 35124646
924 Parkinson disease Human high-density lipoprotein cholesterol (HDL-C) PF Diagnosis 2022 35723114
720 Alzheimer's Disease Human high-density lipoprotein cholesterol (HDL-C) PF 2020 33177243
3674 Alzheimer's Disease Human high-density lipoprotein cholesterol (HDL-C) RF 2020 32979926
3715 Alzheimer's Disease Human Higher homocysteine level RF 2021 34057086
399 Alzheimer's Disease Human Higher leptin level PF 2011 21187587
1341 Alzheimer's Disease Human homocysteine (Hcy) RF elevated plasma Hcy levels 2021 34122042
810 Alzheimer's Disease Human Improving cardiovascular functions PF mean velocity of the LTICA 2017 28505975
784 Alzheimer's Disease Human Improving cardiovascular functions PF mean velocity of the BA 2017 28505975
757 Alzheimer's Disease Human Improving cardiovascular functions PF Ejection fraction 2017 28505975
3591 Alzheimer's Disease Human increased cholesterol or blood pressure RF 2018 30112972
3594 Alzheimer's Disease Human Increased levels of specific sub-fractions of LDL cholesterol RF 2007 17982892
1490 Alzheimer's Disease Human increased plasma adiponectin levels RF 2012 22213409
3595 Alzheimer's Disease Human increased platelet membrane fluidity RF first-degree relatives of probands with Alzheimer's disease 1996 8610834
862 Alzheimer's Disease Human increased skeletal muscle mass PF 2019 30700801
1537 Alzheimer's Disease Human interadventitial diameter RF 2021 33870735
1712 Alzheimer's Disease Human Leukocyte telomere length (LTL) RF short rLTL 2021 34266503
3131 Alzheimer's Disease Human Leukocyte telomere length (LTL) RF shorter telomere length 2021 33679878
789 Amyotrophic Lateral Sclerosis Human Leukocyte telomere length (LTL) PF Diagnosis driven by rs940209 in the OBFC1 gene 2021 34906191
3600 Alzheimer's Disease Human levels of homocysteine RF 2010 20885792
900 Parkinson disease Human levels of total cholesterol, triglyceride, and uric acid PF Diagnosis 2021 33905014
2503 Amyotrophic Lateral Sclerosis Human lifetime endogenous estrogen (LEE) RF Prognosis postmenopausal 2023 37493444
408 Amyotrophic Lateral Sclerosis Human lifetime endogenous estrogen (LEE) PF Prognosis postmenopausal 2023 37493444
1872 Amyotrophic Lateral Sclerosis Human lifetime endogenous estrogen (LEE) RF 2017 28835399
3602 Alzheimer's Disease Human Longitudinal Changes in Serum Glucose Levels RF 2018 29480176
2017 Parkinson disease Human low high-density lipoprotein cholesterol RF Diagnosis 2021 32876524
658 Frontotemporal Lobar Degeneration Human Low levels of serum uric acid (UA) PF 2017 28620833
3604 Alzheimer's Disease Human low NAA/MI(N-Acetyl Aspartate/Myo-Inositol)ratios RF 2017 28968236
3606 Alzheimer's Disease Human low serum paraoxonase activity RF 2012 20980077
3987 Lewy Body Disease Human low-density lipoprotein cholesterol (LDL-C) RF Diagnosis 2022 35124646
1870 Amyotrophic Lateral Sclerosis Human low-density lipoprotein cholesterol (LDL-C) RF Diagnosis 2023 36999624
1515 Alzheimer's Disease Human low-density lipoprotein cholesterol (LDL-C) RF 2020 32979926
1933 Alzheimer's Disease Human low-density lipoprotein cholesterol (LDL-C) RF 2020 33177243
927 Parkinson disease Human low-density lipoprotein cholesterol (LDL-C) PF Diagnosis 2023 38174461
413 Alzheimer's Disease Human low-density lipoprotein cholesterol (LDL-C) PF 2021 32766741
3607 Alzheimer's Disease Human lower plasma apoE levels RF in middle age 2009 19720974
1655 Alzheimer's Disease Human lower serum leptin levels RF 2015 26425011
812 Alzheimer's Disease Human lower serum level of folate PF 2008 18446027
3611 Alzheimer's Disease Human Manganese (Mn) deficiency RF 2017 28273828
3612 Alzheimer's Disease mice meningeal lymphatics RF wild-type mice (C57BL/6J background) 2018 30046111
3615 Alzheimer's Disease mice microglial functions(specifically microglial plaque coverage) RF APOE4 genotype 2019 31113487
1605 Alzheimer's Disease Human Midlife serum total cholesterol RF Model 2 is adjusted for age (as time scale), sex, education, race/ethnic group, midlife BMI, diabetes and hypertension; for AD, the model is additionally adjusted for late-life stroke. 2009 19648749
1617 Alzheimer's Disease Human Midlife serum total cholesterol RF Model 1 is unadjusted 2009 19648749
3619 Alzheimer's Disease Human NO(Nitric Oxide) bioavailability and cortical, extracranial, and peripheral circulation RF 2018 29593548
3679 Alzheimer's Disease Human number of functional tooth units (FTU) RF 2020 32116259
2188 Frontotemporal Lobar Degeneration Human Orthostatic hypotension (OH) RF in subjects with MCI, and patients with dementia compared to subjects with SCD 2019 31381517
2263 Frontotemporal Lobar Degeneration Human Orthostatic hypotension (OH) RF in subjects with MCI, and patients with dementia compared to subjects with SCD 2019 31381517
2189 Frontotemporal Lobar Degeneration Human Orthostatic hypotension (OH) RF in subjects with MCI, and patients with dementia compared to subjects with SCD 2019 31381517
3481 Amyotrophic Lateral Sclerosis Human Oxygen tension RF low O2 tension 2019 30863976
3710 Alzheimer's Disease Human Palmitic acid (PA) RF 2021 34151811
3622 Alzheimer's Disease Human plasma ApoE levels RF 2015 25547651
1763 Alzheimer's Disease Human Plasma clusterin levels RF elderly persons 2016 27453932
415 Alzheimer's Disease Human Plasma clusterin levels PF younger participants 2016 27453932
1487 Alzheimer's Disease Human plasma high-density lipoprotein (HDL) RF 2021 33964140
915 Alzheimer's Disease Human plasma high-density lipoprotein (HDL) PF Diagnosis 2023 35319157
3717 Alzheimer's Disease Human plasma membrane cholesterol RF 2021 33967735
3623 Parkinson disease Human Plasma Se or Fe elevation RF 2013 24340079
2831 Alzheimer's Disease Human plasma total homocysteine RF 2016 27031476
865 Parkinson disease Human plasma Zn elevation PF 2013 24340079
3130 Parkinson disease Human posterior division of the middle frontal gyrus (PMFG) RF 2021 34276350
452 Alzheimer's Disease Human pulse pressure (PP) PF 2020 32979926
3681 Alzheimer's Disease Human pulse pressure (PP) RF 2020 32960784
1543 Alzheimer's Disease Human reduced 25-hydroxyvitamin D (25[OH]D) RF 2014 23871764
3625 Parkinson disease Human Reduced serum progranulin(GRN) level RF 2013 23398167
1585 Parkinson disease Human resting heart rate (RHR) RF Diagnosis 2021 33675447
3627 Alzheimer's Disease Human serum Ang-1 RF 2012 23094194
1594 Alzheimer's Disease Human Serum apoE RF 2016 26876448
1915 Alzheimer's Disease Human serum cholesterol RF 2012 22904031
3628 Amyotrophic Lateral Sclerosis Human Serum Ferritin RF 2008 19452011
3629 Alzheimer's Disease Human serum folate RF 1998 9823829
3630 Alzheimer's Disease Human serum sEPCR levels RF 2015 25588409
