RF_ID |
Disease Name |
2ndClass |
3rdClass |
4thClass |
Species |
RF_Name |
Association |
Condition |
PMID |
4177 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
RF |
|
20547628 |
323 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
Not Related |
Except for brain and vertebral column |
9660576 |
317 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
Not Related |
|
19193271 |
314 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
Not Related |
|
19193271 |
1118 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
PF |
|
12196646 |
311 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
Not Related |
|
19193271 |
4182 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
RF |
|
20547628 |
4179 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
RF |
|
20547628 |
322 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
Not Related |
|
9660576 |
316 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
Not Related |
|
19193271 |
313 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
Not Related |
|
19193271 |
1117 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
PF |
|
9660576 |
310 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
Not Related |
|
19193271 |
4184 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
RF |
|
20547628 |
4181 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
RF |
|
20547628 |
4178 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
RF |
|
20547628 |
324 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
Not Related |
|
9660576 |
315 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
Not Related |
|
19193271 |
1119 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
PF |
|
12196646 |
312 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
Not Related |
|
19193271 |
309 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
Not Related |
|
19193271 |
4183 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
RF |
|
20547628 |
4180 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical types |
RF |
|
20547628 |
1890 |
Amyotrophic Lateral Sclerosis |
Medical methods |
Medicines |
lipid-lowering drugs |
Human |
HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase (HMGCR) inhibitors |
RF |
|
37688479 |
902 |
Alzheimer's Disease |
Medical methods |
Medicines |
Antidiabetic |
Human |
Glucagon-like peptide 1 (GLP-1) agonists |
PF |
|
35128745 |
442 |
Alzheimer's Disease |
Medical methods |
Medicines |
Antidiabetic |
Human |
metformin |
PF |
Type 2 diabetes mellitus (T2DM) |
36109050 |
2528 |
Parkinson disease |
Medical methods |
Medicines |
anticholinergic drugs |
Human |
anticholinergic drugs |
RF |
|
37357543 |
1468 |
Parkinson disease |
Medical methods |
Medicines |
Neuroleptics |
Human |
antidepressants |
RF |
|
35748105 |
919 |
Parkinson disease |
Medical methods |
Medicines |
targeted medicine |
Human |
LRRK2 inhibition |
PF |
|
35675433 |
1458 |
Alzheimer's Disease |
Medical methods |
Medicines |
Antidiabetic |
Human |
insulin |
RF |
Type 2 diabetes mellitus (T2DM) |
37095270 |
1465 |
Alzheimer's Disease |
Medical methods |
Medicines |
Antidiabetic |
Human |
Pioglitazone |
RF |
Type 2 diabetes mellitus (T2DM) |
37095270 |
429 |
Alzheimer's Disease |
Medical methods |
Surgical therapy |
|
Human |
Cataract surgery |
PF |
|
34870676 |
409 |
Alzheimer's Disease |
Medical methods |
Surgical therapy |
|
Human |
Cataract surgery |
PF |
|
35940935 |
483 |
Alzheimer's Disease |
Medical methods |
other |
|
Human |
inpatient status |
PF |
|
35196953 |
484 |
Alzheimer's Disease |
Medical methods |
