| RF_ID |
Disease Name |
2ndClass |
3rdClass |
4thClass |
Species |
RF_Name |
Association |
Condition |
PMID |
| 1549 |
Alzheimer's Disease |
Habit |
Sleeping |
|
Human |
napping |
RF |
|
34109847 |
| 1550 |
Parkinson disease |
Habit |
Sleeping |
|
Human |
Long sleep |
RF |
|
35013056 |
| 1591 |
Alzheimer's Disease |
Habit |
Sleeping |
|
Human |
Long sleep |
RF |
|
34109847 |
| 1873 |
Amyotrophic Lateral Sclerosis |
habit |
Smoking |
|
Human |
Age at cessation of smoking |
RF |
|
16963407 |
| 421 |
Alzheimer's Disease |
habit |
Sleeping |
|
Human |
Better sleep consolidation attenuate |
PF |
in APOE e4 carriers |
24145819 |
| 3398 |
Alzheimer's Disease |
habit |
Sleeping |
|
mice |
Chronic Sleep Deprivation(SD) |
RF |
|
26757041 |
| 722 |
Alzheimer's Disease |
habit |
Sleeping |
|
Human |
daytime napping |
PF |
|
33150399 |
| 725 |
Alzheimer's Disease |
habit |
Sleeping |
|
Human |
daytime napping |
PF |
|
33150399 |
| 3784 |
Amyotrophic Lateral Sclerosis |
habit |
Sleeping |
|
Human |
daytime sleepiness |
RF |
|
34130902 |
| 1847 |
Amyotrophic Lateral Sclerosis |
habit |
Sleeping |
|
Human |
daytime sleepiness |
RF |
|
34130902 |
| 4196 |
Creutzfeldt-Jakob disease |
habit |
Behavior |
Individual Behavior |
Human |
Ear piercing |
RF |
|
12196646 |
| 2187 |
Creutzfeldt-Jakob disease |
habit |
Behavior |
Individual Behavior |
Human |
Ear piercing |
RF |
females only |
12196646 |
| 3822 |
Multiple System Atrophy |
habit |
Sleeping |
|
Human |
Excessive daytime sleepiness (EDS) |
RF |
with the non-motor dysfunction |
35087473 |
| 1706 |
Alzheimer's Disease |
habit |
Smoking |
|
Human |
Exposure to secondhand smoke |
RF |
|
34101793 |
| 1724 |
Frontotemporal Lobar Degeneration |
habit |
Behavior |
Social Behavior |
Human |
Familial aggregation |
RF |
first-degree relatives (parents and siblings) of frontotemporal dementia (FTD) patients |
9633692 |
| 2502 |
Creutzfeldt-Jakob disease |
habit |
keeping a pet |
|
Human |
Ferret contact |
RF |
|
3066847 |
| 3803 |
Lewy Body Disease |
habit |
travel |
|
Human |
first-generation immigrants (FGI) |
RF |
patients born in Belgium (PBIB) |
32931000 |
| 1809 |
Amyotrophic Lateral Sclerosis |
habit |
Behavior |
Individual Behavior |
Human |
Hobbies involving lead |
RF |
Exposures to lead 20 or more years prior to diagnosis had larger effect sizes compared to those occurring more recently. |
33006184 |
| 1336 |
Alzheimer's Disease |
habit |
Sleeping |
|
Human |
Insomnia |
RF |
|
34025548 |
| 1785 |
Alzheimer's Disease |
habit |
Sleeping |
|
Human |
Insomnia |
RF |
|
37269705 |
| 2469 |
Creutzfeldt-Jakob disease |
habit |
keeping a pet |
|
Human |
Keeping cats |
RF |
|
3066847 |
| 2960 |
Creutzfeldt-Jakob disease |
habit |
keeping a pet |
|
Human |
Pets |
RF |
other than cats/dogs |
3066847 |
| 910 |
Alzheimer's Disease |
habit |
Sleeping |
|
Human |
sleep quality |
PF |
ABCA7 rs115550680 G allele carriers |
37212111 |
| 2210 |
Parkinson disease |
habit |
Sleeping |
|
Human |
sleep quality |
RF |
|
36342675 |
| 3857 |
Parkinson disease |
habit |
Sleeping |
|
Human |
sleep quality |
RF |
periodic limb movements during sleep (PLMS) was the risk factor that influenced the objective sleep quality in PD patients with RLS |
34177757 |
| 2919 |
Tourette Syndrome |
habit |
Smoking |
|
Human |
Prenatal maternal smoking |
RF |
Prenatal maternal smoking affecting the offspring |
25796373 |
| 3743 |
Alzheimer's Disease |
habit |
Behavior |
Individual Behavior |
Human |
sedentary lifestyle |
RF |
|
33527694 |
| 3716 |
Alzheimer's Disease |
habit |
Sleeping |
|
mice |
Sleep deprivation (SD) |
RF |
|
34087256 |
| 3721 |
Alzheimer's Disease |
habit |
Sleeping |
|
Human |
sleep efficiency |
RF |
especially in the presence of β-amyloid (Aβ) accumulation |
33912975 |
| 824 |
Alzheimer's Disease |
habit |
Sleeping |
|
Human |
sleep efficiency |
PF |
|
34130902 |
| 438 |
Alzheimer's Disease |
habit |
Sleeping |
|
Human |
sleep efficiency |
PF |
|
35697505 |
| 434 |
Alzheimer's Disease |
habit |
Sleeping |
|
Human |
sleep efficiency |
PF |
|
35697505 |
| 888 |
Alzheimer's Disease |
habit |
Sleeping |
|
Human |
sleep efficiency |
PF |
|
34130902 |
| 3506 |
Alzheimer's Disease |
habit |
Sleeping |
|
Human |
Sleep-wake regulation |
RF |
|
30649520 |
| 3727 |
Alzheimer's Disease |
habit |
Behavior |
Social Behavior |
Human |
social networks |
RF |
|
33749650 |
| 895 |
Parkinson disease |
habit |
Smoking |
|
Human |
tobacco |
PF |
|
34421783 |
| 4359 |
Parkinson disease |
habit |
Smoking |
|
Human |
Tobacco |
RF |
Crop exposure |
29136149 |
| 3535 |
Alzheimer's Disease |
habit |
travel |
|
Human |
Wandering |
RF |
exhibit wandering in the middle or late stages |
8422268 |
| 477 |
Amyotrophic Lateral Sclerosis |
habit |
Behavior |
Social Behavior |
Human |
Work |
PF |
Significant adjusted OR |
24706338 |
| 726 |
Amyotrophic Lateral Sclerosis |
habit |
Behavior |
Social Behavior |
Human |
Work |
PF |
|
24706338 |
| 4262 |
Parkinson disease |
Habit |
Sleeping |
|
Human |
EDS(Excessive daytime sleepiness) |
RF |
men with EDS reported napping longer than men without EDS (69 vs 42 minutes, p 0.001). An excess of insomnia was also observed in men with EDS (39.0% with EDS and 28.7% without EDS, p 0.001). In addition, grogginess was more likely in the presence of EDS (13%) vs its absence (2.5%, p 0.001), and |
16275833 |
| 351 |