3725 Alzheimer's Disease Human serum uric acid (UA) RF Low concentrations of UA 2021 33716713
3841 Parkinson disease Human serum uric acid (UA) RF Low concentrations of UA 2021 33716713
561 Parkinson disease Human serum uric acid (UA) PF 2021 33435977
394 Amyotrophic Lateral Sclerosis Human serum uric acid (UA) PF 2021 33435977
372 Parkinson disease Human serum uric acid (UA) PF 2021 33435977
395 Alzheimer's Disease Human serum uric acid (UA) PF 2021 33435977
610 Parkinson disease Human Serum vitamin B12 PF 2021 33435977
499 Parkinson disease Human Serum vitamin D PF 2021 33435977
396 Alzheimer's Disease Human Serum vitamin D PF 2021 33435977
3513 Parkinson disease Human SN hyperechogenicity (SN+) RF 2013 23115051
799 Alzheimer's Disease Human Standing height PF 2021 33718584
1602 Alzheimer's Disease Human systolic blood pressure (SBP) RF 2021 33860609
445 Alzheimer's Disease Human systolic blood pressure (SBP) PF 2020 32979926
1865 Amyotrophic Lateral Sclerosis Human systolic blood pressure (SBP) RF Diagnosis 2022 35172853
1606 Alzheimer's Disease Human systolic blood pressure (SBP) RF 2021 33860609
3632 Alzheimer's Disease Human telomere length (TL) RF shorter telomeres in AD patients 2016 27091133
1524 Alzheimer's Disease Human Testosterone RF 2021 32602403
2973 Alzheimer's Disease Human tHcy level RF 1998 9823829
1818 Alzheimer's Disease Human The highest Hcy RF 2017 28698453
1815 Alzheimer's Disease Human the lowest folate tertile RF 2017 28698453
666 Amyotrophic Lateral Sclerosis Human Thyroid PF 2016 27065942
2630 Amyotrophic Lateral Sclerosis Human toenail mercury levels RF 2018 29314106
922 Parkinson disease Human total cholesterol [TC] PF Diagnosis 2022 35723114
2013 Alzheimer's Disease Human total cholesterol [TC] RF 2020 33177243
1501 Alzheimer's Disease Human total cholesterol [TC] RF 2020 32979926
1793 Lewy Body Disease Human total homocysteine (tHcy) RF Diagnosis 2021 34720990
1822 Alzheimer's Disease Human total homocysteine (tHcy) RF Diagnosis 2021 34720990
3524 Alzheimer's Disease Human Total:HDL cholesterol (ratio) RF extrinsic epigenetic age acceleration 2018 30167451
588 Alzheimer's Disease Human treated dyslipidemia PF 2020 33126696
1521 Alzheimer's Disease Human triglyceride glucose (TyG) index RF 2021 33402193
923 Parkinson disease Human triglycerides [TG] PF Diagnosis 2022 35723114
1504 Alzheimer's Disease Human triglycerides [TG] RF 2020 32979926
1510 Alzheimer's Disease Human visual rating scale (CVRS) score RF high CVRS score 2021 33715339
3637 Frontotemporal Lobar Degeneration Human Vitamin B12 deficiency RF 2015 25722508
3764 Alzheimer's Disease Human Vitamin D levels RF 2021 33406925
3763 Alzheimer's Disease Human Vitamin D levels RF 2021 33406925
679 Alzheimer's Disease Human Vitamin D levels PF 2021 33718584
2605 Amyotrophic Lateral Sclerosis Human Age at menarche RF Prognosis postmenopausal 2023 37493444
1432 Motor Neuron Disease Human Age at menarche RF Age at menarche: >=16 1991 1745327
1441 Motor Neuron Disease Human Age at natural menopause RF Age at natural menopause: <=44 1991 1745327
906 Alzheimer's Disease Human Age at natural menopause PF Diagnosis 2023 37357294
1434 Motor Neuron Disease Human Age at natural menopause RF Age at natural menopause: 45-49 1991 1745327
2321 Alzheimer's Disease Human monozygotic(MZ) twins RF twins born in Finland before 1958 with both co-twins alive in 1967 1996 8596319
3495 Alzheimer's Disease Human pregnancy RF pregnant 5xFAD transgenic mice 2018 29855361
2977 Tourette Syndrome Human Pregnancy complications RF Less than adequate weight gain; Mutually adjusted for other variables in the model, maternal age and socioeconomic status level. 2014 24262815
3384 Alzheimer's Disease Human amnestic mild cognitive impairment (aMCI) RF 2018 30199883
1681 Alzheimer's Disease Human anemia RF 2014 24419041
1433 Amyotrophic Lateral Sclerosis Human AVM(arteriovenous malformation) RF all 2016 26260352
1436 Amyotrophic Lateral Sclerosis Human AVM(arteriovenous malformation) RF cerebral vessels 2016 26260352
1450 Parkinson disease Human Balance-Gait score RF Diagnosis 2021 33505652
2426 Alzheimer's Disease Human Blood-Stasis RF 2021 33907404
2152 Amyotrophic Lateral Sclerosis Human bulbar onset RF Diagnosis 2021 33563800
3394 Alzheimer's Disease Human carotid atherosclerosis RF 2017 28810593
3563 Alzheimer's Disease Human cerebral hypoperfusion RF 2013 23295908
3771 Alzheimer's Disease Human chronic corticosterone consumption RF Diagnosis 2021 34923495
1622 Alzheimer's Disease Human chronic periodontitis (CP) RF 10-year CP exposure 2017 28784164
1523 Parkinson disease Human chronic renal dysfunction RF Older adults 2019 31021467
3401 Parkinson disease rat Circadian rhythm dysfunction (CRD) RF 2017 27046648
3400 Amyotrophic Lateral Sclerosis Mice Circadian rhythm dysfunction (CRD) RF Transgenic mice overexpressing human SOD1 were obtained from the Nanjing Biomedical Research Institute of Nanjing University 2018 29740382
3402 Alzheimer's Disease Human cognitive impairment RF 2013 23254639
2501 Alzheimer's Disease Human cognitive impairment RF Prognosis 2022 34657824
451 Alzheimer's Disease Human Congestive heart failure PF after Hemodialysis Initiation 2018 30093374
3404 Parkinson disease Human constipation RF the relative risk was higher for men than for women 2016 27234704
3403 Alzheimer's Disease Human constipation RF colorectal cancer and AD have similar epidemiologic feature 2018 30323761
3876 Parkinson disease Human constipation RF Prognosis PD patients with constipation have a higher incidence of depression 2021 33564494
1495 Dementia with Lewy bodies Human Cortical thinning RF patients with idiopathic REM sleep behavior disorder (iRBD) 2019 31069252
3887 Tuberous sclerosis complex Human course of epilepsy RF Diagnosis 2021 33225634
3750 Alzheimer's Disease Human diagnosis of mild cognitive decline (MCI) RF 2021 33009037
1519 Parkinson disease Human dipstick-positive proteinuria RF Older adults 2019 31021467
2550 Amyotrophic Lateral Sclerosis Human dysarthria RF Diagnosis 2021 33563800
2322 Parkinson disease Human dyspepsia RF 2020 32943485
3842 Parkinson disease Human Early morning off (EMO) RF Treatment people diagnosed with Parkinson's disease (PwPD) 2021 34421569
3420 Tuberous sclerosis complex Human Early-onset and severe epilepsy RF in the first 2 years of life 2019 31538337
3426 Alzheimer's Disease Human endothelial dysfunction RF specifically loss of endothelial NO 2013 23745722
3885 Tuberous sclerosis complex Human epilepsy RF Diagnosis 2021 33225634
2555 Parkinson disease Human epilepsy RF Diagnosis 2023 36342675
3428 Tuberous sclerosis complex Human epilepsy RF 2015 26631248
3441 Tourette Syndrome Human family control and fetal anoxia RF 2012 22738448