Medicines |
Neuroleptics |
Human |
anxiolytics |
PF |
|
35196953 |
1459 |
Parkinson disease |
Medical methods |
Medicines |
Neuroleptics |
Human |
anxiolytics |
RF |
|
35748105 |
1831 |
Alzheimer's Disease |
Medical methods |
Medicines |
Antihypertensive |
Human |
hypertension medication |
RF |
|
35196953 |
1836 |
Alzheimer's Disease |
Medical methods |
Medicines |
Neuroleptics |
Human |
antipsychotics |
RF |
|
35196953 |
1779 |
Alzheimer's Disease |
Medical methods |
Medicines |
Analgesic and anti-inflammatory drugs |
Human |
Muscle relaxant |
RF |
|
36641664 |
1778 |
Alzheimer's Disease |
Medical methods |
Medicines |
Analgesic and anti-inflammatory drugs |
Human |
Muscle relaxant |
RF |
|
36641664 |
1775 |
Alzheimer's Disease |
Medical methods |
Medicines |
Analgesic and anti-inflammatory drugs |
Human |
Muscle relaxant |
RF |
|
36641664 |
1446 |
Tuberous sclerosis complex |
Medical methods |
Medicines |
|
Human |
administration of multiple antiepileptic drugs |
RF |
|
20113608 |
761 |
Amyotrophic Lateral Sclerosis |
Medical methods |
Medicines |
Antidiabetic |
Human |
antidiabetics |
PF |
|
32097525 |
551 |
Parkinson disease |
Medical methods |
Medicines |
|
Human |
anti-histamines |
PF |
|
34494887 |
1776 |
Alzheimer's Disease |
Medical methods |
Medicines |
Neuroleptics |
Human |
benzodiazepine and related drug (BZDR) |
RF |
|
29851063 |
2474 |
Progressive Supranuclear Palsy |
Medical methods |
Medicines |
|
Human |
beta-blocker use |
RF |
|
31420308 |
3399 |
Parkinson disease |
Medical methods |
Medicines |
|
rat |
cinnarizine(a calcium antagonist that produces human parkinsonism) |
RF |
(a calcium antagonist that produces human parkinsonism) |
15993444 |
435 |
Parkinson disease |
Medical methods |
Non-pharmaceutical therapy |
|
Human |
deep brain stimulation (DBS) treatment |
PF |
|
33278869 |
870 |
Alzheimer's Disease |
Medical methods |
Medicines |
Analgesic and anti-inflammatory drugs |
mice |
dexibuprofen (DXI) |
PF |
|
34294142 |
401 |
Parkinson disease |
Medical methods |
Medicines |
Antidiabetic |
Human |
Dipeptidyl peptidase-4 (DPP4) inhibitors |
PF |
|
33895825 |
397 |
Parkinson disease |
Medical methods |
Medicines |
Antidiabetic |
Human |
Dipeptidyl peptidase-4 (DPP4) inhibitors |
PF |
in diabetic patients |
38110464 |
1884 |
Parkinson disease |
Medical methods |
Medicines |
|
Human |
duration of exposure to levodopa |
RF |
|
23836370 |
1885 |
Parkinson disease |
Medical methods |
Medicines |
|
Human |
duration of exposure to levodopa |
RF |
|
23836370 |
819 |
Amyotrophic Lateral Sclerosis |
Medical methods |
Medicines |
|
Human |
Duration of OCP(oral contraceptive) use (per year) |
PF |
female |
28835399 |
519 |
Alzheimer's Disease |
Medical methods |
Medicines |
|
Human |
Estrogen-replacement therapy |
PF |
postmenopausal women |
9566385 |
3102 |
Frontotemporal Dementia |
Medical methods |
Medicines |
|
Human |
Excluding specific neuroprotective supplements |
RF |
after onset of disease |
33138082 |
3053 |
Parkinson disease |
Medical methods |
surgical therapy |
|
Human |
general anesthesia |
RF |
|
32943485 |
2886 |
Amyotrophic Lateral Sclerosis |
Medical methods |
medical history |
|
Human |
having a past history of CS/SSM |
RF |
|
17538776 |
2952 |
Amyotrophic Lateral Sclerosis |
Medical methods |
surgical therapy |
|
Human |
having surgical treatment for CS/SSM |
RF |
|
17538776 |
432 |
Alzheimer's Disease |
Medical methods |
Non-pharmaceutical therapy |
|
Human |
Hearing aid |
PF |
hearing-impaired adults |
33614893 |
2611 |