Progressive Supranuclear Palsy |
Habit |
Smoking |
|
Human |
Smoking types |
Not Related |
|
19864660 |
| 350 |
Progressive Supranuclear Palsy |
Habit |
Smoking |
|
Human |
Smoking types |
Not Related |
|
19864660 |
| 1244 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Suns |
PF |
|
28338925 |
| 1241 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Suns(Moist smokeless tobacco ) |
PF |
|
27940486 |
| 1243 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Suns(Moist smokeless tobacco ) |
PF |
|
27940486 |
| 1240 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Suns(Moist smokeless tobacco ) |
PF |
|
27940486 |
| 1242 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Suns(Moist smokeless tobacco ) |
PF |
|
27940486 |
| 1232 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Time-since-cessation (years) |
PF |
|
24788751 |
| 1231 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Time-since-cessation (years) |
PF |
|
24788751 |
| 1233 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Time-since-cessation (years) |
PF |
|
24788751 |
| 1230 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Time-since-cessation (years) |
PF |
|
24788751 |
| 339 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Passive smoking |
Not Related |
|
20175761 |
| 338 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Passive smoking |
Not Related |
|
20175761 |
| 1218 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Passive smoking |
PF |
Among persons whose only tobacco smoke exposure was passive smoking at home, risk was inversely associated with years exposed. |
22095755 |
| 1203 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Cigarette equivalents |
PF |
|
15521056 |
| 1202 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Cigarette equivalents |
PF |
|
15521056 |
| 1191 |
Parkinson disease |
Habit |
Keeping a pet |
|
Human |
Exposure to pets |
PF |
|
11574106 |
| 4166 |
Creutzfeldt-Jakob disease |
Habit |
Travel |
|
Human |
Frequent travels abroad |
RF |
|
19144172 |
| 365 |
Alzheimer's Disease |
Habit |
Reading |
|
Human |
Reading |
PF |
people with mild cognitive impairment (MCI) |
21518614 |
| 1629 |
Alzheimer's Disease |
Habit |
Reading |
|
Human |
Reading |
RF |
reading occasionally |
28806610 |
| 1101 |
Amyotrophic Lateral Sclerosis |
Habit |
Reading |
|
Human |
Reading |
PF |
|
31155341 |
| 509 |
Amyotrophic Lateral Sclerosis |
Habit |
Reading |
|
Human |
Reading |
PF |
|
31155341 |
| 274 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Snuff dipping |
Not Related |
|
17106211 |
| 1099 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Time-sice-quiting |
PF |
|
31434759 |
| 1098 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Time-sice-quiting |
PF |
|
31434759 |
| 269 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking amount |
Not Related |
|
20129626 |
| 4084 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking amount |
RF |
|
31434759 |
| 268 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking amount |
Not Related |
|
20129626 |
| 4097 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking amount |
RF |
|
10645818 |
| 270 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking amount |
Not Related |
|
20129626 |
| 267 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking amount |
Not Related |
|
20129626 |
| 4096 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking duration |
RF |
|
10645818 |
| 266 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking duration |
Not Related |
|
20129626 |
| 263 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking duration |
Not Related |
|
20129626 |
| 265 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking duration |
Not Related |
|
20129626 |
| 4083 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking duration |
RF |
|
31434759 |
| 264 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking duration |
Not Related |
|
20129626 |
| 255 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
Not Related |
|
22377752 |
| 4099 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
RF |
|
15668420 |
| 4090 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
RF |
|
20074360 |
| 272 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
Not Related |
|
20074360 |
| 260 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
Not Related |
|
22377752 |
| 257 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
Not Related |
|
22377752 |
| 254 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
Not Related |
|
19342254 |
| 4095 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
RF |
|
10645818 |
| 4089 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
RF |
|
21320987 |
| 271 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
Not Related |
|
20074360 |
| 4086 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
RF |
|
27656044 |
| 262 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
Not Related |
|
20129626 |
| 259 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
Not Related |
|
22377752 |
| 455 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking status |
PF |
|
35697505 |
| 256 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
Not Related |
|
22377752 |
| 1100 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
PF |
|
15229114 |
| 4094 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