1646 Tourette Syndrome Human Febrile convulsions(FC) RF 2014 24907027
3946 Parkinson disease Human Frailty RF Diagnosis 2023 36912851
1542 Parkinson disease Human Frailty RF Diagnosis 2023 36912851
3740 Alzheimer's Disease Human Frailty RF 2021 33586645
3754 Alzheimer's Disease Human Frailty RF These risk effects were present and similar in both carriers and non-carriers of the?APOE?ε4 allele. 2021 33188132
1574 Parkinson disease Human Freezing of gait (FOG) RF Diagnosis 2023 36166069
3868 Parkinson disease Human Freezing of gait (FOG) RF Prognosis 2021 33763009
1909 Parkinson disease Human Hearing loss (HL) RF Diagnosis 2023 36342675
1473 Alzheimer's Disease Human Hearing loss (HL) RF increase the risk of dementia 2021 34305572
1548 Alzheimer's Disease Human Hearing loss (HL) RF 2021 32959064
2421 Alzheimer's Disease Human Hearing loss (HL) RF Diagnosis 2022 35587456
1368 Alzheimer's Disease Human Hearing loss (HL) RF Diagnosis 2022 35532912
3772 Alzheimer's Disease Human hemodynamic deficits RF Diagnosis 2021 34953303
3888 Tuberous sclerosis complex Human high reported seizure frequency(HRSF) RF Diagnosis 2021 33225634
3456 Tuberous sclerosis complex Human high tuber burden RF 2017 28721058
3463 Alzheimer's Disease Human Hypercholesterolemia RF 2017 27921357
759 Amyotrophic Lateral Sclerosis Human Hypercholesterolemia PF 2014 25059395
1914 Alzheimer's Disease Human hyperhomocysteinemia RF 2014 24656904
3464 Alzheimer's Disease Human hyperhomocysteinemia RF 2013 23833960
2690 Dementia with Lewy bodies Human hyperlipidemia RF 2018 29971140
1429 Alzheimer's Disease Human hyperlipidemia RF people with mild cognitive impairment (MCI) 2011 21518614
3465 Amyotrophic Lateral Sclerosis Human hyperlipidemia RF 2019 30723964
612 Amyotrophic Lateral Sclerosis Human hyperlipidemia PF Diagnosis 2023 35983834
2876 Alzheimer's Disease Human hyperlipidemia RF 2018 29971140
1641 Alzheimer's Disease Human hyperlipidemia RF 2017 28806610
570 Amyotrophic Lateral Sclerosis Human hyperlipidemia PF 2016 27065942
2702 Dementia with Lewy bodies Human Hypertension RF 2018 29971140
3780 Amyotrophic Lateral Sclerosis Human Hypertension RF Diagnosis This study suggests that men with spinal ALS are healthier, exercise more and have lower rate of hypertension 2021 33423011
3468 Parkinson disease Human Hypertension RF 1998 9778597
1482 Parkinson disease Human Hypertension RF Diagnosis 2021 32865628
2275 Alzheimer's Disease Human Hypertension RF 2008 18288934
1394 Alzheimer's Disease Human Hypertension RF 2018 29606955
868 Alzheimer's Disease Human Hypertension PF MCI-to-dementia 2020 33088897
2351 Alzheimer's Disease Human Hypertension RF 2019 30894904
2297 Alzheimer's Disease Human Hypertension RF 2015 25624416
1355 Alzheimer's Disease Human Hypertension RF Diagnosis 2022 35532912
2003 Parkinson disease Human Hypertension RF Diagnosis 2023 36342675
2563 Alzheimer's Disease Human Hypertension RF 2018 29971140
2169 Progressive Supranuclear Palsy Human Hypertension RF 2019 31420308
2248 Alzheimer's Disease Human Hypertension RF Diagnosis 2022 35700125
382 Parkinson disease Human Hypertension PF 2021 33435977
1522 Alzheimer's Disease Human Hypertension RF after Hemodialysis Initiation 2018 30093374
2252 Alzheimer's Disease Human Hypertension RF Diagnosis 2022 35700125
3467 Alzheimer's Disease Human Hypertension RF 1995 7473847
3708 Alzheimer's Disease Human Hypertension RF 2021 34218735
603 Amyotrophic Lateral Sclerosis Human Hypertension PF 2016 27065942
2492 Alzheimer's Disease Human Hypertension RF 2010 20016220
626 Amyotrophic Lateral Sclerosis Human Hypertension PF 2019 31155341
1736 Parkinson disease Human Hypertension RF 2021 32865628
2111 Progressive Supranuclear Palsy Human Hypertension RF in the multi-variate analysis 2019 31420308
3781 Amyotrophic Lateral Sclerosis Human Hypertension RF Diagnosis females with bulbar-onset ALS are more prone to hypertension. 2021 33423011
1442 Alzheimer's Disease Human Hypertension RF people with mild cognitive impairment (MCI) 2011 21518614
430 Alzheimer's Disease Human Hypertension PF Diagnosis FOXO3 rs2802292 longevity genotype (TG/GG) 2023 37483002
1395 Alzheimer's Disease Human Hypertension RF 2015 26495049
1579 Alzheimer's Disease Human Hypertension RF 2021 33967045
1511 Parkinson disease Human Hypertension RF Diagnosis 2023 36692249
3466 Alzheimer's Disease Human Hypertension RF 2018 30149459
1551 Alzheimer's Disease Human Hypertension RF 2014 24489845
3960 Parkinson disease Human Idiopathic rapid eye movement sleep behaviour disorde RF Diagnosis 2022 34758470
3469 Parkinson disease Human Idiopathic rapid eye movement sleep behaviour disorde RF 2009 19843648
3470 Tuberous sclerosis complex Human Infantile spasms RF 2015 26631248
3735 Alzheimer's Disease Human Insulin resistance (IR) RF In non-diabetic AD 2021 33597002
3472 Alzheimer's Disease Human Insulin resistance (IR) RF 2011 20031276
3597 Alzheimer's Disease Human Insulin resistance (IR) RF 2018 30112972
3890 Tuberous sclerosis complex Human intellectual disability(ID) RF Diagnosis 2021 33225634
1466 Parkinson disease Human irritable bowel syndrome (IBS) RF Diagnosis hazard of PD was significantly higher in IBS patients only during the first two years of follow-up (aHR 2.96, 95% CI 1.78-4.92). 2021 33646176
3729 Alzheimer's Disease mice liver dysfunction RF 2021 33681678
2731 Parkinson disease Human lobar Cerebral microbleeds (MBs) RF Diagnosis 2021 33782518
3861 Parkinson disease Human long-standing cervical dystonia RF Diagnosis 2021 34015516
1439 Parkinson disease Human MCI or dementia RF Diagnosis 2021 33505652
2615 Alzheimer's Disease Human medication difficulty RF 2021 33037589
2979 Alzheimer's Disease Human medication difficulty RF 2021 33037589
1689 Alzheimer's Disease Human metabolic syndrome (MetS) RF 2021 33849249
1520 Parkinson disease Human metabolic syndrome (MetS) RF 2021 34120914
1535 Alzheimer's Disease Human metabolic syndrome (MetS) RF 2021 33849249
3892 Alzheimer's Disease Human metabolic syndrome (MetS) RF Diagnosis 2022 36744341
1963 Parkinson disease Human metabolic syndrome (MetS) RF Diagnosis 2021 32876524
1924 Parkinson disease Human non‐apnea sleep disorders (NSD) RF 2017 28470725
1742 Parkinson disease Human olfactory dysfunction RF Prognosis 2021 34014391
1555 Parkinson disease Human Osteoporosis RF Diagnosis 2021 33236101
3489 Parkinson disease rat Peripheral inflammation RF 2010 20584104
2425 Alzheimer's Disease Human Phlegm-Dampness RF 2021 33907404
2347 Tourette Syndrome Human pre-natal maternal depression RF mothers' pre-natal maternal depression affecting the offspring 2016 26174227
3498 Parkinson disease Human pretreatment motor dysfunction RF especially among older patients 1997 9447497