Multiple System Atrophy |
Medical methods |
Medicines |
|
Human |
Herbal medications |
RF |
|
20623770 |
1802 |
Multiple System Atrophy |
Medical methods |
Medicines |
|
Human |
Herbal medications |
RF |
|
20623770 |
1766 |
Creutzfeldt-Jakob disease |
Medical methods |
Non-pharmaceutical therapy |
|
Human |
hGH(human cadaver-sourced growth hormone) treatment |
RF |
Proportion of doses risk category 1 (batches 1, 2, 3, 4, 7, 21, 26) |
30045957 |
1637 |
Creutzfeldt-Jakob disease |
Medical methods |
Non-pharmaceutical therapy |
|
Human |
hGH(human cadaver-sourced growth hormone) treatment |
RF |
|
30045957 |
1758 |
Creutzfeldt-Jakob disease |
Medical methods |
Non-pharmaceutical therapy |
|
Human |
hGH(human cadaver-sourced growth hormone) treatment |
RF |
Proportion of doses risk category 3 (batches 5, 6, 8, 9, 11, 14, 15, 16, 17, 19, 20, 22, 23, 25, 27) |
30045957 |
1728 |
Creutzfeldt-Jakob disease |
Medical methods |
Non-pharmaceutical therapy |
|
Human |
hGH(human cadaver-sourced growth hormone) treatment |
RF |
Proportion of doses risk category 2 (batches 10, 12, 13, 18, 24) |
30045957 |
514 |
Amyotrophic Lateral Sclerosis |
Medical methods |
Medicines |
|
Human |
Immunosuppressive drugs |
PF |
|
25059395 |
2733 |
Alzheimer's Disease |
Medical methods |
Medicines |
Neuroleptics |
Human |
inappropriate use anti-dementia drugs |
RF |
|
32251456 |
3471 |
Amyotrophic Lateral Sclerosis |
Medical methods |
Non-pharmaceutical therapy |
|
Human |
inhalation of BMAA, DAB, and other aerosolized cyanotoxins |
RF |
|
19929742 |
2155 |
Alzheimer's Disease |
Medical methods |
Medicines |
Neuroleptics |
Human |
irregular medication use anti-dementia drugs |
RF |
|
32251456 |
2423 |
Tourette Syndrome |
Medical methods |
other |
|
Human |
longer delay of treatment |
RF |
|
20654033 |
1882 |
Parkinson disease |
Medical methods |
Medicines |
Antihypertensive |
Human |
metoprolol |
RF |
|
34598055 |
3889 |
Tuberous sclerosis complex |
Medical methods |
Medicines |
|
Human |
multiple antiepileptic drugs |
RF |
|
33225634 |
566 |
Alzheimer's Disease |
Medical methods |
Medicines |
Analgesic and anti-inflammatory drugs |
Human |
no chronic use of nonsteroidal anti-inflammatory drugs |
PF |
|
18446027 |
392 |
Alzheimer's Disease |
Medical methods |
Medicines |
Analgesic and anti-inflammatory drugs |
Human |
Non-aspirin NSAIDS |
PF |
|
33435977 |
373 |
Parkinson disease |
Medical methods |
Medicines |
Analgesic and anti-inflammatory drugs |
Human |
Non-aspirin NSAIDS |
PF |
|
33435977 |
400 |
Parkinson disease |
Medical methods |
Medicines |
|
Human |
non-hydroxychloroquine immunosuppressant therapy |
PF |
Sj?gren syndrome (SS) |
30946325 |
2185 |
Creutzfeldt-Jakob disease |
Medical methods |
surgical therapy |
|
Human |
Number of surgical procedures |
RF |
>=3 times |
12196646 |
2464 |
Creutzfeldt-Jakob disease |
Medical methods |
surgical therapy |
|
Human |
Number of surgical procedures |
RF |
2 times |
12196646 |
2314 |
Creutzfeldt-Jakob disease |
Medical methods |
surgical therapy |
|
Human |
Number of surgical procedures |
RF |
1 time |
12196646 |
702 |
Amyotrophic Lateral Sclerosis |
Medical methods |
Medicines |
contraceptive pills |
Human |
OCP(oral contraceptive) |
PF |
female |
28835399 |
2930 |
Amyotrophic Lateral Sclerosis |
Medical methods |
Medicines |
contraceptive pills |
Human |
OCP(oral contraceptive) |
RF |
postmenopausal |
37493444 |
2456 |
Tuberous sclerosis complex |
Medical methods |
medical history |
|
Human |
poor control of subsequent seizures after IS |
RF |
