RF_ID |
Disease Name |
2ndClass |
3rdClass |
4thClass |
Species |
RF_Name |
Association |
Condition |
PMID |
1554 |
Amyotrophic Lateral Sclerosis |
Physical fitness |
Height |
|
Human |
taller people |
RF |
UK |
34675682 |
1559 |
Parkinson disease |
Physical fitness |
strength |
|
Human |
grip strength |
RF |
|
36912851 |
1435 |
Alzheimer's Disease |
Physical fitness |
|
|
Human |
Difficulty Upper and Lower Body |
RF |
|
36031903 |
1425 |
Alzheimer's Disease |
Physical fitness |
|
|
Human |
Difficulty Upper Body |
RF |
|
36031903 |
1430 |
Alzheimer's Disease |
Physical fitness |
|
|
Human |
Difficulty Climbing Stairs |
RF |
|
36031903 |
1618 |
Alzheimer's Disease |
Physical fitness |
|
|
Human |
self-perceived health (SPH) |
RF |
|
35025095 |
3907 |
Frontotemporal Dementia |
Physical fitness |
|
|
Human |
heart health |
RF |
|
35767471 |
3379 |
Alzheimer's Disease |
Physical fitness |
|
|
Human |
age-associated decline in health status |
RF |
the nontraditional risk factors index [FI-NTRF] was constructed for predict Alzheimer disease and dementia |
21753161 |
1871 |
Amyotrophic Lateral Sclerosis |
Physical fitness |
BMI |
|
Human |
BMI history |
RF |
OR controlled for age, sex, duration of school education, and smoking status |
28975435 |
800 |
Amyotrophic Lateral Sclerosis |
Physical fitness |
BMI |
|
Human |
BMI history |
PF |
OR controlled for age, sex, duration of school education, and smoking status |
28975435 |
1907 |
Amyotrophic Lateral Sclerosis |
Physical fitness |
BMI |
|
Human |
BMI history |
RF |
OR controlled for age, sex, duration of school education, and smoking status |
28975435 |
1876 |
Amyotrophic Lateral Sclerosis |
Physical fitness |
BMI |
|
Human |
BMI history |
RF |
OR controlled for age, sex, duration of school education, and smoking status |
28975435 |
1965 |
Amyotrophic Lateral Sclerosis |
Physical fitness |
BMI |
|
Human |
BMI(Body Mass Index) |
RF |
Low BMI(Body Mass Index) |
31155341 |
3458 |
Alzheimer's Disease |
Physical fitness |
BMI |
|
Human |
BMI(Body Mass Index) |
RF |
|
24596166 |
458 |
Alzheimer's Disease |
Physical fitness |
BMI |
|
Human |
BMI(Body Mass Index) |
PF |
|
32979926 |
1562 |
Alzheimer's Disease |
Physical fitness |
BMI |
|
Human |
BMI(Body Mass Index) |
RF |
after Hemodialysis Initiation; 18.5–25.0 |
30093374 |
1553 |
Alzheimer's Disease |
Physical fitness |
BMI |
|
Human |
BMI(Body Mass Index) |
RF |
after Hemodialysis Initiation; <18.5 |
30093374 |
3391 |
Alzheimer's Disease |
Physical fitness |
BMI |
|
Human |
BMI(Body Mass Index) |
RF |
intrinsic epigenetic age acceleration |
30167451 |
1538 |
Alzheimer's Disease |
Physical fitness |
BMI |
|
Human |
BMI(Body Mass Index) |
RF |
after Hemodialysis Initiation; 25.0–30.0 |
30093374 |
3390 |
Alzheimer's Disease |
Physical fitness |
BMI |
|
Human |
BMI(Body Mass Index) |
RF |
extrinsic epigenetic age acceleration |
30167451 |
1659 |
Alzheimer's Disease |
Physical fitness |
Weight |
|
Human |