3866 Parkinson disease Human probable rapid eye movement sleep behavior disorder(pRBD) RF Prognosis 2021 33897604
3088 Parkinson disease Human probable rapid eye movement sleep behavior disorder(pRBD) RF Prognosis 2021 34021898
1886 Tuberous sclerosis complex Human prolonged duration of IS RF per 1-month interval 2005 16043792
1881 Tuberous sclerosis complex Human prolonged time from treatment initiation until the cessation of IS RF 2005 16043792
3500 Parkinson disease Human psychiatric disorder RF particularly in people under age 50 2008 18080857
2937 Parkinson disease Human restless leg syndrome (RLS) RF Diagnosis 2023 36342675
3075 Parkinson disease Human restless leg syndrome (RLS) RF Prognosis 2021 34955092
2887 Parkinson disease Human restless leg syndrome (RLS) RF Diagnosis even 5 to 10 years before diagnosis 2023 36342675
1379 Amyotrophic Lateral Sclerosis Human SAH(subarachnoid haemorrhage) RF Transient ischaemic attack 2016 26260352
3886 Tuberous sclerosis complex Human seizure RF Diagnosis 2021 33225634
3682 Alzheimer's Disease Human severe hypoglycaemia RF 2020 32870568
3504 Tuberous sclerosis complex Human severe mental retardation RF 2017 28721058
1404 Alzheimer's Disease Human severe OSA(obstructive sleep apnea) RF ≥30 vs. <5 apnea-hypopnea events/hour;using adjudicated outcomes 2018 28738188
1454 Alzheimer's Disease Human Severe periodontitis with tooth loss RF 2020 33124208
1767 Alzheimer's Disease Human severe PWMH RF in male 2015 26343475
3505 Parkinson disease Human Sjogren syndrome (SS) RF 2019 30946325
2581 Parkinson disease Human Stroke RF Prognosis 2021 33219665
3519 Alzheimer's Disease Human Stroke RF mediated the association between selected CV risk factors and LOAD 2016 27533593
1844 Parkinson disease Human Stroke RF 2015 26576320
1674 Alzheimer's Disease Human Stroke RF 2020 32767997
1362 Amyotrophic Lateral Sclerosis Human Stroke RF Ischaemic 2016 26260352
1384 Amyotrophic Lateral Sclerosis Human Stroke RF Unspecified 2016 26260352
485 Alzheimer's Disease Human Stroke PF Prognosis 2022 35196953
1630 Alzheimer's Disease Human Stroke RF previous stroke history 2014 24489845
3518 Alzheimer's Disease Human Stroke RF mediated the association between selected CV risk factors and LOAD 2016 27533593
2562 Parkinson disease Human Stroke RF Prognosis 2021 33219665
1366 Amyotrophic Lateral Sclerosis Human Stroke RF all 2016 26260352
3684 Amyotrophic Lateral Sclerosis Human Stroke RF 2020 32266542
3520 Parkinson disease Human Stroke RF 1998 9778597
1356 Amyotrophic Lateral Sclerosis Human Stroke RF Haemorrhagic 2016 26260352
1547 Alzheimer's Disease Human Stroke/transient ischemic attack RF after Hemodialysis Initiation 2018 30093374
3522 Tuberous sclerosis complex Human The presence of seizures RF 2011 21449900
3891 Tuberous sclerosis complex Human tuberous sclerosis–associated neuropsychiatric disorders(TANDs) RF Diagnosis 2021 33225634
1757 Dementia with Lewy bodies Human vascular cognitive impairment (VCI) RF in tremor group and non-tremor group 2020 32903761
3690 Parkinson disease Human Vascular Inflammation:blood-brain barrier(BBB) RF 2020 32733633
3713 Alzheimer's Disease Human Vascular Inflammation:blood-brain barrier(BBB) RF 2021 34041783
3829 Parkinson disease Human Vestibular dysfunction RF Diagnosis 2021 32942935
3910 Alzheimer's Disease Human visual impairment (VI) RF Prognosis 2023 36502318
1474 Parkinson disease Human visual impairment (VI) RF Diagnosis 2021 34805812
2306 Amyotrophic Lateral Sclerosis Human Age at first trauma leading to functional disability RF 35–54 years 2018 29063790
2073 Amyotrophic Lateral Sclerosis Human Age at first trauma leading to functional disability RF <35 years 2018 29063790
1795 Amyotrophic Lateral Sclerosis Human Age at first trauma leading to functional disability RF 35–54 years 2018 29063790
2819 Amyotrophic Lateral Sclerosis Human Electric current injuries RF 2018 29681882
2890 Amyotrophic Lateral Sclerosis Human Electric current injuries RF 2016 27124833
1701 Parkinson disease Human Falls RF Diagnosis 2021 33843696
1335 Parkinson disease Human falls and fractures RF Prognosis 2021 33503061
1608 Amyotrophic Lateral Sclerosis Human Fractures RF osteoporotic 2017 28316249
1632 Amyotrophic Lateral Sclerosis Human Fractures RF non-traumatic 2017 28316249
1595 Amyotrophic Lateral Sclerosis Human Fractures RF all 2017 28316249
1583 Amyotrophic Lateral Sclerosis Human Fractures RF non-osteoporotic 2017 28316249
1592 Amyotrophic Lateral Sclerosis Human Fractures RF traumatic 2017 28316249
1903 Alzheimer's Disease Human Glioma RF 2021 33718584
2442 Amyotrophic Lateral Sclerosis Human Head injury RF all cases 2009 19922125
2574 Alzheimer's Disease Human Head injury RF 2003 12707449
2835 Amyotrophic Lateral Sclerosis Human Head injury RF 2019 31155341
2124 Parkinson disease Human Head injury RF 2017 28748275
3792 Chronic Traumatic Encephalopathy Human Head injury RF Diagnosis 2021 33538222
2455 Amyotrophic Lateral Sclerosis Human Head injury RF Bulbar cases 2009 19922125
3128 Amyotrophic Lateral Sclerosis Human Head injury RF Diagnosis 2021 33621971
3450 Parkinson disease Human Head injury RF early in life 2015 25603768
2223 Amyotrophic Lateral Sclerosis Human Head injury RF 2021 33435977
2355 Amyotrophic Lateral Sclerosis Human Head injury RF Age at last injury (years)≥29 2010 20129626
2740 Alzheimer's Disease Human Head injury RF 2003 12707449
2824 Frontotemporal Dementia Human Head injury RF 2003 14617722
2983 Alzheimer's Disease Human Head injury RF 2000 10746604
1787 Amyotrophic Lateral Sclerosis Human Head injury RF Diagnosis 2021 33006184
2586 Amyotrophic Lateral Sclerosis Human Head injury RF Years between last injury and reference date <=15 years 2010 20129626
2496 Amyotrophic Lateral Sclerosis Human Head injury RF Years between last injury and reference date <=24 years 2010 20129626
2758 Amyotrophic Lateral Sclerosis Human Head injury RF 2+ Trauma 2018 29063790
2394 Amyotrophic Lateral Sclerosis Human Head injury RF 2014 25059395
2593 Amyotrophic Lateral Sclerosis Human Head injury RF Head trauma leading to functional disability 2018 29063790
3451 Parkinson disease Human Head injury RF 2002 12140099
2154 Parkinson disease Human Head injury RF 2021 33435977
1786 Amyotrophic Lateral Sclerosis Human head trauma RF with significantly greater effects for injuries occurring 10 or more years prior to symptom onset 2021 33006184
2670 Amyotrophic Lateral Sclerosis Human head trauma RF 2020 32019087
2842 Frontotemporal Dementia Human head trauma RF 2020 33138082
1798 Amyotrophic Lateral Sclerosis Human head trauma RF Diagnosis 2022 35084274
3976 Amyotrophic Lateral Sclerosis Human head trauma RF Diagnosis 2023 37166887