|
16043792 |
3499 |
Alzheimer's Disease |
Medical methods |
Medicines |
Gastrointestinal drugs |
Human |
Proton pump inhibitors (PPIs) |
RF |
Chronic consumption of PPIs |
20456731 |
1777 |
Parkinson disease |
Medical methods |
Medicines |
Gastrointestinal drugs |
Human |
Proton pump inhibitors (PPIs) |
RF |
1-year lag period was applied between PPI exposure and PD development |
38096177 |
2576 |
Creutzfeldt-Jakob disease |
Medical methods |
medical history |
|
Human |
regular medication |
RF |
|
19144172 |
469 |
Alzheimer's Disease |
Medical methods |
Medicines |
Statin |
Human |
Statin therapy |
PF |
|
32753051 |
897 |
Parkinson disease |
Medical methods |
Medicines |
Statin |
Human |
statin use |
PF |
|
34275907 |
817 |
Alzheimer's Disease |
Medical methods |
Medicines |
Statin |
Human |
statin use |
PF |
|
33804752 |
2478 |
Parkinson disease |
Medical methods |
Medicines |
Statin |
Human |
statin use |
RF |
|
34347020 |
398 |
Alzheimer's Disease |
Medical methods |
Medicines |
Statin |
Human |
statin use |
PF |
|
20533968 |
1580 |
Alzheimer's Disease |
Medical methods |
surgical therapy |
|
Human |
Underwent Surgery under Neuraxial Anesthesia |
RF |
|
34945858 |
766 |
Multiple System Atrophy |
Medical methods |
Medicines |
Analgesic and anti-inflammatory drugs |
Human |
use of non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) |
PF |
Cumulative doses were used to divide observations into tertiles creating 3 groups of equal size (T1–3) based on the consumption in defined daily dose(DDD) with T1 representing the group with the lowest use and T3 the highest. |
31661696 |
735 |
Multiple System Atrophy |
Medical methods |
Medicines |
Analgesic and anti-inflammatory drugs |
Human |
use of non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) |
PF |
|
31661696 |
645 |
Multiple System Atrophy |
Medical methods |
Medicines |
Analgesic and anti-inflammatory drugs |
Human |
use of non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) |
PF |
Cumulative doses were used to divide observations into tertiles creating 3 groups of equal size (T1–3) based on the consumption in DDDs with T1 representing the group with the lowest use and T3 the highest. |
31661696 |
583 |
Amyotrophic Lateral Sclerosis |
Medical methods |
Medicines |
Statin |
Human |
Use of statins |
PF |
|
25059395 |
1993 |
Amyotrophic Lateral Sclerosis |
Medical methods |
Medicines |
Statin |
Human |
Use of statins |
RF |
|
32097525 |
803 |
Parkinson disease |
Medical methods |
Medicines |
|
Human |
β-agonists |
PF |
|
34598055 |
1940 |
Parkinson disease |
Medical methods |
Medicines |
|
Human |
β-antagonists |
RF |
|
34598055 |
361 |
Progressive Supranuclear Palsy |
Medical methods |
Medicines |
Analgesic and anti-inflammatory drugs |
Human |
Non-steroidal anti-inflammatory drug (except
aspirin) |
Not Related |
|
19864660 |
539 |
Parkinson disease |
Medical methods |
Medicines |
Analgesic and anti-inflammatory drugs |
Human |
Aspirin |
PF |
|
34494887 |
360 |
Progressive Supranuclear Palsy |
Medical methods |
Medicines |
Analgesic and anti-inflammatory drugs |
Human |
Aspirin |
Not Related |
|
19864660 |
1125 |
Multiple System Atrophy |
Medical methods |
Medicines |
Analgesic and anti-inflammatory drugs |
Human |
Aspirin |
PF |
|
18307243 |
359 |
Progressive Supranuclear Palsy |
Medical methods |
Medicines |
Analgesic and anti-inflammatory drugs |
Human |
Anti-inflammatory agent |
Not Related |
|
19864660 |
1324 |
Parkinson disease |
Medical methods |
Medicines |
Asthma drugs |
Human |