experienced appreciable weight loss |
RF |
|
18835864 |
808 |
Alzheimer's Disease |
Physical fitness |
Height |
|
Human |
Height |
PF |
|
33718584 |
1499 |
Alzheimer's Disease |
Physical fitness |
|
|
Human |
Inability to ambulate |
RF |
after Hemodialysis Initiation |
30093374 |
3685 |
Amyotrophic Lateral Sclerosis |
Physical fitness |
BMI |
|
Human |
lower BMI |
RF |
|
32266542 |
1416 |
Alzheimer's Disease |
Physical fitness |
BMI |
|
Human |
Midlife BMI |
RF |
|
33435977 |
1457 |
Amyotrophic Lateral Sclerosis |
Physical fitness |
|
|
Human |
overall muscle strength |
RF |
Low overall muscle strength |
29285652 |
3858 |
Parkinson disease |
Physical fitness |
|
|
Human |
Postural stiffening(fatigue) |
RF |
|
34180424 |
1770 |
Alzheimer's Disease |
Physical fitness |
|
|
Human |
self-rated health |
RF |
poorer self-rated health |
34311955 |
1760 |
Alzheimer's Disease |
Physical fitness |
Weight |
|
Human |
underweight |
RF |
at age 30, 40, or 45 years |
18835864 |
1726 |
Alzheimer's Disease |
Physical fitness |
Weight |
|
Human |
weight gain |
RF |
between 30 and 50 years for any 5-year interval |
18835864 |
3734 |
Alzheimer's Disease |
Physical fitness |
Weight |
|
Human |
Weight loss |
RF |
|
33597012 |
3029 |
Alzheimer's Disease |
Physical fitness |
|
|
Human |
Yang-Deficient |
RF |
|
33907404 |
4261 |
Parkinson disease |
Physical fitness |
Obesity |
|
Human |
Central obesity |
RF |
|
15003958 |
4260 |
Parkinson disease |
Physical fitness |
Obesity |
|
Human |
Central obesity |
RF |
|
15003958 |
4259 |
Parkinson disease |
Physical fitness |
|
|
Human |
Increased triceps skinfold thickness measured in midlife |
RF |
Among the measures of adiposity,age-adjusted incidence of PD increased threefold from 3.7/10,000 person-years in the bottom quartile of TSF (1 to 5 mm) to 11.1/10,000 person-years in the top quartile (11 to 32 mm, p 0.001). |
12370461 |
1112 |
Amyotrophic Lateral Sclerosis |
Physical fitness |
Weight |
|
Human |
Weight |
PF |
|
31243073 |
1111 |
Amyotrophic Lateral Sclerosis |
Physical fitness |
BMI |
|
Human |
BMI |
PF |
|
31243073 |
4113 |
Amyotrophic Lateral Sclerosis |
Physical fitness |
BMI |
|
Human |
BMI |
RF |
|
31155341 |
1292 |
Parkinson disease |
Physical fitness |
BMI |
|
Human |
BMI |
PF |
|
16542169 |
1110 |
Amyotrophic Lateral Sclerosis |
Physical fitness |
BMI |
|
Human |
BMI |
PF |
|
31243073 |
1109 |
Amyotrophic Lateral Sclerosis |
Physical fitness |
BMI |
|
Human |
BMI |
PF |
|
31243073 |
410 |
Parkinson disease |
Physical fitness |
BMI |
|
Human |
BMI |
PF |
infection with hepatitis C virus (HCV) |
36872452 |
4263 |
Parkinson disease |
Physical fitness |
BMI |
|
Human |
BMI |
RF |
|
24633681 |
1293 |
Parkinson disease |
Physical fitness |
BMI |
|
Human |
BMI |
PF |
|
28609445 |
4112 |
Amyotrophic Lateral Sclerosis |
Physical fitness |
|
|
Human |
Physical fitness |
RF |
|
20852312 |
1294 |
Parkinson disease |
Physical fitness |
|
|
Human |
Physical fitness |