2879 Motor Neuron Disease Human Mechanical injuries RF Site: Column 1991 1745327
2196 Motor Neuron Disease Human Mechanical injuries RF All sites 1991 1745327
2192 Motor Neuron Disease Human Mechanical injuries RF Site: Lower limbs 1991 1745327
2827 Motor Neuron Disease Human Mechanical injuries RF Site: Trunk 1991 1745327
2662 Motor Neuron Disease Human Mechanical injuries RF Site: Upper limbs 1991 1745327
2035 Amyotrophic Lateral Sclerosis Human Moderate trauma RF 2018 29063790
3501 Chronic Traumatic Encephalopathy mice Repeated mild traumatic brain injury (r-mTBI) RF APOE3 and APOE4 specific effects following injury in a mouse model of r-mTBI 2019 30711612
1806 Amyotrophic Lateral Sclerosis Human severe electrical burns RF 2021 33006184
1807 Amyotrophic Lateral Sclerosis Human severe electrical burns RF Diagnosis 2021 33006184
2224 Amyotrophic Lateral Sclerosis Human Trauma RF Worst traumatic event reported：Moderate（Old traumatic events） 2012 22537412
2243 Amyotrophic Lateral Sclerosis Human Trauma RF Number of events leading to disability:1(All traumatic event) 2012 22537412
2399 Amyotrophic Lateral Sclerosis Human Trauma RF Worst traumatic event reported:Moderate(All traumatic event) 2012 22537412
2027 Amyotrophic Lateral Sclerosis Human Trauma RF At least one traumatic event（Old traumatic events） 2012 22537412
1893 Amyotrophic Lateral Sclerosis Human Trauma RF Diagnosis 2021 33130429
2285 Amyotrophic Lateral Sclerosis Human Trauma RF Previous trauma 2018 29681882
2577 Amyotrophic Lateral Sclerosis Human Trauma RF Worst traumatic event reported：Severe（Old traumatic events） 2012 22537412
2135 Amyotrophic Lateral Sclerosis Human Trauma RF Diagnosis 2021 33423565
2790 Amyotrophic Lateral Sclerosis Human Trauma RF Number of events reported:3+(All traumatic event) 2012 22537412
2158 Amyotrophic Lateral Sclerosis Human Trauma RF Diagnosis 2021 33130429
2303 Amyotrophic Lateral Sclerosis Human Trauma RF Number of events requiring hospitalization:1(All traumatic event) 2012 22537412
2761 Amyotrophic Lateral Sclerosis Human Trauma RF Number of events requiring hospitalization：2+（Old traumatic events） 2012 22537412
2834 Amyotrophic Lateral Sclerosis Human Trauma RF Number of events leading to disability：2+（Old traumatic events） 2012 22537412
2095 Amyotrophic Lateral Sclerosis Human Trauma RF Number of events reported:1(All traumatic event) 2012 22537412
2618 Amyotrophic Lateral Sclerosis Human Trauma RF Worst traumatic event reported:Severe(All traumatic event) 2012 22537412
2045 Amyotrophic Lateral Sclerosis Human Trauma RF 2014 25059395
1895 Amyotrophic Lateral Sclerosis Human Trauma RF 2021 33130429
2212 Amyotrophic Lateral Sclerosis Human Trauma RF At least one traumatic event(All traumatic event) 2012 22537412
2672 Amyotrophic Lateral Sclerosis Human Trauma RF Number of events reported：:3+（Old traumatic events） 2012 22537412
2157 Amyotrophic Lateral Sclerosis Human Trauma RF 2021 33130429
2299 Amyotrophic Lateral Sclerosis Human Trauma RF Number of events reported：2（Old traumatic events） 2012 22537412
2101 Amyotrophic Lateral Sclerosis Human Trauma leading to disability RF 1 Trauma 2018 29063790
1782 Amyotrophic Lateral Sclerosis Human Trauma leading to disability RF 2018 29063790
2283 Amyotrophic Lateral Sclerosis Human Trauma leading to disability RF 2+ Trauma 2018 29063790
2151 Amyotrophic Lateral Sclerosis Human Trauma leading to disability RF 2018 29063790
1781 Amyotrophic Lateral Sclerosis Human Trauma leading to disability RF 1 Trauma 2018 29063790
1789 Amyotrophic Lateral Sclerosis Human Trauma leading to disability RF 2+ Trauma 2018 29063790
2961 Frontotemporal Dementia Human traumatic brain injury (TBI) RF 2012 22465176
1363 Alzheimer's Disease Human traumatic brain injury (TBI) RF 2021 34320558
2067 Alzheimer's Disease Human traumatic brain injury (TBI) RF 2021 33435977
2209 Parkinson disease Human traumatic brain injury (TBI) RF Diagnosis 2023 36342675
3525 Alzheimer's Disease Human traumatic brain injury (TBI) RF 2015 26401777
1756 Alzheimer's Disease Human traumatic brain injury (TBI) RF Diagnosis in veteran/nonveteran males 2023 36854141
2234 Frontotemporal Lobar Degeneration Human traumatic brain injury (TBI) RF Remote TBI with extended loss of consciousness (TBI-ext) 2015 25531628
2962 Frontotemporal Lobar Degeneration Human traumatic brain injury (TBI) RF 2012 22465176
1483 Frontotemporal Dementia Human traumatic brain injury (TBI) RF 2015 25982564
2806 Frontotemporal Dementia Human traumatic brain injury (TBI) RF 2017 28946566
3526 Chronic Traumatic Encephalopathy mice traumatic brain injury (TBI) RF through the induction of tau hyperphosphorylation and aggregation 2019 31317824
2473 Parkinson disease Human traumatic brain injury (TBI) RF 2012 23150532
3527 Alzheimer's Disease Human traumatic brain injury (TBI) with reported loss of consciousness (LOC) RF 2018 29389151
3476 Amyotrophic Lateral Sclerosis Human Market-oriented skilled agricultural workers RF 2010 20012543
362 Progressive Supranuclear Palsy Human Corticoids Not Related Diagnosis 2009 19864660
361 Progressive Supranuclear Palsy Human Non-steroidal anti-inflammatory drug (except aspirin) Not Related Diagnosis 2009 19864660
360 Progressive Supranuclear Palsy Human Aspirin Not Related Diagnosis 2009 19864660
1125 Multiple System Atrophy Human Aspirin PF Diagnosis 2008 18307243
539 Parkinson disease Human Aspirin PF 2021 34494887
359 Progressive Supranuclear Palsy Human Anti-inflammatory agent Not Related Diagnosis 2009 19864660
1323 Parkinson disease Human β2-agonists PF Diagnosis 2018 30311974
1325 Parkinson disease Human β2-agonists PF Diagnosis 2018 30311974
1324 Parkinson disease Human β2-agonists PF Diagnosis 2018 30311974
2237 Parkinson disease Human Propranolol RF 2021 34598055
4372 Parkinson disease Human Propranolol RF Diagnosis 2018 30311974
4373 Parkinson disease Human Propranolol RF Diagnosis 2018 30311974
1322 Parkinson disease Human Dental Scaling PF Diagnosis Individuals aged 40-69 years, individuals without periodontal inflammatory disease (PID) showed a protective effect of dental scaling against PD development 2018 30049978
1321 Parkinson disease Human Glitazone(GTZ) PF Diagnosis People with diabetes 2017 28861893
4371 Parkinson disease Human Dental Amalgam Fillings RF Diagnosis History of Dental Amalgam Fillings 2016 27906991
4370 Parkinson disease Human Methamphetamine/amphetamine abuse RF Diagnosis (ICD-9-CM 304.4, 305.7, 969.7, E854.2） 2015 25479916
4369 Parkinson disease Human Zolpidem RF Diagnosis Zolpidem use in patients with sleep disturbance 2014 25124550
4368 Parkinson disease Human Zolpidem RF Diagnosis Zolpidem use in patients with sleep disturbance 2014 25124550
1320 Parkinson disease Human ARBs(angiotensin receptor blockers) PF Diagnosis Antihypertensive agents 2014 24910980