β2-agonists |
PF |
|
30311974 |
1323 |
Parkinson disease |
Medical methods |
Medicines |
Asthma drugs |
Human |
β2-agonists |
PF |
|
30311974 |
1325 |
Parkinson disease |
Medical methods |
Medicines |
Asthma drugs |
Human |
β2-agonists |
PF |
|
30311974 |
4373 |
Parkinson disease |
Medical methods |
Medicines |
|
Human |
Propranolol |
RF |
|
30311974 |
2237 |
Parkinson disease |
Medical methods |
Medicines |
|
Human |
Propranolol |
RF |
|
34598055 |
4372 |
Parkinson disease |
Medical methods |
Medicines |
|
Human |
Propranolol |
RF |
|
30311974 |
1322 |
Parkinson disease |
Medical methods |
Health examination |
|
Human |
Dental Scaling |
PF |
Individuals aged 40-69 years, individuals without periodontal inflammatory disease (PID) showed a protective effect of dental scaling against PD development |
30049978 |
1321 |
Parkinson disease |
Medical methods |
Medicines |
Antidiabetic |
Human |
Glitazone(GTZ) |
PF |
People with diabetes |
28861893 |
4371 |
Parkinson disease |
Medical methods |
Surgical therapy |
|
Human |
Dental Amalgam Fillings |
RF |
History of Dental Amalgam Fillings |
27906991 |
4370 |
Parkinson disease |
Medical methods |
Medicines |
Neuroleptics |
Human |
Methamphetamine/amphetamine abuse |
RF |
(ICD-9-CM 304.4, 305.7, 969.7, E854.2) |
25479916 |
4368 |
Parkinson disease |
Medical methods |
Medicines |
hypnagogue |
Human |
Zolpidem |
RF |
Zolpidem use in patients with sleep disturbance |
25124550 |
4369 |
Parkinson disease |
Medical methods |
Medicines |
hypnagogue |
Human |
Zolpidem |
RF |
Zolpidem use in patients with sleep disturbance |
25124550 |
1320 |
Parkinson disease |
Medical methods |
Medicines |
Antihypertensive |
Human |
ARBs(angiotensin receptor blockers) |
PF |
Antihypertensive agents |
24910980 |
1319 |
Parkinson disease |
Medical methods |
Medicines |
Antihypertensive |
Human |
ACEIs(angiotensin converting enzyme inhibitors) |
PF |
Antihypertensive agents |
24910980 |
1318 |
Parkinson disease |
Medical methods |
Medicines |
Antihypertensive |
Human |
CCB(calcium channel blockers) |
PF |
Antihypertensive agents ;Centrally-acting dihydropyridine CCB use |
24910980 |
4367 |
Parkinson disease |
Medical methods |
Medicines |
Neuroleptics |
Human |
Benzamides |
RF |
Neuroleptics |
23019267 |
4366 |
Parkinson disease |
Medical methods |
Medicines |
Neuroleptics |
Human |
Phenothiazines |
RF |
Neuroleptics |
23019267 |
4365 |
Parkinson disease |
Medical methods |
Medicines |
Neuroleptics |
Human |
Neuroleptics |
RF |
All Neuroleptics |
23019267 |
2131 |
Alzheimer's Disease |
Medical methods |
Medicines |
|
Human |
Polypharmacy |
RF |
|
32251456 |
4362 |
Parkinson disease |
Medical methods |
Medicines |
|
Human |
Polypharmacy |
RF |
|
21951955 |
4364 |
Parkinson disease |
Medical methods |
Medicines |
|
Human |
Polypharmacy |
RF |
|
21951955 |
4361 |
Parkinson disease |
Medical methods |
Medicines |
|
Human |
Polypharmacy |
RF |
|
21951955 |
4363 |
Parkinson disease |
Medical methods |
Medicines |
|
Human |
Polypharmacy |
RF |
|
21951955 |
1315 |
Parkinson disease |
Medical methods |
Medicines |
Analgesic and anti-inflammatory drugs |
Human |
Ibuprofen |
PF |
There was a dose-response relationship between tablets of ibuprofen taken per week and PD risk (p trend = 0.01). |
21368281 |
1313 |
Parkinson disease |
Medical methods |
Medicines |
Antihypertensive |
Human |
L-type calcium channel blockers |
PF |
|
20437557 |
1312 |
Parkinson disease |
Medical methods |
Medicines |
Antihypertensive |
Human |
Antihypertensives(Calcium channel blockers) |