RF |
|
15229114 |
| 4091 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
RF |
|
20074360 |
| 4088 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
RF |
|
21320987 |
| 4085 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
RF |
|
30786056 |
| 4082 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
RF |
|
31434759 |
| 261 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
Not Related |
|
20129626 |
| 258 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking status |
Not Related |
|
22377752 |
| 449 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking status |
PF |
|
35697505 |
| 4081 |
Amyotrophic Lateral Sclerosis |
Habit |
Behavior |
|
Human |
Behavior |
RF |
Type A behavior patterns were assessed
by a 10-item scale specifically designed by Maeda for
Japanese persons. These were dichotomized into type A
(>17 points) and non–type A (<18) according to the
criteria of Maeda. |
19342254 |
| 1026 |
Alzheimer's Disease |
Habit |
Attitude |
|
Human |
Conscientiousness |
PF |
|
20973606 |
| 1183 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
8209872 |
| 1215 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
20220126 |
| 1469 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Current smokers |
19399866 |
| 48 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
Not Related |
|
1550089 |
| 1212 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
20220126 |
| 1415 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Pack-years smoked 21-35 (Adjusted for Age) |
21320987 |
| 2446 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
RF |
subjective cognitive decline (SCD) |
35587456 |
| 1025 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
9152711 |
| 1209 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
20175761 |
| 1407 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Pack-years smoked 21-35 (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
| 2265 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Cumulative pack-years<20 pack-years(Adjustment for education and alcohol consumption) |
10645818 |
| 3512 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
RF |
intrinsic epigenetic age acceleration; current smoker (N=939); former smoker, stopped within past 12 months (N=158); former smoker, stopped more than 12 months ago (N=1309); never smoker (N=2533), and not coded (N=62). |
30167451 |
| 329 |
Multiple System Atrophy |
Habit |
Smoking |
|
Human |
Smoking |
Not Related |
|
10636135 |
| 1206 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
20175761 |
| 1238 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
26952952 |
| 1399 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Pack-years smoked ≤20 (Adjusted for Age) |
21320987 |
| 2193 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Cumulative pack-years<20 pack-years(Adjustment for education) |
10645818 |
| 3509 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
RF |
|
23422663 |
| 1235 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
25514902 |
| 1387 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
RF |
|
26495049 |
| 2055 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
current smokers |
22791740 |
| 4093 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
|
17923612 |
| 275 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
Not Related |
|
1798425 |
| 854 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
19188574 |
| 1382 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Ever smokers (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
| 1956 |
Frontotemporal Dementia |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Passive smoking exposure |
33138082 |
| 3000 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Combination recency and
dose:Current, <20 pack years(Adjustment for education) |
10645818 |
| 1200 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
15468111 |
| 4087 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
|
22791740 |
| 750 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
34633332 |
| 1197 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
The inverse correlation between Parkinson's disease risk and smoking as well as the trend of gradient dose response is again observed in our study. |
12964791 |
| 1229 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
24788751 |
| 1374 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Ever smokers (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
| 1828 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
RF |
|
34082149 |
| 724 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
32943485 |
| 1194 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
11761476 |
| 1226 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
24788751 |
| 1371 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Pack-years smoked > 35 (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
| 2850 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Current smoker(Adjustment for education and alcohol consumption) |
10645818 |
| 582 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
21059511 |
| 1223 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
24788751 |
| 1364 |
Tourette Syndrome |
Habit |
Smoking |
|
Human |
Smoking |
RF |
|
33371659 |
| 2810 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