1319 Parkinson disease Human ACEIs(angiotensin converting enzyme inhibitors) PF Diagnosis Antihypertensive agents 2014 24910980
1318 Parkinson disease Human CCB(calcium channel blockers) PF Diagnosis Antihypertensive agents ;Centrally-acting dihydropyridine CCB use 2014 24910980
4367 Parkinson disease Human Benzamides RF Diagnosis Neuroleptics 2012 23019267
4366 Parkinson disease Human Phenothiazines RF Diagnosis Neuroleptics 2012 23019267
4365 Parkinson disease Human Neuroleptics RF Diagnosis All Neuroleptics 2012 23019267
4362 Parkinson disease Human Polypharmacy RF Diagnosis 2011 21951955
4364 Parkinson disease Human Polypharmacy RF Diagnosis 2011 21951955
4361 Parkinson disease Human Polypharmacy RF Diagnosis 2011 21951955
2131 Alzheimer's Disease Human Polypharmacy RF 2020 32251456
4363 Parkinson disease Human Polypharmacy RF Diagnosis 2011 21951955
1315 Parkinson disease Human Ibuprofen PF Diagnosis There was a dose-response relationship between tablets of ibuprofen taken per week and PD risk (p trend = 0.01). 2011 21368281
1313 Parkinson disease Human L-type calcium channel blockers PF Diagnosis 2010 20437557
1312 Parkinson disease Human Antihypertensives(Calcium channel blockers) PF Diagnosis 2008 18256367
321 Creutzfeldt-Jakob disease Human Organ transplantation Not Related Diagnosis Tanspant recipient 1999 10073510
318 Creutzfeldt-Jakob disease Human Dental treament Not Related Diagnosis 2007 17299423
320 Creutzfeldt-Jakob disease Human Dental treament Not Related Diagnosis 1999 10073510
4195 Creutzfeldt-Jakob disease Human Surgery RF Diagnosis 2002 12196646
2856 Creutzfeldt-Jakob disease Human Surgery RF orthopaedic surgery (> 1980) 2009 19144172
4192 Creutzfeldt-Jakob disease Human Surgery RF Diagnosis 1999 10073510
717 Creutzfeldt-Jakob disease Human Surgery PF undergo surgery 2008 18257690
528 Creutzfeldt-Jakob disease Human Surgery PF Tonsillectomy 2002 12196646
2117 Creutzfeldt-Jakob disease Human Surgery RF Gynecologic 2002 12196646
2313 Creutzfeldt-Jakob disease Human Surgery RF Any surgery 2002 12196646
676 Creutzfeldt-Jakob disease Human Surgery PF Surgery at any time 1988 3066847
2329 Creutzfeldt-Jakob disease Human Surgery RF undergo surgery 2008 18257690
2992 Creutzfeldt-Jakob disease Human Surgery RF orthopaedic surgery 2009 19144172
701 Creutzfeldt-Jakob disease Human Surgery PF undergo surgery;used proxy informants to acquire information about case subjects and control subjects (consistent ascertainment) 2008 18257690
4194 Creutzfeldt-Jakob disease Human Surgery RF Diagnosis 2002 12196646
2241 Creutzfeldt-Jakob disease Human Surgery RF undergo surgery;proxy informants acted only on behalf of case subjects (inconsistent data ascertainment) 2008 18257690
2174 Creutzfeldt-Jakob disease Human Surgery RF 2008 18843192
325 Creutzfeldt-Jakob disease Human Surgery Not Related Diagnosis 2002 12196646
4191 Creutzfeldt-Jakob disease Human Surgery RF Diagnosis 1999 10073510
2669 Creutzfeldt-Jakob disease Human Surgery RF predating clinical onset by 1 or more years 2008 18843192
2692 Creutzfeldt-Jakob disease Human Surgery RF ophthalmological surgery (> 1980) 2009 19144172
675 Creutzfeldt-Jakob disease Human Surgery PF Appendectomy 2002 12196646
4193 Creutzfeldt-Jakob disease Human Surgery RF Diagnosis 2002 12196646
2515 Creutzfeldt-Jakob disease Human Surgery RF 1999 10073510
4189 Creutzfeldt-Jakob disease Human Surgery RF Diagnosis 2008 18843192
2668 Creutzfeldt-Jakob disease Human Surgery RF at a 1- to 9-year time lag 2008 18843192
4188 Creutzfeldt-Jakob disease Human Medication RF Diagnosis 2009 19144172
4187 Creutzfeldt-Jakob disease Human GP visits RF Diagnosis 2009 19144172
4186 Creutzfeldt-Jakob disease Human Orthopaedic surgery RF Diagnosis 2009 19144172
4185 Creutzfeldt-Jakob disease Human Ophthalmological surgery RF Diagnosis 2009 19144172
4176 Creutzfeldt-Jakob disease Human Blood transfusion RF Diagnosis 2011 21214582
319 Creutzfeldt-Jakob disease Human Blood transfusion Not Related Diagnosis 1999 10073510
308 Creutzfeldt-Jakob disease Human Orthodontics Not Related Diagnosis 2012 23222357
307 Creutzfeldt-Jakob disease Human Haemostasis Not Related Diagnosis 2012 23222357
306 Creutzfeldt-Jakob disease Human Intravenous sedation Not Related Diagnosis 2012 23222357
305 Creutzfeldt-Jakob disease Human Surgical extractions Not Related Diagnosis 2012 23222357
304 Creutzfeldt-Jakob disease Human Periodontal treatment Not Related Diagnosis 2012 23222357
303 Creutzfeldt-Jakob disease Human Other minor oral surgery Not Related Diagnosis 2012 23222357
302 Creutzfeldt-Jakob disease Human Root canal treatment Not Related Diagnosis 2012 23222357
301 Creutzfeldt-Jakob disease Human Non-surgical extractions Not Related Diagnosis 2012 23222357
300 Creutzfeldt-Jakob disease Human Extensive fillings Not Related Diagnosis 2012 23222357
299 Creutzfeldt-Jakob disease Human Minimal fillings Not Related Diagnosis 2012 23222357
298 Creutzfeldt-Jakob disease Human Basic periodontal examination Not Related Diagnosis 2012 23222357
290 Amyotrophic Lateral Sclerosis Human Surgical operations Not Related Diagnosis 1991 1798425
1082 Alzheimer's Disease Human Music therapy PF Treatment 2009 19628939
1081 Alzheimer's Disease Human Cognitive stimulation therapy PF Treatment 2010 20713437
1076 Alzheimer's Disease Human Atorvastatin PF Prognosis 2005 15974900
68 Alzheimer's Disease Human Simvastatin Not Related Prognosis 2011 21795660
66 Alzheimer's Disease Human NSAIDs Not Related Diagnosis 2008 18519870
67 Alzheimer's Disease Human NSAIDs Not Related Diagnosis 1998 10192221
343 Parkinson disease Human NSAIDs Not Related Diagnosis 2007 17851257
1316 Parkinson disease Human Statin PF Diagnosis 2012 22410446
1079 Alzheimer's Disease Human Statin PF Diagnosis 2010 20533968
1788 Parkinson disease Human Statin RF Diagnosis hyperlipidemia 2022 35276584
1078 Alzheimer's Disease Human Statin PF Diagnosis 2009 18931004
1774 Parkinson disease Human Statin RF Diagnosis hyperlipidemia 2022 35276584
1317 Parkinson disease Human Statin PF Diagnosis Statin treatment 2013 24304212
1075 Alzheimer's Disease Human Statin PF Prognosis 2015 25408208
1080 Alzheimer's Disease Human Statin PF Diagnosis 2006 19595865
378 Alzheimer's Disease Human Statin PF 2021 33435977
1314 Parkinson disease Human Statin PF Diagnosis Short-term ( 2010 20629142
1077 Alzheimer's Disease Human Statin PF Diagnosis 2004 14739574
384 Parkinson disease Human Statin PF 2021 33435977
1823 Amyotrophic Lateral Sclerosis Human Toxics RF Diagnosis 2023 37993052
1820 Amyotrophic Lateral Sclerosis Human Toxics RF Diagnosis 2023 37993052
1814 Amyotrophic Lateral Sclerosis Human Toxics RF Diagnosis 2023 37993052