PF |
|
18256367 |
321 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Organ transplantation |
Not Related |
Tanspant recipient |
10073510 |
320 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Dental treament |
Not Related |
|
10073510 |
318 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Dental treament |
Not Related |
|
17299423 |
717 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
PF |
undergo surgery |
18257690 |
676 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
PF |
Surgery at any time |
3066847 |
2992 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
RF |
orthopaedic surgery |
19144172 |
2692 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
RF |
ophthalmological surgery (> 1980) |
19144172 |
4195 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
RF |
|
12196646 |
4192 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
RF |
|
10073510 |
2515 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
RF |
|
10073510 |
2329 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
RF |
undergo surgery |
18257690 |
2241 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
RF |
undergo surgery;proxy informants acted only on behalf of case subjects (inconsistent data ascertainment) |
18257690 |
2174 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
RF |
|
18843192 |
325 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
Not Related |
|
12196646 |
2117 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
RF |
Gynecologic |
12196646 |
675 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
PF |
Appendectomy |
12196646 |
2856 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
RF |
orthopaedic surgery (> 1980) |
19144172 |
528 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
PF |
Tonsillectomy |
12196646 |
4194 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
RF |
|
12196646 |
2669 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
RF |
predating clinical onset by 1 or more years |
18843192 |
4191 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
RF |
|
10073510 |
701 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
PF |
undergo surgery;used proxy informants to acquire information about case subjects and control subjects (consistent ascertainment) |
18257690 |
2668 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
RF |
at a 1- to 9-year time lag |
18843192 |
4193 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
RF |
|
12196646 |
4189 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
RF |
|
18843192 |
2313 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgery |
RF |
Any surgery |
12196646 |
4188 |
Creutzfeldt-Jakob disease |
Medical methods |
Medicines |
|
Human |
Medication |
RF |
|
19144172 |
4187 |
Creutzfeldt-Jakob disease |
Medical methods |
Health examination |
|
Human |
GP visits |
RF |
|
19144172 |
4186 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Orthopaedic surgery |
RF |
|
19144172 |
4185 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Ophthalmological surgery |
RF |
|
19144172 |
4176 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Blood transfusion |
RF |
|
21214582 |
319 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Blood transfusion |
Not Related |
|
10073510 |
308 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Orthodontics |
Not Related |
|
23222357 |
307 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Haemostasis |
Not Related |
|
23222357 |
306 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Intravenous sedation |