|
31155341 |
| 1188 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
11359079 |
| 1220 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
24633681 |
| 1358 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Pack-years smoked ≤20 (Adjusted for Age) |
21320987 |
| 2671 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Bulbar cases |
19922125 |
| 4036 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
RF |
|
16493200 |
| 1350 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Former smokers (Adjusted for Age) |
21320987 |
| 1472 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Time spent smoking≥30years |
19399866 |
| 2507 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Cumulative pack-years≥20 pack-years(Adjustment for education) |
10645818 |
| 1185 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
10581500 |
| 1217 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
20603187 |
| 414 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
30772279 |
| 1214 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
20220126 |
| 1246 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
29667433 |
| 1451 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
RF |
in APOE e4 carriers |
20847559 |
| 2470 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Ever smoker(Adjustment for education and alcohol consumption) |
10645818 |
| 1211 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
20220126 |
| 1409 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Pack-years smoked >35(Adjusted for Age) |
21320987 |
| 2373 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Ever smoker(Adjustment for education) |
10645818 |
| 1024 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
30792733 |
| 1208 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
20175761 |
| 1401 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Former smokers (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
| 2262 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Current(Crude OR) |
17923612 |
| 3511 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
RF |
|
24596166 |
| 4098 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
|
10364720 |
| 328 |
Multiple System Atrophy |
Habit |
Smoking |
|
Human |
Smoking |
Not Related |
|
10636135 |
| 1205 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
19513320 |
| 1237 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
26952952 |
| 1398 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Pack-years smoked >35(Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
| 3508 |
Tourette Syndrome |
Habit |
Smoking |
|
Human |
Smoking |
RF |
maternal smoking |
22738448 |
| 1234 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
25514902 |
| 1386 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
RF |
|
29606955 |
| 2015 |
Frontotemporal Dementia |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Ever smoking |
33138082 |
| 4092 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
|
19399866 |
| 853 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
11060508 |
| 2978 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Bulbar cases |
19922125 |
| 820 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
30792733 |
| 1199 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
14607318 |
| 1378 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Former smokers (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
| 1196 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
The inverse correlation between Parkinson's disease risk and smoking as well as the trend of gradient dose response is again observed in our study. |
12964791 |
| 1228 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
24788751 |
| 1373 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Pack-years smoked > 35 (Adjusted for Age) |
21320987 |
| 1816 |
Multiple System Atrophy |
Habit |
Smoking |
|
Human |
Smoking |
RF |
≥40 pack-years |
20623770 |
| 1193 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
11761476 |
| 1225 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
24788751 |
| 1370 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Current smokers (Adjusted for Age) |
21320987 |
| 2826 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Current smoker(Adjustment for education) |
10645818 |
| 1190 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
11359079 |
| 1222 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
24788751 |
| 1360 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Pack-years smoked ≤20 (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
| 1623 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
RF |
current smoking |
28806610 |
| 2745 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Combination recency and
dose:Current, ≥20 pack-years(Adjustment for education and alcohol consumption) |
10645818 |
| 4038 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
RF |
|
7969962 |
| 1219 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
23377703 |
| 1357 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Former smokers (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
| 2571 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Duration of smoking ≥20 years(Adjustment for education and alcohol consumption) |
10645818 |