1824 Amyotrophic Lateral Sclerosis Human Toxics RF Diagnosis 2023 37993052
1811 Amyotrophic Lateral Sclerosis Human Toxics RF Diagnosis 2023 37993052
2414 Multiple System Atrophy Human plant and machine operators and assemblers RF 2008 18307243
3031 Multiple System Atrophy Human plant and machine operators and assemblers RF ≤ 11 years 2008 18307243
2777 Multiple System Atrophy Human plant and machine operators and assemblers RF ≥ 11years 2008 18307243
2989 Motor Neuron Disease Human Fungicides RF Diagnosis 2022 35318275
354 Progressive Supranuclear Palsy Human Living in village or isolated farm Not Related Diagnosis 2009 19864660
1328 Progressive Supranuclear Palsy Human Firearm usage PF Diagnosis 2018 29973911
4358 Parkinson disease Human Sunflowers RF Diagnosis Crop exposure 2018 29136149
4357 Parkinson disease Human Wheat/Barley RF Diagnosis Crop exposure 2018 29136149
4356 Parkinson disease Human Cattle RF Diagnosis Animal exposure 2018 29136149
4355 Parkinson disease Human Vegetables RF Diagnosis Crop exposure 2018 29136149
4354 Parkinson disease Human Fruit-growing RF Diagnosis Crop exposure 2018 29136149
4352 Parkinson disease Human Rape RF Diagnosis Crop exposure 2018 29136149
4351 Parkinson disease Human Beet RF Diagnosis Crop exposure 2018 29136149
4350 Parkinson disease Human Peas RF Diagnosis Crop exposure 2018 29136149
4349 Parkinson disease Human Corn RF Diagnosis Crop exposure 2018 29136149
4348 Parkinson disease Human Poultry RF Diagnosis Animal exposure 2018 29136149
4347 Parkinson disease Human Horse RF Diagnosis Animal exposure 2018 29136149
4346 Parkinson disease Human Swine RF Diagnosis Animal exposure 2018 29136149
4345 Parkinson disease Human Bulb cultivation RF Diagnosis 2017 28704700
4343 Parkinson disease Human SO2 RF Prognosis A unit increase in 8-day moving average of concentrations was significantly associated with PD aggravation. 2017 28300224
4342 Parkinson disease Human NO2 RF Prognosis A unit increase in 8-day moving average of concentrations was significantly associated with PD aggravation. 2017 28300224
4340 Parkinson disease Human Organophosphate(OP) or Carbamate poisoning(CM) RF Diagnosis 2017 27781262
4339 Parkinson disease Human CO RF Diagnosis 2016 27614945
4344 Parkinson disease Human CO RF Prognosis A unit increase in 8-day moving average of concentrations was significantly associated with PD aggravation. 2017 28300224
4338 Parkinson disease Human NOx RF Diagnosis 2016 27614945
4337 Parkinson disease Human PM10 RF Diagnosis Among female non-smokers 2016 27285422
3951 Parkinson disease Human PM2.5 RF Diagnosis 2023 37903644
1496 Alzheimer's Disease Human PM2.5 RF Diagnosis male, with old age, with low education levels, used to work as farmers or blue-collar workers before retirement, overweight and obese were associated with a higher effect of PM2.5 2022 36447194
3913 Alzheimer's Disease Human PM2.5 RF Diagnosis 2023 35436383
4336 Parkinson disease Human PM2.5 RF Diagnosis Among female non-smokers 2016 27285422
4341 Parkinson disease Human PM2.5 RF Prognosis A unit increase in 8-day moving average of concentrations was significantly associated with PD aggravation. 2017 28300224
4360 Parkinson disease Human PM2.5 RF Diagnosis 2018 30124852
1310 Parkinson disease Human Sunlight exposure PF Diagnosis 2016 26959053
4335 Parkinson disease Human Occupational complexity RF Diagnosis 2015 26444091
4334 Parkinson disease Human Pesticide exposure RF Diagnosis 2015 26345784
3958 Parkinson disease Human Pesticide exposure RF Diagnosis 2022 34758470
4333 Parkinson disease Human Capital city RF Diagnosis 2016 26151951
1309 Parkinson disease Human Artistic occupations PF Diagnosis 2015 26138540
1311 Parkinson disease Human Artistic occupations PF Diagnosis Pooled odds ratios for PD across the Rotterdam and Radboud studies 2018 30007105
342 Parkinson disease Human Working night shifts Not Related Diagnosis 2015 25950750
4331 Parkinson disease Human High complexity of work with people RF Diagnosis 2014 25198429
4330 Parkinson disease Human High complexity of work with data RF Diagnosis 2014 25198429
4329 Parkinson disease Human Chemical exposure RF Diagnosis 2014 25097376
4328 Parkinson disease Human Exposure to anesthetic gases RF Diagnosis 2013 24321326
4327 Parkinson disease Human Evening work RF Diagnosis 2013 24125560
4326 Parkinson disease Human OP pesticides RF Diagnosis OP(organophosphorus ) 2013 24057998
341 Parkinson disease Human Outdoor work Not Related Diagnosis 2013 24044947
1308 Parkinson disease Human WBV(whole-body vibration ) PF Diagnosis 2012 22798480
4325 Parkinson disease Human Trichloroethylene(TCE) RF Diagnosis Solvent exposures 2012 22083847
1307 Parkinson disease Human Professional or technical occupation PF Diagnosis 2011 21733194
4324 Parkinson disease Human Combined exposure to ziram, maneb, and paraquat RF Diagnosis 2011 21505849
1305 Parkinson disease Human Working outdoors PF Diagnosis Frequent outdoor work(Postmen, window cleaners, millers, shipbuilders, building painters, joiners, seamen and bricklayers) 2011 20884793
1306 Parkinson disease Human Working outdoors PF Diagnosis Maximal outdoor work(Farmers, chimneysweeps, frogmen, smallholders, farmhands, farm workers, gardeners, foresters, well diggers and pavers) 2011 20884793
340 Parkinson disease Human Working outdoors Not Related Diagnosis Moderate outdoor work(Nursery or kindergarten teachers, station personnel, filling-station attendants, estate agents, firemen, policemen, miners and electricians) 2011 20884793
1304 Parkinson disease Human Service-sector worker PF Diagnosis 2010 20402575
4323 Parkinson disease Human Naphtha and its derivates RF Diagnosis 2010 20402575
4322 Parkinson disease Human Dyes RF Diagnosis 2010 20402575
4320 Parkinson disease Human Gardening RF Diagnosis 2010 20402575
4319 Parkinson disease Human Exposure to pesticides, herbicides and insecticides RF Diagnosis 2010 20353703
4318 Parkinson disease Human Blue collar occupations RF Diagnosis 2010 20353703
4313 Parkinson disease Human Occupational exposure to Pb RF Diagnosis μg/g(micrograms Pb storage per gram of bone) 2006 17185278
4311 Parkinson disease Human History of heavy metal and toxin exposure RF Diagnosis 2003 14607318
4308 Parkinson disease Human Plantation RF Diagnosis 2002 12433267
4307 Parkinson disease Human Farming as an occupation RF Diagnosis 2002 11903115
4306 Parkinson disease Human Work in construction RF Diagnosis 2001 11383940
3060 Motor Neuron Disease Human Insecticides RF Diagnosis 2022 35318275
2802 Motor Neuron Disease Human Insecticides RF Diagnosis 2022 35318275
4321 Parkinson disease Human Insecticides RF Diagnosis 2010 20402575
2820 Motor Neuron Disease Human Insecticides RF Diagnosis 2022 35318275