Not Related |
|
23222357 |
305 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Surgical extractions |
Not Related |
|
23222357 |
304 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Periodontal treatment |
Not Related |
|
23222357 |
303 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Other minor oral surgery |
Not Related |
|
23222357 |
302 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Root canal treatment |
Not Related |
|
23222357 |
301 |
Creutzfeldt-Jakob disease |
Medical methods |
Non-pharmaceutical therapy |
|
Human |
Non-surgical extractions |
Not Related |
|
23222357 |
300 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Extensive fillings |
Not Related |
|
23222357 |
299 |
Creutzfeldt-Jakob disease |
Medical methods |
Surgical therapy |
|
Human |
Minimal fillings |
Not Related |
|
23222357 |
298 |
Creutzfeldt-Jakob disease |
Medical methods |
Health examination |
|
Human |
Basic periodontal examination |
Not Related |
|
23222357 |
290 |
Amyotrophic Lateral Sclerosis |
Medical methods |
Surgical therapy |
|
Human |
Surgical operations |
Not Related |
|
1798425 |
1082 |
Alzheimer's Disease |
Medical methods |
Non-pharmaceutical therapy |
|
Human |
Music therapy |
PF |
|
19628939 |
1081 |
Alzheimer's Disease |
Medical methods |
Non-pharmaceutical therapy |
|
Human |
Cognitive stimulation therapy |
PF |
|
20713437 |
1076 |
Alzheimer's Disease |
Medical methods |
Medicines |
Statin |
Human |
Atorvastatin |
PF |
|
15974900 |
68 |
Alzheimer's Disease |
Medical methods |
Medicines |
Statin |
Human |
Simvastatin |
Not Related |
|
21795660 |
66 |
Alzheimer's Disease |
Medical methods |
Medicines |
Analgesic and anti-inflammatory drugs |
Human |
NSAIDs |
Not Related |
|
18519870 |
343 |
Parkinson disease |
Medical methods |
Medicines |
Analgesic and anti-inflammatory drugs |
Human |
NSAIDs |
Not Related |
|
17851257 |
67 |
Alzheimer's Disease |
Medical methods |
Medicines |
Analgesic and anti-inflammatory drugs |
Human |
NSAIDs |
Not Related |
|
10192221 |
1078 |
Alzheimer's Disease |
Medical methods |
Medicines |
Statin |
Human |
Statin |
PF |
|
18931004 |
1075 |
Alzheimer's Disease |
Medical methods |
Medicines |
Statin |
Human |
Statin |
PF |
|
25408208 |
378 |
Alzheimer's Disease |
Medical methods |
Medicines |
Statin |
Human |
Statin |
PF |
|
33435977 |
1317 |
Parkinson disease |
Medical methods |
Medicines |
Statin |
Human |
Statin |
PF |
Statin treatment |
24304212 |
1314 |
Parkinson disease |
Medical methods |
Medicines |
Statin |
Human |
Statin |
PF |
Short-term (
20629142 |
|
1080 |
Alzheimer's Disease |
Medical methods |
Medicines |
Statin |
Human |
Statin |
PF |
|
19595865 |
1077 |
Alzheimer's Disease |
Medical methods |
Medicines |
Statin |
Human |
Statin |
PF |
|
14739574 |
1316 |
Parkinson disease |
Medical methods |
Medicines |
Statin |
Human |
Statin |
PF |
|
22410446 |
1788 |
Parkinson disease |
Medical methods |
Medicines |
Statin |
Human |
Statin |
RF |
hyperlipidemia |
35276584 |
1079 |
Alzheimer's Disease |
Medical methods |
Medicines |
Statin |
Human |
Statin |
PF |
|
20533968 |
1774 |
Parkinson disease |
Medical methods |
Medicines |
Statin |
Human |
Statin |
RF |
hyperlipidemia |
35276584 |
384 |
Parkinson disease |
Medical methods |
Medicines |
Statin |
Human |
Statin |
PF |
|
33435977 |
3059 |
Creutzfeldt-Jakob disease |
Medical methods |
Health examination |
|
Human |
regular GP visits |
RF |
|
19144172 |
4258 |
Parkinson disease |
Medical methods |
Surgical therapy |
|
Human |
General anaesthesia |
RF |
|
11903115 |