| 4035 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
RF |
|
20975015 |
| 1187 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
11359079 |
| 1471 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Current smokers |
21187587 |
| 2506 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Duration of smoking ≥20 years(Adjustment for education) |
10645818 |
| 1184 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
9921857 |
| 1216 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
20603187 |
| 1346 |
Motor Neuron Disease |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Ever smokers |
22559076 |
| 49 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
Not Related |
|
1550089 |
| 371 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
33435977 |
| 1213 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
20220126 |
| 1245 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
29057010 |
| 1421 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Pack-years smoked 21-35 (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
| 1210 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
20175761 |
| 1408 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Pack-years smoked 21-35 (Adjusted for Age) |
21320987 |
| 2288 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Daily smoker |
9346343 |
| 330 |
Multiple System Atrophy |
Habit |
Smoking |
|
Human |
Smoking |
Not Related |
|
10636135 |
| 1023 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
30792733 |
| 1207 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
20175761 |
| 1239 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
26952952 |
| 1400 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Former smokers (Adjusted for Age) |
21320987 |
| 3510 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
RF |
|
2754163 |
| 1204 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
16542169 |
| 1236 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
25925389 |
| 1396 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Pack-years smoked ≤20 (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
| 2186 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Current(Adj. OR) |
17923612 |
| 3507 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
RF |
in Mongolian males aged over 55 years |
25657695 |
| 327 |
Frontotemporal Dementia |
Habit |
Smoking |
|
Human |
Smoking |
Not Related |
|
28946566 |
| 1385 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Ever smokers (Adjusted for Age) |
21320987 |
| 1975 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
|
30786056 |
| 3111 |
Tourette Syndrome |
Habit |
Smoking |
|
Human |
Smoking |
RF |
maternal smoking |
20654033 |
| 273 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
Not Related |
|
17106211 |
| 852 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
19540050 |
| 1201 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
15521056 |
| 2963 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Combination recency and dose:Current, <20 pack years(Adjustment for education) |
10645818 |
| 773 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
34649886 |
| 1198 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
The inverse correlation between Parkinson's disease risk and smoking as well as the trend of gradient dose response is again observed in our study. |
12964791 |
| 1376 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Former smokers (Adjusted for Age) |
21320987 |
| 1195 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
12847151 |
| 1227 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
24788751 |
| 1372 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Ever smokers (Adjusted for Age) |
21320987 |
| 2899 |
Multiple System Atrophy |
Habit |
Smoking |
|
Human |
Smoking |
RF |
≥40 pack-years |
20623770 |
| 646 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
34649886 |
| 1192 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
11574106 |
| 1224 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
24788751 |
| 1369 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
RF |
|
35532912 |
| 2815 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Combination recency and
dose:Current, ≥20 pack-years(Adjustment for education and alcohol consumption) |
10645818 |
| 496 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
Light smoker |
9346343 |
| 1189 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
11359079 |
| 1221 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
24788751 |
| 1359 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Ever smokers (Adjusted for Age, Body Mass Index, Physical Activity, and Education) |
21320987 |
| 2695 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Bulbar cases |
19922125 |
| 4037 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
RF |
|
9652667 |
| 1352 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Ever smokers (Adjusted for Age) |
21320987 |
| 1477 |
Alzheimer's Disease |
Habit |
Smoking |
|
Human |
Smoking |
RF |
smoking more than 2 packs a day |
20975015 |
| 2570 |
Amyotrophic Lateral Sclerosis |
Habit |
Smoking |
|
Human |
Smoking |
RF |
Cumulative pack-years≥20 pack-years(Adjustment for education and alcohol consumption) |
10645818 |
| 1186 |
Parkinson disease |
Habit |
Smoking |
|
Human |
Smoking |
PF |
|
11359079 |