4300 Parkinson disease Human Insecticides RF Diagnosis 1998 9595985
4299 Parkinson disease Human Herbicides RF Diagnosis 1998 9595985
3848 Parkinson disease Human Herbicides RF 2021 34421783
4298 Parkinson disease Human Farming as an occupation after age 18 RF Diagnosis 1998 9595985
4305 Parkinson disease Human Iron-copper RF Diagnosis 1999 10385887
4297 Parkinson disease Human Iron-copper RF Diagnosis 1997 9065542
4304 Parkinson disease Human Lead-iron RF Diagnosis 1999 10385887
4296 Parkinson disease Human Lead-iron RF Diagnosis 1997 9065542
4303 Parkinson disease Human Lead-copper RF Diagnosis 1999 10385887
4295 Parkinson disease Human Lead-copper RF Diagnosis 1997 9065542
4301 Parkinson disease Human Manganese RF Diagnosis 1999 10385887
3610 Motor Neuron Disease Human Manganese RF excess intake of manganese from food 1994 8029710
3943 Alzheimer's Disease Human Manganese RF Diagnosis APOE e4 allele 2023 37579537
4294 Parkinson disease Human Manganese RF Diagnosis 1997 9065542
4293 Parkinson disease Human Copper RF Diagnosis 1997 9065542
4302 Parkinson disease Human Copper RF Diagnosis 1999 10385887
3567 Motor Neuron Disease horse Copper RF 2006 16426221
4317 Parkinson disease Human Pesticide RF Diagnosis 2009 19847896
4309 Parkinson disease Human Pesticide RF Diagnosis 2003 12902626
4332 Parkinson disease Human Pesticide RF Diagnosis Pesticide exposure in farms that specialized in vineyards 2015 25815770
4314 Parkinson disease Human Pesticide RF Diagnosis 2007 17188257
4316 Parkinson disease Human Pesticide RF Diagnosis 2008 18373838
4310 Parkinson disease Human Pesticide RF Diagnosis 2003 12956856
4292 Parkinson disease Human Pesticide RF Diagnosis 1993 8414014
4315 Parkinson disease Human Pesticide RF Diagnosis Age≤59.8 years 2008 18322262
1302 Parkinson disease Human Wheat growing PF Diagnosis 1989 2710356
2996 Amyotrophic Lateral Sclerosis Human industrial chemicals RF residents of New England or the bordering New York region at the time of enrollment 2017 28122372
2943 Amyotrophic Lateral Sclerosis Human industrial chemicals RF residents of New England or the bordering New York region at the time of enrollment 2017 28122372
4148 Bovine Spongiform Encephalopathy Cattle Keeping livestock other than cattle RF Diagnosis 2006 16930273
4146 Bovine Spongiform Encephalopathy Cattle Herd size RF Diagnosis 2007 17097171
4147 Bovine Spongiform Encephalopathy Cattle Herd size RF Diagnosis 2007 17097171
2722 Parkinson disease Human Metals RF 2020 32943485
2001 Amyotrophic Lateral Sclerosis Human Pesticides RF Diagnosis 2021 34562505
1303 Parkinson disease Human Pesticides PF Diagnosis 2006 16773614
1587 Parkinson disease Human Pesticides RF Prognosis 2021 33278869
2732 Parkinson disease Human Pesticides RF 2021 34494887
3847 Parkinson disease Human Pesticides RF 2021 34421783
2084 Parkinson disease Human Pesticides RF 2021 33435977
2809 Frontotemporal Dementia Human Pesticides RF Insecticides,Herbicides,Fungicides 2020 33138082
1978 Amyotrophic Lateral Sclerosis Human Pesticides RF Diagnosis 2021 34562505
2271 Motor Neuron Disease Human Pesticides RF Diagnosis 2022 35318275
2026 Amyotrophic Lateral Sclerosis Human Pesticides RF Diagnosis 2021 34562505
2207 Amyotrophic Lateral Sclerosis Human Pesticides RF 2021 33435977
1977 Amyotrophic Lateral Sclerosis Human Pesticides RF Diagnosis 2021 34562505
4312 Parkinson disease Human Pesticides RF Diagnosis 2006 16802290
2494 Amyotrophic Lateral Sclerosis Human Electric shock RF 2020 32019087
1953 Parkinson disease Human Organic solvents RF 2021 33435977
2083 Amyotrophic Lateral Sclerosis Human Organic solvents RF 2018 29681882
2420 Alzheimer's Disease Human Dieldrin RF 2012 22904031
1810 Amyotrophic Lateral Sclerosis Human Lead RF Diagnosis Exposures to lead 20 or more years prior to diagnosis had larger effect sizes compared to those occurring more recently. 2021 33006184
2198 Amyotrophic Lateral Sclerosis Human Lead RF Diagnosis 2022 35041949
2531 Amyotrophic Lateral Sclerosis Human Lead RF Diagnosis 2021 33130429
3941 Alzheimer's Disease mice Lead RF Diagnosis 2023 38091880
2624 Amyotrophic Lateral Sclerosis Human Lead RF Diagnosis 2022 35041949
1794 Amyotrophic Lateral Sclerosis Human Lead RF Diagnosis 2021 33068316
1801 Amyotrophic Lateral Sclerosis Human Lead RF Diagnosis 2021 34137650
1990 Amyotrophic Lateral Sclerosis Human Lead RF environmental/occupational 2020 31578652
1299 Parkinson disease Human Lifetime exposure to estrogens PF Diagnosis 2014 25179495
1298 Parkinson disease Human High estrogen oral contraceptives PF Diagnosis 2014 24750445
4287 Parkinson disease Human Menopausal hormone RF Diagnosis 2014 24352877
4286 Parkinson disease Human Oral contraceptives RF Diagnosis 2011 21956541
1297 Parkinson disease Human Oral contraceptives PF Diagnosis 2014 24352877
4282 Parkinson disease Human Surgical menopause RF Diagnosis 2004 15184606
4281 Parkinson disease Human Pregnancies RF Diagnosis 2004 15184606
4280 Parkinson disease Human Age of mother at subject's birth RF Diagnosis The age of the mother at subject's birth was signifcantly older in cases (27.4 years, SD 5.9) than in controls (25.1 years, SD 5.8, P < 0.005). 2002 11903115
4279 Parkinson disease Human Children RF Diagnosis 2001 11359079
4285 Parkinson disease Human Children RF Diagnosis 2007 17265462
4284 Parkinson disease Human Children RF Diagnosis 2007 17265462
3059 Creutzfeldt-Jakob disease Human regular GP visits RF 2009 19144172
3490 Alzheimer's Disease Human personal experience with AD RF 2017 28605999
4197 Creutzfeldt-Jakob disease Human Psychiatric visit RF Diagnosis 2002 12196646
2658 Creutzfeldt-Jakob disease Human Psychiatric visit RF 2002 12196646
4055 Alzheimer's Disease Human Occupational attainment RF Diagnosis 1994 8139057
4258 Parkinson disease Human General anaesthesia RF Diagnosis 2002 11903115
1686 Alzheimer's Disease Human Sleep disturbance RF Model 4: Main effects adjusted for adjusted for sex, age, education, race, e4 carrier status, the presence of hypertension and hypercholesterolemia 2018 29077487
1560 Parkinson disease Human Sleep disturbance RF Diagnosis 2022 35013056
4039 Alzheimer's Disease Human Sleep disturbance RF Diagnosis 2018 29077487
1688 Alzheimer's Disease Human Sleep disturbance RF Model 2: Main effects adjusted for sex, education, age, and race. 2018 29077487
1514 Parkinson disease Human Sleep disturbance RF Diagnosis 2022 35013056
1687 Alzheimer's Disease Human Sleep disturbance RF Model 3: Main effects adjusted for adjusted for sex, age, education, race, e4 carrier status 2018 29077487
1696 Alzheimer's Disease Human Sleep disturbance RF Model 1: Main effect unadjusted 2018 29077487
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