PF |
Physical fitness (high vs. low: hazard ratio: 0.239, 95% CI: 0.079-0.725, p?=?.011);Exercise capacity was
expressed as metabolic equivalents (METs) estimated
from peak treadmill speed and grade. |
29667433 |
50 |
Alzheimer's Disease |
Physical fitness |
BMI |
|
Human |
Genetic and hence lifelong low BMI |
Not Related |
|
28609829 |
4047 |
Alzheimer's Disease |
Physical fitness |
Weight |
|
Human |
Overweight in midlife |
RF |
To gain statistical power, we therefore applied a slightly different categorization with BMI dichotomized into two categories with the top 25% of the distribution defined as overweight (BMI ≥ 26.5; coded as 1) and all others defined as normal weight (coded as 0). |
19506566 |
1390 |
Alzheimer's Disease |
Physical fitness |
Obesity |
|
Human |
Obesity at midlife |
RF |
|
35532912 |
4046 |
Alzheimer's Disease |
Physical fitness |
Obesity |
|
Human |
Obesity at midlife |
RF |
|
16216938 |
2676 |
Frontotemporal Dementia |
Physical fitness |
Obesity |
|
Human |
Obesity |
RF |
|
30792733 |
655 |
Alzheimer's Disease |
Physical fitness |
Obesity |
|
Human |
Obesity |
PF |
CARTPT was identified to be shared by the anti-obesity drug targets and AD susceptibility genes |
33523009 |
386 |
Motor Neuron Disease |
Physical fitness |
Obesity |
|
Human |
Obesity |
PF |
BMI>=30 |
22559076 |
1531 |
Parkinson disease |
Physical fitness |
Obesity |
|
Human |
Obesity |
RF |
|
31019987 |
2694 |
Alzheimer's Disease |
Physical fitness |
Obesity |
|
Human |
Obesity |
RF |
|
30792733 |
2412 |
Amyotrophic Lateral Sclerosis |
Physical fitness |
Obesity |
|
Human |
Obesity |
RF |
|
27065942 |
3483 |
Alzheimer's Disease |
Physical fitness |
Obesity |
|
Human |
Obesity |
RF |
|
31191220 |
1393 |
Alzheimer's Disease |
Physical fitness |
Obesity |
|
Human |
Obesity |
RF |
|
26495049 |
2677 |
Frontotemporal Lobar Degeneration |
Physical fitness |
Obesity |
|
Human |
Obesity |
RF |
|
30792733 |
2030 |
Alzheimer's Disease |
Physical fitness |
Obesity |
|
Human |
Obesity |
RF |
CARTPT was identified to be shared by the anti-obesity drug targets and AD susceptibility genes |
33523009 |
716 |
Amyotrophic Lateral Sclerosis |
Physical fitness |
Obesity |
|
Human |
Obesity |
PF |
Unadjusted |
26030836 |
1764 |
Alzheimer's Disease |
Physical fitness |
Obesity |
|
Human |
Obesity |
RF |
being obese (BMI ≥30) at age 30, 40, or 45 years and jointly centrally obese (waist circumference ≥80th percentile) at age 30, 35, or 50 years |
18835864 |
4048 |
Alzheimer's Disease |
Physical fitness |
Obesity |
|
Human |
Obesity |
RF |
|
30792733 |
4045 |
Alzheimer's Disease |
Physical fitness |
Obesity |
|
Human |
Obesity |
RF |
|
30792733 |
3482 |
Alzheimer's Disease |
Physical fitness |
Obesity |
|
Human |
Obesity |
RF |
|
26324099 |
1392 |
Alzheimer's Disease |
Physical fitness |
Obesity |
|
Human |
Obesity |
RF |
|
29606955 |
2917 |
Alzheimer's Disease |
Physical fitness |
Obesity |
|
Human |
Obesity |
RF |
|
35587456 |